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Discover the essential nutrient that will work wonders foryour health!
•
•
•
Alleviate muscle pain insomnia and a host of other conditions ,
,
Activate vital enzymes to increase your body's energy
Help to prevent serious illnesses such as depression and heart disease
V
More praise for The Miracle of Magnesium “Every doctor and patient should read
book on
many
this
comprehensive
magnesium. ... I loved this book. Clearly written and packed with information, it offers a compendium on natural medicine and is an invaluable resource for both practitioner and public alike. It is the most comprehensive and well-referenced guide to the myriad benefits of magnesium published to date.” Dr. Carolyn DeMarco Author of Take Charge of Your Body: Women's Health Advisor the
roles of
—
“Throughout this volume and with utmost clarity, Carolyn Dean presents invaluable recommendations based on the latest magnesium research. Virtually every American can benefit.” Paul Pitchford Author of Healing with Whole Foods: Asian Traditions and Modern Nutrition
—
“Physicians and therapists have paid scant attention to
very important element, which is also involved in maintaining our good health. The massive evidence is
this
book on magnesium. I am pleased have been taking magnesium for so many years.” Abram Hoffer, M.D. Author of Putting It All Together:
here in this important to
—
The
New
Orthomolecular Nutrition Please turn the page for
more
reviews.
.
.
.
“Excellent research together with valuable inspiration to empower the doctor within
each of us.”
—Joshua Rosenthal
Director of the Institute for Integrative Nutrition
Author of The Energy Balance Diet “An
enlightening and practical book. Dr.
Dean
supplies
powerful information for people while trumpeting a reminder to doctors about this essential and often overlooked mineral elixir. The Miracle of Magnesium should be required reading for living a rich, healthy life.” Eugene Charles, D.C., DIBAK
—
Author of Physician Heal Thy Patient and Becoming Healthy Wealthy and Wise ,
“I
have been in complementary medicine for thirty years
was to know about magnesium until I [read] the latest book by Dr. Carolyn Dean. This book is the most comprehensive review on the subject I have ever read. As one can expect from a physician with such vast and diversified knowledge, The Miracle of Magnesium contains information on allied fields of medicine that makes this book an incredible resource for doctors and patients alike. The Miracle of Magnesium is a book that is going to be of great service to humanity since, as the author points out, there is so much information on magnesium that has failed to be and
I
believed
—
I
knew
all
there
included in the medical curriculum.”
—Serafina Corsello, M.D.
Wellness Medical Center for Integrative Medicine Author of Ageless Healing
The Miracle of
Magnesium
CAROLYN DEAN,
M.D., N.D.
BALLANTINE BOOKS NEW YORK
\
A
Ballantine
Book
Published by The Ballantine Publishing Group
© 2003 by Carolyn Dean, M.D., N.D. Foreword copyright © 2003 by Dr. Bella Altura and Dr. Burton Altura Copyright
All rights reserved under International and
Pan-American Copyright Conventions. Published in the United States by The Ballantine Publishing Group, a division of Random House, Inc., New York, and simultaneously in Canada by Random House of Canada Limited, Toronto. Ballantine and colophon are registered trademarks
of
Random House,
Inc.
www.ballantinebooks.com Library of Congress Cataloging-in-Publication Data
Dean, Carolyn.
The miracle of magnesium
/
Carolyn Dean.
—
1st ed.
cm.
p.
Includes bibliographical references and index.
ISBN 1
.
Magnesium
0-343-44588-0
deficiency diseases.
2.
Magnesium
—Health
Title.
I.
RC627.M3 D43 2003 6 16.3 '96
—dc21
2002028159
Book
design by Holly Johnson
Cover design by Mike Stromberg Manufactured
in the
United States of America
First Edition:
13579
January 2003 10
8642
aspects.
To
the Miracle
Women in my life.
My mum, Rena, my three sisters: Chris (who labored with
me on
the
first drafts
Anne, and Evelyn. And
Thank you
of “the
my agent, all.
wee maggie”), Beth.
Digitized by the Internet Archive in
2016
https://archive.org/details/miracleofmagnesiOOdean
Contents
Foreword
ix
introduction
1
PART ONE: THE HISTORY OF MAGNESIUM 1
2
The Case
for
Magnesium: The Personal History
of an Element
13
Magnesium: The Missing Mineral
30
PART TWO: MAGNESIUM-DEFICIENT CONDITIONS Magnesium
3
Anxiety, Pain, and
4
Migraines, Strokes,
5
Hypertension, High Cholesterol, Spastic Heart,
Head
for Athletes
Injury,
and Brain Surgery
45 63
Angina, Arrhythmia, Arteriosclerosis, and
Heart Attack 6
Syndrome X, Diabetes, and Sugar Imbalance
81
110
Contents
7
PMS, Dysmenorrhea,
Infertility,
Polycystic
Ovarian Syndrome, Preeclampsia, and Cerebral
8
Palsy
122
Osteoporosis and Kidney Stones
139
PART THREE: THE RESEARCH CONTINUES 9
Chronic Fatigue Syndrome and Fibromyalgia
10
Environmental
11
Health and Longevity
Illness
and Asthma
155 171
190
PART FOUR: TESTING AND SUPPLEMENTS 12
Magnesium Requirements,
13
Supplementation and Homeopathics
Testing, and Sources
207 224
Appendix: Magnesium Content of Selected Foods
235
Resources
238
References
242
Index
271
viii
Foreword
“Clearly there
is
more
to
life
than magnesium”
is
one of the
.remarks from Dr. Dean’s remarkable, almost encyclopedic,
but very readable book. Her book
is
long overdue, for
gives the lay reader a chance to discover for
the
many
reasons
needs for
why
this
this has
it
him- or herself
mineral in a healthy
diet,
and the
not been emphasized in the everyday
literature.
The requirements
much
for
magnesium
neglected topic and this
in
our diet
book by Dr. Dean
is
indeed a
brings the
message home by her carefully written repetitive emphasis
on the
subject.
That does not mean that there are not many
other nutrients necessary in our daily food intake, as stated above, but the point she so clearly makes in general has not
is
that the public
been notified to look for the proper
Foreword
amount of this mineral sons magnesium
is
in the daily diet
needed
in
and of the many rea-
our bodies.
After a cursory overview of the material, the
book
should be read as one would read an encyclopedia, that pick out the parts one
is
go back and try to read gist
of
how
particularly interested in, and then
it all.
This
or she has been informed, be
“An ounce so
it is
way
the reader will get the
important magnesium really
zines, or the rest of the
a
it
is
and
how
little
he
from newspapers, maga-
news media. As the old adage worth
says,
in gold,”
and
balanced nutrition, which includes this
all-
of prevention
with
is
is
its
weight
important mineral in adequate amounts. (As to the other interesting parts of the book, our qualifications only allow us to
comment on
the material per-
taining to the scientific basis for the need of magnesium.)
Dr. Bella T. Altura
Research Professor of
Physiology and Pharmacology
SUNY Downstate Medical Brooklyn, New York Dr. Burton
Center
M. Altura
Professor of Physiology,
Pharmacology, and Medicine
SUNY Downstate Medical Brooklyn,
New York
Center
Introduction
From
2nd
the 74th Congress,
session, Senate
Document
no. 264:
Do you know from
that
most of us today
are suffering
certain dangerous diet deficiencies
not be remedied until depleted
soils
which can-
from which our
food comes are brought into proper mineral balance? The alarming fact bles
and grains)
acres of land that
now
is
that foods (fruits, vegeta-
being raised on millions of
no longer contain enough of
tain minerals are starving us
of
them we
enormously
eat.
in value,
eating as food. rectly
The
Our
truth
cer-
—no matter how much is
that our foods vary
and some of them aren’t worth
physical well-being
dependent upon the minerals
1
we
is
more
di-
take into our
Introduction
systems than upon calories or vitamins or upon the precise proportions of starch, protein or carbohydrates
we consume. Laboratory
fruits,
the vegetables, the grains, the eggs, and even
tests
prove that the
the milk and the meats of today are not
were
few generations ago.
a
enough
fruits
his
eat
stomach
he requires for perfect health,
salts
because his stomach
isn’t big
enough
to hold them!
are turning into a nation of big stomachs.
Do you know when mony
today can
and vegetables to supply
with the mineral
And we
No man
what they
those words were spoken in
before the Senate? Nineteen thirty-six!
lands are even
more
testi-
Today farm-
mineral-deficient and fertilizers
don’t fully replace those minerals.
Magnesium
is
still
one of the
most depleted minerals, yet one of the most important.
We
imagine that medicine has advanced to the stage of miracle cures, yet
it’s
nutrients that
not technology that we’re lacking but basic
power our bodies and
give us our health.
Quick-fix medical solutions from doctors are
all
around
us via television, the Internet, radio, and infomercials. In a
world of rapid change, our bodies are going through peaks and crashes every day.
We rely on
double cappuccinos
in the
morning, a Power Bar for lunch, and an acupuncture
treat-
ment
after
work
before
Harnessed to our
cell
we
go to the
gym
for our energy hits.
phone, laptop, Palm
Pilot,
and pager,
we’re exhausting our natural physical stores of energy, strain-
2
Introduction
ing our bodies’ capacity to function and heal. Although can’t
change our
environment,
digital
we
can learn
how
we to
preserve and rebuild our energy levels naturally.
Magnesium
more than 325 enzymes
regulates
in the
body, the most important of which produce, transport, store,
and
utilize energy.
lated
Many aspects
by magnesium, such
growth, and
as
cell
metabolism are regu-
DNA and RNA synthesis, cell
reproduction.
cell
of
Magnesium
also orchestrates
the electric current that sparks through the miles of nerves in
our body. Magnesium has numerous physiological
among which
roles,
are control of nerve action, the activity of
the heart, neuromuscular transmission, muscular contraction,
vascular tone, blood pressure, and peripheral blood flow.
Magnesium modulates and calcium from the
controls the entry and release of
which determines muscular
cell,
Without magnesium, muscle and nerve functions promised and energy
diminished.
is
We
activity.
are
com-
are operating with
the
power turned
ety,
heart attacks, arrhythmia, and even seizures and convul-
sions can result.
ral
to be an essential mineral.
life. 2
Yet
more ways it is
in the
in
Each year
United
States,
is
indis-
from the natu-
a gradual decline of dietary
from
a high of 500
the turn of the century to barely 175-225
3
since then,
which magnesium
continually being lost
food supply. There has been
magnesium
soft bones, anxi-
seventy-five years ago, scientists declared
research has revealed
pensable to
Muscular weakness,
1
More than magnesium
off.
mg/day
mg/day at
today. 3
The
Introduction
Academy
National
of Sciences has determined that most
Americans are magnesium-deficient, with men obtaining about 80 percent of the recommended daily allowance
(RDA) and women
averaging only 70 percent. 4
Too few
medical researchers and doctors are sounding the alarm, so
important that you inform yourself and protect your
it is
health. 5
’
6’ 7
THE CLINICAL IMPACT OF MAGNESIUM DEFICIENCY Magnesium was
first
discovered in huge deposits near a
Greek
city called Magnesia.
day
as
Epsom
and
still is
salts,
Magnesium
was used
to this day.
A
sulfate,
known
to-
in ancient times as a laxative,
1697 medical paper recommended
magnesium, with some exaggerated unscientific enthusiasm, for conditions as varied as skin ulcers, depression, vertigo, heartburn,
worms, kidney
Although we no longer cally
stones, jaundice,
and gout.
treat all of these conditions specifi-
with magnesium, current research does support
for a long
of ailments that
list
you
will read
about
its
in
use
The
Miracle of Magnesium.
The amount of research on staggering.
medical
To bring you
facts,
Eve
entific studies,
ment
that
sifted
the
the topic of
magnesium
is
most current research and
through thousands of pages of
sci-
each of which begins with the acknowledg-
magnesium
is
of therapeutic value in treating a
myriad of symptoms.
4
Introduction /
1.
Anxiety and panic attacks. Magnesium normally helps keep adrenal stress
2.
hormones under
control.
Asthma. Both histamine production and bronchial spasms increase with magnesium deficiency.
3.
Blood
clots.
Magnesium
has an important role to
play in preventing blood clots and keeping the blood thin 4.
—much
Bowel
like aspirin
disease.
but without the side
Magnesium
deficiency slows
the bowel, causing constipation,
down
which could
and malabsorption of nutrients
to toxicity
effects.
lead
as well as
colitis. 5.
Bladder spasms are worsened by magne-
Cystitis.
sium deficiency. 6.
Depression.
Serotonin,
which
dependent on magnesium. brain
is
more
also
A
mood,
elevates
is
magnesium-deficient
susceptible to allergens, foreign
substances that in rare instances can cause symp-
toms 7.
similar to mental illness.
Magnesium
Detoxification.
crucial for the re-
is
moval of toxic substances and heavy metals such
aluminum and 8.
from the body.
Magnesium enhances
Diabetes. facilitating
sugar
sium, insulin cells.
lead
is
as
metabolism.
insulin secretion,
Without
magne-
not able to transfer glucose into
Glucose and insulin build up
in the blood,
causing various types of tissue damage. 9.
Fatigue.
Magnesium-deficient
experience
fatigue
because
5
patients
dozens
commonly of
enzyme
Introduction
systems are underfunctioning. of 10.
magnesium deficiency
Heart
disease.
early
symptom
fatigue.
is
Magnesium
An
deficiency
is
common
people with heart disease. Magnesium
is
in
adminis-
tered in hospitals for acute myocardial infarction
and cardiac arrhythmia. Like any other muscle, the
Magnesium
heart requires magnesium.
is
also used
to treat angina, or chest pain. 11.
Hypertension. With insufficient magnesium, blood vessels
may go
into
spasm and cholesterol may
rise,
both of which lead to blood pressure problems. 12.
Hypoglycemia. Magnesium keeps insulin under control;
can 13.
without magnesium, episodes of low blood sugar result.
Insomnia. Sleep-regulating melatonin production
is
disturbed without sufficient magnesium. 14.
Kidney
disease.
Magnesium
deficiency contributes
to atherosclerotic kidney failure.
Magnesium
defi-
ciency creates abnormal lipid levels and worsening
blood sugar control 15.
in
kidney transplant patients.
Migraine. Serotonin balance
is
magnesium-dependent.
Deficiency of serotonin can result in migraine headaches and depression. 16.
Musculoskeletal conditions. gia,
Fibrositis,
fibromyal-
muscle spasms, eye twitches, cramps, and
chronic neck and back pain
may
be caused by mag-
nesium deficiency and can be relieved with magnesium supplements.
6
Introduction
17.
Nerve problems. Magnesium
alleviates peripheral
nerve disturbances throughout the body, such as migraines,
and
muscle contractions, gastrointestinal spasms,
calf, foot,
and toe cramps.
treating the central nervous
It is
also used in
symptoms
for vertigo
and confusion. 18.
Obstetrical
and
gynecological problems.
Magne-
sium helps prevent premenstrual syndrome and
dysmenorrhea is
(cramping
pain
important in the treatment of
viates
during infertility,
menses),
and
alle-
premature contractions, preeclampsia, and
eclampsia in pregnancy. Intravenous magnesium
is
given in obstetrical wards for pregnancy-induced
hypertension and to lessen the risk of cerebral palsy
and sudden infant death syndrome (SIDS). Magne-
sium should be
a required
supplement for pregnant
women. 19.
Osteoporosis.
Use
of calcium with vitamin
enhance calcium absorption without
a
D
to
balancing
amount of magnesium causes further magnesium deficiency,
which
triggers a cascade of events lead-
ing to bone loss. 20.
Raynaud's syndrome. Magnesium helps relax the spastic
blood vessels that cause pain and numbness of
the fingers. 21.
Tooth decay. Magnesium deficiency causes an unhealthy balance of phosphorus and calcium in saliva,
which damages
teeth.
7
Introduction
Drugs such tisone,
many
and cor-
as painkillers, diuretics, antibiotics,
of which are inappropriately used for the afore-
mentioned conditions, further deplete magnesium and other minerals, allowing trol.
symptoms
to get completely out of con-
Surgery, malnutrition, third-degree burns, serious in-
juries,
pancreatic inflammation, liver disease, malabsorption
disorders, diabetes,
hormonal imbalance, and cancer
are
all
seriously stressful medical conditions requiring increased
amounts of magnesium.
MY HISTORY WITH MAGNESIUM In
my second year of medical school,
obstetrics
ward when
a
was observing
I
young woman
in the
in the last stage of la-
bor developed rapidly elevating blood pressure and began convulsing. This was a true medical emergency. Already skeptical
drugs, I
about the antihypertensive and anticonvulsant
which had so many
side effects
and variable
wondered what could possibly work
dangerous for the baby. But
clearly, this
thing both powerful and effective.
would not be
that
woman needed some-
The attending physician
called out for an
ampule of magnesium
ately injected
into her IV. Within minutes the
it
results,
sulfate
and immedi-
woman’s
convulsing had ceased and her blood pressure was returning to normal.
I
was amazed, and IVe never forgotten
miracle of magnesium, which also reinforced
my
that
belief that
there are safe, effective alternatives to prescription drugs for
pain and chronic disease. In addition to
8
my
medical school
Introduction
training,
voraciously read
I
alternative medicine.
could find on nutrition and
all I
even studied acupuncture. Immedi-
I
ately after medical school
I
embarked upon
my naturopathic and ten years
training. In thirteen years of treating patients, as a researcher, writer,
found myself acting
and consultant,
I
have frequently
an educator, passing on the knowl-
as
edge of simple, safe treatments and supplements that really
work, including magnesium. But
my
keen interest
as professional.
magnesium
in
had taken
I
is
personal as well
calcium/magnesium supple-
a
many years, knowing the importance
ment
for
own
health.
however,
I
When
at night,
nation to 500
mg
mg
of
my
daily heart palpitations, calf
and neck and shoulder muscle ten-
magnesium
sion were related to
dosage from 200
my
started doing research for this book,
I
realized that
muscle cramps
of each to
a
day
in a
deficiency. Increasing
my
calcium/magnesium combi-
magnesium oxide twice
a
day stopped
the palpitations and the cramps and eased the muscle ten-
sion considerably.
Magnesium maceutical It is a
not some wonder drug touted by a phar-
company
in
an aggressive marketing campaign.
simple element, a mineral
easily obtained.
the
is
The more
more convinced
I
am
opportunity by not making
hope
that
by writing
I
vital to life
and health, and
have learned about magnesium,
that doctors are missing a it
huge
one of their “drugs of choice.”
this story of
you keep yourself healthy and
magnesium,
at the
I
will help
same time provide an
important resource that you can share with your doctor.
9
I
/
PART ONE The History of Magnesium
CHAPTER The Case
for
1
Magnesium:
The Personal History of an Element
Mary joked
though she was constantly being
that she felt as
run over by a slow-moving bus. Cramping in her tled her
awake
at night,
had heart palpitations had high blood sugar insulin, but
legs star-
making her an insomniac, and she
daily.
Her doctor
also
found
that she
—not bad enough to need injections of
he prescribed
pills to try to
stimulate
more
sulin production. Finally, frightening panic attacks
out of nowhere and afraid to
To cium sleep.
made
this vibrant,
at night, first,
having read that the calcium
bed, her calf muscles
would
where she would
lie
it
Mary began
was good
seemed to
or two, the pains got worse.
floor,
came
woman
go outside.
try to relieve her leg cramps,
At
fun-loving
in-
If
she
seize
for cramps and
help, but after a
yawned and
week
stretched in
up and catapult her
frantically
13
taking cal-
to the
massaging her muscles
The Miracle of Magnesium
to try to release the spasm. All the next day, she
about with
a
very tender, bruised feeling in her
would limp
calf.
Although Mary’s heart palpitations had improved some-
what
after she’d given
up her three cups of coffee
a day, they
too resumed after a few weeks. Every time the palpitations
made her
occurred, which was several times a day, they
cough
slightly
and catch her breath. She found
even though her doctor said her
ing,
disease
were
fine
it
frighten-
stress tests for heart
and she didn’t need further testing with an
angiogram.
Both Mary’s parents had had adult-onset
Mary knew
that she should
watch her
diet,
diabetes,
and
but she was
overweight and craved sugary and high-carbohydrate foods that
were hard to
resist.
of everything else,
came
to
my
office.
When
the panic attacks hit
Mary knew
she had to seek help, and
She was only
to be feeling so bad,
on top
fifty-three, far
too young
and was worried about her future
health.
Sam was only At
first,
he thought they were indigestion, but sometimes
would occur
the pains
cerned, he
blocked
forty-nine and experiencing chest pains.
went
in the
middle of the night. Con-
to a cardiologist,
arteries,
who found two
slightly
not serious enough for bypass surgery.
Sam’s cholesterol was somewhat elevated, as was his blood pressure,
and the
which he attributed fact that
past six months,
to his high-stress occupation
he had not exercised regularly for the
when he was
14
sidelined with back pain.
The Case for Magnesium
The
cardiologist observed that his arterial blockage
would
almost inevitably worsen over time and eventually necessi-
The doctor
tate surgery.
cholesterol, told
him not
nitroglycerine to take
him medication
offered
Sam
tions.
and gave him
to eat butter or eggs,
whenever he had the
symptoms got worse, he would
pain. If the
prescribe other medica-
couldn’t imagine having to wait to get worse be-
knew
fore doing something about his chest pain; he
must be something more he could do
came
to
At
me
thirty-five,
also
to avoid surgery
and
Jan had actually begun to look forward
how bad
menopause. That’s
symptoms were. As soon she was hit
there
for advice.
to going through '%
for his high
as
PMS
her
those horrible feelings
lifted,
by the sledgehammer of menstrual cramps. She
had migraines, which for years had come before her pe-
riod but
now were
occurring once or twice a week. She was
so miserable that she
was considering
a
complete hysterec-
tomy, with removal of her hormone-producing ovaries, but
wondered whether the migraines, ing
all
were happen-
month, were not actually hormonal.
Different as their suffer
since they
symptoms
from magnesium
deficiency.
seem equally susceptible
may become
culating red blood less
to
pound cells,
magnesium
Mary, Sam, and Jan
While
magnesium
deficient faster than
fluctuations because
perhaps
are,
for
women
and
deficiency,
men due
to
all
men
women
hormonal
pound, they have fewer
cir-
which carry magnesium, and so available.
15
There are
a
few other
The Miracle of Magnesium
gender differences. Because of magnesium’s effect on hor-
monal regulation and
when
pregnancy,
cies in
vice versa,
women
can have deficien-
breast-feeding, with premenstrual
syndrome (PMS), and with dysmenorrhea Osteoporosis, which affects more
dence of
a deficiency of
overactive thyroid,
made
ATP
than men,
evi-
is
both calcium and magnesium.
which
An
more women than men,
afflicts
which uses up magnesium-
increases the metabolic rate,
requiring
women
(painful periods).
(adenosine triphosphate
in each cell in the body).
—the energy packets
Without magnesium,
ATP
would not be produced. Let’s follow
came
their
Mary, Sam, and Jan and see
magnesium
When Mary detail,
me,
I
charted her health history in
according to procedures
commonly used by
pathic doctors, and found several
much
needed I
it
symptoms
a
of
naturo-
magnesium
had been made even worse by too
magnesium supplemen-
calcium, however, so simple
tation wouldn’t be
they over-
deficiencies.
visited
deficiency. In her case
how
enough
for Mary.
Her
diet
and
lifestyle
complete overhaul.
gave
needed to
Mary
start eating,
and seeds such that she’d
a list of
as
magnesium-rich foods that she
which included
nuts, beans, greens,
sunflower and pumpkin.
been avoiding almost
all
at the
gas,
and greens
supermarket. She had
never even thought about eating seeds.
16
realized
of these foods: She
thought nuts were fattening, beans gave her never seemed fresh enough
Mary
The Case for Magnesium
After a
week
of enthusiastically eating a lot
magnesium-rich foods, Mary
felt
somewhat
better.
more
To make
sure she could get fresh organic greens regularly, she tracked
down
a local
community-supported agriculture (CSA) pro-
gram and bought
a share in a
neighboring organic farm.
Mary
how
and cook beans to prevent
also learned
them from causing in
gas,
to soak
and began eating nuts and seeds rich
magnesium and healthy
oils,
pecans, sunflower seeds, and
After her second taking
a day,
we added
months
to eliminate
that not
all
her
I
seeds.
recommended
mg
Her
every two days to
cautioned her that
it
could take
magnesium deficiency symptoms and
symptoms would
necessarily respond.
two months, however, Mary was singing nesium.
that she begin
Starting with a dosage of
another 200
build slowly to 600 mg.
almonds, walnuts,
as
pumpkin
magnesium supplements.
mg
200
visit I
such
Her palpitations and panic
the praises of
attacks
cravings for sweets were fewer, she
Within
mag-
had disappeared.
was
able to control
her blood sugar with diet alone, and tests for blood sugar
were normal. Her
leg
cramps were gone, and with them her
insomnia. At three months
magnesium so
that she
we added
calcium along with
would not develop an imbalance of
the two. Mary’s internist
was quite surprised
at
her im-
proved health and told her to keep up the good work with her diet and supplements.
Sam had an start
inquiring mind, and
reading about heart disease.
17
I
He
encouraged him to
found that up to
The Miracle of Magnesium
30 percent of angina (chest pain) patients do not have badly
blocked
arteries
balance that
may
but
be suffering from an
electrical
driven by mineral deficiency, most
is
monly magnesium.
1
An
im-
com-
astonishing 40 to 60 percent of
sudden deaths from heart attack may occur
in the
complete
absence of any prior artery blockage, clot formation or heart
rhythm abnormalities, most (magnesium
arteries
from spasms
a natural antispasmodic). 2
’
3 ’4 5 ’
in the
More-
found that magnesium deficiency has been linked
over, he
to
is
likely
sudden cardiac death. Sam didn’t want to wait around
for that to
happen to him; he was determined
what was causing
his
problem and
treat the cause.
he read, the more intrigued he became.
magnesium deficiency
back pain, that
especially
When
also associated
is
to find out
The more
he read that
with muscle pain,
really got his attention, since
had begun having back pain four or
five
he
months before he
began to develop chest pain. 6
With back to ever, a
a
packet of information on magnesium,
Before the doctor saw him, how-
his cardiologist.
nurse took Sam’s blood pressure;
elevated, even
though
Sam went
at
home
it
it
was unusually
was usually only
points above normal. (Doctor-induced hypertension
monly reported by the
The
patients.)
room and immediately began
sure medication.
is
a
com-
cardiologist swept into
talking about blood pres-
Sam countered with magnesium. The
diologist visibly cooled
and
said that
effects,
18
car-
magnesium was used
to control hypertension that occurred in pregnant
because there were no side
few
women
but that there were
The Case for Magnesium
plenty of effective drugs for everyone
he would rather not have side effects gathered up his
file
When Sam
else.
said
either, the cardiologist
and told him to come back when he was
ready to take medications for his heart disease.
When Sam came back to see me, he was still pretty upset by
this
encounter; he didn’t like the specialist refusing to
discuss a possible ture.
ment
Sam and for
him
magnesium deficiency
as part of the pic-
agreed that magnesium seemed the best treat-
I
to initiate at this time since he
was not
willing
by
eating
to take medications.
Sam began adding magnesium magnesium-rich foods. After but he
still
to his diet
week he
a
felt
much
calmer,
had chest and back pain. So he added magnesium
and calcium supplements, and
about three months he
in
felt
almost normal.
Among
the studies
Sam
read was one that looked at the
correspondence between type
A
personalities
and magne-
sium deficiency. From the description, Sam realized he was a
type A, an aggressive guy
who
lived
on
adrenaline, time
pressure, and stress. This type of behavior drains the
of
magnesium and can
body
lead to disorders such as heart disease,
muscle spasms, hypersensitivity, and
irritability. 7
Prolonged
psychological stress raises adrenaline, the stress hormone,
which depletes magnesium. 8 Both Sam’s back and chest pain
would ways he
hit
when he was under
to control his stress and
knew he
couldn’t avoid
Sam added an
extra 200
mg
stress.
So Sam worked on
added more magnesium when
it.
of
19
On
days
when
magnesium
he exercised,
to his diet, since
The Miracle of Magnesium
sweat loss during heavy exercise (cycling and jogging) and
working
won’t replace the
magnesium. Just drinking water
in the heat deplete
many
lowered
all
the minerals lost.
factors that affected his
his cholesterol
chance of
a heart attack
and
By paying mind-body
stress levels
attention to health,
Sam
and reduced
his
and of needing surgery to unblock
his arteries.
Jan heard that yoga might help her riods,
and she
really
needed
The teacher
a vegetarian.
the detox class
One
doesn’t
empty once
into the
body from more
if
the colon. is
PMS
The longer
During cooking
the
bowel
reabsorbed back debris
sits in
the
and endometriosis, which causes
classes,
by some natural-health ex-
body but
toxicity
9
.
Jan faced the fact that she was a
junk food addict. Magnesium in the
If
reabsorbed, making stools solid and
worsen with constipation and
enzymes
things Jan learned in
she had one a week.
painful periods, are considered perts to
up everything” and
a day, toxins can be
fluid
to pass.
difficult
first
when
to join
was the importance of having regular bowel
movements. Jan was lucky
colon, the
of the
took
also ran regular
which Jan decided
classes,
she realized she didn’t have to “give
become
and painful pe-
to learn to relax, so she
classes at a local health club.
detox and cooking
PMS
is
is
necessary in hundreds of
almost totally lost during the
processing of packaged and fast foods.
The older women
in
her class were suffering from a variety of problems that in-
cluded cancer, heart disease, and osteoporosis.
20
Is that
how
The Case for Magnesium
she
would end up
care of her health
in ten or
twenty years
if
now? Learning how many
she lacked in her diet
Her new
made her marvel
she didn’t take basic nutrients
that she wasn’t even
more
ill.
seeds,
which cleared up her constipation and almost
nated her
me on
PMS
diet included greens, beans, nuts,
and painful periods.
When
the advice of her yoga teacher,
the right track.
I
recommended
it
was
min; with
all
elimi-
she came to see
was on
clear she
that she begin taking a
nesium supplement along with calcium and her lifestyle changes, she
and
mag-
a multiple vita-
felt like a
MAGNESIUM, THE SPARK OF
new
person.
LIFE
In a poetic reference to magnesium’s crucial role in evolu-
Aikawa
tion, Dr. Jerry
magnesium to
man and
of the University of Colorado calls
the ur-mineral, the living
all
organisms
.
most important mineral
10 It is
critical to the
meta-
bolic processes of lowly one-celled living organisms and is
the second
Magnesium with
all
most abundant element
existed at the beginning of
inside life
human
cells.
and was involved
aspects of cell production and growth.
When plants
evolved to use the sun as their energy source, magnesium
played in
a pivotal role in the
development of chlorophyll. So
both plants and animals, magnesium became an
essential
enzyme processes
affecting
mineral involved in hundreds of
every aspect of
life.
Presently, seventeen minerals are considered essential
21
The Miracle of Magnesium
for
human
will be
study
life,
and
it is
more minerals
quite possible that
found to be indispensable
as
we
take
more time
mineral connection. Ninety-nine percent of the
life’s
body’s mineral content
made up
is
of seven macrominerals:
sodium, potassium, calcium, phosphorus, chlorine,
and magnesium. The other minerals.
As with most
naturally with sulfur to
minerals, the element
magnesium
make Epsom
salts
joins
It
(magnesium
sul-
with carbon to make magnesium carbonate, and with
calcium to
make dolomite. Magnesium
partnership with is
sulfur,
percent comprises ten trace
1
occurs in nature combined with other elements.
fate),
to
silica in talc
acid,
nesium compounds are antacids used to first
chemistry.
in it
and some mag-
treat heartburn.
encounter with magnesium was in high school
Each student was given
and told to
found
and asbestos. Like calcium,
an alkaline mineral, which neutralizes
My
also
is
light
one end
a thin strip of
carefully.
had learned that magnesium
is
magnesium
The previous week we
the eighth
most abundant
ele-
ment, constituting approximately 2 percent of the earth’s crust
and 1.14 percent of seawater. By comparison, calcium
makes up
3 percent of the earth’s crust but only 0.05 percent
of seawater. There are 4-6 tsp (20-28 g or 2 oz) of
sium
in the body,
comprising about 0.05 percent of the
body’s weight. This information in no the
dynamic
up
like
magne-
effect of lighting the
way prepared
magnesium
us for
strip. It flared
an electric sparkler and disappeared in a
flash.
This
effervescent property serves as an important reminder of
22
The Case
magnesium’s
Magnesium
for
versatility as the spark of
constantly ignit-
life,
ing metabolic reactions throughout the body.
THE BODY The impulses from
for any and
movement
body
arise
These microcurrents of
elec-
all
electrical transmission.
tricity that pass
ELECTRIC
IS
along the nerves were
in the
measured
first
in
1966. Scientists soon discovered that the conductor for
was calcium and
these bodily electrical currents
sium was necessary to maintain the proper
More
in the blood. 11
enters the cells
that
magne-
level of
calcium
recent research indicates that calcium
by way of calcium channels
that are jeal-
ously guarded by magnesium. Magnesium allows a certain
amount
of calcium to enter a cell to create the necessary
and then immediately helps to
electrical transmission,
Why?
the calcium once the
work
mulates in the
causes toxicity and disrupts
tion.
cell, it
Too much calcium
is
done.
If
eject
calcium accu-
entering cells can cause
cell
func-
symptoms
of heart disease (such as angina, high blood pressure, and ar-
rhythmia), asthma, or headaches.
cium channel blocker. 12
’
teeth.
of
all
our magnesium
fluids.
and brain
so
is
housed
muscle and tissue
The highest concentrations
cells,
nature’s cal-
The remaining 35-40 percent
in the rest of the body, including
body
is
13 ’ 14
About 60-65 percent our bones and
Magnesium
it is
no wonder
23
that the
is
in
found
cells
and
are in the heart
major symptoms
The Miracle of Magnesium
of
magnesium deficiency
two organs
are also the activity
measured by
that have considerable electrical
EKG
(electrocardiogram) and
Our blood
(electroencephalogram).
and brain. These
affect the heart
contains only
1
EEG
percent
of the body’s total magnesium.
Magnesium mostly works ducing
ATP
energy packets for our body’s
triggering production of
revving up messenger
DNA,
production of
building blocks of
magnesium
inside our tissue cells, pro-
all
RNA.
It is
our genetic code. Both of the basic
life,
RNA
and
DNA,
are
dependent on its sta-
DNA and the structure of chromosomes,
on
magnesium
an essential cofactor in almost
tems involved in the processing of
DNA.
without sufficient magnesium,
comes
by
also a requirement for the
to maintain stable genes. 15 In addition to
is
and
the body’s protein structures
bilizing effect
that
vital force
all
enzyme
sys-
Research shows
DNA
synthesis be-
sluggish.
WHAT DOES MAGNESIUM DO? Magnesium’s hundreds of be divided into
1.
activities in the
human body
can
five essential categories: 16
Magnesium
is
a cofactor assisting
enzymes
in cata-
lyzing most chemical reactions in the body, including
temperature regulation. 2.
Magnesium produces and
3.
Magnesium
is
transports energy.
necessary for the synthesis of protein.
24
The Case for Magnesium
4.
Magnesium
5.
Magnesium
1.
helps to transmit nerve signals, helps to relax muscles.
COFACTOR Enzymes 2.
IN
CHEMICAL REACTIONS
are protein molecules that stimulate every chemi-
cal reaction in the
body. Magnesium
is
make
required to
hundreds of these enzymes work.
PRODUCING AND TRANSPORTING ENERGY Magnesium and
the
B-complex vitamins
are excellent
ples of energy nutrients, because they activate
exam-
enzymes
that
control digestion, absorption, and the utilization of pro-
and carbohydrates. Because magnesium
teins, fats,
is
in-
volved with hundreds of enzymatic reactions throughout the body, deficiency can affect every aspect of
life
and cause
3.
symptoms. Of the 325 magnesium-dependent
a score of
enzymes, the most important enzyme reaction involves the creation of energy
by
activating adenosine triphosphate
(ATP), the fundamental energy storage molecule of the body.
ATP may
be what the Chinese refer to
Magnesium energy.
is
required for the
body
Without magnesium there
ment, no
life. It is
is
to
as qi
or
life
force.
produce and store
no energy, no move-
that simple.
