124 24 22MB
English Pages 386 [348] Year 2021
Acta Neurochirurgica Supplement 131
Bart Depreitere Geert Meyfroidt Fabian Güiza Editors
Intracranial Pressure and Neuromonitoring XVII
Acta Neurochirurgica Supplement 131 Series Editor Hans-Jakob Steiger Department of Neurosurgery Heinrich Heine University Düsseldorf, Germany
ACTA NEUROCHIRURGICA’s Supplement Volumes provide a unique opportunity to publish the content of special meetings in the form of a Proceedings Volume. Proceedings of international meetings concerning a special topic of interest to a large group of the neuroscience community are suitable for publication in ACTA NEUROCHIRURGICA. Links to ACTA NEUROCHIRURGICA’s distribution network guarantee wide dissemination at a comparably low cost. The individual volumes should comprise between 120 and max. 250 printed pages, corresponding to 20-50 papers. It is recommended that you get in contact with us as early as possible during the preparatory stage of a meeting. Please supply a preliminary program for the planned meeting. The papers of the volumes represent original publications. They pass a peer review process and are listed in PubMed and other scientific databases. Publication can be effected within 6 months. Hans-Jakob Steiger is the Editor of ACTA NEUROCHIRURGICA’s Supplement Volumes. Springer Verlag International is responsible for the technical aspects and calculation of the costs. If you decide to publish your proceedings in the Supplements of ACTA NEUROCHIRURGICA, you can expect the following: • An editing process with editors both from the neurosurgical community and professional language editing. After your book is accepted, you will be assigned a developmental editor who will work with you as well as with the entire editing group to bring your book to the highest quality possible. • Effective text and illustration layout for your book. • Worldwide distribution through Springer-Verlag International’s distribution channels. More information about this series at http://www.springer.com/series/4
Bart Depreitere • Geert Meyfroidt Fabian Güiza Editors
Intracranial Pressure and Neuromonitoring XVII
Editors Bart Depreitere Department of Neurosurgery University Hospitals Leuven Leuven Belgium
Geert Meyfroidt Department of Intensive Care Medicine University Hospitals Leuven Leuven Belgium
Fabian Güiza Department of Intensive Care Medicine University Hospitals Leuven Leuven Belgium
ISSN 0065-1419 ISSN 2197-8395 (electronic) Acta Neurochirurgica Supplement ISBN 978-3-030-59435-0 ISBN 978-3-030-59436-7 (eBook) https://doi.org/10.1007/978-3-030-59436-7 © Springer Nature Switzerland AG 2021, corrected publication 2021, 2022 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
Preface (17th International Conference on Intracranial Pressure and Neuromonitoring)
Since its first edition in 1972, the International Symposium on Intracranial Pressure and Neuromonitoring (also called the ICP Conference) has been an excellent high level and multidisciplinary forum for the exchange of ideas and results on clinical management and research associated with the monitoring of intracranial pressure, cerebrovascular autoregulation, and additional physiological and metabolic signals of the brain relevant to conditions as traumatic brain injury, subarachnoid hemorrhage, stroke, spinal cord injury, hydrocephalus, and cerebrovascular fluid disorders. What initially started with the investigation of the information concealed within the ICP signal and the association with clinical variables, has expanded over the past decades to include advanced imaging methods, metabolic monitoring, and sophisticated mathematical modeling. One of the great strengths of the ICP Conference has always been that it brings together all the disciplines involved and facilitates direct communication between neuroscientists, engineers, computer scientists, mathematicians, and clinicians from a variety of backgrounds. In all of the fascinating developments that were subjects of the ICP Conferences, the dedication to those who suffer devastating acute brain and spinal cord injuries and cerebrospinal fluid disorders has always remained central. The 17th ICP Conference was held in Leuven, Belgium from September 8 