Table of contents : CONTENTS NEWS IN BRIEF News at a glance NEWS IN DEPTH India’s pandemic toll far exceeds official count Artificial intelligence unmasks anonymous chess players Mapping where HIV hides suggests cure strategy Indonesia’s research reform triggers layoffs and protests Omicron leads to fresh wave of meeting cancellations Study of soldiers implicates common virus as MS trigger FEATURE Cloning goes wild POLICY FORUM Legal obstacles to toxic chemical research PERSPECTIVES Quantum probe of space-time curvature Fetal bovine serum—a cell culture dilemma The scent of atherosclerosis Molten iron in Earth-like exoplanet cores A molecular view of human amyloid-β folds Inclusion in human–machine interactions BOOKS ET AL. An antiquated language, reimagined Who gets counted and how LETTERS Pakistan’s markhor population in decline Central nervous system weapons dealt a blow Transboundary conservation’s rise Technical comment abstracts RESEARCH IN BRIEF From Science and other journals REVIEW CDK4 and CDK6 kinases: From basic science to cancer therapy RESEARCH ARTICLES Mitochondria shed their outer membrane in response to infection-induced stress Impact of community masking on COVID-19: A cluster-randomized trial in Bangladesh 4′-Fluorouridine is an oral antiviral that blocks respiratory syncytial virus and SARS-CoV-2 replication Cryo-EM structures of amyloid-β 42 filaments from human brains Organic synthesis associated with serpentinization and carbonation on early Mars An RNA exosome subunit mediates cell-to-cell trafficking of a homeobox mRNA via plasmodesmata Heterologous infection and vaccination shapes immunity against SARS-CoV-2 variants REPORTS Distinguishing between non-abelian topological orders in a quantum Hall system Ultrahard magnetism from mixed-valence dilanthanide complexes with metal-metal bonding Measuring the melting curve of iron at super-Earth core conditions Crossover between strongly coupled and weakly coupled exciton superfluids The effects of defaunation on plants’ capacity to track climate change Olfactory receptor 2 in vascular macrophages drives atherosclerosis by NLRP3-dependent IL-1 production Bacterial gasdermins reveal an ancient mechanism of cell death Observation of a gravitational Aharonov-Bohm effect DEPARTMENTS Editorial Editorial Working Life Science Staff New Products Science Careers