Genetics: From Genes to Genomes [3 ed.] 9780073227382, 0073227382
Genetics: From Genes to Genomes is a cutting-edge, introductory genetics text authored by an unparalleled author team, i
360 70 95MB
English Pages 917 Year 2006
Table of contents :
Preface......Page 1
Guided Tour......Page 5
1. Genetics: The Study of Biological Information......Page 13
2. Mendel’s Breakthrough: Patterns, Particles, and Principles of Heredity......Page 25
3. Extensions to Mendel: Complexities in Relating Genotype to Phenotype......Page 55
4. The Chromosome Theory of Inheritance......Page 88
5. Linkage, Recombination, and the Mapping of Genes on Chromosomes......Page 124
6. DNA: How the Molecule of Heredity Carries, Replicates, & Recombines Inform.......Page 166
7. Anatomy and Function of a Gene: Dissection Through Mutation......Page 202
8. Gene Expression: The Flow of Genetic Information from DNA via RNA to Protein......Page 248
9. Deconstructing the Genome: DNA at High Resolution......Page 287
10. Reconstructing the Genome Through Genetic and Molecular Analysis......Page 331
11. The Direct Detection of Genotype Distinguishes Individual Genomes......Page 381
12. The Eukaryotic Chromosome: An Organelle for Packaging and Managing DNA......Page 425
13. Chromosomal Rearrange. & Changes in Chromo. Number Reshape Eukaryotic Gen.......Page 450
14. The Prokaryotic Chromosome: Genetic Analysis in Bacteria......Page 496
15. The Chromo. of Organelle Outside the Nuc. Exhib. Non.Mendel. Patt. of Inher.......Page 534
16. Gene Regulation in Prokaryotes......Page 560
17. Gene Regulation in Eukaryotes......Page 590
18. Cell-Cycle Regulation and the Genetics of Cancer......Page 625
19. Using Genetics to Study Development......Page 657
20. The Genetic Analysis of Populations and How They Evolve......Page 684
21. Evolution at the Molecular Level......Page 713
A: Saccharomyces cerevisiae: Genetic Portrait of a Yeast......Page 745
B: Arabidopsis thaliana: Genetic Portrait of a Model Plant......Page 764
C: Caenorhabditis elegans: Genetic Port. of a Simple Multicell. Animal......Page 793
D: Drosophila melanogaster: Genetic Portrait of the Fruit Fly......Page 817
E: Mus musculus: Genetic Portrait of the House Mouse......Page 848
Guidelines for Gene Nomenclature......Page 869
Brief Answer Section......Page 870
Glossary......Page 882
Credits......Page 896
Index......Page 900
Preface......Page 1
Guided Tour......Page 5
1. Genetics: The Study of Biological Information......Page 13
2. Mendel’s Breakthrough: Patterns, Particles, and Principles of Heredity......Page 25
3. Extensions to Mendel: Complexities in Relating Genotype to Phenotype......Page 55
4. The Chromosome Theory of Inheritance......Page 88
5. Linkage, Recombination, and the Mapping of Genes on Chromosomes......Page 124
6. DNA: How the Molecule of Heredity Carries, Replicates, & Recombines Inform.......Page 166
7. Anatomy and Function of a Gene: Dissection Through Mutation......Page 202
8. Gene Expression: The Flow of Genetic Information from DNA via RNA to Protein......Page 248
9. Deconstructing the Genome: DNA at High Resolution......Page 287
10. Reconstructing the Genome Through Genetic and Molecular Analysis......Page 331
11. The Direct Detection of Genotype Distinguishes Individual Genomes......Page 381
12. The Eukaryotic Chromosome: An Organelle for Packaging and Managing DNA......Page 425
13. Chromosomal Rearrange. & Changes in Chromo. Number Reshape Eukaryotic Gen.......Page 450
14. The Prokaryotic Chromosome: Genetic Analysis in Bacteria......Page 496
15. The Chromo. of Organelle Outside the Nuc. Exhib. Non.Mendel. Patt. of Inher.......Page 534
16. Gene Regulation in Prokaryotes......Page 560
17. Gene Regulation in Eukaryotes......Page 590
18. Cell-Cycle Regulation and the Genetics of Cancer......Page 625
19. Using Genetics to Study Development......Page 657
20. The Genetic Analysis of Populations and How They Evolve......Page 684
21. Evolution at the Molecular Level......Page 713
A: Saccharomyces cerevisiae: Genetic Portrait of a Yeast......Page 745
B: Arabidopsis thaliana: Genetic Portrait of a Model Plant......Page 764
C: Caenorhabditis elegans: Genetic Port. of a Simple Multicell. Animal......Page 793
D: Drosophila melanogaster: Genetic Portrait of the Fruit Fly......Page 817
E: Mus musculus: Genetic Portrait of the House Mouse......Page 848
Guidelines for Gene Nomenclature......Page 869
Brief Answer Section......Page 870
Glossary......Page 882
Credits......Page 896
Index......Page 900
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