through 11 2019 and we were proud to host it. The Conference welcomed 360 delegates from all over the world. It featured 202 contributed presentations and attained a high level of interaction and discussion. In addition, it hosted four satellite events, amongst which a data challenge, ICM+ users group meeting, annual meeting of the Brain-IT group and the 9th annual meeting of CARNet. A cross-section of the research presented in Leuven is included in this Proceedings volume. The 70 papers that were selected for this volume give an accurate insight into current thought and direction in the research on brain monitoring. We are happy to present them and are confident that these contributions will inspire future work and ideas. Therefore, we are already looking forward to the 18th edition of the ICP Conference, that will take place in Cape Town, South Africa in 2022, at which the 50th anniversary of the ICP Conference will be celebrated. The editors wish to thank the ICP2019 Scientific Committee, the International Advisory Committee and Mrs. Marie-Laure Bettens and Ann Moerenhout for their enormous administrative support. Leuven, Belgium
Bart Depreitere Geert Meyfroidt Fabian Güiza
v
Contents
Part I Neuromonitoring and Management in Adult Traumatic Brain Injury icrocirculatory Biomarkers of Secondary Cerebral Ischemia M in Traumatic Brain Injury ���������������������������������������������������������������������������������������������� 3 Alex Trofimov, Antony Dubrovin, Dmitry Martynov, Darya Agarkova, Ksenia Trofimova, Ann Zorkova, and Denis E. Bragin
isualization of Intracranial Pressure Insults After Severe Traumatic V Brain Injury: Influence of Individualized Limits of Reactivity���������������������� 7 Joseph Donnelly, Frederick A. Zeiler, Fabian Güiza, Erta Beqiri, Simon J. Mitchell, Marcel J. Aries, Marek Czosnyka, and Peter Smielewski
I mpacts of a Pressure Challenge on Cerebral Critical Closing Pressure and Effective Cerebral Perfusion Pressure in Patients with Traumatic Brain Injury������������������������������������������������������������������������������������������ 11 Leandro Moraes, Bernardo Yelicich, Mayda Noble, Alberto Biestro, and Corina Puppo
emi-automated Computed Tomography Volumetry as a Proxy S for Intracranial Pressure in Patients with Severe Traumatic Brain Injury: Clinical Feasibility Study�������������������������������������������������������������������������������� 17 Ilse H. van de Wijgert, Jacobus F. A. Jansen, Jeanette Tas, Fred A. Zeiler, Paulien H. M. Voorter, Vera H. J. van Hal, and Marcel J. Aries
rrors and Consequences of Inaccurate Estimation of Mean E Blood Flow Velocity in Cerebral Arteries���������������������������������������������������������������� 23 Andras Czigler, Marta Fedriga, Erta Beqiri, Afroditi D. Lalou, Leanne A. Calviello, Manuel Cabeleira, Peter Toth, Peter Smielewski, and Marek Czosnyka
nalysis of the Association Between Lung Function and Brain A Tissue Oxygen Tension in Severe Traumatic Brain Injury ������������������������������ 27 Shadnaz Asgari, Chiara Robba, Erta Beqiri, Joseph Donnelly, Amit Gupta, Rafael Badenes, Mypinder Sekhon, Peter J. Hutchinson, Paolo Pelosi, and Arun Gupta
omparison of Two Intracranial Pressure Calculation Methods C and Their Effects on the Mean Intracranial Pressure and Intracranial Pressure Dose�������������������������������������������������������������������������������������������� 31 Ka Hing Chu, Erta Beqiri, Marek Czosnyka, and Peter Smielewski
vii
viii
xternal Hydrocephalus After Traumatic Brain Injury: E Retrospective Study of 102 Patients������������������������������������������������������������������������ 35 Laurent Gergelé, Romain Manet, A. Kolias, Marek Czosnyka, A. Lalou, Peter Smielewski, Peter J. Hutchinson, and Zofia H. Czosnyka
nalysis of Cardio-Cerebral Crosstalk Events in an Adult Cohort A from the CENTER-TBI Study������������������������������������������������������������������������������������������ 39 Giovanna Maria Dimitri, Erta Beqiri, Marek Czosnyka, Ari Ercole, Peter Smielewski, Pietro Lio, and CENTER-TBI High Resolution Substudy Participants and Investigators