SYNTHESIZING PROTEIN Magnesium
is
used in synergy with dozens of other
vita-
mins and minerals to create structural components of the body. Under the direction of magnesium, enzymes and
25
The Miracle of Magnesium
nutrients
modify the building blocks from food to
the body.
Without magnesium, there
is
RNA
no body.
DNA,
which contain the genetic blueprints
tion of
all
create
and
for the forma-
the protein molecules in the body, are also depen-
dent on magnesium.
4.
TRANSMITTING NERVE SIGNALS
Magnesium permits calcium electrical
brain.
to enter a nerve cell to allow
transmission along the nerves to and from the
Even our thoughts,
via brain neurons, are
dependent
on magnesium.
RELAXING MUSCLES
5.
Calcium causes contraction
magnesium causes cium and
in skeletal
relaxation.
insufficient
When
muscle
there
is
too
fibers,
and
much
cal-
magnesium, you can get sustained
muscle contraction: twitches, spasms, and even convulsions.
Smooth muscles cient
directed
magnesium can
by too much calcium and
insuffi-
tighten the bronchial tract, causing
asthma; cause cramping in the uterus and painful periods;
and cause spasms
in
blood
vessels, resulting in hypertension.
THE DANCE OF CALCIUM AND MAGNESIUM Calcium and magnesium share equal importance bodies.
Newtons law
says that for every action there
equal and opposite reaction, and calcium and
dance within
this law.
in
Neither can act without
26
our is
an
magnesium
eliciting a re-
The Case for Magnesium
from the
action
At the biochemical
other.
and calcium are known to
act antagonistically
Many enzymes whose
other.
a sufficient
amount
rimentally affected calcium.
Growth
of
magnesium
will be det-
and intermediary
metabolism are also absolutely dependent on the
which can be compromised
of magnesium, is
if
availability
excess calcium
present. 17
To understand how you can imbalance in your kitchen. 1
depend on
increases in levels of cellular
cell division,
cells,
towards each
activities critically
of intracellular
by small
magnesium
level,
Crush
own
create a
calcium/magnesium
body, try this experiment in your
a calcium pill
oz of water. Then crush
a
and see
magnesium
When you
into the calcium water.
how much pill
The same
heart, brain, kidneys,
and slowly
stir it
introduce the magne-
sium, the remaining calcium dissolves; water-soluble.
dissolves in
becomes more
it
thing happens in your bloodstream,
and
all
the tissues in your body. If
you
don’t have enough magnesium to help keep calcium dissolved,
you may end up with calcium-excess muscle spasms,
fibromyalgia, hardening of the arteries, and even dental cavities.
there
is
Another scenario plays out too
magnesium
much
in
the kidneys. If
calcium in the kidneys and not enough
to dissolve
it,
you can
get kidney stones.
All muscles, including the heart and blood vessels, contain
more magnesium than
cient,
calcium.
If
magnesium
calcium floods the smooth muscle
vessels vessels
cells
is
defi-
of the blood
and causes spasms leading to constricted blood and therefore higher blood pressure,
27
arterial
spasm,
The Miracle of Magnesium
angina, and heart attack. 18
sium
A
proper balance of magne-
symptoms.
in relation to calcium can prevent these
Calcium
excess, stimulating the cells in the
muscular layer of
the temporal arteries over the temples, can cause migraine
headaches. Excess calcium can constrict the smooth muscle
surrounding the small airways of the lung, causing stricted breathing
and asthma.
without the protective
effect of
Finally, too
much
magnesium, can
calcium,
irritate deli-
cate nerve cells of the brain. Cells that are irritated
cium
fire
electrical
re-
by
cal-
impulses repeatedly, depleting their
energy stores and causing
cell
death.
THE CALCIUM DISTRACTION The irony of
the calcium-magnesium story
magnesium calcium
will
is
that without
not work properly. Both our cur-
rent diet and tendency to oversupplement with calcium,
however, make getting enough magnesium almost impossible.
Research shows that the ratio of calcium to magnesium
in the paleolithic or
caveman
evolved with our bodies
—was
— the ancient
1:1,
ratio in present-day diets. 19
15:1
times there in
diet
compared with
had
a 5:1 to
With an average of ten
more calcium than magnesium is
diet that
in
our current
diet,
no doubt about widespread magnesium deficiency
modern
times.
The emphasis on calcium supplementation has
diverted
our attention from any other mineral, even though
all
minerals are crucial to the proper functioning of the body.
28
The Case for Magnesium
In our society
we
important,” “the
teamwork
tend to look for “the best,” “the most
star,”
and forget that
takes a team and
to get anything accomplished, including
processes. Calcium, because eral in the
it
it is
the
most abundant min-
body, therefore became “the
research has accumulated
four decades,
it
body
star.”
Even though
on magnesium over the past
has never been adequately publicized and
discussed.
29
V.
CHAPTER
2
Magnesium: The Missing Mineral
A
1988 U.S. government study concluded that the standard
American
diet failed to provide the daily
magnesium.
That was
1
decade and
a
requirement of
a half ago,
can be sure that most people get even
junk food makes up 27 percent of our
and you
less today,
when
Mildred
Seelig,
diet.
M.D., and many other magnesium experts have also come to the inescapable conclusion that the typical diet,
which
is
rich in
phosphates, protein, ally increases the
National
fat,
fiber,
sugar, salt, synthetic vitamin
D,
and supplemented calcium, actu-
need for dietary magnesium. In 1997, the
Academy
of Sciences found that most Americans
are magnesium-deficient.
of the
American
When men
minimum requirement
merable body functions and
of
magnesium
women
30
obtain only 80 percent
at
to run innu-
70 percent get even
Magnesium: The Missing Mineral
less
of
what they absolutely need, then our bodies
are just
not able to function properly 2 .
Let’s
look
at
some
of the reasons
you may be lacking
in
magnesium.
PROCESSED FOOD LACKS MAGNESIUM During the refining and processing of food,
significant
The process
of extract-
amounts of magnesium can be ing oils
from magnesium-rich nuts and seeds
this essential mineral.
lost
lost.
Nearly
all
the
magnesium
during the milling process to make
flour.
strips
away
in grains
is
Chemicals
that are used in the preparation of frozen vegetables to pre-
serve their rich green color result in a lowered
content. Finally, in the kitchen,
magnesium
when
magnesium
vegetables are boiled,
leaches out into the water.
PERCENTAGE OF MAGNESIUM LOST DURING FOOD PROCESSING Refining of flour from
80 percent
wheat
Polishing of rice
83 percent
Production of starch from corn
97 percent
Extraction of white sugar from
31
molasses
99 percent
The Miracle of Magnesium
What can we do best to
buy organic foods,
but
for only a
still
eat as
magnesium sources?
many raw
It is
vegetables as
and when you do cook vegetables, quickly steam
possible,
them
to defend our
crisp.
few minutes
You can
until they are slightly
cooked
also save the nutrient-filled water to
use as soup stock.
STOMACH ACID IS ESSENTIAL FOR MAGNESIUM ABSORPTION stomach digestion and
Inefficient
lead to deficiencies of
magnesium.
intestinal absorption can
When you
rious physical or even emotional stress,
are
under
se-
your body might
not produce sufficient stomach acid, which
is
required for
digestion and for chemically changing minerals into an ab-
sorbable form.
The
elderly as well as people with arthritis,
asthma, depression, diabetes, gallbladder disease, osteoporosis,
or
gum
disease are often deficient in hydrochloric acid
All these conditions are also associated with
3 .
magnesium
deficiency.
On
the other hand, America’s
counter drug type
is
antacids.
number one
over-the-
Heartburn and indigestion,
the result of bad eating habits, plague the nation. But the
“cure” in this case
is
no
better than the disease.
The
roiling
and burning in the gut from sugary junk food and greasy fast
food
stomach
is
being inappropriately blamed on too
acid. In
tion in the
many
cases,
stomach and
a
heartburn
is
much
due to fermenta-
backflow of pancreatic enzymes
32
Magnesium: The Missing Mineral
from the small acids, antacids
intestine. 4
make
it
By
impossible for us to absorb minerals
or digest our food properly. further depleted
we
if
neutralizing normal stomach
Our magnesium
can be even
use calcium carbonate antacids be-
cause the calcium they contain causes
more magnesium
to
be excreted.
ABSORPTION OF DIETARY MAGNESIUM HINDERED Magnesium
is
ultimately absorbed into the bloodstream from
the small intestine. In general, an average of only 50 percent
of ingested
magnesium
the stool or urine.
is
absorbed; the rest
is
eliminated in
A number of conditions influence the de-
gree of absorption:
•
Whether the
• Availability
intestines are healthy or diseased
of the protein transport molecule for
magnesium •
Availability of parathyroid
•
The
rate of
hormone
water absorption, because magnesium
is
soluble in water •
The amounts
of calcium, phosphorus, potassium,
sodium, and lactose (milk sugar) in the body,
which •
inhibit
all
of
magnesium absorption
Supplemental iron, which can impede magnesium absorption and vice versa take
them
(if
you
several hours apart)
33
take both,
you should
The Miracle of Magnesium
MAGNESIUM BLOCKED BY CERTAIN FOODS A
may be high or low in magnesium, but you should know that certain foods contain magnesium antago-
food
also
such
nists,
as oxalic acid,
which
is
found
in spinach
and
chard, or phytic acid, found in the hulls and bran of seeds
and
grains. Oxalic acid
and phytic acid can form insoluble
compounds with magnesium, causing
to be eliminated
it
rather than absorbed. Saturated fats (from meat and cheese)
can bind with mineral compounds in food, making insolu-
end up forming plaque
ble
clumps of
ies
and blood vessels (atherosclerosis) and can eventually
raise
fat that
your blood pressure and lead
magnesium supplements with
in
your
arter-
to heart disease. Taking
a fatty
meal
is
a waste.
Mag-
nesium supplements are best taken on an empty stomach. There
is
much
evidence that a high-protein diet only
makes magnesium deficiency worse, and ing such a regimen,
you should
if
you
take at least 300
are follow-
mg
of sup-
plemental magnesium. 5
Soybeans, too, are high in phytic acid, which intercepts minerals from
all
foods and blocks their uptake and absorp-
tion in the intestinal tract. People
legumes
as their
deficiencies.
who depend on grains and
main source of protein often have mineral
Soy has one of the highest phytate
legume and, unlike others,
its
phytic acid
is
levels of
not destroyed
with extended cooking time. Only fermentation in the
any
(as is
done
production of miso and tempeh) will reduce the
phytic acid levels of soy.
34
Magnesium: The Missing Mineral
who
Vegetarians,
and
dairy, risk
substitute unfermented tofu for meat
having severe mineral deficiencies. Moreover,
the menopausal population
may
be overusing soy (for
its
natural phytoestrogenic effects) and developing similar mineral deficiencies.
As
a
cheap alternative to meat, soy
(as
soy
protein isolate and textured vegetable protein) has exploded
on the school lunch scene and
much soy really
Too
in the fast-food industry.
can cause mineral deficiencies in children,
who
need their minerals to build strong bones and teeth
the structure for adult health.
A JUNK-FOOD DIET IS NOT A MAGNESIUM DIET Even
in a healthy diet
addition of 150
mg
with proper protein intake, the
magnesium
of elemental
a
day can make
dramatic changes in health. 6 (See Chapter 13 for a
full dis-
cussion of magnesium supplementations.)
diet
leave
you magnesium-deficient,
undermine your
We
a
poor
If a
good
can
diet can seriously
health.
live in strange times,
when people
avidly watch
gourmet-cooking shows while devouring junk food. Junk food provides 27 percent of most peoples daily astounding 90 percent of our food dollar processed foods. People
such
who
as hospitals, colleges,
people
is
an
spent on
eat primarily in institutions,
or hotels, tend to consume only
cooked and processed foods and deficient, as are
calories;
who
are likely to be
magnesium-
drink only soft water because
35
The Miracle of Magnesium
water-softening agents eliminate magnesium
water
magnesium, and
deficient in
is
7
Fluoridated
.
water pulls
distilled
minerals out of the tissues and flushes them out of the
who
body. People
drink soda and soft drinks
may
also be
magnesium-deficient because sugar uses up magnesium
Carbonated
and processed
beverages
.
8’9
(luncheon
foods
meats and hot dogs) contain phosphates, which bind with
magnesium is
to
make
insoluble
magnesium phosphate, which
not absorbed by the body. People
who consume more
than three alcoholic drinks a day can also be deficient because alcohol blocks absorption and enhances excretion of
magnesium
10 .
Coffee also acts
as a diuretic,
magnesium out of the body. Dieting cially
by using
and
very unhealthy.
is
diuretics,
which hastens
to lose weight, espe-
can drain the body of magnesium
MAGNESIUM-DEFICIENT SOIL RESULTS IN DEFICIENCY Even
if
you
come up sium.
whole
try to eat
magnesium-rich foods, you can
short because the soil
Magnesium
is
found
grains, but this
is
magne-
itself is deficient in
in vegetables, nuts, seeds,
true only under optimal
still
and
growing
conditions. Plants
grown on depleted
soil
on factory farms
contain very
magnesium because
it is
not routinely in-
cluded in
little
fertilizer. If
there
is
no magnesium
in the soil,
plants will have none; they cannot manufacture
thin
air.
So don’t believe
it
when someone
36
it
says that
out of
you can
Magnesium: The Missing Mineral
get
all
your nutrients
true only
if
you
farmers use a
full
good, balanced
spectrum of nutrients
To
the organic
if
in their fertilizer, in-
enough magnesium
get
you probably need
That may be
diet.
food and only
eat organic
cluding magnesium. today,
in a
in
your
diet
to take supplements.
DRUGS CAUSE MAGNESIUM DEFICIENCY Ironically, Seelig,
one of the foremost magnesium experts, Mildred
M.D., began her research career over forty years ago
working for drug companies. that
many
It
was there she
noticed
of the side effects of drugs were actually magne-
sium deficiency symptoms. cause increased for example,
demand
by
It
seemed
to her that
tralize the acid
which then
creating acidity in the body,
and minimize
to deplete
its
cells to try to
the
body
neu-
Other drugs
toxic effects.
magnesium from
many drugs
magnesium
for and utilization of
draws on available magnesium from the
seemed
first
or,
conversely,
manifest their positive effects because they increase the level of
magnesium
in the
body
11 .
The following drugs can
create
magnesium
deficiencies
•
Common diuretics
•
Birth control
•
Insulin
•
Digitalis, prescribed for
•
Tetracycline and certain other antibiotics
•
Cortisone
pills
some
37
heart conditions
12 :
The Miracle of Magnesium
DRUG INTERACTIONS WITH MAGNESIUM Other drugs
magnesium
interact with
For example, magnesium
is
a
in specific
muscle relaxant, so
it
ways. 13
enhances
the actions of prescription muscle relaxants such as tubo-
curarine (used in surgery), barbiturates, hypnotics, and narcotics.
These medications may be decreased under
doctor’s supervision
if
you
are
anesthesiologist before surgery
if
on magnesium.
you
are taking
Tell
a
your
magnesium
supplements.
Magnesium cial
during
protects the kidneys, so
with
treatment
(which result
in
it
may
aminoglycoside
be benefiantibiotics
magnesium wasting) and immunosuppres-
sant drugs such as cyclosporin and cisplatin. Discuss this
with your doctor. Diuretics and cardiac drugs waste magnesium. Additional
magnesium intake
tration of diuretics
is
recommended during adminis-
and cardiac glycosides. Check with your
doctor.
Magnesium
inhibits the absorption of iron, tetracyclines,
ciprofloxacin, vancomycin, isoniazid, chlorpromazine,
methoprim, nitrofurantoin, and sodium these medications
two
to three hours before or after
nesium supplements. (Sodium fluoride osteoporosis
fluoride.
is
8.)
38
Take
mag-
prescribed for
—although taking magnesium may be
choice; see Chapter
tri-
a wiser
Magnesium: The Missing Mineral /
WHY HAVEN’T WE HEARD ABOUT MAGNESIUM? The
vast majority of us
were not exposed to nutritional
education in school. But what about doctors? As you suspect, doctors generally
may
do not learn about nutrition or
nutrient supplementation in medical school because they are studying disease, not wellness.
doctor,
you may think you
When you visit
are going there to
health or prevent illness, but doctors have
about
cate their patients
how
a
medical
improve your
little
time to edu-
to keep themselves well.
And
patients often will not change their lifestyle unless their
doctor
tells
them
to, believing that if
portant, the doctor
would have
told
vitamins were so im-
them
to take supple-
ments. (Of course, some patients don’t change the live
even
when
weight and eat
their doctor does
tell
first
second two years
for those diseases.
is
a
We
Have you heard
much
I
I
learned
all
about
studied drug treatments
spent no time on nutrient deficienthe expression
hammer, everything begins
very
to lose
HAMMER
IS A
two years of medical school
diseases; the
cies.
them they have
they
right.)
WHEN ALL YOU HAVE In the
way
“When
all
you have
to look like a nail”?
That
is
the case with doctors and drug treatments. But
even worse, with thousands of drugs in the pharmaceutical
39
The Miracle of Magnesium
compendium, on the
it is
quite impossible for doctors to keep
latest drugs,
and impossible to prevent
serious drug interactions. is
said to be scientific,
drug
And
most
up
side effects or
although allopathic medicine
patients are
on more than one
and there are no studies proving the safety of
at a time,
drug combinations.
According to magnesium expert Mildred
Seelig,
M.D.,
while a tremendous amount of magnesium research has been
done
in India, Britain, France,
and other European countries,
doctors in the United States use the excuse that not enough
them
to feel informed
calls this
the “not-invented-
research has been done here for
enough
to prescribe
it.
Dr. Seelig
here syndrome.” Pioneers such as Drs. Bella and Burton Altura,
however, continue to do original magnesium research
in this country.
Every year for the past forty years they have
produced on average
on magnesium and
a
dozen peer-reviewed journal
ionic
magnesium
convinces even die-hard skeptics to
become informed
— of the
testing.
articles
Their research
—when they take the time
clear
need for magnesium sup-
plementation and the absolute requirement for accurate testing.
DRUG COMPANIES FUND DRUG RESEARCH NOT MINERAL RESEARCH Medical science studies one symptom
and generally
tries to find
at a time, in isolation,
one cause for that symptom and
40
Magnesium: The Missing Mineral
one drug that it
treats
The
it.
makes
search for a drug that will eventually pay for the costly
studies necessary to bring
magnesium and is
bias of medical research
all life
Everyone agrees
to market.
that
indispensable for health, disease prevention,
is
processes, but
no money
it
in selling a
it
has been ignored because there
common
Magnesium can-
nutrient.
not be patented, so pharmaceutical companies do not engage in magnesium research. There
is
no advertising budget
magnesium, compared to the hundreds of millions of
for
on advertising prescription drugs;
dollars spent
nutrients
do
not get media attention. To make matters worse, over the past
two decades
from the pharmaceutical drug research
14
Scientific
.
industry,
which primarily funds
medicine ignores nutrient investi-
gation in favor of drugs. Older research health providers. Doctors
may have
magnesium offered some promise haven’t read any
come
the bulk of university funding has
new
also ignored
by
heard years ago that
in heart disease, but
studies, so they
ment must have not panned
is
assume that the
they
treat-
out.
Doctors seem to be waiting for
a large clinical trial, for
example, following twenty thousand people taking magne-
sium for been
life. It
would have been
initiated thirty years ago.
one now, but
And do we No. Do we
I
don’t
nice I
if
such a study had
would suggest
know who would pay
starting
for such a
trial.
have the luxury of waiting for those results? presently
know enough about magnesium
recommend widespread supplementation?
41
Yes.
to
The Miracle of Magnesium
An
major
analysis of seven
clinical studies
shows
that
intravenous magnesium reduced the risk of death by 55 percent after acute heart attack. These results were published in the prestigious British Medical Journal and the widely read
Drugs
.
As
15 ’ 16
I’ve noted, Drs. Bella
been researching magnesium and
and Burton Altura have
its clinical
application for
over forty years. 17 The ionized magnesium electrode, pro-
duced by Nova Biomedical (Waltham,
MA)
urging and tested
New York has given
University of
at State
at the Alturas’
doctors a reliable magnesium test and taken the guesswork
out of diagnosing magnesium deficiency. 18 Dr. Alexander
Mauskaup, working with the Alturas, has proven the connection between migraines and magnesium
many
over and puts magnesium treatment into practice
New
York Headache Center. 19 20 21 Dr. Mildred ’
’
times at the
Seelig has
contributed comprehensive reviews of magnesium at
New
York Medical College, the American College of Nutrition, and more recently sity of
at the
Department of Nutrition, Univer-
North Carolina. 22 23 Dr. Jean Durlach, president of ’
the International Society for the
on Magnesium (SDRM), editor search , and professor at
in chief of
Magnesium Re-
Vincent de Paul Hospital in
done extensive reviews of ongoing magnesium
Paris, has
research. 24
St.
Development of Research
’
25
Magnesium
longer need to
sit
on the
researchers
agree
sidelines or reserve
the benefits of magnesium;
we need
know, now.
42
to
that
we no
judgment on
implement what we
PART TWO Magnesium-Deficient Conditions
CHAPTER Anxiety, Pain,
3
and Magnesium
for Athletes
THREE THINGS YOU NEED TO KNOW ABOUT MAGNESIUM, ANXIETY, AND DEPRESSION 1.
Magnesium
deficiency can produce
symptoms
of anxi-
ety or depression, including muscle weakness, fatigue,
eye twitches, insomnia, anorexia, apathy, apprehension, poor memory, confusion, anger, nervousness, and rapid pulse. 2.
Serotonin, the “feel-good” brain chemical that
by Prozac, depends on
magnesium
is
boosted
for its production
and function. 3.
Magnesium supports our adrenal overworked by stress.
45
glands, which are
The Miracle of Magnesium
Each year millions of people
are introduced to the
merry-
go-round of psychiatric drugs and psychological counseling for
symptoms
that
may
in fact be rooted in
magnesium
ciency. Additional millions try unsuccessfully to their
problems by turning to alcohol,
cope with
street drugs,
addictive behavior to suppress their pain.
We
defi-
and other
are a nation
suffering a 32 percent incidence of anxiety, depression,
and drug problems. Social epidemiologist Myrna Weiss-
man
at
Columbia University reports
that
more and more
Americans are becoming depressed, getting depressed
younger
age,
at a
and experiencing more severe and frequent pe-
riods of depression.
Each generation born
in the twentieth
century has suffered more depression than the previous one, and since
has
World War
more than doubled.
1
’
2
A recent study in the Archives of
General Psychiatry showed
women from
the overall rate of depression
II
a
doubling of depression in
1970 to 1992, with the use of psychiatric drugs
skyrocketing as a
result.
Children are not immune: Ameri-
can schoolchildren today are taking four times psychiatric medications as in
all
as
many
of the rest of the world
combined. 3 People do not get anxiety, panic attacks, or depression because they have a deficiency of Valium or Prozac.
Our
bodies do not require these substances for essential metabolic processes. cal
However, we can develop
symptoms because
thing our bodies
do
a
myriad of psychologi-
of a deficiency of magnesium, somerequire.
Does
it
make any
sense to
merely switch our addictions from sugar, alcohol, drugs, and
46
Anxiety, Pain,
and Magnesium
cigarettes to prescription medication
for Athletes
without looking
possible underlying metabolic causes? Psychiatrists
often rely
on prescription drugs
at the
all
too
for suffering patients and
have no insight into the metabolic functions of the mind and
body and what happens when
nutrients are deficient. Anxi-
ety and depression are often nutrient deficiency diseases and
chemical
sensitivities,
not drug deficiency diseases.
Darcy had driven across for years, so
a
mile-long bridge every day
why one morning
though she would die ing and her heart
if
did she suddenly feel as
she didn’t pull over? She was sweat-
was pounding; she
felt
sick to her
stomach
and couldn’t get her breath. What was happening to her? Fortunately, she had her cell Sara,
who
phone and
called her best friend,
helped her calm herself and breathe her
way
across the bridge safely. Later, while talking with Sara to try to
on
make
sense of the episode,
a liquid protein diet for a
that
it
Darcy
said she
had been
few weeks. Sara pointed out
could have thrown something out of balance, and she
reminded Darcy that she had warned her of the dangers of this
type of
diet.
The two women reviewed Darcy had been taking that she
list
of supplements that
as part of the
program and found
the
had neglected to take the magnesium that had been
suggested. Sara grabbed a natural health encyclopedia and, sure enough,
magnesium deficiency was
listed as
one of the
possible causes of panic attacks. If
Sara had read further, she
would have found
body demands more magnesium when on
47
that the
a liquid protein
The Miracle of Magnesium
and that the dangers of such
diet
mented
for decades
4 .
a diet
have been docu-
By eating only protein, which
magnesium, Darcy had
set herself
up for
has
little
a terrifying attack.
Fortunately, she discovered this before pursuing a prescription for a tranquilizer to deal with the frightening
toms of panic
symp-
attack.
Lack of magnesium may not have been the only cause of Darcy’s panic attack.
Her
have led to hypoglycemia. low, the
body
reacts
with
high-protein diet could easily
When
blood sugar (glucose)
is
a surge of adrenaline to bring
glucose levels back to normal, in order to keep this essential nutrient fueling the brain. Adrenaline acts to speed the heart
and retrieve glucose from
Sometimes people
liver storage.
perceive a normal adrenaline rush as a panic attack. Interestingly enough,
magnesium
is
also
required for blood
sugar control.
Women tend to pay attention to their feelings symptoms such
pret
as panic attacks as signs of
imbalance, for which they seek support. get,
however,
is
and
inter-
emotional
The support they
often in the form of a prescription for an
antianxiety drug instead of sound advice to eat a better diet, exercise,
and take the right balance of supplements.
Magnesium
deficiency can be an underlying cause of
anxiety and depression, as determined in several clinical trials
5 .
Symptoms
anxious sion,
behavior,
of chronic
magnesium deficiency include
hyperemotionality,
poor memory, confusion,
48
apathy,
apprehen-
anger, nervousness, muscle
Anxiety, Pain,
and Magnesium
for Athletes
weakness, fatigue, headaches, insomnia, light-headedness, dizziness, nervous
fits,
the feeling of a
lump
in the throat,
im-
paired breathing, muscle cramps (including leg cramps), a tingling or pricking or creeping feeling pulse, chest pain, palpitations,
on the
skin, rapid
and abnormal heart rhythm
6 7 .
’
ANXIETY Stress
so prevalent in our daily
is
desensitized to
which
is
to slow
ated
when
such
as
is
it
life
and the message
down. Anxiety
is
it
that is
we
have become
trying to give us,
a chemical reaction cre-
the adrenal glands respond to a stressful event,
low blood
very useful
if
by
releasing adrenaline. Adrenaline
you’re trying to escape from a dangerous
situation, because
the heart starts
sugar,
it
gives
pumping
you
that fight-or-flight response:
faster; digestion
slows down; en-
ergy stores are released from the liver and made available to the heart, lungs, and muscles; and the muscles of the arms
and
legs are activated. All of these responses require
sium. So each time
magnesium
we
experience any kind of stress, our
stores are tapped to create energy. This
sium depletion
magne-
itself stresses
the body,
panic attacks, which equals yet
more
which can stress.
magne-
result in
Not only do
our overworked adrenals cause magnesium depletion, but even more adrenaline
sium
levels are
ritable,
low
is
released under stress
when magne-
in the body, leaving people feeling ir-
nervous, edgy, or even ready to explode.
49
It’s
the
The Miracle of Magnesium
proverbial catch-22. 8
To put an end
to anxiety,
magnesium
needs to be replaced.
During
stress reactions,
late the release
calcium
of adrenaline.
A
is
also required to stimu-
calcium excess, however,
magnesium
causes a flood of adrenaline. Sufficient buffer excess calcium and keep
within normal
it
Magnesium
iting the stress response.
is
will
levels, lim-
important because
it
naturally diminishes the excitability of the nervous system
and lowers the
level of
calcium around nerve
function of magnesium
is
and other stress-induced
illness. 9
cells.
This
also significant in heart disease ’
10
CHRONIC STRESS According to Hans for his
work on
pleted
when
Canadian doctor famous
Selye, the
stress in the 1960s,
the
body
flight reaction to
a
shifts
from
magnesium
is
also de-
a short-term fight-or-
chronic stress reaction. The adrenal
glands produce cortisol, a type of cortisone, and another stress
hormone, norepinephrine,
also causes
magnesium
Chronic
stress
threatened, or als,
that acts like adrenaline
and
depletion.
can come from feeling insecure and
from exposure
to toxic chemicals,
heavy met-
or even loud noise, which assaults the nervous system
and overworks the immune system. For example, constant loud noise in an industrial
work
cant increase of total serum
magnesium
50
setting
induced
(as
a signifi-
magnesium was
Anxiety, Pain,
released
from
tissues)
and Magnesium
and significantly increased urinary
magnesium
excretion of magnesium, indicating a
which
for Athletes
deficiency,
lasted for forty-eight hours after exposure. 11
MAGNESIUM-DEFICIENT KIDS adults
who
can
magnesium-deficient
diets.
Our
It’s
ble
not just
when
anxious
because
of
children are also suscepti-
foods are magnesium-deficient
favorite
their
get
hot dogs, pizza, and soda. The stress in their
lives
—from
peer pressure, academic and athletic performance pressures,
worries about
body image,
the changes
and hormonal
fluctuations of puberty, exposure to negative events and
violence through the media
underdiagnosed when
it
—
also contributes. Children are
comes
to
magnesium
deficiency,
but can have magnesium deficiencies for the same reasons
as
adults. Attention deficit hyperactivity disorder
(ADHD),
and childhood depression
are associ-
juvenile delinquency,
ated with
magnesium
tions can be caused
deficiency,
by
it.
12
and some say these condi-
Instead of reaching for Ritalin or
Prozac for kids, consider whether they’re getting enough
magnesium
first.
Leo Galland, author of Superimmunity for Kids
Dr.
speculates that hyperactive children need extra
due to
ple,
magnesium
their constantly high adrenaline levels. Dr.
recommends 240
mg
6
mg
for a
,
Galland
per pound of weight per day (for exam-
40-pound
child).
51
Because magnesium
is
The Miracle of Magnesium
hard to find in a form suitable for young children, he suggests
1
tbsp of
magnesium
citrate a
day or IV2
tsp of milk
much
of magnesia a day. These are both laxatives in
larger
doses, but in such small doses they supply the necessary
nesium without
mag-
a laxative effect. 13
SEROTONIN, MAGNESIUM, AND DEPRESSION You may be
familiar with serotonin, the body’s natural
“feel-good” brain chemical.
Magnesium
serotonin story because
a necessary contributor for re-
lease
it is
is
and the uptake of serotonin by brain
amounts of magnesium, nature makes
important in the
cells.
With proper
sufficient serotonin
and you experience emotional balance. But when pletes
magnesium,
a vicious cycle spins
depression can occur. to release
stress de-
out of control, and
The body needs magnesium
order
in
and bind adequate amounts of serotonin
in the
brain.
The pharmaceutical industry has focused for the treatment of depression
on
research
its
selective serotonin reup-
take inhibitors (SSRIs) such as Prozac to capitalize
on
tonin’s chemical effects instead of giving serotonin really needs
—magnesium. SSRIs create
levels of serotonin in the
theoretically causes
mood
what
its
breakdown
lingers longer in the brain
elevation. This
posed to happen, but everyone has
52
it
artificially elevated
body by preventing
and elimination; serotonin
sero-
is
what
is
and sup-
a different reaction to the
Anxiety, Pain,
and Magnesium
for Athletes
manipulation of their brain chemicals. For some people, prolonged, rising levels of serotonin can liberate them from a
long depression. For others, the drug can lead to anxiety
and
irritability.
moods
tened
Another group of people tend
in
to have flat-
which they can neither weep nor laugh,
keeping them from the extremes of depression or mania but relegating
them
to a one-dimensional
life.
This was Maggie’s situation. She was on Prozac and desperately trying to
come
off
it
because she was unable to
cry or experience real emotions. Maggie was
down
to one-
quarter of a tablet but was afraid to stop in case her depression
came back. She
also
had high blood pressure, high
cholesterol, periodic muscle cramps,
and constipation.
I
asked her to have her magnesium tested, and her cardiologist said
it
was normal; he
said she didn’t
need magnesium
but should continue to take her five prescription medications to control her
symptoms. She
thought her muscle cramps were leg.
We
called
me when
major blood
a
her G.P.
clot in the
didn’t have time to ship a blood sample to the lab
that performs ionized
her to take 300
Doppler scan
mg
of
magnesium
testing, so
magnesium twice
a
to rule out blood clots.
I
encouraged
day and go for
a
Fortunately, the
scan was negative, so Maggie was able to avoid several
more medications
to treat
blood
clots,
was already working
to
two weeks Maggie was
also off the
relieve
again.
53
and the magnesium
her symptoms. Within
Prozac and able to cry
The Miracle of Magnesium
TREATMENT FOR ANXIETY AND DEPRESSION DIET Avoid food additives,
artificial
Eat a whole-foods diet
sweeteners, sugar, and wheat.
— organic,
if
possible
—and avoid
processed and junk food.
SUPPLEMENTS
mg twice
Magnesium: 300 Calcium:
800-1,000 mg
B complex: 5-50
mg
a day
daily
per day (derived
whole or
in
in
part
from natural sources such as brewer's yeast, wheat
germ, or
liver)
5-hydroxytryptamine:
50-100 mg
meals, three times a day
an
half
(this is
an amino acid that
crosses the blood-brain barrier and verted into serotonin;
it
hour before
is
naturally con-
has the same action as Prozac
but no side effects) St.
John’s wort:
300 mg
of standardized
extract three
times a day
SLEEP AIDS Melatonin:
2-3 mg one hour before bedtime
5-hydroxytryptamine:
50-200 mg, one
half
hour before
bedtime, on an empty stomach
Hops, valerian, and skullcap herbal combinations: one or
two 500
mg
capsules before bedtime
54
and Magnesium
Anxiety, Pain,
for Athletes
STRESS RELEASE Exercise
is
excellent for both anxiety and depression
(try
yoga, walking, biking, Pilates, swimming), as are meditation, long baths, journal writing,
dom
Techniques
(EFT,
and Emotional Free-
information available at
www.
emofree.com).
Because depression can be so debilitating, even threatening,
I
understand
measures to combat
ways work. The
why
doctors feel
it
life-
requires strong
but these strong measures don’t
it,
alternative that
the nutrient connection.
many
Magnesium
al-
doctors are missing
deficiency
is
is
a potential
cause for every type of depression. All treatment protocols
should begin with adequate doses of
this valuable
mineral
14 .
RAYNAUD’S SYNDROME Sally
had
terrible leg
cramps. During the night, her legs
jumpy and twitchy and kept her awake. muscle cramps
in her calf
If
she did
would wake her
diagnosed her
as
asleep,
up. In addition
her fingers began turning white, blue, and red. ternist
fall
felt
A young in-
having Raynaud’s syndrome, a
cir-
culatory condition caused by the spasm of tiny arteries, especially in the hands
and
Raynaud’s syndrome
feet.
may
occur suddenly or
55
as a result
The Miracle of Magnesium
of other chronic illnesses such as connective tissue disease,
trauma, or pulmonary hypertension, in which cases called
Raynaud’s phenomenon. Raynaud’s syndrome
mostly
in
young women and Cold
extremities.
is
tack. Besides the
pain, especially
may
can also play
stress
who
have
to hours.
bringing on an
a role in
at-
noted color changes there can be agonizing
when
the fingers are rewarming.
this
condition just put up with
drug treatment for
it
Symptoms
common. Many peo-
consult their doctors for a diagnosis, there tive
seen
damage of the
from minutes
last
of tingling, numbness, and burning are ple
is
often the only stimulus that initiates the
blood vessel spasms, which
Emotional
rarely leads to
is
it
it.
