Toxicogenomics and proteomics [1 ed.] 9781586034023, 1586034022

Table of contents :
Cover......Page 1
Title page......Page 2
Foreword......Page 6
Contents......Page 8
Systems Biology......Page 10
The Role of Bioinformatics in Toxicogenomics and Proteomics......Page 18
Interpretation of Global Gene Expression Data through Gene Ontologies......Page 34
Expanding the Information Window to Increase Proteomic Sensitivity and Selectivity......Page 42
Understanding the Significance of Genetic Variability in the Human PON1 Gene......Page 52
Functional Genomics Methods in Hepatotoxicity......Page 64
The Toxicogenomics of Low-level Exposure to Organophosphate Nerve Agents......Page 84
Molecular Biomarkers......Page 96
Expression Profiling of Sulfur Mustard Exposure in Murine Skin: Chemokines, Cytokines and Growth Factors......Page 118
Further Progress in DNA Repair Puzzle in the Postgenomics Era......Page 126
Non-Ribosomal Peptide Synthetases for the Production of Bioactive Peptides with Syringomycin Synthetase as an Example......Page 134
Bacterial Genomics and Measures for Controlling the Threat from Biological Weapons......Page 144
An Evaluation of Toxins and Bioregulators as Terrorism and Warfare Agents......Page 156
Prospects on Immunoassays for the Detection of Pesticides in the Environment......Page 168
Prospects for Holographic Optical Tweezers......Page 190
G......Page 212
P......Page 213
X......Page 214
Author Index......Page 216