erebrovascular Consequences of Elevated Intracranial Pressure C After Traumatic Brain Injury���������������������������������������������������������������������������������������� 43 Leanne Alexis Calviello, Frederick A. Zeiler, Joseph Donnelly, András Czigler, Andrea Lavinio, Peter J. Hutchinson, Marek Czosnyka, and Peter Smielewski
Part II Neuromonitoring and Management in Adult Nontraumatic Brain Injury ssessment of Cerebral Autoregulation in the Perifocal Zone A of a Chronic Subdural Hematoma ���������������������������������������������������������������������������� 51 Svetlana Trofimova, Alex Trofimov, Antony Dubrovin, Darya Agarkova, Ksenia Trofimova, Michael Dobrzeniecki, Ann Zorkova, and Denis E. Bragin
oninvasive Intracranial Pressure Monitoring in Chronic N Stroke Patients with Sedentary Behavior: A Pilot Study�������������������������������� 55 Gabriela Nagai Ocamoto, Deusdedit Lineu Spavieri Junior, Jean Alex Matos Ribeiro, Gustavo Henrique Frigieri Vilela, Aparecida Maria Catai, and Thiago Luiz Russo
se of Clustering to Investigate Changes in Intracranial Pressure U Waveform Morphology in Patients with Ventriculitis�������������������������������������� 59 Murad Megjhani, Kalijah Terilli, Aaron Kaplan, Brendan K. Wallace, Ayham Alkhachroum, Xiao Hu, and Soojin Park
erioperative Dynamics of Intracranial B-waves of Blood Flow P Velocity in the Basal Cerebral Arteries in Patients with Brain Arteriovenous Malformation �������������������������������������������������������������������������������������� 63 Vladimir Semenyutin, Vugar Aliev, Grigory Panuntsev, and Andreas Patzak
Part III Neuromonitoring and Management in Adult Mixed Brain Injury Populations ffects of Hyperthermia on Intracranial Pressure and Cerebral E Autoregulation in Patients with an Acute Brain Injury������������������������������������ 71 Andrey Oshorov, Anastasya Baranich, Alexander Polupan, Alexander Sychev, Ivan Savin, and Alexander Potapov
Comparative Study of the Effects of Early Versus Late A Cranioplasty on Cognitive Function������������������������������������������������������������������������ 75 Carla B. Rynkowski, Chiara Robba, Ricardo Vigolo de Oliveira, Rodrigo Fabretti, Thais Malickovski Rodrigues, Angelos G. Kolias, Guilherme Finger, Marek Czosnyka, and Marino Muxfeldt Bianchin
Contents
Contents
ix
ffects of Cranioplasty After Decompressive Craniectomy on E Neurological Function and Cerebral Hemodynamics in Traumatic Versus Nontraumatic Brain Injury ���������������������������������������������������������������������������� 79 Carla B. Rynkowski, Chiara Robba, Melina Loreto, Ana Carolina Wickert Theisen, Angelos G. Kolias, Guilherme Finger, Marek Czosnyka, and Marino Muxfeldt Bianchin
rain Multimodal Monitoring in Severe Acute Brain Injury: B Is It Relevant to Patient Outcome and Mortality?���������������������������������������������� 83 Elisabete Monteiro, António Ferreira, Edite Mendes, Cláudia Camila Dias, Marek Czosnyka, José Artur Paiva, and Celeste Dias
ong-Term Outcome After Decompressive Craniectomy L in a Developing Country������������������������������������������������������������������������������������������������ 87 Carla B. Rynkowski, Luciano Silveira Basso, Angelos G. Kolias, and Marino Muxfeldt Bianchin
Predictors of Successful Extubation in Neurocritical Care Patients���������� 91 Walter Videtta, Jeanette Vallejos, Gisela Roda, Hugo Collazos, Nico Naccarelli, Alex Tamayo, Noelia Calderón, Ariadna Bairaclioti, Martín Yoshida, Gabriel Vandaele, Ruth Toloza, Juan Quartino, Pablo Dunne, Maria G. Rodríguez, Marcos A. Teheran Wilches, Jhimmy J. Morales Vasquez, Brenda L. Fernandez Fernandez, and On Behalf of the Merlo ICU Research Group
Part IV Neuromonitoring and Management in the Pediatric Population I mpaired Autoregulation Following Resuscitation Correlates with Outcome in Pediatric Patients: A Pilot Study�������������������������������������������� 97 Julian Zipfel, Konstantin L. Hockel, Ines Gerbig, Ellen Heimberg, Martin U. Schuhmann, and Felix Neunhoeffer
rain Biomarkers in Children After Mild and Severe B Traumatic Brain Injury����������������������������������������������������������������������������������������������������103 Elena G. Sorokina, Zhanna B. Semenova, Valentin P. Reutov, Elena N. Arsenieva, Olga V. Karaseva, Andrey P. Fisenko, Leonid M. Roshal, and Vsevolod G. Pinelis