Even
no
is
if
they
safe, effec-
(sometimes calcium channel block-
ers are used).
the
Fortunately, Sally’s internist
knew
most
both muscle cramps and
effective treatment for
Raynaud’s because
and minimizes 300
and
He
put her on magnesium,
a daily multiple
a day.
took three months for the Raynaud’s to respond, but
Sally couldn’t believe
how good
she
The muscle cramps improved within that she cally
vitamin and mineral;
two months he added calcium, 500 mg twice
It
is
improves circulation, stops spasms,
stress reactions.
mg twice a day,
after
it
magnesium
that
had thought were
a
felt in
week, and symptoms
just part of getting old dramati-
improved. Her energy increased
sleep better.
the meantime.
was
able to
more
regular,
as she
Her bowel movements were
also
and she was much calmer than she had been
in a long time.
Nutritional recommendations for Raynaud’s include
56
Anxiety, Pain,
and Magnesium
for Athletes
liver-cleansing foods such as beets, dandelion greens, bur-
dock
and lemons, and foods rich
root,
in
magnesium,
in-
cluding nuts, seeds, green vegetables, and whole grains. Foods to avoid or reduce to lessen the
syndrome include meat, fried,
symptoms
of Raynaud’s
alcohol, spices, and fatty, rich,
or salty foods.
TREATMENT FOR RAYNAUD’S Magnesium: 300 Calcium:
500 mg
mg
twice per day
twice per day
Vitamin E as mixed tocopherols:
Evening primrose Vitamin B 3
:
oil:
100 mg
800
III
6 capsules per day three times a day (this vitamin some-
times causes the body to flush, as
it
increases circu-
lation to the extremities)
Quercetin
(a bioflavonoid):
500 mg
per day
MAGNESIUM AND MUSCLE
PAIN
A patient came for a consultation and wanted a total body X ray because she was having such severe episodes of pain her whole
body would go
must have
cancer.
I
into
spasm
—that she thought she
asked her to try taking 300
mg
of
mag-
Within three days she no longer
nesium three times
a day.
had the spasms, and
after three
57
weeks she was
free of pain.
The Miracle of Magnesium
THREE THINGS YOU NEED TO KNOW ABOUT
MAGNESIUM AND MUSCLE PAIN 1.
Magnesium helps muscles
2.
Magnesium eliminates spasms.
3.
Magnesium
relax.
relaxes blood vessels
in
the fingers to treat
Raynaud’s syndrome.
Although
shown
this patient did
not have cancer, research has
that even the pain of cancer can respond to
magne-
sium. Cancer sometimes metastasizes into nerve bundles lo-
may
cated in the neck or lower back and
even the strongest analgesics such special receptor site called
creating this type of nerve pain;
morphine. There
as
NMDA
that
is
analgesic effects
is
a
responsible for
magnesium blocks
ceptor. In cases of severe pain, intravenous
shown very powerful
not respond to
this re-
magnesium has
15 .
MAGNESIUM AND EXERCISE Cells use energy packets called phate),
Some
which
of the
are
first
ATP
(adenosine triphos-
formed under the influence of magnesium. studies
showing the relationship between
magnesium and physical performance were done on animals and found that decreased exercise capacity can be an early sign of
magnesium
deficiency.
When
58
the animals
were given
Anxiety, Pain,
and Magnesium
for Athletes
THREE THINGS YOU NEED TO KNOW ABOUT MAGNESIUM AND EXERCISE 1.
Magnesium reduces
acid,
lactic
which causes post-
exercise pain. 2.
Magnesium
is
3.
Magnesium
deficiency
in
lost during exercise.
may cause sudden
cardiac death
healthy athletes.
magnesium dissolved
Most human
in water, their
endurance was restored.
studies also confirm that both brief and ex-
tended exercise deplete magnesium.
One
of the
most amazing
neuromuscular system
is
that
effects of it
though the mineral generally stimulant. level will
If
you
magnesium on
the
provides more energy, even
acts as a relaxant
are magnesium-deficient,
and not
a
your energy
be low because you aren’t producing the necessary
energy to run your body.
When you
start taking
magne-
sium, your energy level goes up. Magnesium’s interactions
with calcium help keep calcium from causing excessive muscle contraction.
in
all
ing
Excess calcium causes tension and tightness
the muscles of the body, but
amount
when you
take a balanc-
of magnesium, this tension releases within hours,
days, or weeks, depending
nesium deficiency Exercise
is
in
on the underlying
level of
mag-
your body.
often prescribed therapeutically for anxiety
59
The Miracle of Magnesium
and depression
—to burn
off steam (so to speak), to increase
the circulation, and to get adrenaline pumping.
allows the
body
burn
to
fuel
Magnesium
and create energy
in
an
effi-
cient cycle during exercise that does not lead to lactic acid
who
production and buildup. For some individuals excessively or suffer
from chronic
amounts of lactic acid build up
fatigue
syndrome, painful
making
in their muscles
an unpleasant experience. Exercise
cise
exercise
itself
exer-
places stress
on
your body, to which your adrenal glands respond by pump-
which
ing out adrenaline,
and binds to
interacts
cell
mem-
branes in the presence of adequate magnesium.
Heavy build
up
exercisers, especially long-distance runners, can
and suffer shin
lactic acid
splints
but they keep on running because they
cles,
’
in their
just can’t
be ad-
they reach “the
feels like
something you
break through, but you keep on pushing, and sud-
denly you get the
workout. The wall
may
when
dicted to the adrenaline rush they get
wall
and painful mus-
power
mum. Yet when you
a burst of adrenaline
of your adrenal glands
and you’re
flying. That’s
when pushed
that stress-induced high
is
to the maxi-
followed by a crash,
don’t repair the damage to your adrenal glands
with good nutrition and restore the magnesium that was lost
during exercise.
Many
studies
have shown that magnesium supple-
mentation enhances the performance and endurance of long-distance runners, cross-country skiers, cyclists, and
swimmers. cise
It
aiso reduces lactic acid buildup
cramps and pain. Since
athletes
60
and postexer-
undergo severe physical
and Magnesium
Anxiety, Pain,
for Athletes
stress as well as the psychological drive to
gest suboptimal
to
win, and most in-
amounts of magnesium, they
are vulnerable
magnesium deficiency 16 .
Years ago the coach of a Florida high school football
team was concerned about
his players’ frequent
them
of leg cramps, so he gave
a
complaints
calcium supplement on a
very hot day before a rigorous game. Early in the second half,
eleven players became disoriented and had difficulty
walking. Their speech was slurred, they complained of muscle
spasms, and they were breathing very deeply. Within an
hour, eight of the boys collapsed into full-blown seizures;
two had repeated
seizures.
Those having the worst symp-
toms had been playing the hardest. Thirteen more players reported headaches, blurred vision, muscle twitching, nausea,
and weakness
what happened
17 .
Eventually
all
the boys recovered, but
to create such a frightening scene in this
group of healthy young men? Consider the that
were affected had
deficient fast-food
and
fats,
creased
all
eaten a pre-game magnesium-
meal consisting mainly of carbohydrates
and sodas containing phosphoric
magnesium
loss
acid.
With the
driven dangerously low
in-
from excessive sweating plus the
calcium supplement, their magnesium stores
Magnesium
Those
facts.
had been
18 .
deficiency
cardiac death syndrome,
may
also play a role in
which can
affect athletes
sudden 19 .
In a
study of young, healthy, well-conditioned men, strenuous effort
was reported
to give rise to persistent
magnesium
deficiency and a related long-term increase in cholesterol,
61
The Miracle of Magnesium
triglycerides,
and blood
sugar. This study postulates that
the sudden death of athletes and other intensely training individuals during extreme exertion
is
triggered
by the
detri-
mental effects of persistent magnesium deficiency on the cardiovascular system
20 21 ’
.
MAGNESIUM SUPPLEMENTS FOR EXERCISERS AND ATHLETES Dr. Seelig, cialist,
least
an internationally recognized magnesium spe-
recommends
that athletes
6-10 mg/kg/day
(or 2.
in
training obtain
at
7-4.5 mg/lb/day) of magne-
sium to help replace the losses from exertion, sweating,
and
stress.
For a
220-pound man:
600-1,000 mg
For a
150-pound woman:
400-680 mg
These doses can be cut by 150
mg
for
62
per day
people
cise moderately (one to two hours a day).
per day
who
exer-
CHAPTER Migraines, Strokes,
4
Head
Injury,
and Brain Surgery
THREE THINGS YOU NEED TO KNOW ABOUT MAGNESIUM AND THE BRAIN 1.
Magnesium
protects the brain from the toxic effects of
chemicals such as food additives. 2.
Magnesium and
is
a blood thinner, keeping thickened blood
tiny clots
from causing blood vessel spasms and
pain. 3.
Magnesium
relaxes
head and neck muscle tension that
makes migraines worse.
Martha knew and wavy
that a migraine
lines
was looming when the sparks
appeared before her eyes. Working became
63
The Miracle of Magnesium
impossible, and she
knew
would be looking
she
at the loss
of at least one day to a severe migraine attack. Medications
such
as
codeine and ergotamine had not helped her over the
years, instead
headache
making her
finally passed.
feel
And
drugged and
tired after the
new
drugs Imitrex,
the fancy
Depakote, and Midrin did nothing for her head pain but did give her chest pain and
make her more
Martha could do was
All
lie
in a
sick to her stomach.
darkened room with
a cool
cloth over her eyes, too nauseous to eat. This time, however,
instead of trying to keep hydrated with lots of diet soda, as
she usually did, she was going to drink mineral water with
lemon and natural
fruit juice.
Marthas daughter Mary,
a nurse,
had told her that
aspartame, the sweetener in diet soda, causes headaches. Even
though Martha loved her
on
average, she
knew
diet pop, drinking
two
she had to try to stop these headaches,
both the daily ones and the one or two migraines
Over
the next
day
liters a
a
week.
few days, Marthas skin itched and she was
nauseous, dizzy, and depressed. She thought she was having a
hangover reaction to the medication she had taken for her migraine, but
Mary
was going through aspartame
told her she
withdrawal. She was also having strong cravings for her diet soda, but
search
Mary
insisted that she stay off
on aspartame and how
it.
Mary
did
some
re-
and
to cope with withdrawal
brought her mother a bottle of magnesium oxide supplements.
The 500 mg twice
a
day seemed to help
the next week, Martha’s head
and
less achy.
felt clearer;
right away.
she was
more
By
alert
She hadn’t even realized that her joints and
64
Migraines, Strokes, Head Injury, and Brain Surgery
muscles had been tight and sore until she no longer had the
symptoms. To her partame from her
great relief, diet,
two weeks
after eliminating as-
she realized that she hadn’t had one of
those headaches that she used to get daily. After of strictly avoiding aspartame, she
still
two months
had no more headaches
or migraines, except once after she had eaten something she
had not
known
contained
artificial
sweetener. That con-
vinced her even more that, for her, aspartame was poison.
ASPARTAME AND MSG: EXCITOTOXINS Aspartame
is,
in fact, an excitotoxin,
substances, usually acidic
amino
one of
a
acids, that in high
group of
amounts
react with specialized receptors in the brain, causing de-
struction of certain types of neurons.
A growing number of neurosurgeons and neurologists are convinced that excitotoxins play a
ment of
critical role in
the develop-
several neurological disorders, including migraines,
seizures, learning disorders in children,
and neurodegen-
erative disorders such as Alzheimer’s disease, Parkinson’s disease, rosis
Huntington’s disease, and amyotrophic
(ALS).
amino
1
Glutamate and aspartate are two important
acids that act as neurotransmitters in the brain in
very small concentrations, but they are also able in food additives.
and
in
lateral scle-
Glutamate
is
in
commonly avail-
MSG, a flavor enhancer,
hydrolyzed vegetable protein, found in hundreds of
processed foods. Aspartate
is
one of three components of
aspartame (NutraSweet, Equal), a sugar substitute. In higher
65
The Miracle of Magnesium
concentrations as food additives, these chemicals constantly stimulate brain cells and can cause
process of
cell
known
death
them
undergo
to
a
as excitotoxicity; the cells are
excited to death.
HYPOGLYCEMIA The
brain becomes extremely vulnerable to excitotoxins
during episodes of low blood sugar or hypoglycemia.
Pound
for
pound, the brain uses more blood sugar than any
other part of the body.
nourished people and curs in individuals can't
mount
sugar
when
Low
blood sugar occurs
when people
skip meals.
whose adrenal glands
It
in mal-
also oc-
are depleted
and
the necessary adrenaline response to raise blood it
Magnesium
gets too low.
is
responsible for
balancing blood sugar. With sufficient magnesium and bal-
anced meals to prevent low blood sugar, you can protect yourself against headaches, attention deficit hyperactivity disorder,
mood
disorders, and even premenstrual tension.
Supporting the brain
and
a safe
as
much
as possible
environment, you
may
with safe nutrients
never need the brain-
altering medications that are prescribed for these disorders.
Medically,
hypoglycemia occurs when blood sugar
(glucose) drops to a
80-110 mg/dl).
If
you
white sugar and white
low of 50 mg/dl (normal eat a highly refined diet flour,
is
about
with
lots of
foods whose carbohydrates are
rapidly absorbed into the bloodstream, your blood sugar will
quickly become elevated;
when
66
it
reaches a certain
maximum,
Migraines, Strokes, Head Injury, and Brain Surgery
insulin enters the bloodstream
away
glucose
sugar to drop. insulin
and quickly ushers the excess
into the cells of the body, causing
The more sugar you
released and the quicker
is
eat
your blood
and absorb, the more
your blood sugar can
fall.
This abrupt drop causes adrenaline to be released from the adrenal glands to fall
make
you
so low that
sure that the blood sugar does not
faint.
When
that adrenaline mobilizes
the sugar stores in the liver to elevate your blood sugar,
however,
it
also
may
give
even
feel like a
you
produces a fight-or-flight reaction, which
a sense of anxiety or
impending doom.
It
may
panic attack because you don’t equate your
symptoms with low blood
sugar.
At
this point,
if
you
something to pick you up or comfort you, such
as a
bar or an aspartame-containing diet drink, or
if
eat
candy
you
are
exposed to other environmental toxins, your glucosedeprived, magnesium-deficient brain will be ble to the effects of the excitotoxins.
more vulnera-
Many
diseases of
the nervous system are being associated with excitotoxin
buildup in the brain, including migraines, seizures, strokes,
and brain If
injury.
you have magnesium
aspartame, the toxicity aches and migraines.
is
deficiency and regularly use
magnified and can result in head-
You can
easily identify
whether your
headaches are caused by aspartame: Give yourself sixty days
without any aspartame and judge for yourself.
want
to
minimize the withdrawal
effects, take
And 150
if
you
mg
of
elemental magnesium three to four times a day (see page 71 for
more on
dosages).
67
The Miracle of Magnesium
Magnesium
helps prevent the chain of events that causes
death due to low blood sugar and exposure to other tox-
cell
ins besides excitotoxins.
protectants
One
of the most important neuro-
known, magnesium helps defend our
cells against
potential neurotoxins in our environment, such as pesticides, herbicides, food additives, solvents,
and cleaning products. 2
Drs. Michael and
Mary Dan
Power
they had only one supplement to give
,
state that
if
their patients, they ers. 3
would choose magnesium above
In Chapter 10
ins to
which we
avoid them, and
Fades, authors of Protein
we
will talk
more about
on
are subjected
how magnesium
oth-
all
the myriad tox-
a daily basis,
how we
can
can protect us from harm.
MIGRAINE MECHANISMS Twenty-five million Americans suffer from migraines. Statistically,
women
have more migraines than men, especially
The following biochemical
in the twenty-to-fifty age group.
events involving
low magnesium have been
graine sufferers and
•
may
set the stage for migraines. 4
In nonmenopausal
women,
estrogen rises before the
period, causing a shift of blood
and muscles. As
identified in mi-
a result,
magnesium
magnesium
into
bone
levels in the
brain are lowered. •
When magnesium
is
low,
it is
unable to do
its
job to
counteract the clotting action of calcium on the blood. Tiny blood clots are said to clog up tiny brain
68
Migraines, Strokes,
blood
Head
Injury,
and Brain Surgery
vessels, leading to migraines. Several other sub-
stances that help create blood clots are increased
when magnesium •
Low
is
too low.
magnesium promotes neurotransmitter
brain
hyperactivity and nerve excitation that can lead to
headaches.
Several conditions that trigger migraines are also associated
with magnesium deficiency, including pregnancy, alcohol take, usage of
Magnesium
•
some
diuretic drugs, stress,
deficiency
Magnesium dilate,
is
and menstruation.
many ways.
related to migraines in so
relaxes
in-
blood vessels and allows them to
reducing the spasms and constrictions that can
cause migraines. •
Magnesium mitters
regulates the action of brain neurotrans-
and inflammatory substances, which
play a role in migraines •
Magnesium
when
thins the blood,
may
unbalanced.
somewhat
like aspirin,
preventing the formation of tiny clots that can block
blood vessels and cause pain. •
Magnesium
relaxes muscles
and prevents the buildup
of lactic acid, which, along with muscle tension, can
worsen head
pain.
A group of three thousand patients given 200 mg of magnesium daily had an 80 percent reduction
symptoms. 5 This study did not have
69
in their migraine
a control group, so the
The Miracle of Magnesium
results
could be questioned, but
and triggered
it
aroused a lot of excitement
a flurry of research
on magnesium and mi-
A great deal of that research was done by Dr. Alexander Mauskop, director of the New York Headache Center, graines.
working with Drs. Bella and Burton Altura, who have been studying migraines and migraine treatments for about ten years. Their research is
team consistently found that magnesium
deficient in people with migraine
and many other types of
headache; treating the deficiency alleviates the headache. Dr.
Mauskop with
studies using sensitive
one of the
the Drs. Altura undertook
magnesium ion
electrodes. 6
many
During
they found a deficiency in magnesium ions
first
but not total serum magnesium in migraine patients. 7 Migraine sufferers with
given intravenous viation of their
low magnesium ion
magnesium experienced
symptoms, including
levels
a
who were
complete
alle-
sensitivity to light
and
sound. 8 Subsequent studies of migraine patients confirmed a
common
pattern and support a role for
ciency in the development of headaches. 9
magnesium
The
found that infusion of magnesium resulted
defi-
researchers
in a rapid
and
sustained relief of acute migraine. Because of an excellent safety profile
and low
cost,
they
recommend
sium supplementation for migraine 6
oral
magne-
sufferers at a level of
mg/kg/ day. 10 Patients with cluster headaches, a very severe
form of
recurrent headache, have also been reported to have low
magnesium ion
levels.
Some people
suffer
bouts of pain daily in a siege that can
70
up
last
to
twenty
for months.
Migraines, Strokes, Head Injury, and Brain Surgery
Another study from Altura, Altura, and Mauskop examined the possibility that patients with cluster headaches and
low magnesium ion infusion of
levels
magnesium
may respond
sulfate.
Within
to an intravenous fifteen
minutes of
an intravenous dose of magnesium, nine patients with cluster
had
headaches
Blood ionized magnesium
testing thus proves to be useful
in elucidating the pathogenesis of cluster
who may
identifying patients
magnesium, much
as
it
benefit
headaches and in
from treatment with
does for migraines. 12
Another research team
treated eighty-one patients with
ongoing migraine headaches with 300
The frequency
twice a day.
aborted. 11
headache
acute
their
mg
of migraines
of
magnesium
was reduced by
MIGRAINE TREATMENT may
Identify food allergies that
Magnesium: 300 Calcium:
500 mg
mg one
to
trigger migraines
two times per day
twice per day
Vitamin B 2 (riboflavin): Vitamin B complex:
400 mg
50 mg
per day
per day
(it is
the complex to prevent imbalances large
amounts
of
necessary to take if
you are taking
one B vitamin)
Feverfew Tanacetum parthenium): (
Stress therapies
Regular exercise
71
100 mg
per day
The Miracle of Magnesium
v
has been used to treat headaches
Aspirin
Magnesium-buffered
for
aspirin, however, is preferred by
some
Could magnesium be responsible for
users.
beneficial effects?
used
aspirin
in
decades.
heavy of
its
The same question applies to buffered
heart disease.
41.6 percent in the
magnesium group but by only
cent in a control group that received placebos.
15.8 per-
The number
of migraine days and drug consumption for pain also de-
creased significantly in the
magnesium appears
oral
magnesium group. High-dose
to be effective in migraine treat-
ment and prevention. 13 In Dr. Mauskop’s
What Your Doctor May Not
You About Migraines he outlines migraines.
and
a
It
his “triple
includes magnesium, vitamin
B2
Tell
therapy” for (riboflavin),
well-known migraine herb, feverfew.
HEAD INJURY, BRAIN SURGERY, AND STROKE Magnesium does much more than any drug
to protect the
blood circulation and the brain:
•
It’s
•
It
a vasodilator,
opening up blood
vessels.
protects the endothelium, or inner layer of blood
vessels.
72
Migraines, Strokes,
•
It
Head
Injury,
and Brain Surgery
closes the calcium channel to excessive calcium
influx.
MAGNESIUM-DEFICIENT BRAINS With most of the U.S. population
many Americans
deficient in
magnesium
14 ,
are at greater risk for a host of serious
problems, including stroke with severe poststroke complications,
depending on the degree of magnesium deficiency;
poor recovery from head injury with escalating neurological
damage; neurotoxin damage from vast numbers of
chemicals in our
food, and water: seizure disorders;
air,
Alzheimer’s disease; and Parkinson’s disease
15 .
These con-
ditions are the neurological equivalent of heart disease.
After
all,
both heart and brain are excitable
give off electrical energy,
The complexity
and both must have magnesium.
of the mechanisms of central nervous sys-
tem hyperexcitability due
now
tissues that
being appreciated
magnesium deficiency
to
is
only
16 .
HEAD INJURY AND MAGNESIUM Traumatic brain injury (TBI)
is
a
major public health prob-
lem throughout the world. There are more than four hundred thousand patients with TBI in the United States alone.
From fall
animal studies,
we know
dramatically at the
site
that brain
magnesium
of injury as this mineral
pleted in a cascade of events
17 .
In sixty-six
human
levels is
subjects
with acute blunt head trauma, the greater the degree of jury, the greater the
calcium-ion-to-magnesium-ion
73
de-
in-
ratio.
The Miracle of Magnesium
Such findings provide evidence of magnesium ion changes in
blood
which could be of
after traumatic brain injury,
both diagnostic and prognostic value. 18 Studies of both animals and brain trauma victims suggest that higher magne-
sium
levels are associated
sufficient
magnesium
Magnesium
will create a better healing
TBI without adverse your doctor
family
member
Ionic
if
is
is
used to
effects. 20
your child
fol-
crucial information to
is
suffers a
head injury or any
involved in a motor vehicle accident.
magnesium
makes
testing
posttraumatic headaches
much
easier.
magnesium ion concentration and magnesium-ion
outcome.
with severe
treat patients
This
Giving
edema
sulfate significantly reduces brain
lowing brain injury and
give
a better recovery. 19
with
ratio
were found
the
diagnosis
of
Abnormalities in
the
calcium-ion-to-
with post-
in children
traumatic headaches, but total serum magnesium levels
were normal. 21 Obviously, studies using only the
serum magnesium
test
would miss
the diagnosis and
to properly treat these patients. (See
discussion of
A verse.
magnesium
magnesium
deficit
from head injury
fluid, three
under the
hours to reach the deep brain Seals
skull,
is
slow to
re-
hours to reach the
and
tissues.
a full four to six
Experiments with
and marathon runners show that
of intensive training, they experience if
a full
According to Dr. Blaylock magnesium takes thirty
cortical area directly
and,
Chapter 12 for
fail
testing.)
minutes to get into the spinal
Navy
total
no supplements
after a
magnesium deficiency
are taken, the deficiency
74
month
is still
pre-
Migraines, Strokes, Head Injury, and Brain Surgery
sent three to six
your
diet
emotional,
is
months
only makes sense that
and you’re under
deficient
you need
later. It
to replace
if
stress,
physical or
your magnesium
stores daily.
BRAIN INJURY, ALCOHOL, AND MAGNESIUM Drs. Bella and Burton Altura discuss the direct cause-and-
between alcohol-induced headache and
effect relationship
and stroke. 22 They note that binge
risk of brain injury
drinking of alcohol
is
associated with an ever-growing
num-
ber of strokes and cases of sudden death, with alcohol causing vasospasm and rupture of the cerebral arteries. 23 In
animal studies, high doses of alcohol caused a rapid
magnesium ions
in levels of
of calcium, followed
in the brain
by cerebral
’
ple with mild head injury have been deficits in
magnesium
injury, the greater
sium
ions,
and an elevation
spasm and rupture
vessel
of cerebral blood vessels (stroke). 24 25 In
human
studies,
peo-
found to exhibit early
ions; the greater the degree of
and more profound the
and the greater the
fall
level of
deficit in
head
magne-
calcium ions com-
pared to magnesium ions. Patients with histories of alcohol abuse or ingestion of alcohol prior to head injury exhibited greater deficits in
magnesium ions (and higher calcium-
ion-to-magnesium-ion
ratios) and, unlike the subjects
out alcohol, remained in the hospital longer.
Data on 105 men and
stroke indicate that,
nesium ions
is
on
at least several
with-
days
women with different types
average, a 20 percent deficit in
seen, while total
normal. 26
75
serum magnesium
is
of
mag-
usually
The Miracle of Magnesium
The Alturas it
has been
also report that in other
shown
human
studies,
that migraines, headache, dizziness,
and
hangover, which accompany ethanol ingestion, are associated with rapid deficits in total
only
sium
magnesium ion
level
but not in
serum magnesium, which obscures the diagnosis total
serum magnesium
is
measured.
necessary to regulate calcium,
is
its
And
since
if
magne-
deficiency creates
calcium-induced vascular spasms and pathology. 27 Migraines
and alcohol-associated headaches can be treated with venous administration of magnesium tension headache and is
also
its
accompanied by
sulfate. 28
Premenstrual
exacerbation by alcohol in
deficits in
magnesium
intra-
women
ions and ele-
vation in the calcium-ion-to-magnesium-ion ratio. Intra-
venous magnesium
both the premenstrual
sulfate corrects
tension headache and the serum deficit in
Animal experiments show
that
magnesium
intravenous
ions.
magne-
sium can prevent alcohol-induced hemorrhagic stroke and the subsequent
fall
in brain
magnesium ion
level as well as
other metabolic factors. 29 Recent data indicate that alcohol-
induced cellular cellular
loss of
magnesium
ions
is
associated with
calcium overload and generation of free radicals;
however, pretreatment with vitamin
E
can also prevent
alcohol-induced vascular injury and pathology in the brain. 30
(Learn more about free radicals on page 193.)
BRAIN SURGERY AND MAGNESIUM During and utes
come
after brain surgery,
into play
magnesiums many
by preventing
76
attrib-
stroke, keeping calcium
Migraines, Strokes, Head Injury, and Brain Surgery
from entering damaged
cells,
and decreasing the incidence
of seizure and spasm. These favorable effects have
proven unequivocally
in
animal studies, but
ence in the neurosurgical operating efficacy as lives are being saved.
room
Many
been
all
clinical experi-
also proves
its
surgeons make
it
standard procedure to administer intravenous magnesium to
all
their surgical patients before
Horn,
a general
magnesium
an operation. Dr. Bernard
surgeon in California, has given intravenous
sulfate to
more than
over a fifteen-year period. Dr.
blood pressures
as
high
as
eight thousand patients
Horn
reports that patients’
200 over 150 would normalize
before surgery. 31
Intravenous magnesium sulfate also acts as a general anesthetic so that during surgery the dose of other chemical anesthetics can be safely reduced.
nesium
also results in
Using intravenous mag-
lower postoperative pain scores,
less
pain medication needed in the twenty-four hours after surgery, and less postoperative nausea and vomiting.
nesium
sulfate
is
Mag-
therefore a safe and cost-effective addition
to such general anesthetics as propofol, remifentanil,
and
mivacurium. 32
STROKE All deaths due to stroke cases)
among Taiwan
residents (17,133
from 1989 through 1993 were compared with deaths
from other causes (17,133 the higher the
magnesium
controls). It
was determined
levels in water, the
dence of stroke. 33
77
lower the
that inci-
The Miracle of Magnesium
THREE THINGS YOU NEED TO KNOW ABOUT MAGNESIUM AND BRAIN SURGERY 1.
Good neurosurgeons
give
magnesium
to
all
their surgi-
cal patients.
2.
Magnesium helps the
3.
Magnesium can prevent strokes
brain recover from
head
injury.
make them
or
less
damaging.
Decades of research show that withdrawal of magnesium from cerebral elevated ies
arteries causes
magnesium produces
show
that
when
in the brain, the
there
is
them
relaxation
to spasm, whereas 34 35 36
.
is
’
Animal stud-
normal or elevated magnesium
damage caused by stroke
neurological deficit
’
lessened. This
blocks calcium from flooding the
is
cells
is
reduced and the
because magnesium
and causing
injury.
Further research indicates that the area of the brain dam-
aged by stroke contains injured neurons that remain hyperactive for several hours after the stroke has occurred
These
cells are frantically
37 .
struggling to survive and need
even more oxygen, glucose, and magnesium than normal. In addition,
when
these vital nutrients are deficient, those neu-
rons become especially vulnerable to the damaging effects of excitotoxins that rush in to
fill
nutrients. Hospitalized patients
78
the void
left
by escaping
commonly have low mag-
Migraines, Strokes, Head Injury, and Brain Surgery
nesium
levels,
to survive.
which means
that neurons are even less likely
According to one researcher,
magnesium deficiency alone
is
enough
a state of severe
for rats to develop
widespread injury to their brains. 38
A
study of stroke patients in
New
York
highlights the
magnesium intervention
absolute requirement for
in the
ER.
Ninety-eight patients admitted to the emergency rooms of three hospitals with a diagnosis of stroke exhibited early
and significant
deficits in
magnesium ions
a sensitive ion-selective electrode.
demonstrated
a
The
as
measured with
stroke patients also
high calcium-ion-to-magnesium-ion
signs of increased vascular tone
ratio,
and cerebral vessel spasm. 39
DIURETICS DRY OUT THE BRAIN
An
elderly
woman’s
total
serum magnesium
level
became
depleted due to a diuretic she was taking for hypertension. 40
She was admitted to the hospital with severe weakness and developed an overt psychosis with paranoid delusions. Fortunately, her deficiency
was
identified,
intravenous doses of magnesium, her
and following large
symptoms disappeared
within twenty-four hours. She was unable to discontinue
magnesium therapy without as
long
ties
as she
was taking the
a recurrence of her diuretic.
No
symptoms
other abnormali-
were found to explain her condition. People
who
are
prescribed diuretics should check with their doctor about taking at least 600
mg
a
day of supplemental magnesium
divided doses.
79
in
The Miracle of Magnesium
MAGNESIUM AND SEIZURES The brain
is
in a state of constant electrical activity. Brain
cells are either
stimulating or suppressing activity in a deli-
These
cate push-and-pull balance.
some switches
are turned
cells are like switches:
on and some
are turned off
by
neurotransmitter chemicals. The action of these neurotransmitters could not take place without calcium, magnesium,
and
zinc,
which play various
roles in switching
on and
off
the nerve cells to electrical stimulation.
Brain
cells altered
by trauma, chemicals, or severe
can be permanently switched on and peated firing in
Magnesium
many
nerve
fire excessively.
may
shown
that
at all.
likely to
low magnesium
occur 41 .
80
reducing the
Conversely, experimental in the
cantly lowers the threshold for seizures, that
more
Re-
result in seizures.
raises the threshold for seizures,
chance of them developing studies have
cells
stress
body
is,
signifi-
makes them
CHAPTER
5
Hypertension, High Cholesterol, Spastic Heart, Angina, Arrhythmia, Arteriosclerosis,
and Heart Attack
THREE THINGS YOU NEED TO KNOW ABOUT MAGNESIUM AND HEART DISEASE 1.
Magnesium prevents muscle spasms
of
the
heart
blood vessels, which can lead to heart attack. 2.
Magnesium prevents muscle spasms
of the peripheral
blood vessels, which can lead to high blood pressure. 3.
Magnesium prevents calcium buildup plaque
in arteries,
in
which leads to clogged
cholesterol arteries.
Annette was tired of peoples shocked reaction when they learned that she was recovering from a heart attack. She
knew
that the
common
image of heart disease was that
81
it
The Miracle of Magnesium
targeted aggressive, overweight
men who smoked and
ate
too much. Annette, on the other hand, was slim, reserved,
and
who
a vegetarian
friends tried to
ate a low-fat diet.
her about the Dr.
tell
She chuckled
when
Dean Ornish
vege-
tarian diet for reversing heart disease, because she’d lived
according to that
diet.
She was only
nonsmoker, with exemplary
fifty-six, a
blood pres-
cholesterol, but she did have slightly elevated sure, her tack.
only risk
Now
factor.
Yet she had had a mild heart
at-
she suffered from daily palpitations and was on
several medications that
seemed to drain her energy more
with every passing day. She was also simply too afraid to exert herself for fear of
bringing on another heart attack.
Annette was becoming an
invalid,
and
pointment her cardiologist was shocked appearance.
urged by
sium
test.
He
The
her worn-out
at
decided to run some blood
a student
doctor to order the
results of that test
new
her next ap-
at
tests
and was
ionized magne-
were so low that the
lab
rushed the results to him the next morning. His nurse
immediately called Annette to come
in,
saying the doctor
had found something that would help her Annette was prescribed
a
feel
better.
magnesium preparation
she mixed with water (Slow-Mag) that began to
that
work
within twenty-four hours. She was amazed that her muscle aches, insomnia, palpitations,
peared. She tions.
was even
and fatigue
able to cut back
Her doctor vowed
to test
all
all
on her other medica-
his patients’
ion levels from then on, and wondered aloud
82
but disap-
magnesium
if it
had been
Hypertension, High Cholesterol, Spastic Heart, Angina
AN IMPORTANT REMINDER ABOUT TAKING
MAGNESIUM WITH PRESCRIPTION DRUGS You
may
experience a decreased need for your drugs as
magnesium
deficiency
is
corrected or as
magnesium
your symptoms or reverses your condition. the
symptoms
clear up
due
for
to the
In
treats
other words,
which the drug was prescribed may
magnesium, making the drug unnec-
essary or toxic and causing
new symptoms.
doctors should be on the alert for a shift
in
Patients and
symptoms. Be
sure to work with your doctor to lower your medication
doses
safely.
low magnesium
in the first place that
had led to Annettes
heart attack.
As we
will learn in
Chapter
familiar with the use of
women
about to
deliver.
7,
obstetricians are quite
magnesium
for hypertension in
Unfortunately, they aren’t talking
to cardiologists or even to family doctors about the impor-
tance of the
magnesium
main
one of
risk factors for heart disease.
Heart disease
women
in treating general hypertension,
is
the
number one
killer of
and men, accounting for half of
both American all
(52.3 percent of the total deaths occurring in
U.S. deaths
women com-
pared to 47.7 percent in men). According to the American
Heart Association, every thirty-three seconds someone
83
in
The Miracle of Magnesium
the United States dies of cardiovascular disease; that’s ap-
proaching one million deaths annually. Hypertension occurs in fifty million
Americans and accounts for an estimated
29.3 million office visits a year to allopathic doctors (M.D.’s)
Antihypertensive drug prescriptions are given these appointments, even though
at
most of
magnesium has been used by medical doctors,
successfully for over half a century
osteopaths, and naturopathic doctors. 2
’
3
THE SLIPPERY ROAD TO HEART ATTACK STEP ONE: LOSS OF ARTERIAL ELASTICITY The coronary
from
arteries bringing oxygen-filled blood
in-
side the heart through the aorta to the heart muscle are very, very small, only thick).
about 3
doesn't take
It
much
blood clot or to imagine
across
to plug
them
Magnesium prevents blood These coronary
mm
(a nickel is
them up
collapsing
clot formation
arteries get
mm
with a tiny
when
and
2
spasm.
in
artery
even smaller as they
spasm.
split into
two, then four, then eight and so on as they descend toward
the bottom of the heart. Each of these splits furcation. According to cardiologists, sclerotic
plaques
initially
is
called a bi-
about 85 percent of
form near bifurcations.
It
believed that the development of these plaques
sponse to
injury.
This
means
is is
widely a re-
that something, such as an
84
1
in-
Hypertension, High Cholesterol, Spastic Heart, Angina
may be damaging
fection,
and calcium building up
the arteries, rather than just fat a
like silt in
river.
