Environmental Epigenomics in Health and Disease: Epigenetics and Complex Diseases [1 ed.] 978-3-642-36826-4, 978-3-642-36827-1
There are now compelling human epidemiological and animal experimental data that indicate the risk of developing adult-o
189 13 40KB
English Pages 339 [341] Year 2013
Table of contents :
Front Matter....Pages i-xiv
Front Matter....Pages 1-1
Epigenetics and Maternal Brain Evolution....Pages 3-20
Social Environment and DNA Methylation: A Mechanism for Linking Nurture and Nature....Pages 21-35
Sex Differences in Epigenetic Programming of Brain Differentiation: Implications for Mental Health and Disease....Pages 37-54
Front Matter....Pages 55-55
Phenotypic Plasticity, Pleiotropy, and the Growth-First Theory of Imprinting....Pages 57-72
The Imprinted Brain: How Genes Set the Balance Between Autism and Psychosis....Pages 73-96
Epigenetics at the Interface of Genetics and Environmental Factors in Autism....Pages 97-114
Epigenomic and Noncoding RNA Regulation in Addictive Processes....Pages 115-165
Epigenetic Therapies in Neurological Diseases....Pages 167-193
Front Matter....Pages 195-195
Nutrition, Histone Epigenetic Marks, and Disease....Pages 197-217
Chromatin Switching and Gene Dynamics Associated with Type 2 Diabetes....Pages 219-233
Developmental Epigenetic Programming in Diabetes and Obesity....Pages 235-253
Front Matter....Pages 255-255
Developmental Reprogramming by Environmental Estrogens: How Early Life Exposures Affect Cancer Risk in Adulthood....Pages 257-267
Human Cancer Epigenetics....Pages 269-293
Front Matter....Pages 295-295
Legal and Ethical Implications of Epigenetics....Pages 297-308
Back Matter....Pages 309-339
Front Matter....Pages i-xiv
Front Matter....Pages 1-1
Epigenetics and Maternal Brain Evolution....Pages 3-20
Social Environment and DNA Methylation: A Mechanism for Linking Nurture and Nature....Pages 21-35
Sex Differences in Epigenetic Programming of Brain Differentiation: Implications for Mental Health and Disease....Pages 37-54
Front Matter....Pages 55-55
Phenotypic Plasticity, Pleiotropy, and the Growth-First Theory of Imprinting....Pages 57-72
The Imprinted Brain: How Genes Set the Balance Between Autism and Psychosis....Pages 73-96
Epigenetics at the Interface of Genetics and Environmental Factors in Autism....Pages 97-114
Epigenomic and Noncoding RNA Regulation in Addictive Processes....Pages 115-165
Epigenetic Therapies in Neurological Diseases....Pages 167-193
Front Matter....Pages 195-195
Nutrition, Histone Epigenetic Marks, and Disease....Pages 197-217
Chromatin Switching and Gene Dynamics Associated with Type 2 Diabetes....Pages 219-233
Developmental Epigenetic Programming in Diabetes and Obesity....Pages 235-253
Front Matter....Pages 255-255
Developmental Reprogramming by Environmental Estrogens: How Early Life Exposures Affect Cancer Risk in Adulthood....Pages 257-267
Human Cancer Epigenetics....Pages 269-293
Front Matter....Pages 295-295
Legal and Ethical Implications of Epigenetics....Pages 297-308
Back Matter....Pages 309-339
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