ecompressive Craniectomy for Traumatic Intracranial D Hypertension in Children����������������������������������������������������������������������������������������������109 Zhanna B. Semenova, Semen Meshcheryakov, Valery Lukyanov, and Sergey Arsenyev
se of Direct Intracranial Pressure and Brain Tissue Oxygen U Monitoring in Perioperative Management of Patients with Moyamoya Disease����������������������������������������������������������������������������������������������������������115 Maya Kommer, Michael Canty, Emer Campbell, Meharpal Sangra, Anthony Amato-Watkins, Simon Young, Christopher Hawthorne, Laura Moss, Ian Piper, Martin Shaw, and Roddy O’Kane
Part V Neuromonitoring Technology ariability of the Optic Nerve Sheath Diameter on the Basis V of Sex and Age in a Cohort of Healthy Volunteers ��������������������������������������������121 Karthikka Chandrapatham, Danilo Cardim, Marek Czosnyka, Alessandro Bertuccio, Anna Di Noto, Francesco Corradi, Joseph Donnelly, Paolo Pelosi, Peter J. Hutchinson, and Chiara Robba
x
Noninvasive Method for Monitoring Intracranial Pressure A During Postural Changes����������������������������������������������������������������������������������������������125 Michele L. Pierro, Nikole M. Shooshan, Saukhyda Deshmukh, and Gordon B. Hirschman
rterial and Venous Cerebral Blood Flow Velocities A in Healthy Volunteers������������������������������������������������������������������������������������������������������131 Karthikka Chandrapatham, Danilo Cardim, Francesco Corradi, Mypinder Sekhon, Donald Griesdale, Marek Czosnyka, and Chiara Robba
omparison of Waveforms Between Noninvasive and Invasive C Monitoring of Intracranial Pressure ������������������������������������������������������������������������135 Inês Gomes, Juliana Shibaki, Bruno Padua, Felipe Silva, Thauan Gonçalves, Deusdedit L. Spavieri-Junior, Gustavo Frigieri, Sérgio Mascarenhas, and Celeste Dias
Part VI Cerebrovascular Autoregulation in Acute Brain Injury and Cardiac Surgery n Update on the COGiTATE Phase II Study: Feasibility and A Safety of Targeting an Optimal Cerebral Perfusion Pressure as a Patient-Tailored Therapy in Severe Traumatic Brain Injury������������������������143 Jeanette Tas, Erta Beqiri, C. R. van Kaam, Ari Ercole, Gert Bellen, D. Bruyninckx, Manuel Cabeleira, Marek Czosnyka, Bart Depreitere, Joseph Donnelly, Marta Fedriga, Peter J. Hutchinson, D. Menon, Geert Meyfroidt, Annalisa Liberti, J. G. Outtrim, C. Robba, C. W. E. Hoedemaekers, Peter Smielewski, and Marcel J. Aries
uick Assessment of the Lower Limit of Autoregulation by Use of Q Transcranial Doppler Ultrasound During Cardiac Surgery����������������������������149 Laurent Gergelé, Younes Khadraoui, Romain Manet, and Olivier Desebbe
I nfluence of Patient Demographics on Optimal Cerebral Perfusion Pressure Following Traumatic Brain Injury ����������������������������������������������������������153 Jennifer Young, Laura Moss, Martin Shaw, Elizabeth Cahya, Maya Kommer, and Christopher Hawthorne
econdary Cerebral Ischemia at Traumatic Brain Injury Is More S Closely Related to Cerebrovascular Reactivity Impairment than to Intracranial Hypertension���������������������������������������������������������������������������������������159 Michael Dobrzeniecki, Alex Trofimov, Dmitry Martynov, Darya Agarkova, Ksenia Trofimova, Zhanna B. Semenova, and Denis E. Bragin
sability of Noninvasive Counterparts of Traditional U Autoregulation Indices in Traumatic Brain Injury����������������������������������������������163 Andras Czigler, Leanne A. Calviello, Frederick A. Zeiler, Peter Toth, Peter Smielewski, and Marek Czosnyka
atient’s Clinical Presentation and CPPopt Availability: P Any Association?����������������������������������������������������������������������������������������������������������������167 Annalisa Liberti, Erta Beqiri, Ari Ercole, Manuel Cabeleira, Jeanette Tas, Frederick A. Zeiler, Marek Czosnyka, Peter Smielewski, Marcel J. Aries, and CENTER-TBI High Resolution Substudy Participants and Investigators
Contents
Contents
xi