Endothelial cells are a single layer of specialized cells
membrane
that form the inside
thelial layer (the next layer in) is a very thin
sue that contains
As
elastin.
its
the layer responsible for providing in
your arteries.
quires
It
magnesium
is
flow
in
sponse
much
of the elasticity
and control the
flex
is
re-
Smooth muscle
dilation of the arterial in
the
and magnesium causes
is nitric
final
oxide, which
messenger is
of the earliest signs of in
for the dilation re-
dependent on magnesium.
magnesium
deficiency
is
the subendothelium. Animals
on low-magnesium diets lose the
ity
this
which together control the blood pressure and
degeneration of elastin
terial
layer.
by the calcium/magnesium ratio
the artery. A
One
implies,
the next
body. Calcium causes contraction relaxation,
tis-
name
important to note that your body
cells are
cells provide integrity
triggered
connective
to maintain healthy elastin.
Smooth muscle
cavity,
The subendo-
of an artery.
elasticity
of their ar-
system. Coronary arteries require even more elastic-
than other arteries because they must stretch and as the heart expands and contracts. Loss of
results in inflammation of the endothelial thelial
layers
at
points
that
are
most
elasticity
and subendomechanically
challenged by stretching the bifurcations. Imagine a small
85
The Miracle of Magnesium
rubber-band-like tube shaped
grasp the two legs of the Y
hand, grip the single
leg.
like
in
a
In
Y.
your mind’s eye-
one hand. With your other
Begin pulling them apart just as
though they were stretching on the surface of the heart. Stretch If
we
it
left
as far as you can. Where the rubber tube out
what would happen
if
two
it
the shape weakest?
the sun for a
you slowly stretched
might you expect the time
in
is
first
it
week
or so,
again? Where
crack to appear? Most of the
would happen at or near where one tube becomes
—at
the bifurcation.
makes sense
If
your artery loses
that the problem might
show up
elasticity,
it
at or near the
bifurcation.
STEP TWO: THE INFLAMMATORY RESPONSE Inflammation begins with to white blood cells to heal the is
too
injury of
the artery wall, leading
and cholesterol hovering around
damage. At
this stage in the process,
much calcium and
not enough
magnesium
if
trying
there in
the
bloodstream, excess calcium precipitates around the area of inflammation
and
in
the artery wall. The area
becomes
rigid
interferes with blood flow.
STEP THREE: HEART ATTACK Over time, the above steps weaken and plug the coronary arteries
The
and slowly
final result is
kill
small areas of the heart muscle.
severe chest pain,
portion of heart muscle,
damage
and heart attack
86
4 .
to a larger
Hypertension, High Cholesterol, Spastic Heart, Angina
Some
of the
evidence for the use of magnesium
first
came from epidemiological
against heart disease
studies in
Wales, Taiwan, Sweden, Finland, and Japan showing that
death rates from coronary heart disease are higher in communities with magnesium-deficient water and magnesium-
where calcium
deficient diets. 5 Areas
in the
water
much
is
higher than magnesium or where dietary intake of calcium is
higher than magnesium
disease.
A
showed even more coronary
U.S. study done over a seven-year period fol-
lowed fourteen thousand men and that
heart
low magnesium
in the diet
may
women
and concluded
contribute to the origin
of coronary atherosclerosis and acute heart attack. 6
The Centers
for Disease Control and Prevention in At-
lanta followed twelve
the end of disease.
thousand people for nineteen years,
which 4,282 people had
died, 1,005
at
from heart
Risk of dying from heart disease was highest in
those with magnesium deficiency. Researchers servative estimate that
1
1
made
a
con-
percent of the half a million peo-
ple dying of heart disease in 1993 could have been directly related to
magnesium
deficiency. 7 If
more
accurate measure-
ments for magnesium deficiency were used, such
magnesium
testing,
we would
find the
numbers
as ionic
to be even
higher and the need for magnesium even greater.
The evidence has been mounting nesium plays sclerosis
and
a crucial role in the
arteriosclerosis. 8
’
9
for decades that
mag-
prevention of both athero-
It
maintains the elasticity of
the artery wall, dilates blood vessels, prevents calcium deposits,
and
is
necessary for the maintenance of healthy mus-
87
The Miracle of Magnesium
cles,
including the heart muscle
magnesium
One
is
critical to
itself.
For
these reasons,
all
the maintenance of a healthy heart. 10
of the pivotal metabolic chemicals in the
oxide (NO).
gen and oxygen, but
it
is
compound made from
very simple
It is a
body
nitric
nitro-
packs a powerful punch. Nitric oxide
controls vasodilation, but this activity
under the direction
is
of magnesium. 11
HIGH CHOLESTEROL The upper
limit of
normal cholesterol
is
200 mg/dl, but
it
appears that over time, with the average cholesterol in the general population
medicine accepts
becoming more
as
normal have
elevated, the values that risen.
Some
doctors are
taking a stand and revising the upper limit of normal to 180 mg/dl.
most
As with hypertension,
cases of high cholesterol
is
down
the actual cause of
said to be
unknown. High
cholesterol tends to run in families and occurs in association
with low thyroid hormone production or hypothyroidism, liver disease,
and pregnancy.
There are several types of cholesterol with different functions,
some of which we
label
good and some bad. Cho-
with high-density lipoprotein,
lesterol associated
generally considered to be beneficial to the body. ently functions to posits it
from blood
remove other cholesterol or
vessel walls
and the blood
itself,
HDL, It
is
appar-
fatty de-
bringing
to the liver for processing and excretion. Low-density
lipoprotein,
LDL,
is
commonly thought
88
to be harmful to
Hypertension, High Cholesterol, Spastic Heart, Angina
the
body because
it
carries cholesterol into the bloodstream,
promoting the buildup of cholesterol plaque on the walls.
into
Very-low-density lipoproteins,
LDLs
But
all
in the liver
made
of these cholesterols are normally found in the the high
is
cholesterol (cholesterol abnormally
we
are
and are also thought to be harmful.
body. What’s not normal
that
VLDLs,
arterial
amounts of oxidized
bound with oxygen)
eat in processed foods, fast foods,
and
fried foods.
In addition, chlorine, fluoride in water, pesticides, and other
environmental pollutants can also oxidize cholesterol in the body.
It is this
cerned about
oxidized cholesterol that researchers are con-
when
it
comes
to heart disease
12 .
Regular use
of antioxidants such as magnesium, vitamin E, vitamin A,
vitamin C, and green tea can lower oxidized cholesterol levels.
There
is
compelling evidence that magnesium therapy
reduces cholesterol levels
13 14 ’ 15 ’
,
even
when
there
risk factor present for hypercholesterolemia
There are no
yond
visible
symptoms
a genetic
16 .
of high cholesterol be-
the associated signs of a bad diet, sedentary lifestyle,
smoking, alcohol intake, and
stress.
A poor diet with a high
intake of saturated and polyunsaturated oils, fried
fats,
hydrogenated
foods, meat, sugar, coffee, and alcohol will elevate
cholesterol levels, especially
when
whole grains and vegetables. Add cholesterol increases.
The very
cholesterol also causes
magnesium
many
is
a
person lacks fiber from
a sedentary lifestyle,
diet that
and
promotes elevated
deficiency. Unfortunately,
doctors do not have the time or inclination to educate
patients about correct eating habits that could reduce their
89
The Miracle of Magnesium
cholesterol, instead using medication to treat the problem.
To be
fair,
ply even
weight
many
if
loss.
patients don’t have the inclination to
their doctor
recommends
ment, making compliance
Many
to lifestyle
more dramatic improve-
easier.
of us have been conditioned to believe that ele-
vated cholesterol
why
and
a diet, exercise,
Adding magnesium supplementation
changes, however, gives patients
com-
is
the only cause of heart disease; that
is
marketers have been so successful in getting us to re-
place the saturated fat of butter with hydrogenated vegeta-
and dental anthropologists
ble oils. Yet epidemiologists
proved long ago that various world cultures that
ate high-
cholesterol diets for thousands of years (including meat, lard,
cream, butter, and eggs) suffered very
heart disease
17 .
Almost
all
little,
the long-lived, healthy
if
any,
com-
munities where degenerative disease and heart disease were
unknown
included significant amounts of natural, unpro-
cessed meat or dairy in their diets.
once a country
is
worse list
is
it is
also clear that
exposed to refined and processed food, or
A major disadvantage tain extra
And
sugar
in
of low-fat products
is
that they con-
order to capture the taste buds. Even
aspartame, a synthetic sweetener with a daunting
of ninety-two side effects to
health, avoid both.
90
its
name. To maintain your
Hypertension, High Cholesterol, Spastic Heart, Angina
“altered” meat and “altered” dairy, health declines in a
number oils
of ways. 18
’
19 20
Hydrogenated
’
oils are
unsaturated
and for that reason were thought to be healthier than
saturated fats such as butter. But the processing of liquid
vegetable
oil
by
heat, pressure,
and chemicals to change
it
into a solid fat creates an unhealthy synthetic product called a trans fatty acid (as
Only
opposed to the natural
in the late 1990s did
we
find out that these highly re-
fined hydrogenated oils themselves
plaque
much more
than butter. In
promote fact,
that the rise of myocardial infarctions,
general, can be traced
genated
oils
were
first
atherosclerotic
some
scientists say
and heart disease
in
back to the 1930s, when hydro-
introduced.
fatty acids cause arterial
cis fatty acid).
We now know that
damage and
cancer.
Be sure
trans
to read
labels to avoid this substance.
HOMOCYSTEINURIA Dr. Kilmer
McCully was
the
first
researcher,
back
in 1969,
to identify a condition of increased levels of an
amino
acid,
homocysteine, in the urine of patients with heart dis-
ease,
which could be reversed with
Homocysteine which
in
is
a
elevated
certain nutrients. 21
amounts causes oxidized vessels. (See
page 89 for
cholesterol, a definition
of oxidized cholesterol.) For certain individuals
enzymes
become
a real
22
normal by-product of protein digestion,
which damages blood
specific
’
who
lack
for protein digestion, homocysteine can
problem.
91
The Miracle of Magnesium
NORMAL 180 mg/dl
Cholesterol:
HDL
cholesterol: greater than
LDL
cholesterol: less than
VLDL
Total-cholesterol-to-HDL less than
A
45 mg/d
130 mg/d
cholesterol: less than
mal
VALUES
LIPID
35 mg/d
I
I
men
ratio: in
3.43 (average = 4.97);
ratio is less
liter
the optimal ratio
women
in
than 3.27 (average
healthy level of homocysteine
moles per
I
=
the opti-
4.44)
below
is
is
12 micro-
of blood (12 fxmol/L). Homocysteine levels
greater than 12 pimol/L are considered high.
Twenty
to 40
percent of the general population have elevated levels of ho-
mocysteine. Individuals with high levels have almost four times the risk of suffering a heart attack compared to people
with normal list
levels. 23
Elevated homocysteine
is
high on the
of risk factors for heart disease and serves as an even
stronger marker than high cholesterol for heart disease and
blood clotting disorders. 24 25 ’
The more
relevant marker, in
my
opinion,
is
low mag-
nesium, since the major enzymes involved in homocysteine
metabolism are magnesium-dependent. 26 McCully blames too
much
protein in the diet for elevated homocysteine.
However, when magnesium, vitamin B 6 vitamin B 12 and ,
folic acid are deficient, the
body
92
is
,
not able to properly di-
Hypertension, High Cholesterol, Spastic Heart, Angina
gest protein.
The B vitamins were
typical diet a
hundred years ago;
from the
diet,
readily available in the
now
that they’re absent
homocysteine becomes elevated and heart
disease results.
When
duced through
diet or supplements, the high
levels are reversed
minish.
Ongoing
these metabolic nutrients are reintro-
and the symptoms of heart disease
research confirms that
magnesium
acid together with
cysteine in the blood
27 .
vitamins and magnesium
teine
also a
marker for
Bj 2
levels
on dietary changes
,
and
folic
of
homo-
that include
28 29 30 .
’
’
must be remembered, however, is
,
In short, the successful treatment
of homocysteinemia relies
It
B6
di-
are necessary to prevent
blood vessel damage induced by high
B
homocysteine
all
that high
homocys-
causes of mortality and signifies
that a deficiency in essential nutrients has a far-reaching effect
on the body beyond heart
disease
31 .
ATHEROSCLEROSIS It is
easy to confuse the terms arteriosclerosis and atheroscle-
rosis ; in fact,
many
people use them interchangeably. Arte-
riosclerosis is the overall
term for
sclerosis or scarring of the
arteries. Atherosclerosis is scarring
due to
fatty plaques.
rowed by be the
When
fat deposits, a
final
or thickening specifically
the diameter of an artery
blood
clot or an arterial
is
nar-
spasm can
straw that results in angina, heart attack, or
stroke. Complications of this preventable condition cause
over a third of
all
deaths in the United States.
93
The Miracle of Magnesium
SUPPLEMENT AND DRUG INTERACTIONS IN 1.
HEART DISEASE
Calcium interacts with verapamil (Calan,
Isoptin, Vere-
a calcium channel blocker, and calcium
lan). This is
interferes with the hypotensive effect of this drug. Avoid
calcium 2. Vitamin
Lasix
until
your doctor weans you off this drug.
Bi (thiamine) interacts with furosemide
(Lasix).
causes increased urinary excretion of Bi so sup-
plements of 3. Vitamin
sazide,
B6
this vitamin
may be
necessary.
interacts with hydralazine (Alazine, Apre-
Apresoline,
Unipres).
Hydralazine
causes
increased excretion of vitamin B 6 supplements of the ;
nutrient
may be
necessary.
magnesium, and potassium
4. Calcium,
interact with
furosemide, which causes urinary excretion of these minerals. Monitor levels of these nutrients and re-
place as necessary. 5.
Grapefruit (Adalat,
juice
makes
Procardia)
felodipine
more powerful;
and it
nifepidine
increases the
action of these drugs by temporarily blocking the en-
zyme
that clears
them from the
to avoid grapefruit juice while 6.
body. You
may have
on these medications.
Magnesium, calcium, potassium, and sodium
interact
with thiazide diuretics such as chlorthiazide (Diuril, Aldoril, Diachlor)
and hydrochlorthiazide
94
(Hydrodiuril).
Hypertension, High Cholesterol, Spastic Heart, Angina
Thiazides
work by increasing urinary excretion of
sodium, which presumably lowers blood pressure. However, significant
amounts
magnesium are
also excreted.
per day
may have
Magnesium
be increased to
to
on thiazide diuretics or
and
of calcium, potassium,
digitalis
at
900 mg
600 mg
if
you are
because both drugs
cause excretion of magnesium. Your doctor should do an ionized magnesium test to determine your needs. 7.
Potassium and magnesium deficiencies lead to rhythmias
in
ar-
patients on digoxin (Lanoxin).
plasma calcium increase digoxin
8. Small increases in
(Lanoxin) toxicity.
Some
specialists advise avoiding
high-calcium foods for two hours before and after taking this drug. 9.
Calcium should be supplemented due to decreased absorption of vitamin
D
with patients using cholesterol-
lowering drugs colestipol or cholestyramine.
10. Colestipol (Colestid) interferes with absorption of folate,
and vitamins
A, D, E,
and
iron,
K.
11. Cholestyramine (Quesyran, Cholybar) interferes with absorption of
and vitamins
iron, folate,
A, D, E,
and
K.
12. Heparin interferes with renal hydroxylation of vita-
min D. This could lead to osteopenia; your doctor may
need to check 1,25 (0H)2 D3 cholecalciferol
levels.
13. Vitamin K inactivates coumadin (Warfarin); coumadin interferes with vitamin
K
synthesis. 32
95
The Miracle of Magnesium
Researchers have identified various causes of damage to the inner wall of arteries, including homocysteine, an
amino
acid discussed
earlier;
called chlamydia; distorted
of
fat;
by an organism
infection
blood flow around the
mound
blood sugar; high blood pressure;
free radicals; high
and lack of oxygen. As described previously, the damaged tissue of the artery wall initiates
The inflammation then calcium, which build
attracts
up
bad cholesterol (LDL) and
into a solid scar.
homocysteine
role to play in reducing free
an inflammatory process.
Magnesium levels,
has
a
preventing
balancing blood sugar, and reducing high
radicals,
blood pressure.
HYPERTENSION Hypertension
more than is
fifty
an elevation of blood pressure suffered by million Americans.
Normal blood
120-140 over 80-90. Systolic pressure
and
relates to the
creates to is
is
number and
when
the heart
to keep the arteries open.
the
first
number
pressure that the heart muscle
push blood into the
the second
maintain
pump
is
pressure
is
is
arteries. Diastolic
pressure
the pressure that the arteries
relaxed, or
Hypertension
between heartbeats, is
either
primary or
secondary. Primary hypertension has no single cause and
occurs in 90 percent of
hypertension
is
all
hypertensive patients. Secondary
secondary to another disease. Causes of pri-
mary hypertension include high
96
cholesterol, family history,
Hypertension, High Cholesterol, Spastic Heart, Angina
smoking,
obesity, diet,
often, hypertension
exam. less
It
is
stress,
and excessive
salt intake.
diagnosed during a routine physical
presents no distinguishing signs or
the condition
dizziness,
Most
symptoms un-
very advanced, in which case headache,
is
and blurred vision can occur.
In Western medicine, the
hypertension
first line
of drug treatment for
typically the use of diuretics, or water
is
pills.
When patients are prescribed diuretics, they are warned that the most common side effect is a deficiency of potassium, which
out in the urine. To prevent
spills
to eat bananas
magnesium
is
they are advised
and oranges. What they are not told
is
that
drained out along with potassium. Recall that
magnesium deficiency relaxed and
it,
more
leads to blood vessels that are less
susceptible to
spasm and tension,
a precur-
sor to hypertension; thus the very treatment for hypertension
worsens the problem
body
is
(Ironically,
who
doesn’t help patients
cause the
33 .
replacing potassium
are also magnesium-deficient, be-
unable to deliver potassium to the
cells
without sufficient magnesium. Also, the so-called potassiumsparing diuretics
still
commonly
deplete other minerals, in-
cluding magnesium .) 34 If
blood pressure
choice
may
be
is
ACE
not controlled with diuretics, the next
inhibitors, calcium channel blockers,
antiadrenergic drugs, or vasodilators. fided to after
me
that
if
a patient’s
One
cardiologist con-
blood pressure
is
still
using five different antihypertensive drugs
time, he then
knows
the
problem
97
is
magnesium
at
high
one
deficiency.
The Miracle of Magnesium
know
Fortunately, other cardiologists
that
magnesium
is
a
physiological necessity and a pharmacological treasure to use
before pharmacological intervention. the ideal drug:
It is safe,
wide therapeutic range,
a short half-life,
diet
for hypertension. Research
magnesium
little
or no ten-
35
the
is
and
.
shows
tween the amount of magnesium 36
first
treatment of choice
a direct relationship be-
and the
in the diet
The Alturas
to avoid high blood pressure
.
strated that diets deficient in
magnesium
pertension in experimental animals
blood pressure successfully due to loss
call
cheap, and simple to use, with a
dency toward drug interactions
Even before drugs,
They
37
will
Diet
.
first
ability
demon-
produce hy-
may lower
the
combination of weight
a
and increased intake of the vitamin and mineral cofac-
tors necessary in
blood pressure control. For example,
creased levels of minerals such as potassium and in the diet
have
a suppressive effect
ions and total
magnesium
on calcium-regulating
hormones, which influence blood pressure blood pressure appears to go up
in-
38 .
as the levels of
serum magnesium go down
The
arterial
magnesium
39 .
Note Some forms of severe high blood pressure :
are
hereditary or due to kidney disease and do require medication. Also,
if
the arteries in the
body
are
damaged from long-
term atherosclerotic injury and scarring, unfortunately they
may no
longer respond to magnesium and
you may
require
medications to keep your blood pressure under control.
98
Hypertension, High Cholesterol, Spastic Heart, Angina
(
ANGINA Angina describes an episodic pain and/or
down
muscle and lites.
a
the
left
in the region of the chest
arm, due to lack of oxygen to the heart
buildup of carbon dioxide and other metabo-
Usually the pain, which can be a mild ache, pressure,
or fullness, or a crushing blow, comes on with exercise (especially in the cold), emotional stress, a
dream, and
a vivid
is
heavy meal, or even
relieved (within five minutes)
by
rest
and nitroglycerine.
The
lack of sufficient blood flow carrying life-giving
oxygen and nutrients can be due ies
to blocked coronary arter-
or spasms in these tiny vessels. Angina
ble”
when symptoms become more
rest,
is
called Prinzmetal’s,
rather than following
James B.
some
is
Another type of
angina that occurs
at
sort of physical stress.
Pierce, Ph.D., believes he has identified the cause
of Prinzmetal’s, cific
which
labeled “unsta-
severe; unstable angina
implies a greater risk for heart attack.
angina
is
which occurs most commonly
at
two spe-
times in the day, early morning and late afternoon,
when magnesium
levels are at their lowest. 40 Dr. Pierce esti-
mates that up to 50 percent of sudden heart attacks
due to magnesium deficiency.
worked
better
fact,
be
found that magnesium
than nitroglycerine for his
induced chest pains. In
would
He
may
own
stress-
Dr. Pierce could predict that he
get chest pain after a stressful day, a long drive, or an
emotional upset and would increase his intake of magne-
sium to
forestall
symptoms.
99
The Miracle of Magnesium
Risk factors for angina include magnesium deficiency,
smoking, diabetes mellitus, hyperlipidemia, type ality,
sedentary
lifestyle,
poor
diet,
A
person-
and family history of
coronary artery disease. Diagnosis of angina, to differentiate
it
from myocardial infarction and unstable angina,
EKG
cludes an
in-
(electrocardiogram) taken during an angina
attack; an exercise tolerance test,
which
is
an
EKG
taken
while on a treadmill; and a coronary angiogram (an X-ray
view of dye coronary
in the
coronary
arteries are
Once angina versal: stop
is
arteries) to assess
whether the
open or blocked.
diagnosed, the recommendations are uni-
smoking, lose weight, get blood pressure under
control (with or without drugs), and in extreme cases of arterial
blockages, undergo bypass surgery to remove blocked
arteries.
The
tion.
By
your
diet
best treatment for angina, however,
is
preven-
eliminating sugar, alcohol, and junk foods from
you help prevent
heart disease, because these
foods have no magnesium and serve only to create magne-
sium deficiency. processed-food
When you
diet,
your magnesium
you have
intake.
eat
a
more balanced, non-
a better
chance of increasing
With magnesium and other
heart-
healthy supplements, a healthy diet and exercise regimen,
you have
a fighting
page 108 for
chance of avoiding
a list of
this
supplements to cover
heart disease.
100
epidemic. See all
aspects of
Hypertension, High Cholesterol, Spastic Heart, Angina
HEART ATTACKS Myocardial infarction (MI), or heart attack, causes permanent damage to the heart muscle and requires immediate hospitalization.
MI
is
the result of coronary artery disease
due to atherosclerosis or due to spasms caused by magne-
sium deficiency. The artery may be damaged gradually by plaque, suddenly go into spasm, clot,
become blocked by
a
blood
or a combination of the above, often accelerated by ex-
cessive emotion. terial
The
calcified atherosclerotic plaque, the ar-
spasm, and even the blood clot are
worsened by magnesium
all
caused or
deficiency.
Laboratory findings distinguish
a heart attack
from an
episode of angina on the basis of heart muscle damage and certain heart
Lours days.
enzyme
levels that
become
elevated several
and remain elevated for several
after a heart attack
The immediate treatment
for an acute heart attack
usually includes anticoagulant drugs in an intravenous drip.
Intravenous magnesium given as soon as possible after heart attack, however,
may
a
provide the best protection for
the heart. Oral
magnesium treatment
clots in patients
with coronary artery disease whether the
patient
is
on
aspirin therapy or not
the considerable research rating
magnesium
41 .
also inhibits
blood
As more doctors read
on magnesium they
are incorpo-
into their intravenous and oral protocols
for heart patients.
Magnesium
has been studied for
101
its
effects
on the heart
The Miracle of Magnesium
since the 1930s
and used by injection for the treatment of
conditions
heart
1940s. 42
the
since
’
43
Magnesiums
life-
saving effects have been confirmed and reconfirmed in
many
clinics
and laboratories. For example,
in
an analysis of
seven major clinical studies, researchers concluded that
magnesium
(in
doses of 5-10 g by intravenous injection) re-
duced the odds of death by an astounding 55 percent acute MI. 44 45 ’
trials
If
Over
the past decade, several large clinical
using magnesium have
intravenous magnesium
drugs and
(2)
immediately
shown
its
beneficial effects:
given (1) before any other
is
after onset of a heart attack,
the incidence of high blood pressure, congestive heart
arrhythmia, or a subsequent heart attack
ure,
reduced. ful
One
in
is
fail-
vastly
such study, called LIMIT-2, provided power-
evidence that early magnesium administration pro-
tects the heart muscle, prevents
arrhythmia, and improves
long-term survival. 46 47 48 Magnesium might improve the ’
’
af-
termath of acute heart attack by preventing rhythm problems; improving blood flow to the heart vessels; protecting the
damaged
by
dilating
blood
heart muscle against cal-
cium overload; improving heart muscle function; breaking
down any blood
clots blocking the arteries;
and reduc-
ing free-radical damage.
Magnesium may
drug digoxin to be more
effective in the treatment of cardiac
also help the heart
arrhythmia; 49 without enough magnesium, digoxin can be-
come
toxic. 50
The suggested
criteria for
magnesium intervention were
102
Hypertension, High Cholesterol, Spastic Heart, Angina
not followed in a very large
come
did not
show
the
same
trial,
the onset of
symptoms and were
trials
LIMIT trial. 51 many hours after
results as the
blood clotting had begun.
after
LIMIT and
and oranges,
as dissimilar as apples
yet the debate over magnesium’s efficacy the
and the out-
ISIS-4,
magnesium was given
In the ISIS
The two
trial called
ISIS studies, several smaller
still
rages. Since
trials
have shown
even greater recovery from heart attacks using intravenous
magnesium, including 74 percent lower death
sium
who want
to
promote
magne-
work; supporters of magnesium
cite the
trial as
influenced
proof that
by the ISIS
it
trial
important option in your
does.
Your doctor may even be
and think magnesium care.
help
and
you
who
is
not an
who are many side
But cardiologists
looking for alternatives to drug therapy and to effects,
their
therapies, cite the ISIS trial as proof that
sulfate doesn’t
LIMIT
a
rate. 52
Pharmaceutical companies,
own drug
two hundred people with
a trial of
its
read studies thoroughly, are using
find these doctors, there
is
a
of complementary medicine associations
list
in the
it.
To
Appendix
whose doctors study
alternatives to the drug-based medicine they learned in
medical school. Because one of the major side effects of heart medications, especially diuretics, ciency,
it is
magnesium
vital that test
magnesium be
and supplemented
mg
magnesium
defi-
tested with an ionized
in heart patients
on medication. The dosage ranges from (300-1,000
is
6 to 10
who
are
mg/kg/da
per day), but this should be taken only
103
The Miracle of Magnesium
under
a
doctors supervision
if
you
on any other heart
are
magnesium dosage.
medications. See page 108 for
SPASTIC HEART Between 40 and 60 percent of people who heart attacks
may
actually have
Two
history of irregular heartbeats. 53
spasms
in the
vere heart
coronary
arteries
no
arterial
perirritable, leading to the
blockage or
and the occurrence of
a se-
as atrial fibrillation.
Both of these conditions can be caused by
Low magnesium
sudden
suspected causes are
rhythm disturbance, such
magnesium.
suffer
a deficiency of
makes the heart muscle hy-
development of
a
rhythm
distur-
bance that can’t be stopped without emergency medical intervention.
of
An
astute physician recognizes the possibility
magnesium deficiency and immediately
intravenously, as in the
LIMIT trial. Rapid
magnesium
gives
heartbeat or
atrial
tachycardia, premature beats, and atrial fibrillation have
all
responded to treatment with IV magnesium. 54 55 56 ’
The most common time around 9 a.m. on Mondays other long workweek. 57
for the onset of heart attacks
as
As mentioned
from spasm-induced angina
rience
them
same time each
ing and late afternoon, lowest.
The morning
is
people gird themselves for an-
suffer
at the
’
earlier,
attacks
is
morn-
levels are at their
likely the result of over-
night fasting and the loss of
magnesium through
Deficiency in the afternoon
may
104
who
most often expe-
day, usually in the
when magnesium
deficiency
people
the urine.
be caused by depletion of
Hypertension, High Cholesterol, Spastic Heart, Angina
magnesium induced by the
stress of the
day and not yet
replenished by the evening meal. In view of
this,
seems
it
reasonable that people with angina, heart spasms, hypertension, or heart disease
should consult with their doctors, take
an ionized magnesium take at least 200
mg
of
and,
test,
magnesium
if it
shows
a deficiency,
three times each day; be-
fore breakfast, at 2 p.m., and before going to bed.
ARRHYTHMIA Magnesiums
ability to neutralize the
heart-damaging
effects
of catecholamines (the products of stress-induced adrena-
many
of the
side effects of acute heart attack such as arrhythmia. 58
Mag-
line
and
cortisol)
is
the miracle that can prevent
nesium deficiency contributes possibly because
magnesium
is
to
abnormal heart rhythms,
responsible for maintaining
normal potassium and sodium concentrations inside heart muscle
cells.
A
balance of potassium, sodium, calcium, and
magnesium allows
for
normal heart muscle contraction and
maintains normal heartbeat.
A central pacemaker within the
heart muscle creates a normal
pumping
action that travels
across the heart; cardiac arrhythmia occurs suitable areas of the heart are forced to
the central pacemaker
by
lack of
when
assume the
when it becomes damaged
oxygen due to blocked blood
other, less
vessels,
role of
or irritated
caused by
drugs (including coffee), hormonal imbalance, or deficiency of magnesium. These tive to
new pacemakers
magnesium deficiency and
105
are even
more
are responsive to
sensi-
magne-
The Miracle of Magnesium
sium therapy that has been successfully used for over sixty years
Magnesium
59 .
also an accepted treatment for ven-
is
60 61
congestive heart failure where the
tricular
arrhythmias
heart
weak and unable
is
and before and bypass grafting
’
,
after
64 65 66 .
’
’
to
empty
after
each heartbeat
62 63 ’
,
heart surgery, including coronary
All these studies indicate that the fre-
quency of ventricular arrhythmias tration of intravenous
is
reduced by adminis-
magnesium and support an
early
high-dose administration of intravenous magnesium in the
wake
of myocardial infarction.
MITRAL VALVE PROLAPSE Magnesium
deficiency has been implicated in mitral valve
prolapse (MVP), a disorder in which the mitral valve
fails
to
completely close off one of the heart chambers during heart contraction.
It is
also called floppy valve
syndrome. Blood
rushing through the open valve can be heard as a heart mur-
mur with
a stethoscope.
more commonplace, cially in
When
cardiac ultrasound
the diagnosis of
young women. There
is
no
MVP
became
escalated, espe-
allopathic treatment
for the condition, and in mild and even moderate cases
it
doesn’t cause any symptoms. However, patients are usually
warned tal
that they should take antibiotics
work done
when having den-
to prevent the possibility of bacteria
gums being picked up
in the
from the
bloodstream and lodging on
the prolapsed valve, causing infection. This
106
is
a
very rare
Hypertension, High Cholesterol, Spastic Heart, Angina
occurrence and some doctors disapprove of antibiotics, but
who
tists
Dr.
it
remains a potential
warn
don’t
overuse of
this
liability threat to
their patients.
Melvyn Werbach, author of Nutritional
on Disease, believes that maintains that well treated
it is
a
den-
MVP
Influences
overdiagnosed and also
is
magnesium deficiency
by magnesium. The
disease that
is
valves of the heart are
pulled tight by muscles, which, like any other muscle in the
body, depend on magnesium for proper functioning. The mitral valve prolapses because Seelig reports that as
many
as 85
low magnesium
percent of
MVP
141 individuals with strongly
magnesium trol
group.
it is
levels,
compared
not held
levels
have been found in
symptomatic
MVP
had low
to only 5 percent of the con-
Magnesium supplementation given
low energy,
Mildred
patients. 67 Sixty percent of
weeks reduced the symptoms of chest anxiety,
tight.
faintness,
and
for
five
pain, palpitation,
difficulty breathing
by
about 50 percent. 68
CHELATION THERAPY Even
alternative medicine can
sium. Chelation therapy
chemical called iron
EDTA
from the body
ease. It
is
make more use
magne-
an intravenous treatment with a
that pulls out excess calcium
and
and heart
dis-
to treat atherosclerosis
would be much more convenient
as part of
of
to use
magnesium
an oral chelation protocol preventively, to keep
107
The Miracle of Magnesium
calcium from building up in the
venous
EDTA is used,
nesium are given
first place.
When
intra-
however, generous amounts of mag-
as well.
SUPPLEMENTS FOR HEART DISEASE Magnesium: 300
mg twice
per day
Coenzyme Qk> 30 mg three times
500 mg
Bromelain:
a day
three times a day between meals
Vitamin E as mixed tocopherols:
400
IU twice a
day
Crategus tincture: 20 drops two to three times a day Bioflavonoids rutin or quercetin: Biotin:
5
mg
500 mg
daily
daily.
FOR ATHEROSCLEROSIS ADD: 100 mg
Niacin (vitamin B 3 ): to
6 g
daily.
three times a day, working up
Do not use time-release
has been associated with
liver
niacin,
which
damage. Niacinamide
(which does not cause flushing)
is
not effective for
lowering cholesterol. Folic acid:
800 meg
Vitamin Be:
50 mg
daily
Vitamin B complex: Vitamin C: 1,000
Calcium: 1,000
daily
50 mg
mg three
mg
per day
times a day
daily (especially aids hypertension)
108
Hypertension, High Cholesterol, Spastic Heart, Angina
i
DIET FOR HEART DISEASE
A good diet fruit,
is
based on chicken,
whole
grains, legumes,
and vegetables. Therapeutic foods high
should be included:
and sprouts. Don’t above
fish,
all else.
disease.
garlic, fall
magnesium
onions, nuts, seeds, wheat germ,
into the trap of blaming cholesterol
Using margarine
The proper
in
is
dietary fats for
butter, olive oil, flaxseed oil,
not the answer to heart
human consumption
and coconut
oil.
The
diet for
are all
forms of heart disease should exclude alcohol, coffee, white sugar, white flour, fried foods, in margarine, baked, fried,
and trans
fatty acids (found
and processed foods).
109
CHAPTER Syndrome
6
X, Diabetes,
and Sugar Imbalance
SYNDROME The term “syndrome X”
many
believe
is
describes a set of conditions that
another fancy
just
X
name
for the conse-
quences of long-standing nutritional deficiency, especially
magnesium
deficiency.
The long
list
includes hypertension,
obesity, high cholesterol, elevated triglycerides,
uric acid. This
complex
and elevated
collectively appears to be caused
by
disturbed insulin metabolism (initiated by magnesium deficiency), called insulin resistance, diabetes, angina,
and heart
to Dr. Gerald Reaven, sible for a large
who
attack.
major factor
Syndrome X, according
coined the term,
may
be respon-
percentage of the heart and artery disease
that occurs today. Unquestionably, a
and eventually leads to
magnesium deficiency
in the origins of each of
110
its
signs
is
and symp-
Syndrome
Diabetes, and Sugar Imbalance
X,
toms, from elevated triglycerides and obesity to disturbed insulin
metabolism
1 .
’
2
INSULIN RESISTANCE Insulins job
is
open up
to
sites
on
cell
membranes
to allow
no
the influx of glucose, a cells source of fuel. Cells that
longer respond to the advances of insulin and refuse the entry of glucose are called insulin-resistant.
glucose levels rise and the
no
sulin, to
As
body produces more and more
damage
to insulin
is
in-
magnesium
that results in
deficiency, an increased risk of heart disease,
One
blood
Glucose and insulin rampage throughout
avail.
the body, causing tissue
diabetes.
a result,
and adult-onset
of the major reasons the cells don’t respond
lack of
magnesium
3 .
