Harper's Illustrated Biochemistry, 28th Edition (LANGE Basic Science) [28 ed.]
0071625917, 9780071625913
The biochemistry text that every medical student must own--now in full color! Comprehensive, concise, and up-to-date, Ha
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11MB
English
Pages 704
Year 2009
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Table of contents :
Contents......Page 6
Preface......Page 10
1. Biochemistry & Medicine......Page 12
2. Water & pH......Page 17
3. Amino Acids & Peptides......Page 25
4. Proteins: Determination of Primary Structure......Page 32
5. Proteins: Higher Orders of Structure......Page 42
6. Proteins: Myoglobin & Hemoglobin......Page 54
7. Enzymes: Mechanism of Action......Page 62
8. Enzymes: Kinetics......Page 73
9. Enzymes: Regulation of Activities......Page 86
10. Bioinformatics & Computational Biology......Page 95
11. Bioenergetics: The Role of ATP......Page 103
12. Biologic Oxidation......Page 109
13. The Respiratory Chain & Oxidative Phosphorylation......Page 114
14. Carbohydrates of Physiologic Significance......Page 124
15. Lipids of Physiologic Significance......Page 132
16. Overview of Metabolism & the Provision of Metabolic Fuels......Page 142
17. The Citric Acid Cycle: The Catabolism of Acetyl-CoA......Page 154
18. Glycolysis & the Oxidation of Pyruvate......Page 160
19. Metabolism of Glycogen......Page 168
20. Gluconeogenesis & the Control of Blood Glucose......Page 176
21. The Pentose Phosphate Pathway & Other Pathways of Hexose Metabolism......Page 185
22. Oxidation of Fatty Acids: Ketogenesis......Page 195
23. Biosynthesis of Fatty Acids & Eicosanoids......Page 204
24. Metabolism of Acylglycerols & Sphingolipids......Page 216
25. Lipid Transport & Storage......Page 223
26. Cholesterol Synthesis, Transport, & Excretion......Page 235
27. Biosynthesis of the Nutritionally Nonessential Amino Acids......Page 245
28. Catabolism of Proteins & of Amino Acid Nitrogen......Page 250
29. Catabolism of the Carbon Skeletons of Amino Acids......Page 259
30. Conversion of Amino Acids to Specialized Products......Page 273
31. Porphyrins & Bile Pigments......Page 282
32. Nucleotides......Page 296
33. Metabolism of Purine & Pyrimidine Nucleotides......Page 303
34. Nucleic Acid Structure & Function......Page 313
35. DNA Organization, Replication, & Repair......Page 323
36. RNA Synthesis, Processing, & Modification......Page 346
37. Protein Synthesis & the Genetic Code......Page 364
38. Regulation of Gene Expression......Page 380
39. Molecular Genetics, Recombinant DNA, & Genomic Technology......Page 399
40. Membranes: Structure & Function......Page 417
41. The Diversity of the Endocrine System......Page 436
42. Hormone Action & Signal Transduction......Page 455
43. Nutrition, Digestion, & Absorption......Page 470
44. Micronutrients: Vitamins & Minerals......Page 478
45. Free Radicals and Antioxidant Nutrients......Page 493
46. Intracellular Traffic & Sorting of Proteins......Page 498
47. Glycoproteins......Page 517
48. The Extracellular Matrix......Page 538
49. Muscle & the Cytoskeleton......Page 556
50. Plasma Proteins & Immunoglobulins......Page 577
51. Hemostasis & Thrombosis......Page 594
52. Red & White Blood Cells......Page 604
53. Metabolism of Xenobiotics......Page 620
54. Biochemical Case Histories......Page 627
Appendix I......Page 658
Appendix II......Page 659
A......Page 662
B......Page 666
C......Page 667
D......Page 671
E......Page 673
F......Page 675
G......Page 677
H......Page 680
I......Page 683
K......Page 684
L......Page 685
M......Page 686
N......Page 689
O......Page 690
P......Page 691
R......Page 696
S......Page 698
T......Page 700
V......Page 703
Z......Page 704