Optimal Cerebral Perfusion Pressure Based on Intracranial Pressure-Derived Indices of Cerebrovascular Reactivity: Which One Is Better for Outcome Prediction in Moderate/Severe Traumatic Brain Injury?��������������������������������������������������������������������������������������������������173 Alexander Lilja-Cyron, Frederick A. Zeiler, Erta Beqiri, Manuel Cabeleira, Peter Smielewski, and Marek Czosnyka
ptimal Cerebral Perfusion Pressure Assessed with a O Multi-Window Weighted Approach Adapted for Prospective Use: A Validation Study��������������������������������������������������������������������������������������������������181 Erta Beqiri, Ari Ercole, Marcel J. Aries, Manuel Cabeleira, Andras Czigler, Annalisa Liberti, Jeanette Tas, Joseph Donnelly, Xiuyun Liu, Marta Fedriga, Ka Hing Chu, Frederick A. Zeiler, Marek Czosnyka, and Peter Smielewski
onitoring of Cerebrovascular Reactivity in Intracerebral M Hemorrhage and Its Relation with Survival����������������������������������������������������������187 Ana V. Ferreira, Isabel Maia, and Celeste Dias
Part VII Neuroinformatics and Artificial Intelligence pectral Cerebral Blood Volume Accounting for Noninvasive S Estimation of Changes in Cerebral Perfusion Pressure in Patients with Traumatic Brain Injury������������������������������������������������������������������������������������������193 Danilo Cardim, Peter Smielewski, and Marek Czosnyka
mpirical Mode Decomposition-Based Method for Artefact E Removal in Raw Intracranial Pressure Signals����������������������������������������������������201 Isabel Martinez-Tejada, Jens E. Wilhjelm, Marianne Juhler, and Morten Andresen
AQ: A Noise-Resistant Calibration-Independent Compliance R Surrogate������������������������������������������������������������������������������������������������������������������������������207 Andreas Spiegelberg, Matthias Krause, Juergen Meixensberger, and Vartan Kurtcuoglu
ethodological Consideration on Monitoring Refractory Intracranial M Hypertension and Autonomic Nervous System Activity��������������������������������211 Marta Fedriga, András Czigler, Nathalie Nasr, Frederick A. Zeiler, Erta Beqiri, Stefan Wolf, Shirin K. Frisvolf, Peter Smielewski, and Marek Czosnyka
valuation of Software for Automated Measurement of E Adherence to ICP-Monitoring Threshold Guideline������������������������������������������217 Anthony Stell, Laura Moss, Christopher Hawthorne, Roddy O’Kane, Maya Kommer, Martin Shaw, and Ian Piper
ime Series Analysis and Prediction of Intracranial Pressure T Using Time-Varying Dynamic Linear Models ������������������������������������������������������225 Martin Shaw, Chris Hawthorne, Laura Moss, Maya Kommer, Roddy O’Kane, Ian Piper, and On Behalf of the BrainIT Group
utomatic Pulse Classification for Artefact Removal Using A SAX Strings, a CENTER-TBI Study ������������������������������������������������������������������������������231 Manuel Cabeleira, Marta Fedriga, and Peter Smielewski
xii
eepClean: Self-Supervised Artefact Rejection for Intensive Care D Waveform Data Using Deep Generative Learning ��������������������������������������������235 Tom Edinburgh, Peter Smielewski, Marek Czosnyka, Manuel Cabeleira, Stephen J. Eglen, and Ari Ercole
omparison of Two Algorithms Analysing the Intracranial C Pressure Curve in Terms of the Accuracy of Their Start-Point Detection and Resistance to Artefacts��������������������������������������������������������������������243 Anna-Li Schönenberg-Tu, Benjamin Pätzold, Adam Lichota, Christa Raak, Ghaith Al Assali, Friedrich Edelhäuser, Dirk Cysarz, Martin Marsch, and Wolfram Scharbrodt
lateau Waves of Intracranial Pressure: Methods for Automatic P Detection and Prediction����������������������������������������������������������������������������������������������249 Sofia Moreira, Maria Celeste Dias, and Miguel Velhote Correia
ython-Embedded Plugin Implementation in ICM+: Novel P Tools for Neuromonitoring Time Series Analysis with Examples Using CENTER-TBI Datasets������������������������������������������������������������������������������������������255 Michał M. Placek, Abdelhakim Khellaf, Benjamin L. Thiemann, Manuel Cabeleira, and Peter Smielewski