Some
studies
show
that
chronic insulin resistance in patients with adult-onset diabetes
sium
is is
associated with a reduction of magnesium;
necessary to allow glucose to enter
studies confirm that creas,
magnesium
when
insulin
in the cell
is
cells
released
4 .
magne-
Additional
from the pan-
normally responds and opens
the cell to allow entry of glucose, but in the case of
magne-
sium deficiency combined with insulin resistance the normal
mechanisms els
of
just don’t
magnesium
cells to insulin
work 5 .
Fortunately, the higher the lev-
in the body, the greater the sensitivity of the
and the possibility of reversing the problem
6 .
CARDIOVASCULAR METABOLIC SYNDROME (CVMS) Dr. Larry Resnick of Cornell University, involved in heart
and magnesium research for over twenty years, has another
111
The Miracle of Magnesium
V
name
syndrome X, cardiovascular metabolic syndrome
for
(CVMS), and he acterized
too
ber,
by
magnesium ies.
Americans
in general
ratio in their diet
ratio.
(Remem-
bod-
in their
men
in the world, also has a high calcium-
The U.S.
ratio in the diet.
a
study
ratio in this
(With our dietary emphasis
high calcium intake without sufficient magnesium, ac-
cording to magnesium expert Dr. Mildred Seelig,
soon have
a 6:1 ratio.)
ratio of calcium to
deficiency that it
char-
it is
have a high calcium-to-
and consequently
said to be 3.5:1, Finland’s 4:1. 8
on
says
Finland, which has the highest incidence of heart attack
to-magnesium is
when he
calcium automatically creates a magnesium
middle-aged
in
closer to the truth
high calcium-to-magnesium
a
much
deficiency). 7
is
may
we
will
Although the recommended dietary
magnesium
is
2:1, in
order to offset the
many people with syndrome
X already have,
be necessary to ingest one part calcium to one part
magnesium
in
supplement form.
MAGNESIUM DEFICIENCY AND SYNDROME According to Dr. Resnick, syndrome chronically elevated insulin levels but
nesium ions
— because
insufficient
of insulin resistance in the
opens the
cells to
X
by
if
a
caused not by
low
level of
magnesium
first place. 9
glucose only
is
As
is
of dietary
magnesium develop
human population
the cause
the cells have sufficient
show
insulin re-
that animals deprived
insulin resistance,
has the same risk. 10
112
mag-
stated, insulin
amounts of magnesium, and without magnesium, sistance occurs. Studies clearly
X
Some
and the
researchers
Syndrome
X,
Diabetes, and Sugar Imbalance
conclude that hypertension and insulin resistance
may
just
be different expressions of deficient levels of cellular magnesium. 11 The various conditions that
CVMS all have similar magnesium-deficient origins. The magnesium deficiency in syndrome X comes from
or
a
X
make up syndrome
combination of our magnesium-deficient
well-documented elevated insulin. losses, causing
loss of
magnesium
A vicious
diets
in the urine caused
cycle creates further
more syndrome
X
and the
by
magnesium
symptoms. The corner-
stone of both prevention and treatment of syndrome X,
along with
diet, is to restore
magnesium
to
normal
levels.
Unfortunately, for many, the ravages of diabetes, hypertension,
and high cholesterol have taken
then,
magnesium taken along with medications can play
beneficial role in controlling
even
their toll, but
and reducing symptoms. 12
’
a
13
DIABETES Diabetes try.
the seventh-leading cause of death in this coun-
is
There are sixteen million diabetics
in the
with the numbers increasing dramatically gets older
sugar
and
as
may
States,
population to a high-
There are two main types of diabetes. About
diet.
Type
insulin.
they
as the
more younger people succumb
10 percent of diabetics are labeled type
on
United
I
I
and are dependent
diabetes usually develops in children;
have suffered
a viral infection of the pancreas,
resulting in impaired or absent insulin production,
require insulin injections to replace their loss.
113
Type
and II
or
The Miracle of Magnesium
THREE THINGS YOU NEED TO KNOW ABOUT MAGNESIUM AND DIABETES Magnesium
1.
deficiency
may be an independent
predic-
tor of diabetes.
Diabetics both need
2.
more magnesium and
lose
more
than most people.
Magnesium
3.
is
necessary for the production, function,
and transport of
insulin.
adult-onset diabetics tend to be non-insulin-dependent,
overweight, and between In type
set.
cells
able to
do
and seventy years old
II diabetes, insulin is
body appear
of the
fifty
its
at
on-
readily available but the
to be resistant to
job of opening up the
cell
it.
Insulin
membrane
is
un-
to allow
the passage of glucose into the cell to feed the furnace.
A
third type of diabetes, gestational diabetes,
short-lived. This glucose intolerance
may
is
usually
have been present
but undetected before pregnancy but usually develops due to the stresses of pregnancy. Ionic strates the itself
testing
demon-
presence of magnesium depletion in pregnancy
and to
a greater extent in gestational diabetes.
sium depletion, or
women
magnesium
relative calcium excess,
to vascular complications of
to be addressed
14 .
The
ionic
may
Magne-
predispose
pregnancy and needs
magnesium
test is vitally
im-
portant in diagnosing magnesium deficiency in gestational
114
Syndrome
Diabetes, and Sugar Imbalance
Intervention with
diabetes.
greatly
X,
magnesium supplements can
improve the outcome for both mother and baby.
The
signs
and symptoms of diabetes
are polydipsia (ex-
and polypha-
cessive thirst), polyuria (excessive urination), gia (excessive eating). In type
I,
weight loss
sign,
but type
mon
side effect of excessive sugar,
may
be the
diabetics are usually overweight.
II
through the urine and sweat,
is
A
first
com-
which can be excreted
an overgrowth of the yeast
organism Candida albicans resulting in rashes on the skin, ,
especially in
under the breasts and
women, and
Common age,
yeast discharge in men.
complications of diabetes include nerve dam-
which mostly
affects the feet,
damage
with symptoms of numb-
and pain; atherosclerosis and heart
ness, tingling, burning, attacks;
in the groin, yeast vaginitis
to small blood vessels in the eyes
neys, causing vision loss (diabetes
is
and kid-
the leading cause of
blindness in the United States) and kidney disease; and diabetic foot ulcers,
with increased susceptibility to infection,
gangrene, and amputation. All these complications relate to
magnesium deficiency and demonstrate tive
magnesium
testing
the need for sensi-
and magnesium supplementation for
diabetes. 15
Low magnesium, widely recognized as a betes, occurs in
up
to 40 percent of diabetic patients. 16
Lack of magnesium increases the disease,
marker for
dia’
17 18 ’
risk of cardiovascular
eye symptoms, and nerve damage in diabetics,
whereas supplementation can prevent them. 19 20 21 Most im’
portantly for diabetics,
magnesium
115
is
’
a necessary cofactor
The Miracle of Magnesium
production of energy from sugar stores in the muscles
in the
and
liver.
Studies
show
moderate improvement of blood
that even
sugar control in patients with type
duce the
loss of
terol (the
good
magnesium, increases serum kind),
and decreases serum
These reductions in magnesium erides
diabetes seems to re-
I
loss
HDL
triglycerides.
and serum
and the elevation of good cholesterol
choles-
may
triglyc-
reduce the
risk of developing cardiovascular disease in patients
type
I
with
diabetes. 22
HOW
DID
WE BECOME
In non- Western cultures,
A NATION OF DIABETICS?
it
takes only one generation of
people eating a diet high in refined sugar and flour to develop diabetes. This
from
is
true of people around the world,
The immediate advice
Inuit to secluded African tribes.
given to a newly diagnosed diabetic
and other refined carbohydrates. that avoiding these unhealthy
is
to stop eating sugar
only
It is
nonfoods
common
sense
in the first place
could greatly reduce the incidence of diabetes, yet the medical
community
has been slow to promote this idea.
Partly as a result, both obesity and adult-onset diabetes are
on the
rise in children. In the last
decade, soft drink con-
sumption has almost doubled among
kids,
adding an aver-
age of 15 to 20 extra teaspoons of sugar a day just from soda
and other sugared drinks. These all-too-popular beverages account for more than a quarter of
116
all
drinks
consumed
in
Syndrome
Diabetes, and Sugar Imbalance
X,
LABORATORY FINDINGS •
DIABETES 200 mg/dl
Blood glucose greater than or equal to
(11.1
|jimol/dl)
two hours after an
glucose dissolved •
IN
blood
Incidental
High cholesterol
•
Low magnesium
the United States.
A
greater
|mmol/di) in
than
someone
equal
or
to
with signs and
of diabetes
•
2000. 23
dose of 75 g of
water
glucose
200 mg/dl (11.1 symptoms
in
oral
ions
More than
15 billion gallons
were sold
in
2001 report in the prestigious medical journal
The Lancet revealed
that each additional soft drink a
gives a child a 60 percent greater chance of
day
becoming obese. 24
Dr. France Bellisle, of Frances Institute of Health and
Medical Research, said the study provided convincing new evidence about the relationship between sugar and weight gain in children.
It is
for the first study
unfortunate that
it
has taken so long
on sugar and weight gain
—so many children and adults
and published
dicted to sugar, and there
is
to be
are already ad-
no turning back. Not
betes strikes does any medical
funded
until dia-
body recommend
cutting
back on sugar intake.
We know
from other important research
117
that obese
The Miracle of Magnesium
children develop insulin resistance, a precursor to diabetes,
more frequently than normal
fifty-three times
number
of obese children in the United States doubled be-
tween 1980 and 1994; today 24 percent of kids Recently there has been a 70 percent thirty-year-olds, and the trend
As
The
kids.
a nation,
person, so
it is
we
rise in diabetes in
shows no sign of
abating.
pounds of sugar per year per
eat 140
no wonder
are obese.
more and more people
that
are
developing symptoms of diabetes and insulin resistance and suffering
from magnesium
are studies
depressed
immune
is
adults that
demon-
response to infection that
over five hours after the ingestion of 20 tsp of sugar. 25 26 27 ’
Part of the danger with sugar ize
Even more shocking
on both animals and healthy
strate a greatly lasts
deficiency.
how much you
listed
is
that
are ingesting.
you may not even
’
real-
On ingredient labels, sugar
under carbohydrates and
is
often not distinguished
from complex carbohydrates. Furthermore, the measurements are given in teaspoons.
in grams,
even though most Americans think
People are stunned
8 to 10 tsp of sugar in
equivalent to 4.2
when
I tell
an ordinary soda
(1
them
there are
tsp of sugar
is
g).
Sugar overload can cause magnesium deficiency in several als,
ways. Processed sugar leaving
empty
is
devoid of vitamins and miner-
calories that provide
no valuable
Nutritional research reported by Dr. originator,
shows
nutrients.
Abram Hoffer
(the
with Linus Pauling, of orthomolecular medicine)
that the refining process of sugar
118
removes 93 percent
Syndrome
X,
Diabetes, and Sugar Imbalance
of chromium, 89 percent of manganese, 98 percent of cobalt,
83 percent of copper, 98 percent of zinc, and 98 percent of
magnesium
—
to tap into
its
essential to
all
own
In addition, the
life.
body has
reserves of minerals and vitamins to en-
sure sugar’s digestion. Inability to utilize sugar results in the formation of
and other abnormal
toxic products such as pyruvic acid
sugars that accumulate in the brain, nervous system, and red
blood
where they
cells,
with
interfere
cell
respiration and
hasten degenerative disease. Adding sugar to the diet pro-
duces an excessively acid condition in the body; to neutralize
it
body has
the
to
draw upon
its
stores of the alkaline
minerals calcium, magnesium, and potassium.
condition
is
severe, calcium
and magnesium
If
the acidic
will
even be
taken from the bones and teeth, which leads to decay, softening, and ultimately osteoporosis.
In summary,
magnesium plays
a pivotal role in the
secretion and function of insulin; without evitable.
it,
Measurable magnesium deficiency
diabetes and in disease, eye
many
of
its
diabetes is
is
common
in-
in
complications, including heart
damage, high blood pressure, and obesity.
When
the treatment of diabetes includes magnesium, these prob-
lems are prevented or minimized. 28
magnesium-rich water
in certain
And we do know
communities confers
tective effect against the disease. 29
’
30
that
a pro-
Magnesium supplemen-
tation improves insulin response, improves glucose tolerance,
and reduces the stickiness of red blood
119
cell
membranes.
The Miracle of Magnesium
Magnesium seems
to be essential in the treatment of periph31
With long-
many symptoms may be
irreversible,
with diabetes
eral vascular disease associated
term damage, however,
.
even with adequate magnesium and associated nutrients.
DIET FOR DIABETES
The proper
diet
the
for
prevention and treatment of
diabetes includes frequent small meals of protein (fish,
chicken,
and meat) and complex carbohydrates (whole
grains, legumes,
and vegetables) and the avoidance of simple
sugars and white flour. Stevia, from the leaves of a plant that
grows
You can
South America,
in
find
it
in health
is
food
the best sweetener to use.
stores.
Don’t use the sugar
substitute aspartame, which, in certain individuals, has been
shown
to
worsen blood sugar control and cause weight
headaches, nerve damage, and eye damage, because
made
partly
from wood
formaldehyde
32 .
alcohol,
gain, it
which breaks down
is
to
Fiber from oat bran, flaxseed, and apples
has a positive effect
on keeping blood sugar balanced.
Alternative medicine practitioners also suggest identifying any existing food allergies (dairy,
by eliminating
likely suspects
wheat, corn) from the diet for several days and then
eating several meals of one of the suspected foods in one
day and doing
a
blood sugar
elevated after eating a particular food,
is
blood
test
or finger stick for glucose.
If
it
the
may
be wise to avoid that food and find replacements that do not elevate the
blood sugar.
120
Syndrome
Diabetes, and Sugar Imbalance
X,
SUPPLEMENTS FOR DIABETES mg twice
Magnesium: 300
per day
Vitamin E as mixed tocopherols:
400
Bioflavonoids rutin or quercetin:
500 mg
Folic acid:
800 meg
Vitamin Bq:
50 mg
daily
daily
50 mg per day
mg
mg
Calcium: 1,000
twice a day
daily
Vitamin B complex: Vitamin C: 1,000
III
three times a day
daily
Chromium: chromium
picolinate,
200-400 meg
daily, al-
ternating with Brewer’s yeast: 1 tbsp three times a
day (contains glucose tolerance factor [GTF], which balances blood sugar) or specialized chromium (GTF):
200 meg
per day
Zinc picolinate:
Copper:
15 mg
2-4 mg
Selenium:
daily
daily
200 meg
daily
Manganese: 5
mg
daily
Vanadium: 15
mg
daily
Omega-3 Garlic:
fatty acids:
5 g
daily
one or two cloves
daily
121
CHAPTER
7
PMS, Dysmenorrhea,
Infertility,
Polycystic Ovarian Syndrome,
Preeclampsia, and Cerebral Palsy
THREE THINGS YOU NEED TO KNOW ABOUT MAGNESIUM AND PMS 1.
Chocolate, which
some women have
a craving for
they’re premenstrual, contains lots of
the added sugar and fat
make
it
when
magnesium, but
far less desirable
as
a food. 2.
The patent
for Prozac
has run out, so
it
has been
patented under a new name, Sarafem, for PMS. is
not a Sarafem deficiency, but
magnesium
PMS
deficiency
can cause some forms of PMS. 3.
Magnesium
is
a safe treatment for
headaches.
122
PMS
and
PMS
PMS, Dysmenorrhea,
Maureen she
didn’t
would
know what came and
get anxious
binge. She tried to keep
women
at
Polycystic Ovarian
Infertility,
it
work had begun
and tease her about her
Syndrome
over her every month, but
irritable
and go on
a chocolate
to herself, but lately the other
to
make
not-so-subtle
“evil twin.”
Then Anna
comments
sat
with her
over lunch one day and told her about a support group she
was leading for
women
of their self-help methods was to keep a journal of
toms and
to keep a
One
with premenstrual syndrome.
food diary to see
symp-
eating certain foods
if
coincided with having those symptoms.
Maureen’s journal for the next couple of months clearly
showed
that her
symptoms
and chocolate cravings,
of anxiety, fluid retention, sugar
mood
swings,
irritability, bloating,
edema, headache, and sore breasts escalated before her period and lifted the minute her period began.
Taking magnesium supplements advises
of 192
may
Melvyn Werbach, M.D. Recent
women
taking 400
95 percent experienced
mg
of
cent had fewer headaches. (Dr.
pain and had
Werbach and
women
levels
of
Red blood
magnesium
serum magnesium severe
levels,
magnesium
the premenstrual
in
less
PMS,
weight
cell
assist in
magnesium
women which
are
several other
should take 50
tamin B 6 daily with the magnesium to 1
daily for
that
nervous tension, and 43 per-
gain, 89 percent suffered less
absorption.)
showed
studies
magnesium
less breast
researchers also advise that
be the solution,
tests
mg
of vi-
magnesium
show low
with PMS. 2 Even
total
low only when there
is
a
deficiency, diminished significantly in
week
in a
group of forty women. 3 In
123
a
The Miracle of Magnesium
small
of thirty-two
trial
women,
oral
magnesium was found
to be an effective treatment of premenstrual lated to
mood
symptoms
magnesium
changes. 4 Treatment with
re-
eases
headaches, sugar cravings, low blood sugar, and dizziness related to
PMS. 5 6 ’
In another innovative research study, levels
were taken
at several
times during normal menstrual
magnesium and calcium
cycles to determine
was
tion to menstrual phases. 7 There
magnesium ion
level in the first
week
a
around the time of ovulation, and total
levels in rela-
comparatively high
after the onset of the
period, a statistically significant decrease in
sium ions and
magnesium ion
magnesium
a large decrease in
ions
magne-
serum magnesium when the serum pro-
gesterone concentration peaked in the third week. There
was
also a significant increase in the serum-calcium-to-
magnesium fourth
both the time of ovulation and the
ratio at
week
after the onset of the period.
That calcium-to-
magnesium imbalance can cause premenstrual symptoms during the is
that
week
last
of the menstrual cycle.
you can take
care of
it
easily
The good news
by taking the
amounts of calcium and magnesium. For most translates into equal
600-1,000
An
mg
right
women
this
amounts of calcium and magnesium,
of each a day in divided doses.
elegant
new study demonstrates
that estrogen and
progesterone, the female sex hormones, influence magne-
sium ion
levels in the
magnesium
relieves
body, which
symptoms
bloating, and edema. 8
of
may
PMS,
help explain
why
including migraine,
Exposure of cultured smooth muscle
124
PMS, Dysmenorrhea,
cells
Infertility,
from brain blood
Polycystic Ovarian
vessels to a
Syndrome
low concentration of
estrogen did not interfere with the level of magnesium ions.
However, exposure
to increased concentrations of es-
trogen induced significant loss of magnesium ions; at the highest concentration, the level of
magnesium
ions decreased
approximately 30 percent in comparison with controls.
Exposure of the cultured
cells to a
low concentration of
progesterone resulted in an increased level of magnesium ions.
However, when these
cells
were exposed to higher
concentrations of progesterone, cellular levels of magne-
sium ions decreased
significantly.
The higher
the estrogen
or progesterone concentration, the lower the levels of mag-
nesium
ions.
The
data in this experiment indicate that the normally
low concentrations of the female sex hormones, estrogen and progesterone, help cerebral vascular smooth muscle cells
which els
normal concentrations of magnesium
sustain
are beneficial to vascular function,
ions,
whereas high
lev-
of estrogen and progesterone significantly deplete mag-
nesium
ions, possibly resulting in cerebral vessel
reduced cerebral blood flows strual
—and thus leading to premen-
syndrome and migraine and possible stroke
These findings help to explain suffer migraines, in the
spasms and
and
why
why more women
migraines occur
second half of the menstrual cycle,
than
risk.
men
more frequently
when
estrogen and
progesterone are both elevated.
Guy Abraham, cologist,
is
a
M.D.,
a retired obstetrician
widely published author
125
who
and gyne-
has pursued
The Miracle of Magnesium
major research on premenstrual syndrome. Dr. Abraham
PMS, each
identifies four types of
hormonal
characteristics related to
1.
PMS- A
(anxiety),
nervous tension, estrogen, 2.
PMS-C petite,
which has
of
distinct
fluctuations.
with symptoms of
irritability, anxiety.
mood
swings,
Related to high
low progesterone.
(craving),
with symptoms of increased ap-
headache, fatigue, dizziness, fainting, pal-
pitations. Related to increased carbohydrate intake
and decreased prostaglandin El-type foods (from fish, nuts, seeds). 3.
PMS-D
(depression), with
symptoms
of depression,
crying, forgetfulness, confusion, insomnia. Related to
low estrogen, high progesterone, elevated male
hormone with 4.
PMS-H
excess hair growth.
(hyperhydration), with
symptoms
of fluid
retention, weight gain, swollen extremities, breast
tenderness, abdominal bloating. Related to excess
aldosterone
(a
kidney hormone that causes
fluid
retention).
Maureen had symptoms from
Her
three of the four groups.
successful treatment involved balancing
hormones and
replacing deficient nutrients. She began to take a daily table-
spoon of acids,
flax oil,
which contains omega-3
essential fatty
along with magnesium, vitamin B 6 and calcium. Es,
sential fatty acids are necessary building blocks for
126
hormone
PMS, Dysmenorrhea,
production
as
long
as
Polycystic Ovarian
Infertility,
Syndrome
they have magnesium and
B
vitamins
as cofactors.
PMS AND YOUR A fascinating diet review shows PMS followed diets
that
that
DIET
women
suffering
from
were
275 percent higher in refined sugar 79 percent higher in dairy products 78 percent higher in sodium
77 percent lower in magnesium 63 percent higher in refined carbohydrates 53 percent lower in iron
52 percent lower in zinc 9
Ounce
for ounce, chocolate has
any other food, and the late is a
sure sign of
chocolate craving
is
irresistible
magnesium
more magnesium than
urge to consume chocodeficiency. Premenstrual
widespread because magnesium
lowest around that time of a woman’s menses. is
is
at its
The answer
not to eat more chocolate, however, but to increase mag-
nesium intake by eating more nuts, whole
grains, seafood,
and green vegetables, and by taking magnesium supplements. The chocolate cravings will vanish
enough magnesium Other foods chicken,
which
to
when
there
is
in the diet.
consume
are
in
frequently
127
moderation are beef and treated
with
synthetic
The Miracle of Magnesium
PMS AND DEPRESSION Women
can get depressed before
not just depression. Yet
PMS
is
their period, but
PMS
is
often considered by medical
doctors and pharmaceutical companies to be a psychiatric condition suitable for treatment with selective serotonin
reuptake inhibitors such as fluoxetine (Prozac, Sarafem).
But remember that a lack of fluoxetine does not cause
PMS
symptoms; a lack of magnesium does. The replacement of
magnesium effects.
in
the body
fact,
In
it
will
treat
PMS
has also been found that magnesium
relieves the depression of premenstrual tively influencing
and cause no side
syndrome by
posi-
serotonin activity naturally. Sarafem has
no such claim.
hormones. Remember that one type of there
is
much
too
woman’s body. stimulation
by
estrogen and too possible to end
It is
little
PMS
when
progesterone in a
up with too much estrogen
eating, drinking, or breathing
cides, or other
occurs
hormones,
pesti-
chemical residues that mimic estrogen. The
saturated fat and arachidonic acid in meat also suppress pro-
gesterone production and cause that
worsen
fatty acids
much a
PMS
from
and can lead to painful periods. Essential
fish, nuts,
healthier fats
magnesium
symptoms of inflammation
and
seeds, including flaxseed, are
and help prevent PMS, unless you have
deficiency.
Without magnesium,
128
essential fatty
PMS, Dysmenorrhea,
Polycystic Ovarian
Infertility,
Syndrome
TREATMENT FOR PMS DIET Increase complex carbohydrates and
Reduce saturated
fiber.
fats, particularly red
meat and
dairy.
Eliminate caffeine and alcohol.
Reduce
salt intake.
Eliminate sugar.
SUPPLEMENTS Magnesium: 300-600 Vitamin B 6
:
100 mg
mg
daily
three times a day for ten days before
the period starts
Vitamin B complex:
50 mg
daily
Vitamin E as mixed tocopherols: Essential fatty acids: flaxseed
evening primrose Calcium: 1,000
mg
oil,
400
oil,
500 mg
IU daily
1 tbsp twice per day, or three times per day
daily
Progesterone: Va tsp twice a day rubbed into the skin tate inner thighs, stomach, inner arms).
progesterone cream derived from wild
excess estrogen.
450-500 mg/oz
It
should contain
Use natural
yam
to balance
USP progesterone
(have a naturopathic doctor evaluate
your hormones by testing levels Milk thistle:
(ro-
250 mg
in
your
saliva).
three times a day, to detox the
liver
129
The Miracle of Magnesium
and are not able to calm
acids are not processed properly
the irritability and inflammation of
Magnesium
ods.
common circle
is
to
deficiency
is
PMS
created
and painful peri-
by
which
stress,
is
PMS sufferers. The only solution to this vicious
to eat a healthy diet
— organic,
if
— and take
possible
nutrient supplements that include magnesium.
DYSMENORRHEA (PAINFUL PERIODS) Calcium can
act like a painkiller
create these effects
by driving magnesium out of where
into the bloodstream,
ailing tissues to treat pain.
menstrual cramps in
your period may
and relaxant, but
this
it is
So taking calcium can
showed
sium supplement (500
’
toward
alleviate
way, but taking magnesium before
studies with small groups of
doses of magnesium. 10
may
the cells and
able to be directed
forestall the pain.
periods consistently
it
11 ’ 12
mg
A
A
series of
women who relief
of
European
suffered painful
symptoms with high
balanced calcium and magne-
calcium and 300
mg
magnesium,
twice per day) helps to ensure adequate levels of both minerals and should be taken preventively. Extra magne-
sium can
also be taken
when
the pain
is
at its
worst (300
mg
once or twice a day).
Some women
find that decreasing their intake of
before their period helps prevent cramps.
obvious ter
is
that
when you
cut back
meat
What may not be
on meat you have
a bet-
chance of eating more magnesium-rich foods that will
ease
symptoms
of painful periods.
130
PMS, Dysmenorrhea,
Infertility,
Polycystic Ovarian
Syndrome
/
INFERTILITY Dr. Sherry Rogers, a diplomate in family practice, allergy-
asthma-immunology, and environmental medicine and
a
fellow of the American College of Nutrition, says that just
migraines are cerebral spasms, spasms in the fallopian
as
tubes cause tile
diet
may pregnant when
infertility.
women
get
This
explain
why
so
many
they go on a whole-foods
and take supplements including magnesium
sium
is
infer-
13 .
Magne-
required in higher amounts during pregnancy
So taking
14
.
to enhance conception also creates a healthier
it
pregnancy.
POLYCYSTIC OVARIAN SYNDROME Polycystic ovarian
syndrome (PCOS)
patients have a high
incidence of insulin resistance and glucose intolerance. In a recent consultation, a
young woman
told
me
she had been
advised to go on diabetic drugs, not because she has diabetes but because she has
PCOS
posed to lower her insulin tend to be
at risk for
ease. Since a
magnesium
and the drugs were sup-
resistance.
PCOS
patients also
hypertension, diabetes, and heart dis-
low magnesium ion
ratio are associated
level
and
a high calcium/
with insulin resistance, car-
diovascular problems, diabetes mellitus, and hypertension, a
study was done on a group of
mine the lower
effects of
levels of
magnesium
magnesium
PCOS
intervention. Significantly
ions and total
131
patients to deter-
serum magnesium
The Miracle of Magnesium
and
a significantly higher
were found
ratio
controls, a
in the
calcium-ion-to-magnesium-ion
PCOS
compared with the
patients
which gave me enough evidence
to
recommend
magnesium supplement of 300 mg twice per day
my
insulin resistance
patient’s
to treat
PCOS
and possibly her
as well. 15
SEIZURES
IN
Marie was not having
much
a
THE DELIVERY SUITE good pregnancy. She had gained too
weight, she had headaches, and her ankles and hands
were swollen with edema. She
also felt a tightness in her
head and shortness of breath. At her eight-month
visit to
the doctor, her blood pressure was elevated, she had hyperactive reflexes,
symptoms
and her urine showed protein and
sugar, the
of preeclampsia (also called pregnancy-induced
hypertension or toxemia). Preeclampsia occurs in 7 percent of
all
pregnancies and, according to the Preeclampsia Foun-
dation,
is
responsible for at least seventy-six thousand
worldwide each
ternal deaths
year.
A
ma-
rapidly progressive
condition characterized by high blood pressure, hyperactive reflexes,
edema, headaches, changes
tein in the urine,
point
it is
it
in vision,
can escalate and cause seizures,
and proat
which
called eclampsia.
Eclampsia
is
a serious condition that can cause
prema-
ture labor, premature birth, and cerebral palsy in the
new-
born. Marie’s doctor said that bed rest was the only solution to lower her blood pressure but that
132
if
she continued to
PMS, Dysmenorrhea,
Infertility,
Polycystic Ovarian
Syndrome
have high blood pressure around the time of delivery, he
would
her intravenous magnesium. Unfortunately,
give
Many researchers and clinicians recommend that pregnant women have an ionized magnesium test and take 300-600 mg of he did not have her current magnesium levels tested.
supplemental magnesium. 16
’
17 18 ’
(Always check with your
obstetrician or health care provider before adding
plement, but for both
know
magnesium has proven
that
mother and
to be safe
child.)
Although magnesium
is
the treatment of choice for
pregnancy-induced hypertension,
Magnesium
any sup-
sulfate
it
could be used more
intravenously
given
eclampsia
for
has been used successfully for more than seventy-five years. 19
the 1960s, the advent of
In
new
diuretics
anticonvulsant drugs threatened to displace
magnesium
sulfate.
Drug companies continue to run expensive
trials to
compare
their
and
clinical
newest antihypertensives and
anti-
convulsants to magnesium sulfate. Most studies show that
magnesium cations,
and
is
is,
in fact,
more
effective than synthetic medi-
decreases both infant and maternal
mortality,
extremely safe. As one researcher remarked, “The
significant
improvement
in fetal
outcome
with dietary
mag-
nesium supports the concept of magnesium supplementation during pregnancy.” 20
133
The Miracle of Magnesium
widely.
Many
researchers suggest that pregnant mothers
magnesium
routinely take
to prevent complications during
delivery and postpartum, and to help prevent premature births. 21
Clinical trials
have demonstrated that mothers
supplementing with magnesium oxide have
larger, healthier
babies and lower rates of preeclampsia, premature labor,
sudden infant death, and birth
defects, including cerebral
palsy. 22
Fortunately, Marie consulted a midwife specializing in
who was
preeclampsia, in pregnancy.
familiar with the use of
They checked
magnesium
the label of Marie’s prenatal
supplement and found that
it
nesium; she really needed
at least
contained only 150
360
mg
mg of mag-
just to
meet the
RDA (recommended daily allowance) for pregnant women. The midwife recommended supplement to give her
Marie take
that
a total of
400
mg
a
magnesium
of elemental
mag-
nesium per day and to increase her intake of magnesiumrich foods.
On
this
new
regimen, Marie noticed
many
positive
changes. She had less back and neck tension, was no longer
constipated
more
(a
common
side
effect
energy, and lost a lot of her
nally, the tightness in
sure began to go
of pregnancy), had
edema and
puffiness. Fi-
her head lessened and her blood pres-
down.
When
she told
all
this
obstetrician, he actually apologized for not being
aware of her magnesium status and said
minder for him to be more
diligent
natal supplements.
134
about
it
was
a
to her
more
good
re-
his patients’ pre-
PMS, Dysmenorrhea,
Infertility,
Syndrome
Polycystic Ovarian
/
SIDS Magnesium
deficiency has been implicated in sudden infant
common and may be
death syndrome (SIDS), which has features in
with sudden cardiac death (SCD) of adults 23
prevented by giving adequate magnesium to the mother and
An
child. 24
episode of muscular weakness induced by mag-
nesium deficiency could prevent turning
its
a distressed infant
from
head when lying facedown and thus result
in
suffocation. 25
The
triple-risk
model
for
SIDS
describes the intersec-
tion of three potential risks: (1) a vulnerable is
magnesium-deficient,
opment period
in a
(2) a critical
newborn who
adjustment and devel-
newborn displaying
hyperirritability
and unsettled cardiovascular and respiratory control, and (3)
an outside stressor such
motion or handling, these three risks
as
high-pitched noise, excessive
chill, fever,
may
trigger a shocklike episode of apnea,
unconsciousness, and slow heart it is
likely that a high
or vaccination. Together,
rate.
Researchers
feel that
proportion of SIDS deaths could be
prevented by simple oral magnesium supplementation to infants during the first critical
weeks and months of
Dr. Jean Durlach, a professor at
St.
life. 26
Vincent de Paul
Hospital in Paris and president of the International Society for the
Development of Research on Magnesium (SDRM),
states,
“This simple and cheap supplementation with doses
of 300 milligrams per day to the mother fiable.
Furthermore the beneficial
135
is
effects
ethically justi-
of
magnesium
The Miracle of Magnesium
supplementation are well established for the mother, for tal
development, and for the baby
large clinical trial of
at birth.”
He
calls for a
magnesium supplementation
nant and breast-feeding
fe-
in preg-
women. 27
CEREBRAL PALSY Cerebral palsy (CP) can occur
hemorrhage during the
when
last stages
birth weight
It
from
a fetal brain
a lack of
oxygen
can also be caused by low
and prematurity. In cerebral
damaged and
is
of pregnancy, either from
the mother’s high blood pressure or to the developing baby’s brain.
there
palsy, the brain
is
unable to properly direct muscle function.
is
The brain
gives the muscles contradictory signals,
result, the
muscles lock and become spastic or go limp, cre-
ating a disabling infants
born with
CP
also have mental handicaps. g,
of average birth weight (3,000-3,500
CP
Very low
or 3.3 lbs) are a hun-
dred times more likely to have disabling
all
g);
CP
than infants
more than 25
than half a million Americans suffer from CP, with
mated medical costs of $5
palsy
is
esti-
billion a year.
no treatment
would be “very
per-
More
occurs in very low birth weight babies.
Since there
as a
and incurable condition. Close to half the
birth weight babies (less than 1,500
cent of
and
for CP, preventing cerebral
desirable indeed,” asserts neurologist
Karin B. Nelson of the National Institutes of Health in Bethesda, Maryland. Dr. Nelson and her colleagues con-
cluded a groundbreaking study in 1995 showing that very
136
PMS, Dysmenorrhea,
low
Infertility,
Polycystic Ovarian
Syndrome
birth weight babies in four centers in California had a
lower incidence of cerebral palsy when their mothers were treated with
magnesium
intriguing finding
sulfate shortly before birth. 28 “This
means
that use of a simple medication
could significantly decrease the incidence of cerebral palsy
and prevent lifelong
and suffering for thousands
disability
of Americans,” said Zach
W.
Hall, Ph.D., director of the
National Institute of Neurological Disorders and Stroke.
The
researchers calculated that
the prevalence of cerebral palsy
magnesium
sulfate
reduced
by about 90 percent and
re-
duced the prevalence of mental retardation by about 70 percent.
They
speculate that
magnesium may play
a role in
brain development and possibly prevent cerebral hemor-
rhage in preterm infants. Dr. Diane Schendel found very similar results the fol-
lowing year while studying
a
population in Atlanta. 29 Those
mothers receiving magnesium a
sulfate delivered infants
with
90 percent lower prevalence of cerebral palsy and a 70 per-
cent lower prevalence of mental retardation.
reported that at one year of age, only
whose mothers bral palsy.
received
Only two
magnesium
sulfate
researchers
out of 113 babies
sulfate
developed cere-
of the babies had mental handicaps. In
contrast, 30 of the 405 children
magnesium
1
The
whose mothers did not
receive
had cerebral palsy and 22 had handicaps.
magnesium may prevent
The
investigators speculated that
fetal
brain hemorrhage or block the harmful effects of a di-
minished oxygen supply to the brain.
exposed to too
much oxygen
137
And
for those babies
in an attempt to
overcome
N
The Miracle of Magnesium
intrauterine deficits,
magnesium
new
cent literature review and
protects the lungs
30 .
A
re-
research suggest that magne-
sium chloride might be even more protective for the developing brain than magnesium sulfate
.
31 ’ 32
Beyond magnesium supplementation given
to expectant
mothers and to newborns, there are certain interventions that can prevent
low
some of
the subsequent brain
One
birth weight infants.
is
damage
to
specialized cranial massage
provided within hours or days of birth by licensed practi-
Naturopaths can help identify food or airborne
tioners.
lergies that
can worsen symptoms, and can
wholesome
diet
recommend
the shelf contain aspartame, a potent
You should
never expose your child to this
chemical.
SUPPLEMENTS FOR CHILDREN WITH CEREBRAL PALSY Magnesium: 10 mg/kg/day Zinc:
5
mg
per day
Vitamin B complex: Vitamin C:
200 mg
Bioflavonoids:
a
and supplement program. Be warned that
many supplements on neurotoxin.
al-
10 mg per day per day
100 mg
Essential fatty acids:
per day
DHA, 1 tsp per day; cod
1 tsp per day; flaxseed
oil,
138
1 tsp per day
liver oil,
CHAPTER
8
Osteoporosis and Kidney Stones
THREE THINGS YOU NEED TO KNOW ABOUT MAGNESIUM, OSTEOPOROSIS, AND KIDNEY STONES 1.
Magnesium
is
just as important as calcium to prevent
and treat osteoporosis. 2.
Magnesium keeps calcium will
dissolved
in
the blood so
it
not form kidney stones.
3. Taking calcium
without
magnesium
for osteoporosis
can promote kidney stones.
Muriel wondered
kidney stones
how
all at
the
she
managed
to have soft bones
and
same time. Her recent bone density
139
The Miracle of Magnesium
test
showed obvious osteoporosis, yet she was now
hospital with her third kidney stone attack.
in the
A young intern
explained that she was losing calcium from her bones, which
was being deposited
kidneys and flushed out
in her
as hard,
The
jagged crystals that were excruciatingly painful to pass.
high doses of calcium that she was taking for her osteoporosis
were only making matters worse. Muriel’s urologist did an analysis
and told her to stop eating
all
on her kidney stones
dairy products and to avoid
calcium supplements, but Muriel was very concerned that
would worsen.
her osteoporosis
When
she came to see me,
I
was
able to explain that
there are approximately eighteen nutrients essential for
healthy bones, including magnesium, the most important
mineral after calcium. Susan Brown, Ph.D., director of the
Osteoporosis Education Project in Syracuse,
New
warns that “the use of calcium supplementation of
magnesium deficiency can
in the soft tissue
such
as the joints,
promoting 1
a daily
in the face
lead to a deposition of calcium arthritis,
the kidney, contributing to kidney stones.” Dr.
ommends
York,
dose of 450
mg
of
Brown
magnesium
or in rec-
for the
prevention and treatment of osteoporosis.
els
Women with
osteoporosis have lower-than-average lev-
magnesium
in their diets, according to survey reports.
of
Magnesium
deficiency can
compromise calcium metabolism
and also hinder the body’s production of vitamin D, further
weakening bones.
140
Osteoporosis and Kidney Stones
Magnesium’s role
•
Adequate
in
bone health
is
magnesium
levels of
multifaceted.
are essential for the
absorption and metabolism of calcium. •
Magnesium
stimulates a particular
tonin, that helps to preserve
hormone,
calci-
bone structure and draws
calcium out of the blood and soft tissues back into the bones, preventing
some forms of
arthritis
and kidney
stones. •
Magnesium suppresses another bone hormone parathyroid, preventing
•
•
it
is
all
is
also required to activate an
new
necessary to form
Magnesium
With
D into its active form so
can help calcium absorption.
Magnesium that
•
from breaking down bone.
it
Magnesium converts vitamin that
called
enzyme
bone.
regulates active calcium transport.
these roles for
magnesium
to play,
it is
no won-
der that even a mild deficiency can be a risk factor for osteoporosis. Further, especially
if
there
is
too
much
calcium in the body,
from calcium supplementation,
magnesium absorption can be
as in Muriel’s case,
greatly impaired, resulting in
worsening osteoporosis and the likelihood of kidney stones, arthritis,
and heart
Other
disease.
factors that are important in the
development
of osteoporosis include diet, drugs, endocrine imbalance, allergies,
vitamin
D
deficiency,
141
and lack of
exercise.
A
The Miracle of Magnesium
detailed review of the osteoporosis literature
that
low intake of magnesium, vitamin D, boron,
chronically
and vitamins K, B 12 B 6 and ,
,
folic acid lead to osteoporosis.
Similarly, chronically high intake of protein, ride, alcohol,
The
shows
typical
and caffeine adversely Western
affect
bone health
diet (high in protein,
fined, processed foods)
sodium chlo-
salt
and
.
2’3
re-
combined with an increasing seden-
tary lifestyle contributes to the increasing incidence of
osteoporosis.
Looking
at
her
contributed to her
lifestyle,
own
Muriel saw
how much
she had
condition. She averaged five cups of
coffee, three glasses of wine,
and twenty
cigarettes a day.
This was causing calcium and magnesium, and the other nutrients that have to deal with toxins, to be
flushed out of her body. deficient fast
She drank
Her
diet
overworked or
was mostly nutrient-
food because she was constantly on the run.
a lot of soda,
causes calcium and
which
magnesium
is
high in phosphorus and
to be eliminated. She also
avoided the sun and therefore got
little
vitamin D.
Instead of becoming discouraged, Muriel was able to
look on the bright habits she
side.
At
least
now she knew what lifestyle
had to change and what supplements to
kidney stones soon became
Her
a thing of the past, her overall
health dramatically improved, and after actually an increase in her
take.
bone
142
density.
two years
there
was
Osteoporosis and Kidney Stones
/
OSTEOPOROSIS MISUNDERSTOOD AND MISTREATED Osteoporosis
neither
is
quence of aging:
Our bones were
Popular wisdom, however, is
due to
is
designed to
to treat osteoporosis.
(NIH) Osteoporosis
women
with age. Doctors
on estrogen, calcium, and drugs
bone formation
last a lifetime.
that osteoporosis in
a decrease in estrogen levels
therefore rely
of Health
normal nor inevitable conse-
a
that stimulate
The National
Institutes
Prevention, Diagnosis, and
Therapy Consensus Statement of 2000 was developed from
a
conference including eighty experts, but no mention of mag-
nesium deficiency
made
as a causative factor in osteoporosis
in the final report. 4
was
With drug companies funding most
of the osteoporosis research, there are very few large clinical trials
investigating the
duction. Although nal articles
I
magnesium connection
in
bone pro-
found over twenty- two thousand jour-
on osteoporosis,
there
were only ten
in the past
decade that studied the magnesium connection in humans.
As long
as
people are given
false
hope
that there
is
some
magic bullet in the pharmaceutical pipeline that will “cure” osteoporosis, or any other chronic disease, they will ignore the underlying reasons for their health problems.
Nonetheless,
when you
read the literature, there
is
ample evidence that many nutrients, especially magnesium, play a large role in bone development. search, for example, proves that
animal re-
magnesium depletion
bone and mineral metabolism, which
143
Much
results in
alters
bone
loss
The Miracle of Magnesium
and osteoporosis. 5 6 Magnesium deficiency
is
’
in
women with
osteoporosis compared to controls. 7
In one study, postmenopausal sis
common
very
women
with osteoporo-
were able to stop the progression of the disease with
mg
250-750
of
magnesium
any other added measures,
daily for 8
two
women
ment
for
crease in
ing
given a
A
magnesium
density. 9
fractures
women
group of
and significant
Another study showed
lactate (1,500-3,000
65 percent of the
ex-
magnesium hydroxide supple-
two years had fewer bone
women
percent of these
perienced a net increase in bone density. 8
menopausal
Without
years.
mg
daily for
were completely
by
that
two
in-
tak-
years),
free of pain
and
had no further degeneration of spinal vertebrae. 10 Magne-
sium
in conjunction
bone density trols. 11
’
12
your
in several
In fact,
magnesium
with hormonal replacement improved
if
you
groups of
women compared
are taking estrogen
and have
intake, calcium supplementation
risk of
to con-
may
a
low
increase
thrombosis (blood clotting that can lead to
a
heart attack). 13 It is
unfortunate that the treatment for osteoporosis has
been simplified into the single battle cry “Take calcium.”
Calcium dominates every discussion about osteoporosis,
is
used to fortify dozens of foods (including orange juice
and
cereal),
and
is
a top-selling
stand alone. In Chapter
1,
we
supplement, but
it
cannot
talked about the dance of
calcium and magnesium. These minerals
work
so closely to-
gether that the lack of one immediately diminishes the effectiveness of the other.
Even though the use of calcium
144
Osteoporosis and Kidney Stones
supplementation for the management of osteoporosis has increased significantly in the last decade, scientific studies
do not support such
menopause. Soft
large doses after
tissue
calcification could be a serious side effect of taking too
much
calcium. 14
Osteoporosis say
it is
is
incurable, but
if
you avoid
good range of bone-building can halt the condition even
vention
is
some
generally a progressive disease, and
if
the risk factors, take a
nutrients,
you have
and
the
exercise,
you
symptoms. Pre-
the best defense, the key elements of
which
are:
•
Eat a balanced, nutrient-rich diet
•
Take supplements of calcium, magnesium, and the various bone support factors
•
Practice a vigorous exercise
DIET FOR
program throughout
life
OSTEOPOROSIS
A high-protein diet, excess sugar, alcohol, and coffee all rob the
body
fruit
of essential minerals. Prevention in the
form of
and vegetables containing large amounts of calcium,
magnesium, and potassium contributes to maintenance of
bone mineral
density. 15
Add more
legumes, nuts, and seeds to your
some of
vegetables,
diet,
on pages 218-219.
that are high in calcium are usually
magnesium
as well, including nuts
choy (Chinese cabbage), and
abundant
in
and seeds, sardines, bok
broccoli.
145
grains,
and be sure to include
the magnesium-rich foods listed
The foods
whole
The Miracle of Magnesium
SUPPLEMENTS FOR OSTEOPOROSIS Calcium:
800 mg
per day (organic veal bone
is
the best
source, followed by calcium lactate, calcium citrate, or calcium malate)
mg twice
Magnesium: 300 Boron: 2
mg
Copper: 1-3
a day
daily (involved in vitamin
mg
D conversion)
daily (for collagen cross-linking)
mg
Manganese: 5-10
per day (stimulates the production
of mucopolysaccharides, the organic matrix of bone) Zinc:
10 mg
daily (important for
Vitamin A: 20,000 Vitamin B 6 Folic acid:
50 mg per day
:
5
mg
daily
Vitamin C: 1,000
400
III
50 mg
mg
per day
per day
daily (for
calcium absorption)
Progesterone for postmenopausal vice of your doctor to
matrix)
(forms bone matrix)
IU daily
Vitamin B complex:
Vitamin D:
bone
and
after
women under hormonal
the ad-
saliva testing
determine deficiency of progesterone: days 1-25,
use Va tsp of progesterone cream, rubbed into the skin, twice a day; take a
sure the product contains
146
break days
USP
25-31 (make
progesterone)
Osteoporosis and Kidney Stones
You can
obtain about half your mineral needs from
good organic foods. The supplement doses on the previous page assume that you are already getting minerals in your diet. If
you do not
eat a
good
diet,
your mineral supplement
amounts should be increased by 50 percent.
KIDNEY STONES Kidney stones occur when the microscopic debris excreted in the urine
becomes too concentrated
to pass freely out
of the kidneys into the bladder. Kidney stones are quite
common
in the general population.
Risk factors for kidney
stones include a history of hypertension and a intake of magnesium. 16
One
stones in the urinary tract, but
unnoticed. of
all
Up
women
percent of autopsies reveal
most
are small
to 15 percent of white will develop
low dietary
enough
men and
6 percent
one stone, with recurrence
Most kidney stones are made up of calcium phosphate, cium oxalate, or in
uric acid.
men, often with a family
Calcium stones are seen history.
of
all
whom
all
stones. Uric acid stones
cal-
chiefly
Calcium phosphate and
calcium oxalate alone are responsible for almost cent of
to pass
85
per-
make up 5-10 percent
stones. They are also seen mostly
in
men,
half of
have gout. The remaining 5 percent are rare stones
that can be formed during kidney infections.
147
in
The Miracle of Magnesium
about half of these people. Approximately one in people in the United States
is
a
thousand
hospitalized annually with ex-
cruciatingly painful stones trapped in their urinary passages.
The pain begins
abdomen
may
lower back and can radiate across the
or into the genitals or the inside of the thigh.
Diagnosis
cium
in the
is
made by
urinalysis
crystals or small stones often
and
X
ray.
A
few
cal-
need no treatment but
be relieved with painkillers and muscle relaxants. Larger
stones are treated with surgery or with lithotripsy (the
breakdown of
the stones into
little
pieces using special
ultrasound machines). Several factors can be involved in stone formation:
1.
Elevated calcium in the urine
is
caused by a diet high
in sugar, fructose, alcohol, coffee,
acidic foods pull calcium it
and meat. These
from the bone and excrete
through the kidneys. Calcium supplementation
also causes elevated calcium in the urine. 2.
Higher-than-normal urine
may
levels of oxalate
relate to a
found
in the
high dietary intake of oxalic-
acid-containing foods: rhubarb, spinach, raw parsley, chocolate, tea, and coffee.
The
oxalic acid in
promotes stone formation by binding
them
to calcium,
creating insoluble calcium oxalate. 3.
Dehydration concentrates calcium and other minerals in
the urine. Six to eight glasses of water a day
are an essential requirement for flushing the kidneys
148
Osteoporosis and Kidney Stones
properly. Increased sweating and not
enough water
intake create concentrated urine. 4.
Soft drinks containing phosphoric acid encourage
kidney stones
in
some people by
of the bones and depositing
it
pulling calcium out
in the kidneys.
Kidney stones and magnesium deficiency share the same
list
oxalates,
of causes, including a diet high in sugar, alcohol,
and
coffee.
An
important animal study shows that
(from high-fructose corn
a high dietary intake of fructose
syrup, used as a sweetener) significantly increases kidney calcification, especially
when
dietary
magnesium
U.S. Department of Agriculture warns that especially, derive
too
many
is
low. 17
The
young people,
of their daily calories from the
high-fructose corn syrup in sodas and eat few greens, which are rich in
magnesium. The phosphoric acid
also punishing to the
magnesium
One
of
magnesium
stores while wearing
in the
it
from
times of dehydration,
if
body and
away bone. 18
magnesiums many jobs
lution to prevent
is
’
is
depletes
19
to keep calcium in so-
solidifying into crystals; even at
there
is
sufficient
calcium will stay in solution. Magnesium treatment for kidney stones.
magnesium
in soft drinks
If
is
magnesium, the pivotal
you don’t have enough
to help dissolve calcium,
you
will
end up with
various forms of calcification. This translates into stones,
muscle spasms,
fibrositis,
fibromyalgia, and atherosclerosis
(calcification of the arteries).
149
The Miracle of Magnesium
Dr. George Bunce has clinically proven the relationship between kidney stones and
Bunce reported the
early as 1964, a
420
mg
magnesium
deficiency. 20
As
benefits of administering
dose of magnesium oxide per day to patients with
histories of frequent stone formation.
When
there
is
more calcium than magnesium, kidney
stones can form. Let’s look at that simple experiment from
Chapter
again to prove the point.
1
tablet in
ounce of water; note
1
how much is Then add a
still
magnesium
tablet,
If
calcium
won’t form
it
Several older studies
is
stir a
calcium
dissolves and
bottom of the
glass.
or the contents from
capsule, to the water and see
calcium dissolves. blood, then
how much
swirling around in the
crushed magnesium
a
Crush and
how much more
dissolved properly in the
crystals in the kidney.
show
the benefits of
magnesium
hydroxide in preventing stone formation. Fifty-five patients with a combined 480 stones in the previous ten years were placed on 200
mg
of
magnesium hydroxide
were followed for two to four developed
new
stone patients
developed even
who
149 patients,
group of forty-three kidney
stones over a four-year period. 21
showed
a decrease in stone
who went from
0.1 stones. Patients
a half
a
study using magnesium oxide and vitamin
natural diuretic)
and
Of
and only eight patients
did not receive magnesium, 59 percent
new kidney
earlier
year to
stones.
years,
daily. Patients
and
an average of
An
B6
(a
formation for 1.3 stones
per
were followed for between four
six years. 22 In
another study, fifty-six patients
150
PART THREE The Research Continues
While research identifying magnesium deficiency
as
a
causative factor in heart disease, migraines, and eclampsia is
clear-cut,
many
investigators
believe that
magnesium syndrome,
also plays an important role in chronic fatigue
fibromyalgia, environmental illness, and aging. vestigation needs to be that
done on these conditions
magnesium deficiency
is
a
already
know about
connection.
in-
to prove
contributing factor and that
magnesium replacement should be protocol. Let’s review
More
what many
part of the treatment
clinicians
and researchers
these conditions and the
magnesium
V
CHAPTER
9
Chronic Fatigue Syndrome
and Fibromyalgia
THREE THINGS YOU NEED TO KNOW ABOUT MAGNESIUM, CHRONIC FATIGUE SYNDROME, AND FIBROMYALGIA 1.
Magnesium fatigue
2.
deficiency
is
common
syndrome and fibromyalgia
Magnesium forms an important
in
most chronic
sufferers.
part of treatment for
chronic fatigue syndrome and fibromyalgia. 3.
Magnesium ameliorates the and chemical
fatigue,
sensitivity of chronic fatigue
fibromyalgia.
155
muscle
pain,
syndrome and
The Miracle of Magnesium
X
CHRONIC FATIGUE SYNDROME Over
the past one hundred years,
dous love
we
have had
with chemicals and electronics and
affair
marriage with scientific methodology.
tremen-
a
a strange
to say that
It is safe
important advances in chemicals, pharmaceuticals, and ence in general came out of the World space research.
The unseen
II effort
potential risks to the public
presumably outweighed by the
However, our sedentary thetic foods,
War
sci-
and
were
of the time.
crisis
lifestyle,
consumption of syn-
environmental chemicals, and polluted atmo-
sphere have coincided with a greater frequency of chronic
On
syndrome and fibromyalgia.
fatigue
magnesium and other pleted and, as
become woefully de-
nutrients have
we saw
in
Chapter
a parallel track,
4,
leave us unable to
protect our bodies and brains from chemicals.
Chronic fatigue syndrome (CFS) was formally recognized and defined as an
Control
many
(CDC)
by the Centers
illness
in 1988. Before that time,
for Disease
and even
since,
doctors considered the condition psychological.
goes by various names: Epstein-Barr, yuppie Britain,
and, in
myalgic encephalomyelitis (which identifies the
muscles and brain
as sites of
chronic fatigue syndrome
United
flu,
CFS
States,
is
which makes
inflammation). Unfortunately, the it
name
seem
that has stuck in the
related to the general-
ized fatigue that anyone can suffer at one time or another.
The name minimizes disease can have
on
a
the global impact that this devastating
persons
life.
156
Chronic Fatigue Syndrome and Fibromyalgia
The symptoms of CFS
are chronic headaches, swollen
glands, periodic fevers and chills, muscle and joint aches and pains, muscle weakness, sore throat,
gling of the extremities.
The
general feeling
credible fatigue and inability to
any
is
one of
tin-
in-
do even the simplest of
becoming exhausted,
tasks without
and numbness and
inability to
cope with
and insomnia.
stress,
There are many theories about the cause of CFS, but
one triggering factor could be
a reactivation of an already
present mononucleosis-like virus called Epstein-Barr virus.
Upward
of 90 percent of the population already has anti-
bodies to Epstein-Barr virus, meaning the virus infected
them
some point
came and went
tion
the
at
first
in their lives. In like a
most people the
normal cold or
flu.
infec-
But for some,
infection or the reactivation of the virus can be
quite severe and leave
them
feeling fatigued,
run-down, and
never truly healthy again. If
CFS
some type
is
new way, then
the people
more run-down and this infection is
of infection presenting it
affects
most severely seem
stressed than average.
It
to be
appears that
becomes chronic because the immune system
not strong enough to fight
it
off or because sufferers
come
with a chemical or pollutant that undermines
in contact
their resistance
One
itself in a
of the
and allows them to succumb to the
ways
the
immune system
is
stressed
is
generalized depletion of minerals and vitamins that
illness.
by the it
needs
to function properly.
Sheila
fit
the profile of chronic fatigue syndrome. After
157
The Miracle of Magnesium
CHRONIC FATIGUE SYNDROME DIAGNOSTIC CRITERIA MAJOR CRITERIA •
New
onset of fatigue, causing a
activity for at least six •
50 percent
reduction
in
months
Exclusion of other illnesses that can cause fatigue
MINOR CRITERIA •
Presence of eight of eleven symptoms, or
symptoms and two
six of
eleven
of the three signs
Symptoms •
Mild fever
•
Recurrent sore throat
•
Painful
•
Muscle weakness
•
Muscle pain
•
Prolonged fatigue after exercise
•
Recurrent headache
•
Migratory joint pain
•
Neurological or psychological complaints: sensitivity to
lymph nodes
bright light, forgetfulness, confusion, inability to con-
centrate, excessive •
Sleep disturbance
•
Sudden onset
of
irritability,
depression
symptom complex
158
Chronic Fatigue Syndrome and Fibromyalgia
Signs •
Low-grade fever
•
Sore throat without signs of pus
•
Palpable or tender lymph nodes
having had mononucleosis during college, she had never quite the same.
The mono seemed
weaken her immune
to
system and her adrenal glands. She worked
was constantly exposed
to germs,
felt
as a teacher
and
coming down with every
cold and flu that passed through the school. Because she traveled a lot, she received
further
weakened
ture refinishing,
her. In
and
paint. It
produces phorbol
as a causative
inoculations,
which
her spare time she enjoyed furni-
which exposed her
nishes, paint strippers, a plant that
numerous
to tung
found
in var-
made from euphorbia,
is
esters,
oil,
and has been proposed
agent for chronic fatigue syndrome
1 .
After a trip to the Far East, Sheila became more and more fatigued and a horribly
on one
came down with
a terrible
achy head, muscles, and
joints.
antibiotic after another, even
terial infection.
Her cough and
monthlong
flu
with
Her doctor put
her
though she had no bac-
chest pain finally cleared up,
but she continued to have periodic fevers, a sore throat, and sore muscles. She couldn’t exercise at
end up
in
all
bed for days, and no matter
because she would
how
she couldn’t sleep. Sheila was depressed sickness.
Sometimes she
felt as if
159
by
tired she was, this
constant
she were losing her mind:
The Miracle of Magnesium
She couldn’t concentrate, remember, or perform simple metic. She couldn’t teach and
do only the bare minimum
was so exhausted
for
that she could
to take care of herself.
Fortunately, Sheila’s doctor at a local
arith-
was involved with
a
study
university looking into possible drug treatments
CFS. She entered the blind study and did not know
which treatment she was tions
receiving.
The
medica-
three
were an anti-inflammatory drug (ibuprofen), an
anti-
depressant (amitriptyline), and magnesium glycinate. She had
weekly
visits
with
nurse to assess her symptoms, twenty-
a
four-hour urine collections, blood
tests,
and questionnaires.
After two weeks her fatigue improved, as did her muscle
weakness, twitching, poor concentration, and
At
the end of the study, Sheila
had been 300
mg
of elemental
was
if
and that she could
she wished. Sheila
told that her treatment
magnesium twice
her magnesium had been very low study,
at the
safely continue
now had
irritability.
beginning of the
with the treatment
the energy to
to take care of herself: exercise,
a day, that
do more things
shop for the right foods,
and prepare more meals from fresh foods. She knew she
was on the road
to recovery, thanks to
magnesium. Several
other studies confirm the efficacy of using magnesium for the
treatment of chronic fatigue syndrome symptoms. 2 3 4 5 ’
’
’
FIBROMYALGIA It
wasn’t until 1990 that the American College of
Rheuma-
tology established diagnostic criteria for fibromyalgia, there-
160
Chronic Fatigue Syndrome and Fibromyalgia
FIBROMYALGIA DIAGNOSTIC CRITERIA MAJOR CRITERIA •
Generalized aches or stiffness of at least three anatomat least three
ical sites for •
Six or
more
typical, reproducible
trigger points, in the •
Exclusion
months tender points, called
muscles
of other disorders that
can cause similar
symptoms
MINOR CRITERIA •
Generalized fatigue
•
Chronic headaches
•
Sleep disturbances
•
Neurological and psychological complaints
•
Joint swelling
•
Numbness
•
Irritable
•
Variation of
or tingling sensation
bowel syndrome
symptoms
in relation
to activity, stress,
and
weather changes.
by giving
it
official status as
an
illness.
Fibro- means “con-
nective tissue” and refers to the thin tissue that wraps around
muscles, and myalgia means “muscle pain.” Also called brositis,
many
of
fibromyalgia its
is
a close cousin of
symptoms: incapacitating
CFS and
fatigue,
fi-
shares
muscle and
joint pain, neuralgia, sleep disorders, anxiety, depression,
161
The Miracle of Magnesium
cognitive confusion, and digestive problems.
have mild
in addition,
throat, tients.)
(CFS
sufferers,
swollen glands, and a sore
fever,
which distinguishes them from fibromyalgia pa-
Having
a
name, however, does not define the causes
of the illness, and the American College of
Rheumatology
does not offer a curative treatment. I
believe fibromyalgia
is
the latest label for an accumula-
tion of toxins and infections lifestyle.
Twenty-six doctors
book on chronic
Our
from both environment and
who
present their cases in a
and fibromyalgia agree
fatigue
6 .
exposure to toxins, chemicals, and prescription
drugs begins
at birth.
Substances
we
think are safe can
down our immune systems and deplete our nutrient reserves. I and many other doctors believe they lead to break
CFS, fibromyalgia, and environmental list
of sufferers
7 .
illness in a
growing
Here’s a chronology of ailments and the
kinds of treatments any one of us
may
receive over the
course of a lifetime. Each treatment can trigger the next event and further drug intervention.
•
Diaper
rash, caused
by Candida
treated with cortisone creams,
ther •
growth of the
which encourage
Most
is
fur-
yeast.
Childhood ear infections can begin infections picked
•
albicans (yeast),
at birth as yeast
up from the mother during
delivery.
ear infections are treated with antibiotics.
Infections
may become
chronic and require multiple
162
Chronic Fatigue Syndrome and Fibromyalgia
courses of antibiotics, leading to diarrhea and intestinal yeast infections •
and
bowel.
irritable
Anesthetics used in surgery to place tubes in the ears
add another toxin. •
Colic can develop due to antibiotics.
•
Inability to digest milk
due to an
to frequent changes of formula •
Gas and bloating can
result
bowel leads
irritated
and further
irritation.
from hard-to-digest soy
formula. •
Eczema, aggravated by food
sensitivity,
is
suppressed
with cortisone creams. •
Allergies to foods, especially yeast, wheat, and dairy,
can arise from poor digestion. •
Asthma, which may be environmental,
is
treated with
medications including cortisone inhalers. •
Multiple colds and flus are treated with
many
courses
of antibiotics and annual flu vaccines. •
Cravings for sweets can be caused by yeast over-
growth and may cause or aggravate hyperactive behavior in children. •
Dental cavities lead to multiple mercury amalgam ings.
Toxic mercury vapor
may
be inhaled, absorbed,
or disrupt enzymes in the brain, kidneys, and •
fill-
liver.
Allergic reactions are treated with allergy shots, anti-
histamines, and cortisone sprays. •
Many
adolescents
take
for acne.
163
long-term oral antibiotics
The Miracle of Magnesium
•
Many
young
teens and
adults develop mononucleosis,
and up to 20 percent never •
feel quite as
healthy again.
Bladder infections are treated with antibiotics, which cause yeast infections.
•
Birth control tions,
which
pills
cause chronic vaginal yeast infec-
are treated with antibiotic creams.
•
Pregnancy hormones encourage vaginal yeast
•
Chronic sleep deprivation small children and
is
a
is
common
major
stress
in
all
infections.
parents of
on the immune
system. •
Irritable
bowel can develop
after a
bout of diarrhea
(attributed to traveler’s diarrhea or food poisoning)
and •
is
usually treated with antibiotics.
Hypothyroidism with body temperature below 98.2 degrees
F often occurs but remains undiagnosed and
untreated. •
Hospitalization for infections or surgery usually warrants intravenous antibiotics
•
Major colds and
flus
and
a host of other drugs.
can lead to bronchitis and pneu-
monia, which are treated with strong antibiotics. •
Chronic fatigue syndrome and
fibromyalgia
treated with anti-inflammatories, sleeping
pills,
are
and
antidepressants. •
Environmental
allergies
with extreme
sensitivities
to inhalants, especially perfumes, colognes, house-
hold products, pesticides, and molds, are treated with cortisone. •
Dysmenorrhea,
irregular periods, infertility,
164
and wors-
Chronic Fatigue Syndrome and Fibromyalgia
ening premenstrual symptoms occur due to a buildup of toxins and lack of nutrients. •
Infertility
treated with an array of synthetic hor-
is
monal drugs. •
Depression, anxiety, panic attacks, and palpitations are treated with antidepressants
•
Menopause
Magnesium and
is
and psychotherapy.
medicated with synthetic hormones.
is
depleted with every step of this scenario
body burden
results in a total
of drugs, toxins, and vari-
ous stressors. The end result looks very fatigue
look
at the
to understand
and
like
chronic
syndrome.
Let’s
up
much
how this Plants
journey through
life
why we have become so
affects the
grown on
immune
from the ground nutrient-deficient
system.
devitalized,
overworked
been poisoned by acid rain are poor
soil that
has
in nutrients, including
magnesium. Synthetic foods created by modern processing and refining are devoid of natural vitamins, minerals, and fiber.
They
are “fortified” with useless synthetic vitamins
often no minerals except calcium or iron. nutrient hardest hit
The body
is
the
not able to process junk food, with
way as
it
its
dozens
does organic food.
these chemical additives like foreign invaders and has
to detoxify are
is
by food processing.
of chemical additives, in the same It treats
Magnesium
and
them
in the liver.
The intermediary metabolites
sometimes more toxic than the
original, leaving the
hypersensitive and hyperimmune, sometimes turning
165
body
on the
The Miracle of Magnesium
body and
Magnesium
arthritis).
the
autoimmune
creating
body of these
disease (MS, rheumatoid
depleted in the attempt to detoxify
is
foreign chemicals.
There are thousands of medicinal drugs currently
Magnesium fects of
expert Mildred Seelig
many
ficiency because
body
is
may
drugs
tells
in use.
us that the side ef-
be associated with magnesium de-
magnesium becomes depleted while
the
trying to detoxify these drugs.
With the advent of could cure
all
our infectious diseases, there
these powerful drugs.
When
cannot discriminate; they
The good
and the hope that they
antibiotics
kill
is
an overuse of
antibiotics kill bacteria, they
both good and bad
bacteria.
bacteria killed in the gastrointestinal tract are then
replaced with yeast ( Candida albicans).
The
birth control
yeast in the gut, as
pill,
with
its
daily
hormone
do sugar products. Yeast overgrowth
results in episodes of alternating diarrhea
Magnesium constant
is
lost
demand
acidity of soda
due to diarrhea and
to balance the
pH
and constipation. is
of the
drained by the
body due
to the
pop and junk food.
The symptoms from are
surge, feeds
yeast and
its
breakdown products
bodywide. Often these symptoms lead one to think that
there are infections in the sinuses, throat, bladder or vagina.
A
doctor will consequently prescribe more antibiotics for
these
symptoms, which perpetuates the problem
in a vi-
cious cycle.
Acidity in the intestines from overgrowth of yeast can irritate the intestines to the
point of causing micropunctures
166
Chronic Fatigue Syndrome and Fibromyalgia
in their lining, thus allowing the
absorption of incompletely
digested food into the bloodstream. This food eign body, and the
immune system
reacts
is
now
a for-
by forming
Food
bodies to try to get rid of these foreign substances. allergies
and
sensitivities result.
body
minerals in the
that
is
Magnesium
is
anti-
one of the
responsible for neutralizing ex-
cess acidity.
Allergies are created irritate
when
inhaled chemicals and toxins
mucous membranes
the
of the nasal passages.
can trigger symptoms of asthma, which
magnesium
When
made worse by
is
deficiency.
Depression can be cals in the
They
body from
the brain
is
a direct result of
accumulating chemi-
drugs, synthetic food, and infections.
deficient in
magnesium
it
is
no longer
protected from the onslaught of chemicals such as aspar-
tame and
MSG.
Because there are no medical
tests
to confirm that
chemicals, drugs, and synthetic food are causing our
toms, people
who
normal.” This
is
feel sick are
frustrating
sufferers feel even ill
patients
thirty doctors in
often told that “everything
to
my office had
one year for
of chronically
seen between six and
their complaints. Patients
with fatigue or depression had usually been referred to psychiatrist.
Some
patients
is
and depressing, which makes
more unwell. The majority
who came
symp-
a
had been prescribed thousands
of dollars’ worth of drugs annually to treat their multiple
complaints, which usually did no good and merely added to their toxic load.
167
The Miracle of Magnesium
The complex nature of CFS and fibromyalgia
is
formida-
Even though more doctors understand and accept the
ble.
CFS, the focus of CFS research seems
existence of
on finding one
cause.
And
the treatment
Rheumatologists and psychiatrists sleeping
pills;
is
to be
symptomatic: with
treat sleeplessness
pain with anti-inflammatory drugs, painkillers,
and muscle relaxants; and anxiety and depression with anxiety drugs and antidepressants.
or nutrient deficiencies.
anti-
No attention is paid to diet
They ignore
the possibility that there
could be a nutrient imbalance, such as a magnesium deficiency, or coexisting conditions, such as a yeast infection,
thyroid, or allergies, that cause a also tend to
complex of symptoms. They
overlook possible toxicides, which allow com-
mon infections
to appear
more virulent
weakened
host. Yet
magnesium deficiency
of a
exacerbate it
the
all
symptoms
of
as
they take advantage
CFS and
is
the
Magnesium
is
also
tigue,
is
suf-
often suggested for people suffering from fa-
but rigorous aerobic exercise
who
is
exhausting to people
CFS
their
magnesium-driven energy system
or fibromyalgia,
cise also causes lactic acid buildup, it is
many
resistance against germs.
with
when
to
one of the best ways to strengthen
immune system and boost Exercise
known
fibromyalgia, and
has been effective in helping to restore health to
ferers.
low
have no energy because is
which
bankrupt. Exer-
leads to
more pain
not cleared by a particular enzyme that requires
magnesium. Even the work of metabolizing pain medications depletes
tigue patients
magnesium. This explains
why
chronic
do not do well on most medications.
168
fa-
Chronic Fatigue Syndrome and Fibromyalgia
A
buildup of
lactic acid in the
can be treated with 300
mg
muscles causes pain and
of elemental
magnesium twice
day. If the joints accumulate toxicity, arthritis can occur;
by neurotoxins, they begin
the nerves are irritated their
myelin sheath, and
disease
may
MS can
end stage of
also be the
In
result.
a
fact,
a if
to lose
autoimmune
buildup of toxicity
along with a deficiency of nutrients, such as magnesium, that are designed to clear toxins
some
from the body. According to
doctors, the definition of
ease against self”
is
autoimmune
disease as “dis-
not accurate; the disease process
by toxins and nutrient
fact, against a self altered
which greatly exaggerates
mentioned previously, magnesium
is
in
deficiencies.
Patients with fibromyalgia also have chronically levels of serotonin,
is,
low
their pain.
As
a necessary building
block for both the production and uptake of serotonin by brain
cells.
STRESS Acute episodes of
CFS and
fibromyalgia are often brought
on by exposure
to stress,
The consequent
increase in adrenaline and stress chemicals
hastens
magnesium
conditions.
loss
Low levels
of
whether emotional or physical.
and can be
magnesium
a factor in
both these
intensify the secretion
of the stress chemicals, thus increasing the risk of adverse effects of stress
and creating another vicious
169
cycle. 8
The Miracle of Magnesium
FATIGUE The overproduction to
of
adrenaline
due to
magnesium deficiency and therefore puts
leads
stress
a strain
on the
magnesium-dependent energy system of the body, causing energy depletion that leads to fatigue. Fatigue
duced with magnesium supplementation. In breakthrough occurred
sium
levels
in
CFS
were discovered
enzyme systems
in
that require
research
most
fact, a
major
when low magne-
sufferers.