Part VIII Laboratory and Translational Research hysical Model for Investigating Intracranial Pressure with Clinical P Pressure Sensors and Diagnostic Ultrasound: Preliminary Results����������263 Rikke von Barm, Isabel Martinez Tejada, Marianne Juhler, Morten Andresen, and Jens E. Wilhjelm
ugmented Reality-Assisted Neurosurgical Drain Placement A (ARANED): Technical Note ��������������������������������������������������������������������������������������������267 Frederick Van Gestel, Taylor Frantz, Mumtaz Hussain Soomro, Shirley A. Elprama, Cedric Vannerom, An Jacobs, Jef Vandemeulebroucke, Bart Jansen, Thierry Scheerlinck, and Johnny Duerinck
ower Limit of Reactivity Assessed with PRx in an Experimental L Setting������������������������������������������������������������������������������������������������������������������������������������275 Erta Beqiri, Ken M. Brady, Jennifer K. Lee, Joseph Donnelly, Frederick A. Zeiler, Marek Czosnyka, and Peter Smielewski
nalysis of Intracranial Pressure Pulse–Pressure Relationship: A Experimental Validation������������������������������������������������������������������������������������������������279 Katarzyna Kaczmarska, Piotr Śmielewski, Magdalena Kasprowicz, Agnieszka Kazimierska, Antoni Grzanka, Zofia H. Czosnyka, and Marek Czosnyka
erebrovascular Impedance During Hemodynamic Change C in Rabbits: A Pilot Study������������������������������������������������������������������������������������������������283 Agnieszka Kazimierska, Magdalena Kasprowicz, Michał M. Placek, and Marek Czosnyka
Contents
Contents
xiii
I mproved Cerebral Perfusion Pressure and Microcirculation by Drag Reducing Polymer-Enforced Resuscitation Fluid After Traumatic Brain Injury and Hemorrhagic Shock������������������������������������������������289 Denis E. Bragin, Olga A. Bragina, Alex Trofimov, Lucy Berliba, Marina V. Kameneva, and Edwin M. Nemoto
ritical Closing Pressure by Diffuse Correlation Spectroscopy C in a Neonatal Piglet Model��������������������������������������������������������������������������������������������295 Leah I. Elizondo, Eric L. Vu, Kathleen K. Kibler, Danielle R. Rios, R. Blaine Easley, Dean Andropoulos, Sebastian Acosta, Craig Rusin, Kenneth Brady, and Christopher J. Rhee
Part IX Hydrocephalus and Cerebrospinal Fluid Biophysics iffusion and Flow MR Imaging to Investigate Hydrocephalus D Patients Before and After Endoscopic Third Ventriculostomy ��������������������303 Olivier Balédent, Cyrille Capel, Serge Metanbou, and Roger Bouzerar
ower Breakpoint of Intracranial Amplitude-Pressure L Relationship in Normal Pressure Hydrocephalus����������������������������������������������307 Zofia H. Czosnyka, Afroditi D. Lalou, Eva Nabbanja, Matthew Garnett, Nicole C. Keong, Eric A. Schmidt, D. J. Kim, and Marek Czosnyka
Single Center Experience in Cerebrospinal Fluid Dynamics Testing ��������311 Zofia H. Czosnyka, Marek Czosnyka, Piotr Smielewski, Afroditi D. Lalou, Eva Nabbanja, Matthew Garnett, Slawomir Barszcz, Eric A. Schmidt, Shahan Momjian, Magda Kasprowicz, Gianpaolo Petrella, Brian Owler, Nicole C. Keong, Peter J. Hutchinson, and John D. Pickard
hy Hydrocephalus Patients Suffer When the Weather W Changes: A New Hypothesis����������������������������������������������������������������������������������������315 Andreas Spiegelberg, Lennart Stieglitz, and Vartan Kurtcuoglu
ranscranial Doppler Plateau Wave in a Patient with Pseudo-Chiari T Malformation����������������������������������������������������������������������������������������������������������������������319 Leandro Moraes, Mayda Noble, Bernardo Yelicich, Federico Salle, Karina DiCienzo, Alberto Biestro, and Corina Puppo
elemetric Intracranial Pressure: A Snapshot Does not Give T the Full Story ����������������������������������������������������������������������������������������������������������������������323 Maya Kommer, Richard G. Boulton, Lynette Loi, Sophie Robinson, Christopher Hawthorne, Martin Shaw, Ian Piper, Laura Moss, Anthony Amato-Watkins, Emer Campbell, Meharpal Sangra, and Roddy O’Kane
oninvasive Intracranial Pressure Assessment in Patients N with Suspected Idiopathic Intracranial Hypertension������������������������������������325 Bernhard Schmidt, Marek Czosnyka, Danilo Cardim, and Bernhard Rosengarten