Of
the
many
magnesium, the most impor-
tant ones are responsible for energy production
Magnesium and malic
often re-
is
acid,
and storage.
an acid found in apples, are
both crucial to the body’s energy production and useful the treatment of
fibromyalgia,
CFS and
fibromyalgia. In the case of
low magnesium keeps muscles
in a state of
spasm, so supplementation can aid in relieving
symptom.
A
study by
in
Guy
this painful
D. Abraham, M.D., showed
positive results in the reversal of fibromyalgia with
magne-
sium and malic acid supplementation. Fifteen patients with fibromyalgia
who took magnesium
acid (1,200-2,400
symptoms within week period
(300-600 mg) and malic
mg) experienced improvement the
first
forty-eight hours.
in their
Over an
eight-
of supplementation their degree of muscle ten-
derness and pain dropped from 19.6 points to 6.5 points,
according to standardized medical scores. 9
170
CHAPTER
10
Environmental Illness and Asthma
THREE THINGS YOU NEED TO KNOW ABOUT MAGNESIUM AND ENVIRONMENTAL ILLNESS 1.
Symptoms partially
of chemical sensitivity can be completely or
produced by magnesium deficiency.
2.
Magnesium helps
3.
Magnesium helps eliminate heavy metals from the
Dr. Sherry Rogers
is
a
detoxify toxic chemicals.
body.
diplomate in family practice, allergy-
asthma-immunology, and environmental medicine and
a
fellow of the American College of Nutrition. In private practice for
from
all
more than
thirty years, she treats very
over the world
who
ill
have environmental
171
people
toxicity.
The Miracle of Magnesium
One
of her basic
sensitivity can be
maxims
wholly or
deficiency.” She has tested to
know
this to
is
that
in part
“symptoms
produced by magnesium
enough people over the decades
be a fact and part of her success derives
from implementing magnesium therapy on
CFS and mental
all
her patients.
fibromyalgia are actually aspects of environ-
illness.
In Chapter 9
we saw how
develop over time in a toxic environment. a closer
of chemical
look
at
some environmentally
these conditions
Now we will take
sensitive people
and
the chemicals they encountered.
more often
Natalie, sometimes in jest but
would tack.”
call It
what she experienced
in anger,
a “chemical warfare at-
happened when she stepped out onto her driveway
and was enveloped by
a cloud of chemical spray
from
lawn care truck treating her neighbor’s yard. She could ther breathe nor speak. felt as
though
it
Her
lungs were
were exploding. She
on
felt
fire,
a
nei-
and her head
dizzy and shaky.
She managed to stagger into the house, where she collapsed
on the
floor.
Her husband found her
a
few minutes
took her to the hospital, where they could do very cept give her oxygen and
tell
her to
later
and
little
ex-
rest.
Natalie had been the picture of health, athletic, active,
and happy.
Now
she was chronically fatigued. She became
hypersensitive to every chemical she
came
in contact with.
She couldn’t even read; magazines and newspapers reeked of ink. Perfume samples that
came
in
magazines were a
nightmare. She had to find natural substitutes for cleaning
products and cosmetics. Plants with moldy-smelling
172
dirt
Environmental Illness and Asthma
had to go. She became
do
all
from
allergic to
was
the cooking because she their stove.
Her
many
she reacted to
diet
foods.
wool. Her husband had to sensitive to the gas
became increasingly
When
fumes
limited, as
she couldn’t even use the
telephone because holding the plastic receiver gave her hives, she tact
became
a prisoner in her
own home
with no con-
with the outside world. Elizabeth, Ted, and their children developed an array of
symptoms their
home
after
in a
As soon
renovation.
The contractor
ticed an odor.
gone
they used urea formaldehyde insulation in as
it
was
said not to worry,
few days. The only thing
that
they no-
installed, it
would be
was gone
in a
few
days was the contractor. They phoned and phoned, but he never returned their
calls.
By
the end of the
week
the
whole
family had what appeared to be a bad cold, their eyes and
noses streaming.
they
all
skin rashes, and
When the “cold” away in ten days they went to the doctor, who saw
were
didn’t go
The children developed headachy, and
irritable,
their red, irritated skin
tired.
and mucous membranes but no signs
The doctor
of infection, except for swollen neck glands.
suggested they might be allergic to something. That clinched it;
they
knew
it
was the
they could do about if
would
the chemical
the next
month
the
it.
insulation.
They
They
tried
dissipate,
but
didn’t
toughing
when
it
know what out to see
the heat
came on
problem actually got worse. They were
beginning to be allergic to more and more things, and none of
them
felt
well at
the insulation,
all.
Finally, they decided to rip out
no matter what
it
173
cost.
all
The Miracle of Magnesium
Natalie, Elizabeth, Ted, and the children eventually got better.
With much
time, effort, and
money and
the help
of sympathetic and knowledgeable health practitioners
understand the
effects of the
who
environment and the need to
detoxify and nourish the body, they regained their health.
The
modalities they used were pure water, fresh
air,
organic
foods, rotation diets, sauna therapy, vitamin and mineral sup-
plements (especially 300 day),
mg
homeopathy, acupuncture, and
Some people with
magnesium twice
of elemental
a
a positive attitude.
the above conditions are not as fortu-
nate as Natalie, Elizabeth, and Ted,
who
at least
was harming them almost from the
start.
Those who gradu-
ally build
up
ins never
know
allergies
and
sensitivities to
environmental tox-
they’re getting sick until they’ve developed
What follows
asthma, eczema, or even cancer.
of our chemical environment and health can be lessened
how
FDA
at a level
(POPs) such
which have been banned
cades but are
minuscule
still
produced
levels of
all
POPs
in the
impact on our
magnesium.
foods tested by
They included as
DDT
Exposure to
times in fetal and infant
development can disrupt or damage human hormone, productive, neurological, and
and
United States for de-
in other countries.
at crucial
an overview
is
like
causing a health concern.
persistent organic pollutants
dioxin,
its
by neuroprotectants
Toxic chemicals were found in nearly the
knew what
immune
systems.
re-
1
In 2000 the Centers for Disease Control released the
very ins
first
large-scale national survey of environmental tox-
from human samples, and the
174
results are startling.
Blood
Environmental Illness and Asthma
and urine
levels of
twenty-seven chemicals tested in
thousand Americans
CDC
mostly rely on
far
exceeded safe
Even
then, only a
few dozen of the
more than one hundred thousand chemicals are
monitored for
The EPA and
water, and soil samples to test for
air,
toxic levels of chemicals.
levels.
five
safety. 2
Perhaps
this
in
everyday use
human study will
inforce a cutback in chemical pesticide use as pledged
U.S. Department of Agriculture
(USDA) and
re-
by the
the U.S. En-
vironmental Protection Agency (EPA) in 1993. Chemical pesticide use,
pounds
however, has increased from 900 million
in 1992 to
940 million pounds in 2000, while
And
cropland has decreased. cides,
such
as
total
the riskiest chemical pesti-
organophosphates, carbamates, probable or
possible carcinogens,
still
account for over 40 percent of the
pesticides used in U.S. agriculture. 3
The average American household
generates
pounds of household hazardous waste each
year, according
to the Texas Natural Resource Conservation
“Our homes
fifteen
Commission.
contain an average of three to eight gallons of
hazardous materials in kitchens, bathrooms, garages and basements,” the government agency reports.
consequence of
all
these chemicals in our
In a California study the to
one or more
number
common
And what is
the
home environment?
of people with sensitivities
chemicals
is
“surprisingly large,”
according to researchers. Just over 6 percent of the subjects reported having a diagnosis of multiple chemical sensitivity or
environmental allergic
illness,
and nearly 16 percent reported being
or unusually sensitive to everyday chemicals. 4
175
The Miracle of Magnesium
In 1989, the
World Health Organization took
stand regarding the origins of cancer
when
it
a strong
stated that
up
to 80 percent of cancers are environmentally influenced. In
1985, the U.S. Environmental Protection a
survey of
human
fat
composition.
Agency published
found that more than
It
99 percent of the population had measurable levels of the nine chemicals they tested
including
for,
PCBs and DDT.
In
2000, 100 percent of fat samples tested were positive for chemicals. Dr. Samuel Epstein, professor of occupational
and environmental medicine Medical Center, Chicago,
at the
University of Illinois
an internationally recognized
is
authority on the toxic and carcinogenic effects of environ-
mental pollutants in
air,
water, and the workplace. His re-
DDT
search was key to banning
ingredients and contaminants in
and other problematic
consumer products
— food,
cosmetics, and household products. In his keynote address to a Health
ported that ent
Canada-sponsored cancer conference, he
we
all
compounds
now
carry
our
cells,
in
1920, and that “there
is
no
this information, activists
more than
still
hundred
none of which
safe
differ-
existed before
dose for any of them.” 5 With
have been demanding more use of
safe alternatives to chemicals.
are
five
re-
But government and industry
not listening.
Chemicals can destroy or paralyze different enzymes that protect us
from external
chemicals prevents the
body from
very chemicals. Magnesium
enzyme systems
in the
toxins. Thus, being
is
body, and
176
exposed to
protecting us from those
active in
when
its
more than 325
enzymes
are para-
Environmental Illness and Asthma
lyzed,
it is
unable to do
tion, detoxification,
its
essential
work
of energy produc-
and brain and nerve protection.
METALS AND MAGNESIUM Deborah Baker has researched
Dr.
mercury for over
a decade. 6
the health effects of
She acknowledges that mercury
pervades our environment through industrial exposure, but the major source of elemental
American population amalgams. 7 8 9 ’
’
’
is
mercury
North
mercury vapor released from dental
These amalgams
10
in the general
on
are,
average, 50 percent
mercury, and they off-gas or vaporize into your body’s
cells
every time you chew, brush your teeth, or eat anything hot or acidic. There the
number
content of
is
of amalgams in the
human
Mercury
a significant positive correlation
mouth and
the
between
mercury
tissues, including the brain. 11
magnesium
drastically increases the excretion of
and calcium from the kidneys, which
may
be caused by the
kidney damage seen in mercury poisoning. 12 Such mineral loss impairs cell production, the storage
ergy,
and
cellular repair
and
and
utilization of en-
supplementation can not only undo some of can prevent certain types of heavy metal
Long-term
fetal
magnesium
replication. Sufficient this
damage but
toxicity. 13
’
14
exposure during pregnancy to even low
concentrations of mercury can lead to irreversible develop-
mental disorders. 15 The concentration of magnesium in the placental and fetal tissues necessarily increases during preg-
nancy. 16 Unfortunately, the
demand
177
for
magnesium usually
The Miracle of Magnesium
exceeds
supply, and thus anything that further lowers
its
magnesium
levels,
such
as
mercury, puts the pregnancy and
child at risk.
Dr. Baker says that approximately 85 percent of her patients, as part of their
supplement with 300
mercury detoxification protocol,
mg to
500
mg daily of magnesium gly-
cinate, in divided doses. Patients frequently
their
comment
that
muscular pain improves while on magnesium.
Lead and cadmium have kidney and heart
a
in particular.
cumulative toxicity on the
Magnesium appears
competitive inhibitor of these two polluting metals ferent sites, particularly during
combined
to be a at dif-
intoxication. 17
A
Yugoslavian research team found that increased intake of
magnesium same with
eliminates lead via the urine and
certain other
cadmium
via the urine. 18
magnesium increased excretion Adequate magnesium
also help prevent the toxic effects of
clude
breakdown of sugar
duction of
the
heavy metals. Under experimental
conditions, they found that
of
may do
stores
levels
can
aluminum, which
in-
and disruption in the pro-
ATP energy. 19
TREATMENT The hallmark
of a mineral-deficient person
is
takes vitamins without minerals and feels
well for a while but then deteriorates. 20 eral deficiency, especially of
If
often one
worse or does
you have
magnesium, which
for energy production, certain areas of the
178
who
is
a
min-
necessary
body may be
Environmental Illness and Asthma
overstimulated by vitamin supplements, while other areas can’t respond. Therefore, illness,
it
if
you
suffer severe environmental
important to have a health care practitioner
is
monitor supplement intake and to begin with magnesium
one of your
first
supplements.
The treatment
for environmental illness
ized. Since allopathic
mental disease,
it
individual-
is
medicine does not recognize environ-
has not established treatment protocols.
According to environmental experts, magnesium
up the body’s energy and
to build
tion systems.
as
fully utilize
The source of environmental
must be eliminated or avoided; otherwise out a sinking ship by hand.
You
first
its
is
essential
detoxifica-
toxins, however, it is
like bailing
have to be aware of the
chemicals in your environment, avoid them like the plague,
and work diligently with the therapies that follow to clean out your body.
The lowly dry fillings,
up
in
cleaning chemicals, the mercury in dental
and the cleaning products under the sink
all
build
our bodies and cause chronic disease. Air purifying
machines, water
filters,
organic food, organic supplements,
and natural alternatives to chemicals provide the foundation of environmental health treatment.
DIET The key
in treating environmental illness
is
to eat organic,
free-range, unprocessed, unadulterated foods. cides
added to the
soil
The
pesti-
and the antibiotics used on poultry
179
The Miracle of Magnesium
who
and beef sicken the animals and the people
The rash
of diseases in cattle
is
eat them.
low
likely related to the
quality of their feed, the tons of drugs they are given to fat-
them up, and the
ten
gallons of chemicals sprayed
on them
to treat parasites. Unfortunately, even organic farms are
subjected to acid rain, contaminated groundwater, and polluted
air,
which means
role in detoxifying
Drink in
that
all
of us should take an active
our bodies of suspected chemicals.
six to eight glasses of
pure water
a day.
Chemicals
our environment that are water-soluble are eliminated
through the kidneys and colon, especially
enough pure water. Use
a filter that has a
if
you drink
pore size of
less
than 0.5 microns and guarantees the elimination of chemicals as well as parasites.
To
eliminate fat-soluble chemicals such as pesticides and
which can become even more
herbicides, are
broken down by the
clay wraps. Fasting
is
liver,
not recommended to eliminate toxins. cells,
which keeps
When you try to fast or diet, your down for energy, and out come the
broken
The headache, nausea,
tability are
sea
circulation.
fat stores are
chemicals.
when they
you need dry saunas and
Fat-soluble chemicals are stored in fat
them out of
toxic
light-headedness, and
irri-
not just from lack of food but from poisons
flooding your bloodstream. While fasting, Fve tasted and felt
the
numbing
before. If
you
effect of dental anesthetics
are already feeling
ill,
fasting
going to be very unpleasant experiences.
180
from decades
and dieting are
Environmental Illness and Asthma
DRY SAUNA Numerous
cultures use sweat lodges, steam baths, or saunas
for cleansing
and purification.
Many
health clubs and big
apartment buildings have saunas and steam baths, and more
and more people are building saunas
in their
own homes.
Low-to-moderate-temperature saunas are one of the most important ways to detoxify from pesticide exposure. Headto-toe perspiration through the skin, the largest organ of elimination, releases stored toxins and opens the pores. Fat that
is
down,
close to the skin releasing toxins
is
heated, mobilized, and broken
and breaking up
cellulite.
The heat
increases metabolism, burns off calories, and gives the heart
and circulation
workout. This
a
the energy to exercise. fever
is
the body’s
lating the
are
immune
employed
just that.
way
It is
is
well
a
boon
known
you don’t have
if
medicine that a
in
of burning off an infection and stimu-
system. Fever therapy and sauna therapy
at alternative
medicine healing centers to do
The controlled temperature
in a
sauna
is
excellent
for relaxing muscular aches and pains and relieving sinus
congestion. ternship
The only way
I
made
it
through
was by having regular saunas
my medical
in-
to reduce the daily
stress.
SEA CLAY WRAPS
A very
appealing method of detoxification
Contour Wrap. In Europe
it is
181
promoted
is
the Universal
as a healing
and
The Miracle of Magnesium
America
cleansing modality; however, in
only
as a
beauty treatment.
method of
tive
large tensor
A
licensed technician uses
bandages soaked in liquid clay to wrap your
sons, toxins,
to neck.
The process draws out
and edema. Measurements before and
show
the hourlong treatment
to eliminate cellulite.
is
much improved.
You can
It
The even
obtain a kit to do your
more
See the Resources section for
partial wraps.
poiafter
actual loss of inches.
health and appearance of the skin
own
can be marketed
an extremely safe and effec-
It is
detoxification.
whole body from toe
works
it
information.
SUPPLEMENTS If
you have environmental
you
illness,
are sensitive or allergic to everything.
ing supplements,
feel as
though you
When it comes
you may be unable
to tak-
to tolerate anything,
but you might be deficient in everything. This does not necessarily
mean
ment; rather, increasing
that
you
are allergic to a particular supple-
when you
take
some metabolic
body throwing
your body responds by
it,
processes,
which
off waste products that
seous or headachy. That
is
why
make you
an organic
clay wraps, and exercise should be
results in the feel
nau-
diet, saunas, sea
implemented before tak-
ing supplements.
The 100
mg
first
supplement to add
of elemental
is
magnesium.
magnesium once
182
a
Start
day and add
with
a sec-
Environmental Illness and Asthma
ond capsule fourth a
after a
week
week,
later, in
week, and
a third in the third
divided doses.
Cut back
a
you have
if
loose stools. “Green drinks” are the next food supplement to add.
They
are
sea vegetables are
made from
a variety of organic land
and flavored with
made with whey
protein
stevia.
Some “green
powder and make
cleansing drink or meal replacement for a modified
By now you should
be feeling
much
and
drinks” a
good
fast.
better and able to
add some more supplements to help boost your immune system and provide necessary building blocks for health.
Environmental
does not require high-dose sup-
illness
plementation like other diseases. In
fact, since
most mega-
vitamins and minerals are derived synthetically, better approach to use
it
is
a far
low-potency food-based supple-
ments from organic sources. Standard Process supplements, for example, meet these criteria and are available ral
health practitioners,
who
can
assist
you
in
from natu-
developing an
individualized program.
MAGNESIUM AND ASTHMA As
a child,
Gerry had eczema. Every possible skin cream
and lotion was
tried, to
no
avail,
years, the last patch disappeared
on
but its
almost immediately, however, by his
finally, after
own.
first
It
many
was followed
asthma
attack.
By
age thirty, he was suffering attacks of wheezing and coughing
when he
exercised and
when he was around
183
cats,
dogs,
The Miracle of Magnesium
v
THREE THINGS YOU NEED TO KNOW ABOUT MAGNESIUM AND ASTHMA 1.
Research shows that many patients with asthma and other bronchial diseases have low magnesium.
2.
Many drugs used loss of
in
the treatment of asthma cause a
magnesium, making symptoms only worse.
3. Patients treated with simple tion report
magnesium supplementa-
marked improvement
in
their
symptoms.
horses, dust, flowers, and chemical smells. Various medications helped initially, but after a year or
stop working.
He
two they would
wasn’t satisfied with them, anyway; one
gave him heart palpitations, and another contained cortisone,
which made him gain weight and
retain fluid.
vitamin newsletter came in the mail.
He
one day
a
threw
out, but a headline caught his attention:
it
Then
almost
“Magne-
sium Halts Asthma Spasms.”
Asthma the
is
characterized
mucous membranes
by bronchial spasm, swelling of
duction, and an inability to fully
Asthma
finds
twice as
common
3
its
empty
easiest victims in children
in
mucus pro-
of the lung, excessive
the lungs of
under ten and
boys and men, although
it
affects
percent of the general population. Tabulating
gers of an
asthma attack
is
a
air.
all
is
about
the trig-
daunting task; there seems to be
a variety of stimuli, including lung infection, exercise,
184
emo-
Environmental Illness and Asthma
tional upset,
food
sensitivities, inhalation of
cold
air
or
irri-
tating aromatic substances (smoke, gas fumes, paint fumes,
chemical fumes), and reactions to specific allergens, such as pollens.
Bronchial spasms occur in both extrinsic asthma (an
such
lergic reaction to external substances
animal
hair,
as
al-
mold, dust,
pollens and chemicals) and intrinsic asthma
(from exercise, infection, and emotional upset). The
allergic
triggers, called allergens, initiate the release of histamines in
your body, which try to eliminate the allergens by stimulating lots of
mucus
to
mop up
the allergens and push
out through sneezing, coughing, and watery eyes. the side effects of too
much
histamine
is
them
One
tightening of the
bronchial tubes, which go into spasm. Such spasms can tiate
of
ini-
episodic wheezing, coughing, and shortness of breath,
which quickly lead anxiety,
to rapid breathing, difficulty exhaling,
and dehydration. The anxiety of an asthma attack
can create a gripping fear that tenses up the whole body and is
hard to shake
Gerry
off.
really identified
with what he read about asthma
and magnesium, and he realized that tense.
He
his
whole body was
decided to try some magnesium supplements un-
der his doctor’s supervision, and with them he was able to greatly decrease his medications.
Magnesium it is
is
an excellent treatment for asthma because
a natural antihistamine
and
a bronchodilator. It has a
calming effect on the muscles of the bronchial tubes and the
whole body. Certainly, drug therapy for asthma can often
185
The Miracle of Magnesium
be lifesaving; drugs, however, are not curative.
You have
mag-
eliminate the underlying cause of asthma and replace
nesium to
fully treat this condition.
Without magnesium,
asthma can become chronic, especially
if
the various trig-
gers are not eliminated; even the fear of an attack can
nify the emotional
to
mag-
component. Conventional allergy shots
have been used for decades to try to trick the body into accepting irritating allergens but often do not work, especially
when
the condition
is
According to Dr. consists of
Seelig, the
The
in loss of is
drug treatment of asthma
21 .
as beta blockers, corti-
side effects of these drugs include
magnesium deficiency
and sudden death
which
a nutrient deficiency.
magnesium-wasters such
sone, and ventolin. severe
due to
that can result in arrhythmia
Theophylline (Aminophylline) results
magnesium and suppression of vitamin B 6
activity,
necessary for magnesium function. Prednisone
wastes magnesium, causes sodium retention and fluid retention, suppresses
vitamin D, and causes increased urinary ex-
cretion of zinc, vitamin K, and vitamin
Childhood asthma can be
methods of pean study,
.
life-threatening;
but safe
treating this condition can be added. In a a
group of children
spite of conventional
sulfate
C 22
intravenously.
who had
Euro-
deteriorated in
drug therapy were given magnesium
Comparing
the
magnesium group
with the placebo group, the magnesium group had lower clinical
of
asthma scores and
improvement
riod.
a significantly greater percentage
in lung function over a ninety-minute pe-
No significant side effects were observed 23 .
186
Environmental Illness and Asthma
Dr.
Lydia Ciarallo in the Department of Pediatrics,
Brown
University School of Medicine, treated thirty-one
asthma patients ages ing
six to eighteen
who were
deteriorat-
on conventional treatments. One group was given magne-
sium
sulfate
and another group was given
intravenously.
At
fifty
both
minutes the magnesium group had a
improvement
significantly greater percentage of tion,
saline solution,
in lung func-
and more magnesium patients were discharged from the
emergency department than the placebo group
who went on
to hospitalization. 24
Another study showed lar
magnesium
levels
found that patients
between
a correlation
intracellu-
and airway spasm. The investigators
who
had low
cellular
magnesium
levels
had increased bronchial spasm. This finding confirmed not only that magnesium was useful in the treatment of asthma
by
dilating the bronchial tubes but that lack of
was probably
A as
magnesium
a cause of this condition. 25
team of researchers
surprisingly
common,
identified
finding
it
magnesium deficiency in
65 percent of an
intensive-care population of asthmatics and in
1
1
percent of
an outpatient asthma population. They supported the use of
magnesium
to help prevent
asthma
several antiasthmatic actions. laxes airways
As
a
attacks.
Magnesium
calcium antagonist,
and smooth muscles and
it
has re-
dilates the lungs. It
also reduces airway inflammation, inhibits chemicals that
cause spasm, and increases anti-inflammatory substances
such
as nitric oxide. 26
The same study established
that a
187
lower dietary magnesium
The Miracle of Magnesium
was
intake
with
associated
impaired
lung
function,
bronchial hyperreactivity, and an increased risk of wheez-
The study included 2,633 randomly
ing.
ages eighteen to seventy. Dietary calculated
by
a
selected adults
magnesium intake was
food frequency questionnaire, and lung
function and allergic tendency were evaluated.
The
investi-
low magnesium intake may be
gators concluded that
in-
volved in the development of both asthma and chronic obstructive airway disease.
DIET Avoid
sugar. Limit red
meat and
dairy,
which contain sub-
stances that increase inflammation in the body. Increase yel-
low vegetables and green
leafy vegetables,
which contain
substances that inhibit inflammation. Increase intake of fish oils,
seed and nut
salmon), flaxseed
oils,
oil,
cold-water fish (herring, sardines,
and walnuts to reduce inflammation.
Eat grapes; grape skins contain quercetin, which prevents histamine release and inhibits inflammatory products.
Try der, a
a liquid fast:
Use
a therapeutic
whey
protein
pow-
green drink, and/or fresh, organic juices plus fiber
for three days, followed
Get out of the
by
a vegetarian diet for
rut of eating the
and eliminate possible food
four days.
same foods every day
allergies.
Eggs, shellfish, and
peanuts usually cause immediate sensitivity reactions; milk, chocolate, wheat, citrus, and food colorings cause delayed
food reactions. Carefully check
188
labels in the grocery store
Environmental Illness and Asthma
and speak up
in restaurants to avoid
even small amounts of
potential allergic triggers.
Avoid (e.g.,
and
aspirin
nonsteroidal
ibuprofen), which can cause allergic reactions.
Clean out environmental cats
anti-inflammatories
allergies:
Find other homes for
and dogs. Avoid wall-to-wall carpeting, wall hangings,
and feather pillows. Frequently replace or clean for heating and cooling systems.
sound cleaning products. Use allergies.
Research
a
air filters
Obtain environmentally
vacuum
cleaner specific for
HEPA air cleaners and ozone generators.
SUPPLEMENTS -
Magnesium: 300 Vitamin B 6
:
mg
50 mg
Pantothenic acid:
twice a day
twice a day
500 mg
daily
Vitamin C: 1-2 g daily
Vitamin E as mixed tocopherols: Quercetin:
500 mg
Selenium:
250 meg
Flaxseed
oil:
400
III
daily
three times a day a day
1-2 tbsp
daily
Hydrochloric acid: 5 grains, 1 tablet per day at the end of a meal, increasing to
one with each meal.
189
CHAPTER 11 Health and Longevity
THREE THINGS YOU NEED TO KNOW ABOUT MAGNESIUM AND AGING 1.
Magnesium
is
deficient
in
who have
Alzheimer’s
magnesium
deficiency;
people
disease or Parkinson’s disease. 2.
Aging as
we
itself is
a risk factor for
get older
we become more
sium and therefore require more
in
deficient in
our diet and
magnein
sup-
plement form. 3.
Magnesium binds and eliminates
toxic
chemicals and
metals to keep them from contributing to symptoms of aging.
190
Health and Longevity
Three hundred years ago, people didn’t
do today. They
live as
long as
we
lived in such unsanitary conditions that
simple scrapes and cuts became mortal wounds. Bathing
was looked upon with suspicion. Tuberculosis, fostered by sun exposure, lack of fresh
extremely close quarters,
little
vegetables, and dampness,
was highly contagious and struck
down many
made
ventilation if
in their prime.
Indoor
fires
without adequate
for chronic bronchitis and
the people even lived long
enough
emphysema,
to develop these
conditions.
When we
implemented universal
sanitation, the infec-
tious diseases
began to recede. The land was
plants soaked
up
vital nutrients.
humans absorbed them from duce. in a
The
Farm animals
eating fresh
factories belching
ate
and
them, and
meat and fresh pro-
industrial revolution, however,
new way, with
still fertile,
harmed our health
smoke and chemical
poisons. Industrial farming techniques began poisoning the soil
with pesticides, herbicides, and nitrogen
soil
became
are better off in this century with
drugs and medical technology, but
become
toxic
as
Popping antiaging
and undermine our health, especially
your
life.
An
ents, exercise,
pills
our
we’ve seen, these can
polluted environment where our basic nutrition
to
The
lifeless.
We may think we also
fertilizers.
is
in a
impaired.
and megavitamins do not add years
excellent diet that provides optimal nutri-
and an outgoing, optimistic attitude are the
true keys to longevity.
Aging
in industrialized societies
191
is
associated with an
The Miracle of Magnesium
increasing prevalence of hypertension, heart disease, re-
duced insulin general
is
sensitivity,
and adult-onset diabetes. Aging
associated with altered calcium and
in
magnesium
ion levels, indistinguishable from those observed in hypertension and diabetes. insulin resistance
and
sion, heart disease, states, as
well as
tion of
its
we
talked about
role in exacerbating hyperten-
and diabetes mellitus. Insulin-resistant
what
are characterized
In Chapters 5 and 6
1
is
often thought of as “normal” aging,
by the accumulation of calcium and deple-
magnesium
in the cells.
cal researchers suggest that
it is
With
all this
in
mind,
clini-
the disturbance of calcium
and magnesium ions that might be the missing link responsible for the frequent clinical coexistence of hypertension,
atherosclerosis,
As
and metabolic disorders
in aging. 2
evident from animal experiments and epidemiologi-
cal studies, tibility to
magnesium deficiency may
increase our suscep-
cardiovascular heart diseases as well as accelerate
“Smart drugs” such as piracetam, oxiracetam, pramiracetam, and aniracetam are thought to enhance learning, facilitate
the flow of information between the two hemi-
spheres of the brain, help the brain chemical
injuries,
Magnesium
much
and supposed to be free of side
fits all
less costly
resist physical
the
criteria for
and has no side
192
effects.
“smart drugs,” but effects.
and
it
is
Health and Longevity
3
In a study
aging
.
sium
levels
were
on nursing home
low magne-
residents,
significantly associated with
two conditions
cramps and diabetes mellitus
that plague the elderly, calf
4 .
Centenarians (individuals reaching a hundred years of age)
have higher
total
body magnesium and lower calcium
than the usual elderly person
levels
5 .
FREE RADICALS, ANTIOXIDANTS, AND AGING
A
free radical
is
an unstable molecule that
normal body metabolism. within our
own
body’s
It
is
cells react
is
the product of
formed when molecules with oxygen.
It
has an un-
paired electron that tries to steal a stabilizing electron from
another molecule and as a consequence can produce harmful effects. External sources of free radicals include cals (pesticides, industrial pollution,
chemi-
auto exhaust, cigarette
smoke), heavy metals (dental amalgam, lead, cadmium),
most infections
(viruses, bacteria, parasites),
and even excessive
hol, allergens, stress,
X
rays, alco-
exercise.
Antioxidants are vitamins and minerals such as magnesium, selenium, vitamin C, and vitamin radicals.
The
greater the
is
free to
that turn off free
amount of other antioxidants
body, the more magnesium oxidant and
E
is
spared from acting as an anti-
perform
its
antioxidants protect the level of
many
other functions. So
magnesium
in the body,
which prevents elevation of calcium, which can cular muscle
spasm
6 .
If
in the
there are not
193
lead to vas-
enough antioxidants
The Miracle of Magnesium
available,
overabundant
free radicals begin to
destroy normal, healthy
damage and
Free radicals are necessary
cells.
and normal products of metabolism, but uncontrolled
free
production plays a major role in the development of
radical
degenerative disease, since free radicals can damage any
body
structure: proteins,
radicals are implicated in
enzymes,
fats,
more than
even
DNA.
sixty different health
autoimmune
conditions, including heart disease,
Free
disease,
and cancer.
According to current research, low magnesium
levels
not only magnify free-radical damage but can hasten the
production of free radicals skin cells found that of free radicals
8
cells
One
study utilizing cultures of
low magnesium doubled the
In addition, cells
.
sium were twice
were
7 .
grown
grown without magne-
as susceptible to free radical
in
damage
cells
low-magnesium
in
were deficient
from hamsters fed
magnesium and con-
sequently more susceptible to free-radical damage. pears that low the cell
It
ap-
magnesium damages
the vital fatty layer in
more
susceptible to destruc-
membrane, making
it
tion and allowing leakage through the
A
as
normal amounts of magnesium. An-
other study showed that red blood diets
levels
number
membrane.
of reports have identified pesticides as a
cause of Parkinson’s disease (which affects over one million
Americans), with in-home exposure to insecticides carrying the highest risk
oxidant
which
made
9 .
in
Glutathione
all
is
a naturally occurring anti-
the cells of the body, including neurons,
acts to detoxify the
body
194
of certain chemicals. Cells
Health and Longevity
grown
in
magnesium-deficient conditions, however, have
lower glutathione
magnesium
free radicals to a
much more
cells
fall
fall
susceptible to free
damage. Neurosurgeon Dr. Russel Blaylock
radical
low-
culture causes glutathione levels to
making the
rapidly,
that a
cell
Adding
levels.
tells
us
in cellular glutathione within part of the brain
called the substantia nigra appears to be
one of the
earliest
findings in Parkinson’s disease. 10
ALZHEIMER’S In
North America, approximately
lation over sixty-five, fer
from Alzheimer’s.
loss,
out
10 percent of the popu-
and 50 percent over eighty-five, It is
associated with severe
suf-
memory
impaired cognitive function, and inability to carry
activities of daily life.
nosed when ruled out ciency,
all
(e.g.,
Alzheimer’s disease
is
often diag-
the other identifiable brain conditions are brain tumor, alcoholism, vitamin
B !2
defi-
mercury amalgam poisoning, depression, hypothy-
roidism, Parkinson’s, stroke, excessive prescription drug use).
In truth,
it is
only
at
autopsy that a definitive diagnosis can
be made. The brain will show the identifying characteristics of Alzheimer’s: plaques and tangles in the nerve fibers, particularly in the cerebrocortex
Abram
and hippocampal
area. Dr.
Hoffer, the founder of orthomolecular medicine
along with Linus Pauling, cautions that almost half the di-
agnosed cases of Alzheimer’s
may
be such treatable condi-
tions as simple dehydration, prescription drug intoxication,
195
The Miracle of Magnesium
severe cerebral allergies to foods or chemicals, or chronic nutrient deficiencies.
Chemicals and toxic metals are associated with Alzheimer’s disease, especially
aluminum, which many Americans are ex-
posed to through aluminum pots, aluminum cans, aluminumcontaining antacids and antiperspirants, tap water that
may be high in aluminum
.
aluminum 11 ’ 12
and
foil,
Considerable re-
search has proven that brain neurons affected in Alzheimer’s disease have significantly higher levels of
normal neurons. Alzheimer’s patients
low magnesium
levels
aluminum than
also have consistently
within the hippocampus, the area of
the brain
most damaged by Alzheimer’s. Aluminum
to replace
magnesium
mimicking
its
also replace
in certain
function but causing harm.
magnesium
in the brain,
channels in the brain nerve
cium
enzyme systems
cells
which
is
able
in the body,
Aluminum
leaves calcium
wide open, allowing
to flood in, causing cell death
can
cal-
13 .
PARKINSON’S DISEASE Similarly,
with Parkinson’s disease aluminum can be a con-
tributing factor in central nervous system degeneration. In
one autopsy study, calcium and aluminum were elevated
in
compared
to
the brains of victims of Parkinson’s disease as
people with normal brains
Enzymes function cess to the
14 .
in the
body only when they have
ac-
proper cofactors, which are mostly vitamins and
minerals, especially magnesium, selenium, vitamin C, vita-
196
Health and Longevity
age, so at particular risk are elderly
an adequate diet and
who
people
citizens take
age six to eight medications regularly.)
which many
up symptoms caused by
not eat
use drugs that deplete the body’s
magnesium. (Studies show that senior
fects of antacids,
who do
a
bad
Add
on
aver-
to that the ef-
elderly people take to cover diet.