hould the Impact of Postural Change of Intracranial Pressure S After Surgical Repair of Skull Base Cerebrospinal Fluid Leaks Be Considered? A Preliminary Survey ��������������������������������������������������������������������329 Valentin Favier, Louis Crampette, Laurent Gergelé, Generoso De Cristofaro, Emmanuel Jouanneau, and Romain Manet
xiv
ssessment of Pressure-Volume Index During Lumbar Infusion A Study: What Is the Optimal Method? ����������������������������������������������������������������������335 Alexandra Vallet, Laurent Gergelé, Emmanuel Jouanneau, Eric A. Schmidt, and Romain Manet
ostural Regulation of Intracranial Pressure: A Critical Review P of the Literature ����������������������������������������������������������������������������������������������������������������339 Laurent Gergelé and Romain Manet
ifferences in Cerebrospinal Fluid Dynamics in Posttraumatic D Hydrocephalus Versus Atrophy, Including Effect of Decompression and Cranioplasty ��������������������������������������������������������������������������������������������������������������343 Virginia Levrini, Afroditi D. Lalou, Zofia H. Czosnyka, Angelos G. Kolias, Laurent Gergelé, Matthew Garnett, Peter J. Hutchinson, and Marek Czosnyka
lobal Cerebral Autoregulation, Resistance to Cerebrospinal Fluid G Outflow and Cerebrovascular Burden in Normal Pressure Hydrocephalus ������������������������������������������������������������������������������������������������������������������349 Afroditi D. Lalou, Shadnaz Asgari, Matthew Garnett, Eva Nabbanja, Marek Czosnyka, and Zofia H. Czosnyka
omparison of Assessment for Shunting with Infusion C Studies Versus Extended Lumbar Drainage in Suspected Normal Pressure Hydrocephalus�������������������������������������������������������������������������������355 Virginia Levrini, Matthew Garnett, Eva Nabbanja, Marek Czosnyka, Zofia H. Czosnyka, and Afroditi D. Lalou
he Role of Cerebrospinal Fluid Dynamics in Normal Pressure T Hydrocephalus Diagnosis and Shunt Prognostication������������������������������������359 Afroditi D. Lalou, Shadnaz Asgari, Marek Czosnyka, Eva Nabbanja, Matthew Garnett, and Zofia H. Czosnyka
Part X Spinal Cord Injury afety and Feasibility of Lumbar Cerebrospinal Fluid Pressure S and Intraspinal Pressure Studies in Cervical Stenosis: A Case Series������������������������������������������������������������������������������������������������������������������������367 Carl Moritz Zipser, José Miguel Spirig, José Aguirre, Anna-Sophie Hofer, Nikolai Pfender, Markus Hupp, Armin Curt, Mazda Farshad, and Martin Schubert
orrection to: Comparison of Two Algorithms Analysing the C Intracranial Pressure Curve in Terms of the Accuracy of Their Start-Point Detection and Resistance to Artefacts����������������������������������������������C1 Anna-Li Schönenberg-Tu, Benjamin Pätzold, Adam Lichota, Christa Raak, Ghaith Al Assali, Friedrich Edelhäuser, Dirk Cysarz, Martin Marsch, and Wolfram Scharbrodt
orrection to: Why Hydrocephalus Patients Suffer When the Weather C Changes: A New Hypothesis������������������������������������������������������������������������������������������C3 Andreas Spiegelberg, Lennart Stieglitz, and Vartan Kurtcuoglu
Contents
Part I Neuromonitoring and Management in Adult Traumatic Brain Injury
Microcirculatory Biomarkers of Secondary Cerebral Ischemia in Traumatic Brain Injury Alex Trofimov, Antony Dubrovin, Dmitry Martynov, Darya Agarkova, Ksenia Trofimova, Ann Zorkova, and Denis E. Bragin
Introduction
Severity Score (ISS) greater than 60. All patients were subjected to multiphase PCT using a 64-slice Philips Ingenuity CT tomograph (Philips Medical Systems, Cleveland, OH, Secondary cerebral ischemia (SCI) is still one of the leading USA). PCT was performed 1–4 days after TBI (mean causes of mortality and disability in patients who have expe3.3 ± 0.5 days). The perfusion examination report included rienced a traumatic brain injury (TBI) [1]; however, changes initial contrast-free CT of the brain. Further extended scanning in microcirculation parameters that occur with posttraumatic with a contrast agent was performed within 60 s, focusing on SCI still remain underinvestigated [2]. The purpose of this 16 areas of interest, 160 mm in thickness. The scanning work was to study changes in cerebral microcirculation parameters were 160 kVp, 160 mA, 70 mAs, 512 × 512. The parameters in the development of SCI. contrast agent Ultravist 370 (Schering, Berlin, Germany) was administered, using a syringe injector (Medrad Stellant, Bayer HealthCare, Whippany, NJ, USA), into a peripheral vein Materials and Methods through a standard 20 G catheter at a rate of 4–5 mL/s in a dose of 30–50 mL per examination. After the scanning, the This retrospective, observational, nonrandomized, single- data were transferred to a KIR picture-archiving and commucenter study was conducted as an analysis of a prospectively nication system (PACS) (JSC, Kazan, Russia) and a Philips maintained database cohort (2013–2018) and included patients Extended Brilliance Workspace workstation (Philips with a head injury and unilateral foci of posttraumatic isch- HealthCare, Amsterdam, the Netherlands) with MATLAB emia. The protocol of the study was reviewed and approved by 2013b (The MathWorks, Natick, MA, USA). Artery and vein the institutional ethics committee, and conformed to the stan- marks were automatically recorded, followed by manual condards of the Declaration of Helsinki. Neuromonitoring param- trol of indices in the time–concentration diagram. The region eters were measured as part of standard patient care, and the of interest was established on the basis of subcortical areas of data were archived in a physiological monitoring database. the middle cerebral artery (MCA). Errors introduced by delay Age, sex, injury severity, and clinical condition data were and dispersion of the contrast bolus before arrival in the cererecorded in this database at the time of monitoring. The study bral circulation were corrected by use of a block-circulant inclusion criteria were as follows: moderate or severe TBI deconvolution algorithm. Quantitative perfusion indices, within 6 h after head injury, with a Glasgow Coma Scale including cerebral blood flow (CBF), were calculated on a (GCS) score ≤ 12, and unilateral foci of posttraumatic isch- voxel-wise basis and were used to generate color-coded maps. emia on perfusion computed tomography (PCT). We excluded Voxels with CBF >100 mL/100 g/min or cerebral blood volpatients who were younger than 16 years or had an Injury ume (CBV) >8 mL/100 g were assumed to contain vessels and removed from the perfusion map [3]. Core infarction on PCT was defined as CBV 38% in comparison with the contralateral hemisphere K. Trofimova · A. Zorkova Department of Neurosurgery, Privolzhsky Research Medical [4]. Immediately after PCT, Doppler ultrasound of the MCA University, Nizhniy Novgorod, Russia was recorded bilaterally with 2 MHz probes (Sonomed 300 M, D. E. Bragin Spektromed, Moscow, Russia). A Centaurus 2.0 neuromonitor Lovelace Biomedical Research Institute, Albuquerque, NM, USA (Privolzhsky State Medical University, Nizhny Novgorod, Department of Neurosurgery, University of New Mexico School of Russia) was used to monitor the cerebral complex during the Medicine, Albuquerque, NM, USA B. Depreitere et al. (eds.), Intracranial Pressure and Neuromonitoring XVII, Acta Neurochirurgica Supplement 131, https://doi.org/10.1007/978-3-030-59436-7_1, © Springer Nature Switzerland AG 2021
3
4
A. Trofimov et al.
study. Arterial blood pressure and its amplitude (MAPamp) were measured noninvasively using a Cardex MAP-03 monitor (Cardex, Nizhny Novgorod, Russia). The cerebrovascular resistance (CVR), cerebral arterial compliance (CAC), cerebrovascular time constant (CTC), and critical closing pressure (CCP) were measured using a complex neuromonitoring, as described previously [5, 6].
Statistical Analysis To determine whether the data were normally distributed, a Shapiro–Wilk test was used. The data were expressed as mean ± standard deviation. A statistical analysis of all results was performed using a paired Student’s t test. To specify the structure of the relationship of the variables, factor analysis was performed. We used a two-factor model with a raw varimax rotation. P values 25 cm3
24
11.9
III
Swelling
28
12.7
IV
Shift
37
16.8
V
Evacuated mass lesion
113
51.4
VI
Nonevacuated mass lesion
0
0
values were significantly higher than normal reference values (P