Antacids suppress nor-
mal stomach acid and can lead to incompletely digested food, which causes gas, bloating, and constipation. Another
hidden danger
is
the use of
aluminum
But aside from the direct toxic
may
mentia
also be caused
Several studies result
when
show
in
most
effect of
antacids.
aluminum, de-
by magnesium depletion
that severe neurological
alone. 17
syndromes can
conditions cause extremely low levels of brain
magnesium, such
as
with the chronic use of diuretics, which
millions of people take to control high blood pressure. These
neurological conditions can present as seizures, delirium,
coma, or psychosis, which are quickly reversed by administering large doses of intravenous magnesium. Excessive amounts
of aspartame and
may
people
direct effect,
MSG
also cause
which
is
(glutamate) in the diet of elderly
symptoms
of dementia due to their
also magnified in
Dr. Jean Durlach, a preeminent
magnesium
deficiency.
magnesium expert
France, sums up the current research
in
on magnesium and
aging. 18
1.
Chronic marginal magnesium deficiency reduces span in
2.
life
rats.
Magnesium
deficiency accelerates aging through
199
its
The Miracle of Magnesium
various effects
on the neuromuscular,
cardiovascular,
and endocrine apparatus; kidneys and bones; and im-
mune, 3.
antistress,
and antioxidant systems.
In developed countries, ginal age:
magnesium
intake
is
mar-
throughout the entire population regardless of
around 4 mg/kg/day instead of the 6 mg/kg/day
recommended
to maintain satisfactory balance.
ever, the elderly
population
How-
extremely heteroge-
is
neous: diseases, handicaps, and physical or psycho-
impairments
logical
expose
individuals
to
more
severe nutritional deficiencies. 4.
Around
the age of seventy,
becomes two-thirds of what 5.
magnesium absorption it is
at
age thirty.
Various mechanisms of deficiency include intestinal malabsorption; reduced bone uptake and mobilization (osteoporosis); increased urinary losses; chronic stress;
severe
insulin resistance leading to diabetes with
magnesium
loss in the urine; lack of response
to adrenal stimulation; loss caused
by medication,
especially diuretics; alcohol addiction;
and cigarette
smoking. 6.
Magnesium
deficiency
symptoms
clude central nervous system
in the elderly in-
symptoms
that
seem
largely “neurotic”: anxiety, excessive emotionality, fatigue, headaches, insomnia, light-headedness, dizzi-
ness,
nervous
fits,
sensation of a
lump
in the throat,
and impaired breathing. Peripheral nervous system signs are
common:
pins and needles of the extremi-
Health and Longevity
ALTERNATIVE THERAPIES FOR ALZHEIMER’S Avoid mercury
fillings
must be done by
or have them replaced. But the
a dentist
proper removal can result into the tissues. Clean out
who in all
work
specializes in this area; im-
more mercury being
released
the chemicals in your
home
and immediate environment. Eat organic food. Exercise and take regular saunas.
203
V
PART FOUR Testing and Supplements
CHAPTER
12
Magnesium Requirements,
Testing,
and Sources
MAGNESIUM REQUIREMENTS The Recommended Daily Allowance (RDA) at
the
the
minimum level to
stave off deficiency
for nutrients
is
set
symptoms, not
at
maximum that ensures good health. But even with the RDA
set so low,
most Americans
The following
table
are
still
deficient in
magnesium.
shows the Recommended Daily Al-
lowances (RDAs) for magnesium in children and adults. Children 1 to 3 years: Children
4
to
8
Children
9
to
13
years:
80 mg
130 mg
years:
240 mg
Men
Women
Pregnancy
Lactation
Age 14-18
410 mg
360 mg
400 mg
360 mg
Age 19-30
400 mg
310 mg
350 mg
310 mg
Age 31 +
420 mg
320 mg
360 mg
320 mg
Life
Stage
207
The Miracle of Magnesium
The and
is
RDA
for
roughly 6
magnesium
mg
mg/kg
also expressed in
is
per kg (2.2 lbs) of
body weight. This
standard helps to determine the magnesium requirements for
someone who
who
overweight, because a fifty-year-old
is
weighs 300 pounds needs more magnesium than
fifty-year-old
who
is
100 pounds.
Many magnesium increased.
RDA
experts feel that the
Twenty years of research shows
conditions approximately 300
merely to offset the daily
moderate
stress
mg
of
losses. If
that
you
are
ideal
required
is
under mild to
caused by a physical or psychological dis-
emotional up-
your requirements for magnesium
Mildred Seelig
should be
under
magnesium
ease, physical injury, athletic exertion, or
heaval,
a
feels
that adolescent
escalate.
boys and
1
girls
’
2
Dr.
who
may need 7-10 mg/kg/day and pregnancy requirements should be a minimum of 450 mg a day or up to 15 mg/kg/day. 3 An average diet may supply about 120 mg are athletic
of
magnesium per
1,000 calories, for an estimated daily in-
take of about 250 mg. 4
’
5
Since at best the
absorbing only half of what
is
taken
in,
body
is
actually
researchers feel that
most people would benefit from magnesium supplementation.
Otherwise, body tissue must be broken
supply
vital areas
of the
body with
essential
down
to
magnesium. 6 7 ’
MAGNESIUM TESTING You’ve heard the saying “To
err
is
vine”? In the medical world, to err
208
human,
is
human,
to forgive to test
is
is
di-
divine.
Magnesium Requirements,
Laboratory
tests
Testing,
should be used to confirm what our senses
and intuition
tells us,
faith in tests.
Yet finding the definitive
which can clinch
Over
feel safe.
and Sources
but
too often doctors place
all
makes both doctor and patient
a diagnosis,
the years lab testing for minerals evolved
The
testing mineral ions,
present state of the
which
There are two
art,
however,
lies in
component of
level.
clinical tests that
tor’s office, the results
to isolating min-
are the active
minerals working at the tissue
deficiency and
their
test for a condition,
from measurements done on whole blood erals inside cells.
all
can be done in a doc-
of which can indicate both calcium
magnesium
deficiency: Chvostek’s sign (a
contraction of the facial muscles caused by tapping lightly
on the
facial
sign (a a
nerve located in front of the ear) and Trousseau’s
spasm of the hand muscles caused by applying
tourniquet or blood pressure cuff to the forearm below
the
elbow for three minutes). But
since neither test distin-
calcium deficiency from magnesium deficiency,
guishes
doctors use the test to diagnose and treat only calcium deficiency.
causing
As
a result,
magnesium
levels are driven
even lower,
more symptoms.
TOTAL SERUM (BLOOD) MAGNESIUM TEST In spite of, or perhaps because of, that rely
less
than
magnesium can be measured
1
the metabolic processes
percent of our body’s
our blood; the
rest
busily occupied in the cells and tissues. Therefore,
it is
total is
on magnesium,
all
virtually impossible to extrapolate
209
in
and make an accurate
The Miracle of Magnesium
assessment of the level of magnesium in various body tissue using a routine total serum magnesium
cells
sium
blood does not correlate with the amount of
in the
magnesium under the
Magne-
test.
in other parts of
your body. In
stress of various ailments,
magnesium out of
fact, if
you
are
your body pumps
the cells and into the blood, giving the
mistaken appearance of normality on testing in spite of
bodywide
most magnesium
depletion. Unfortunately,
eval-
uations done in hospitals and in laboratories use this anti-
quated
total
serum magnesium
test.
RED AND WHITE BLOOD CELL MAGNESIUM TESTS All
up
body
cells,
including red and white blood
to 40 percent of the body’s
red blood
cell
sure of total
sium
test.
magnesium
One
first
While
of
levels
affairs.
released
somewhat more
total
levels to total
white blood
serum magnesium became elevated on the attack, the total
white blood
As mentioned above, under cells,
magnesium
levels are
levels in cells,
not
cell
and
real state
total
is
white
measures of
as are ionized
will dicuss later.
210
mag-
floods into the
as accurate
magnesium
which we
it
cell
magnesium
stress
depleting them, as
the actual tissue levels of
sium
total
magnesium
cell
dropped dramatically, indicating the
from the
cell
serum magne-
the total
bloodstream. 8 However, total red blood
blood
accurate mea-
study in childhood asthmatics compared
day of an asthma
nesium
a
contain
magnesium. Studies show that
body magnesium than
serum magnesium levels.
is
cells,
magne-
Magnesium Requirements,
Testing,
and Sources
THE MAGNESIUM CHALLENGE TEST Time-consuming and cumbersome, the magnesium
two twenty-four-hour urine
lenge test requires
The
first
collection
is
done while the patient
chal-
collections.
taking his or
is
her normal supplements. Then, in the doctor’s office, a dose of 2
meq/kg of magnesium chloride or magnesium
sulfate
given intravenously, infused over a four-hour period.
ond urine
collection begins after the
twenty-four hours. Deficiency exhibits a need for
is
diagnosed
body
stores. 9
is
test
A sec-
continued for
when
magnesium by holding on
25 percent of the magnesium given.
nesium challenge
IV and
is
to
body
the
more than
A decade ago, the mag-
was the best method of determining
However, comparison
studies using
magne-
sium challenge and ionized magnesium indicate that ionized
magnesium easily
done
testing appears to be a better indicator
and more
(see next page). 10
THE BUCCAL SMEAR
One
innovative
buccal
cell
smear
membranes on
The
test, test.
which
is
not readily available,
A scraping is
the floor of the
is
the
taken from the mucous
mouth under
the tongue.
with
total mineral levels in the buccal cells correlate
the results
from white blood
Analysis
performed using scanning electron microscopy
is
cells
and red blood
(EXA). Once
(SEM) and elemental X-ray
analysis
when compared with
magnesium
ionized
smear comes up short because
211
this test
cells.
again,
testing, the buccal is
measuring
total
The Miracle of Magnesium
cellular
magnesium
white blood
nesium
contents, as are the red blood cell and
not measuring active, free mag-
cell tests. It is
ions.
BLOOD IONIZED MAGNESIUM TEST The blood ionized magnesium
test,
tensively at the State University of
pioneered and tested ex-
New
York
by magnesium researchers
Bella and
most accurate and
magnesium blood
reliable
The Alturas have researched
in
Brooklyn
Burton Altura,
is
test available.
the health effects of
magne-
sium since the 1960s and did the original research for the in 1987. 11
The
’
the
test
12 ’ 13 ’ 14 15 16
ionic
backed up by
’
’
magnesium results
test is a
very refined procedure,
on many thousands of
patients with
over twenty-two different disease states and published in
dozens of journals, including
five
papers in Science and pa-
pers in the prestigious Scandinavian Journal of Clinical
Laboratory Investigation and
Scientific
American. 17 To de-
termine the efficacy and efficiency of the
new
test,
research
included a comparison of magnesium levels found with the Alturas’ ionized
body
magnesium
test to levels
tissues using expensive
found
and sensitive
in various
digital
imaging
microscopy, atomic absorption spectroscopy, and the mag-
nesium fluorescent probe. The blood ionized magnesium test
came through
as a
relatively inexpensive
tus in healthy or
ill
highly sensitive, convenient, and
means of determining magnesium
subjects.
212
sta-
Magnesium Requirements,
Here’s
how
ther as active
it
works. Magnesium
magnesium
and Sources
Testing,
exists in the
ions or as inactive
makes
it
is
an atom that
is
A magne-
missing two electrons, which
search to attach to something that will replace
missing electrons.
Magnesium
logically active fraction of
ei-
magnesium
complexes bound to proteins or other substances.
sium ion
body
its
ions constitute the physio-
magnesium
in the
body; they are
not attached to other substances and are free to join in biochemical body processes. 18
Most
clinical laboratories assess
only total serum mag-
nesium, which includes both active and inactive types. With the blood ionized rectly
measure the
magnesium levels of
test
now
it is
magnesium
possible to di-
ions in
whole blood,
plasma, and serum using ion-selective electrodes. 19
For example, ionized magnesium
testing
on three thou-
sand migraine patients shows that 90 percent of those with
low magnesium ion
levels
In 85 to 90 percent of levels
match
all
improve with magnesium therapy.
patients tested,
tissue levels of free
low magnesium ion
magnesium and accurately
diagnose magnesium deficiency found in asthma, brain trauma, coronary artery disease, types gestational diabetes, eclampsia ease,
I
and
II
diabetes,
and preeclampsia, heart
dis-
homocysteinuria, hypertension, tension headaches,
posttraumatic
headaches,
transplant patients,
renal
ischemic
heart
transplant patients,
ovarian disease, stroke, and syndrome X. In conditions,
disease,
low magnesium ion
213
levels
polycystic
many
exist
liver
in
of these spite
of
The Miracle of Magnesium
normal
serum magnesium
total
magnesium diagnosis
more
test
making the ionized
levels,
magnesium deficiency
reliable for
20 21 22 23 24 25 26 27 28 29 .
’
’
’
’
’
’
’
’
’
The FDA-approved ionized magnesium
being
test is
ordered by more and more doctors as they become familiar
with the dozens of research papers confirming
The
testing continues to be
performed
its
efficacy.
in a handful of labs,
including the Alturas’ laboratory, with blood samples ing in
from
all
over the United States
some research
spate of testing in
trodes produced inferior results.
30 .
A
com-
few years back
a
labs using inferior elec-
The
will provide the test to doctors for a fee
Alturas, therefore,
and
at the
same time
help other clinical labs set up the right protocol and equip-
ment
to
do
their
own
ionized magnesium testing properly.
(See the Resources section for further information
ionized magnesium
on the
test.)
THE ORAL CLINICAL TRIAL For the average individual, the ionized
magnesium
sium deficiency three in
is
who
test,
one way to diagnose magne-
simply to try supplementing. For one to
months take magnesium while recording
your physical and mental
under
does not have easy access to
health. It
may
all
be best to do
a health professionals guidance, especially
on medications or have an
changes
if
this
you
existing medical condition.
are
The
alleviation of
symptoms
tutes the best
proof that you had a magnesium deficiency.
after thirty to ninety
214
days consti-
Magnesium Requirements,
See
Testing,
“Magnesium Supplements,” page
and Sources
228, for types of
mag-
nesium and dosage.
FALSE POSITIVE MAGNESIUM TESTS The
lack of adequate tools to measure
hospitals and clinics
not prescribe
worse than normal
it.
A
is
in
most
another reason medical doctors do
total
ineffective,
magnesium
serum magnesium
because a
test result that
limits lends a false sense of security
of the mineral in the body.
It
test is actually
within
is
about the status
also explains
why
doctors
don’t recognize magnesium deficiency; they assume total
serum magnesium
levels are
sium researchers mostly use cell
magnesium
tests to
an accurate measure. Magne-
total
serum and
total red
determine magnesium
blood
status.
they begin to use the more accurate ionized magnesium
As test,
however, the results will indicate even more widespread deficiency in the population.
DIET SOLUTIONS TO
MAGNESIUM DEFICIENCY Good
nutrition creates a solid foundation of tissue and
bone. The basis of good nutrition minerals, trace minerals, vitamins, fatty acids. Clearly there
but
life
can’t exist
without
To enrich your
diet
more
is
is
the consumption of
amino to
acids,
life
and
essential
than magnesium,
it.
with magnesium, increase your
215
The Miracle of Magnesium
consumption of green vegetables,
nuts, seeds, legumes,
and
unprocessed grains. Removing the germ of cereals and the outer seed husks through processing eliminates most of the
magnesium present
in the
whole
grain. It
a
is
good
idea to supplement a diet of fruit and protein-rich foods
such
as fish, meat,
and milk by eating wheat germ, kelp,
brewer’s yeast, sunflower seeds, salt,
which
are
and sea
seeds,
extremely rich in magnesium. Since one of
you may be magnesium-deficient
the reasons
too
all
pumpkin
much cooked
food, try to eat
nately, nuts, seeds,
more raw
is
from eating
foods. Fortu-
and many vegetables can be eaten raw,
and raw wheat germ can be used on cereal and
in protein
drinks.
According to top French magnesium experts, highly and blood vessel-protective
fective heart-
saturated
fats,
fatty acids
diets that
increase monounsaturated fat and
(from
fish
and
flaxseed), limit the
ef-
reduce
omega-3
consumption
of alcohol, and increase the intake of cereals, fruits, vegetables, fish,
sium.
and low-fat dairy products that are rich
They
among
stress that
magnesium should be given
in
magne-
several protective nutrients,
particular consideration because
of the very frequent occurrence of chronic primary magne-
sium deficiency, which
acts as a cardiovascular risk factor. 31
ORGANIC FOOD Factory-farmed food organic food
is
a
is
deficient in
wiser choice.
magnesium; therefore,
As more people go
216
this route,
Magnesium Requirements,
Testing,
and Sources
whether to avoid herbicide and pesticide residues or to ensure nutrient-dense produce, the cost of organic food
dropping dramatically. However, organic food antee of higher
who
magnesium
The smart way
to join a tive
soil,
not
a
guar-
Seek out organic farmers
about crop rotation,
are educated
mineral deficiencies in the ers.
levels.
is
is
test regularly for
and use mineral-rich
fertiliz-
to be assured of quality organic food
is
community-sponsored agriculture (CSA) coopera-
and buy
farm every
a share in a local organic
year.
Every week for an average of twenty-four weeks you share the harvest,
which can include fresh vegetables,
and
fruit,
free-range eggs, chicken, and lamb. (See the Resources section for contact information
on CSAs.)
USDA FINDINGS The United
States
Department of Agriculture (USDA)
sur-
veys of women’s diet find that approximately 25 percent of
magnesium
their
you should
is
supplied by grain products. This means
try to include a variety of
avoid refined white bread and pasta.
whole grains and
(If
you crave sugar
and bread, you might be addicted to carbohydrates and should try to limit your intake to achieve weight loss and
blood sugar balance.) Another 25 percent of magnesium take
comes from
foods
fruits
and vegetables. The high-protein
—meat, poultry, and
cent of total
magnesium
in-
fish
— provide only about 18 per-
intake. Since protein diets are
becoming more popular, you must make sure
217
now
to increase
The Miracle of Magnesium
your intake of magnesium when on such
a diet. Fats, sweets,
and beverages supply 14 percent of the
magnesium
total
intake; however, these foods, especially refined fats
sweets, should be limited because they contain
calo-
from nuts and seeds
ries
devoid of nutrients. Natural
and
their butters are the richest sources of
fats
empty
and
magnesium, but
they are not even mentioned in most food surveys.
MAGNESIUM SOURCES In the their
Appendix you
magnesium
will find a
content. Flere
sources of magnesium. 32 these sources figures as a
The
were assayed
is
complete
list
of foods with
a short
list
of the richest
is
quality of the soil
from which
unknown. Therefore, use
these
rough guide to making magnesium-wise food
choices.
MAGNESIUM CONTENT OF SELECTED FOODS (mg per 3V2 oz [100 g/10
tbsp] serving)
Kelp
760
Wheat bran
490
Wheat germ
336
Almonds
270
Cashews
267
218
Magnesium Requirements,
Testing,
and Sources
Molasses
258
Yeast, brewer’s
231
Buckwheat
229
Brazil
225
nuts
Dulse
220
Filberts
184
Peanuts
175
Wheat
160
grain
Millet
162
Pecan
142
English walnuts
131
Rye
115
Tofu
111
HERB SOURCES OF MAGNESIUM Green
plants,
cilantro, are
other
including most herbs, like purslane and
loaded with magnesium
33 34 35 36 .
’
commonly used magnesium-rich
introduce into your
diet.
’
’
Here
are
some
herbs that you can
Herbs have the added advantage
of being mostly organic or picked wild, so they usually
don’t contain pesticides and herbicides.
BURDOCK ROOT (ARCTIUM LAPPA) 537 MG MAGNESIUM PER 100 G Master herbalist Matthew as a diuretic for
Wood describes burdock root
kidney gravel, an excellent blood cleanser,
219
The Miracle of Magnesium
can be grated into salads or cooked
and
a liver detoxifier. It
like
potato and eaten several times per week.
CHICKWEED (STELLARIA MEDIA) 529 MG MAGNESIUM PER 100 G Herbalist Susun
Weed
describes chickweed as a perfect
food with “optimum nutrition.” Chickweed encourages absorption of minerals and nutrients and high in magnesium. Used several times a
also naturally
is
week
in salads,
it
provides an excellent source of dietary magnesium.
DANDELION (TARAXACUM OFFICINALE) 157 MG
MAGNESIUM PER 100
G
This amazing herb has been
but
its
vilified as a
nuisance weed,
healing properties are legion. According to
Chevallier, an experienced medical herbalist, a diuretic to treat
it
is
Andrew used
as
high blood pressure, and as a detoxifier
removing waste products from the gallbladder and the kidneys, thereby ameliorating
many
conditions such as gall-
stones, constipation, acne, eczema, arthritis,
doubt
it
owes some of
its
and gout.
actions to the properties of
No
mag-
nesium. Dandelion leaves, used in salads, add a necessary bitter
property that stimulates the
cooked or grated raw into
salads.
220
bile.
The root can be
Magnesium Requirements,
Testing,
and Sources
DULSE (PALMARIA PALM ATA) 220 MG MAGNESIUM PER 100 G
There are many forms of dulse or seaweed, and
all
are
very nutritional. They are very high in digestible protein,
around 25 percent by weight. Iodine to support the thyroid gland
is
their
most notable
benefit.
They
are high in
most
minerals as well as vitamins. Dulse can be introduced several times a
week
tarian sushi rolls,
in
soups and stews, and don’t forget vege-
which
are
wrapped
in
seaweed.
NETTLES (URTICA DIOICA) 860 MG MAGNESIUM PER 100 G Nettles are used to soften gallstones or kidney stones in the body. Susun in her
Weed
has
some
excellent recipes for nettles
book Healing Wise When .
nettles are lightly
they lose their stinging properties and
make an
steamed excellent
vegetable addition to any meal.
MINERAL WATER AND MAGNESIUM
An
important source of magnesium, popular in Europe,
magnesium-rich mineral water.
We
have only
a
few
is
local
waters in the United States that have high magnesium levels that could help to reduce
magnesium
deficiency.
We
must
also be careful to consider the calcium content of bottled
water in relation to magnesium. tells
A
close reading of labels
us that calcium and sodium are usually
much
higher
than magnesium. Therefore, choose water with calcium no
more than twice
the level of magnesium. This will ensure
221
The Miracle of Magnesium
you
that
are getting
you know you have
enough of both minerals. a
magnesium
deficiency,
If,
however,
by symptoms
or by medical or naturopathic diagnosis, choose water with
high magnesium and low calcium content for replacement.
And
if
you
suffer
from heart
disease,
choose mineral water
with low sodium content. Be aware that even though says “mineral water,” the mineral contents cule and not
worth the
price
Name
Country
Adobe Springs
USA
Santa Ynez
USA
be minus-
you pay 37 .
MAGNESIUM Water
may
a label
IN
WATER 38
Magnesium
Calcium
Sodium
(mg/L)
(mg/L)
(mg/L)
96
3.3
5
87
19
—
57
203
46
159
/•
San
Pellegrino
ITALY
(
V
j
Penafiel
MEXICO
41
131
Vittel
FRANCE
38
181
\ Evianj
FRANCE
24
78
5
Naya
CANADA
22
38
6
Volvic
FRANCE
7
3.7
10
10.7 •
i
Saratoga
USA
7
64
Perrier
FRANCE
5
143
9 15.2 »
Alhambra
USA
5
Arrowhead
USA
5
Sparkletts
USA
5
4.6
Calistoga
USA
2
8
Cobb Mountain
USA
2
5.6
f
222
9.5
20
5.4
3 15.2
163 4.6
Magnesium Requirements,
Testing,
and Sources
/
Water
Name
Country
Magnesium
Calcium
Sodium
(mg/L)
(mg/L)
(mg/L)
8.9
Poland Spring
USA
2
13.2
Sante
USA
1
4.2
Black Mountain
USA
1
USA
1
Crystal
Geyser
223
25 1.5
160 8.3
30
CHAPTER
13
Supplementation and Homeopathics
When you take supplements it can be a real challenge to find out how much actual or elemental magnesium is available in each pill or capsule. in nature but
Magnesium does not
exist alone
comes combined with other substances. That
other substance, tagging along with magnesium, has a specific
weight. Presently,
I
take
two 500
mg
capsules of
nesium oxide, but each capsule does not contain 500 magnesium. Only 60 percent of is
a
absorbing only
mg is
half; half
two 500 mg capsules sium.)
My
above the
give
300 mg. of 300
me
RDA
for
Of that
mg
gives
300 mg,
me
300
is
I
may
be
150 mg. (So,
mg
of magne-
200 mg, putting
women, which
224
of
the attached oxide.
is
a total of
diet supplies another
mg
magnesium oxide capsule
magnesium; the other 40 percent
Sixty percent of 500
mag-
me
well
320 mg. Some days,
Supplementation and Homeopathics
when
my my
I
am under
significant stress,
mg magnesium
normal two 500
bowel movements
back to two per day.
I
get soft
I
take three instead of
and unformed,
also switch brands
of
magnesium every few months
so
I
When
oxide capsules.
to give
know
I
to go
and switch types
my body
a
change
don’t get used to any one type of magnesium, and to see
what works best There bels,
is
which
for me.
one more thing to be aware of on product
the specification of dosage. All too often peo-
is
ple will find that they have to take not
make up
tablets to
the dosage
small print, but read
it
on the
one but three or label. It
may
carefully to understand exactly
what
MAGNESIUM DOSAGE To individualize your
men
magnesium dosage, the
6-8 mg/kg
is
rule of
of
600
to
searchers
900 mg
of their low body weight
stress
and
magnesium
per day for a 200-lb man.
recommend 10 mg/kg/day
growth and
thumb
(3.0 to 4.5 mg/lb) of body weight
per day. That translates into a total dietary
Some
for children
6-10 mg/kg/day
training levels. 1
-
2 3 4 -
-
225
for athletes,
re-
because
and increased requirements
six
be in
each tablet contains.
for
la-
for
depending on
The Miracle of Magnesium
CONTRAINDICATIONS TO MAGNESIUM THERAPY 1.
2.
Kidney
failure. With kidney failure there
to clear
magnesium from the
is
an
inability
kidneys.
Myasthenia gravis. Intravenous administration could accentuate muscle relaxation and collapse the respiratory muscles.
3.
Excessively slow heart rate. Slow heart rates can be
made even
magnesium
slower, as
Slow heart rates often require an 4.
Bowel obstruction. The main oral
magnesium
is
relaxes the heart.
artificial
pacemaker.
route of elimination of
through the bowel.
THE SAFETY OF MAGNESIUM SUPPLEMENTS For the average person, dosages, has
mechanism
no
oral
side effects except loose stools,
to release excess
cut back. Excess
magnesium, even
magnesium and an
magnesium
is
also lost
in
which
high is
a
indication to
through the urine.
TYPES OF MAGNESIUM Bone meal
is
cent of the
magnesium
is
in the
a rich source of
bones and
90, along
magnesium. More than 60 per-
in the bodies of
humans and animals
teeth. Since 1945, radioactive
strontium
with lead and a variety of other toxic elements, be-
226
Supplementation and Homeopathics
gan to show up
our bones and in the bones of
in
which bone meal
is
produced.
find an organic source of
you wish
It is
other reason
makes good sense
this
An-
product.
to use only organic animal
mad cow
up
in
Chelated magnesium, bound to organic amino acids,
is
products this
to
assayed for
strictly
consume
if
it
important, therefore, to
bone meal,
contaminants,
from
cattle
is
the possibility of
disease turning
country in the future.
said to be better
absorbed but
is
more
expensive.
Comple-
mentary medicine practitioners rely on chelated magnesium, such
as
magnesium
glycinate, to treat serious cases of
mag-
nesium deficiency. Weight for weight and dollar for oxide
may
magnesium
dollar,
be the best buy for general use.
TYPES OF MAGNESIUM
Inorganic salts
Organic salt chelates
Magnesium oxide
Magnesium
Magnesium carbonate
Magnesium aspartate
Magnesium
chloride
Magnesium glutamate
Magnesium
sulfate
Magnesium adipate
glycinate
Magnesium phosphate
Magnesium
citrate
Magnesium bicarbonate
Magnesium
orotate
Magnesium taurate
Magnesium
227
lysinate
The Miracle of Magnesium
MAGNESIUM CONTENT OF VARIOUS SUPPLEMENTS Magnesium
Amount
Salt
of Elemental
Magnesium per 500 mg
Magnesium oxide
300 mg
Magnesium carbonate
150 mg
Magnesium
Salt
60 mg
chloride
75 mg
Dolomite
Magnesium
lactate
60 mg
Magnesium
glycinate
50 mg
Magnesium
sulfate
50 mg 25 mg
Magnesium gluconate
WHEN TO TAKE MAGNESIUM I
take
the
my
first
dose of magnesium
morning and the
last
dose
at
when
bedtime.
dose, that will be in the late afternoon. deficient in the early
people
feel that
morning and
magnesium
keeps them awake
at night.
is
night and find that
it
If I
Magnesium
late
Others,
helps
who
is
afternoon.
feel
most
Some
it
relax
it
helps their
muscle tension, take
them
in
take a third
sufficiently energizing that
leg cramps, fibromyalgia, or general at
wake up
I
and sleep
it
well.
There are so many ways that magnesium can" work on the
body
that
it is
important for you to decide what timing
best for you.
228
is
Supplementation and Homeopathics
CALCIUM AND MAGNESIUM INTERACTION Watch your calcium cium
A
that too
much
cal-
impede magnesium uptake and function. Push
will
aside the media-generated facts.
We know
intake.
hype on calcium and look
thousand years ago our
diet favored
at
the
magnesium
over calcium. Current research seems to indicate that three parts calcium to
magnesium
parts
is
probably most
with average optimal amounts of calcium
beneficial,
1,000
two
mg per day and magnesium
at
at
600 mg. 5
MAGNESIUM INTERACTION WITH OTHER NUTRIENTS Magnesium
is
extremely important for the metabolism of
calcium, potassium, phosphorus, zinc, copper, iron, sodium, lead,
cadmium, hydrochloric
acid, acetylcholine,
and
nitric
oxide, as well as for the activation of vitamin B! and therefore for a very shift in
sium
crucial
body
functions. 6
A
any one of these nutrients has an impact on magne-
levels
body and late
wide spectrum of
and vice
all its
versa. It
components
one substance to
is
the interwoven nature of the
that
makes
scientifically
Magnesium cannot be taken out
it
so difficult to iso-
“prove” what
magnesium
intake
is
necessary to convert
D into one of the hormones that makes effi-
cient use of calcium in
creases the
you should
when you consume more phos-
phorus and vitamin D. Magnesium dietary vitamin
can do.
of context either in a re-
search setting or in your body. For example, increase
it
amount
of
bone formation. 7 8 Vitamin B 6 ’
magnesium
231
in-
that can enter cells; as a
The Miracle of Magnesium
result, these
two
nutrients are often taken together. In one
experiment, serum vitamin 9
sium supplementation
.
E
We
levels
also
improved
know
that
after
magne-
magnesium and
the essential fatty acids (EFAs, found in fish, nuts and seeds,
and flaxseed efficiently
oil) are
when
interdependent; each works
the other
is
present in sufficient amounts.
HOMEOPATHIC MAGNESIUM: ANOTHER FORM OF MAGNESIUM Developed by Samuel Hahneman in the early century,
homeopathy
is
a natural
amounts
toms similar
if
given in a toxic amount, can cause symp-
to those that the patient
two hundred years of
is
attribute
symptoms. After
use and observation, home-
now more successful than the tools we have measure how it works. Although skeptics
avail-
which
a pa-
its
success to the placebo effect, in
tient’s belief in
lions
clinical
experiencing, but
is
able to
wa-
Research has shown that
that the infinitesimal dose can cure those
opathy
in alcohol or
in order to stimulate the indi-
vidual’s natural healing response.
these medicines,
nineteenth
medical science that uses
mostly plants and mineral extracts diluted ter to infinitesimal
much more
who
often
an outcome produces that outcome, the mil-
have benefited from homeopathy include infants
and animals, two groups that are clearly not susceptible to the placebo effect.
Nonetheless, in America homeopathy continues to be marginalized in favor of other drugs, even in the face of
232
Supplementation and Homeopathics
such early evidence
as the influenza
which the homeopathic
epidemic of 1919, in
hospitals in
England showed
a
greater cure rate than conventional hospitals. In Europe,
both homeopathic medicine and herbal medicine enjoy
a re-
spected place in the health care system.
Homeopathic remedies 12 or 30
6,
ber,
the
X (10)
C
or
typically
(100) potency.
dilution and
greater the
come
in dosages of
The higher
the
the
num-
more potent
the
remedy. Usually, you take three pellets or four drops of
remedy
several times a day.
For
a
very acute, painful symp-
tom, a dose can be taken every fifteen minutes. However, after taking five or six doses of a
symptoms, the remedy
in
should seek a
is
new remedy. Be
wrong remedy
a half
a
remedy
there
is
if
no change
probably ineffective and you assured that treating with the
dozen times does not cause any nega-
tive side effects.
In homeopathy,
magnesium
is
used primarily for acute
muscle spasms or chronic complaints. 10 Please consult a
homeopath
for a
more
detailed evaluation of
your
case.
MAGNESIA PHOSPHORICA Magnesia phosphorica (magnesium phosphate, or mag phos) is
a great
antispasmodic remedy and the most
magnesium homeopathic remedy. all
It
commonly used
readily treats cramping of
muscles, including hiccups, leg cramps, writer’s cramp, ab-
dominal
colic, heart pain,
lung pain, menstrual pain accom-
panied by radiating pains, neuralgic pains, and
233
all
sorts of
The Miracle of Magnesium
and tremors including twitching of the
tics
especially well in debilitated subjects
and physically
who
eyelids. It
are
works
both mentally
tired.
Dr. Margery Mullins, an internist and acupuncturist, recently wrote to the use of
tell
me
about the success she has had with
magnesium phosphate (mag phos)
spasms. She said patients would get instant didn’t
seem to need the remedy
after their
relief
patients, a nine-year-old girl,
and then
magnesium
ciency was corrected with diet and supplements.
young
for muscle
One
defi-
of her
was having such severe
muscle spasms that she was referred to a pediatric neurologist.
In the interim, Dr. Mullins gave her Magnesia phos-
phorica 6X, and by the time of her appointment with the specialist the child
noted that the
no longer had the problem. Dr. Mullins
girl’s
mother had had toxemia (eclampsia)
during her pregnancy, requiring intravenous magnesium.
234
Appendix
MAGNESIUM CONTENT OF SELECTED FOODS (in
mg
per 3V2 oz [100
g] serving)
Kelp
760
Wheat bran
490
Wheat germ
336
Almonds
270
Cashews
267
Molasses
258
Yeast, brewer’s
231
Buckwheat
229
Brazil
225
nuts
Dulse
220
Filberts
184
235
Appendix
Peanuts
175
Millet
162
Wheat
160
grain
Pecan
142
English walnuts
131
Rye
115
Tofu
111
Coconut meat, dried
90
Brown
rice
88
Soybeans, cooked
88
Figs, dried
71
Apricots
62
Dates
58
Collard greens
57
Shrimp
51
Corn, sweet
48
Avocado
45
Cheddar cheese
45
Parsley
41
Prunes, dried
40
Sunflower seeds
38
Barley
37
Beans, cooked
37
Dandelion greens
36
Garlic
36
Raisins
35
Green peas, fresh
35
Potato with skin
34
236
Appendix
Crab
34
Banana
33
Sweet potato
31
Blackberry
30
Beets
25
Broccoli
24
Cauliflower
24
Carrot
23
Celery
22
Beef
21
Asparagus
20
Chicken
19
Green pepper
18
Winter squash
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Eggplant
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Tomato
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Milk
13
237
Resources
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241
Clinical
References
INTRODUCTION 1. Aikawa JK, Magnesium:
Its Biologic Significance,
CRC
Press,
Boca
Raton, FL, 1981 2.
Iannello
S,
Belfiore F, “Flypomagnesemia.
logical, clinical
A
review of pathophysio-
and therapeutical aspects.” Panminerva Med,
vol. 43,
no. 3, pp. 177-209, 2001 3.
Altura
BM,
“Introduction: importance of
Mg
in
physiology and
medicine and the need for ion selective electrodes.” Scand ] Clin Lab Invest Suppl, vol. 217, pp. 5-9, 1994 4.
Institute of Medicine, Dietary Reference Intake for Calcium, Phos-
phorus, Magnesium, Vitamin D, Press,
and
Fluoride, National
Washington DC, 1997
5.
Durlach J, Magnesium
6.
Fehlinger R, “Therapy with magnesium eases.”
7.
Academy
Magnes
Ducroix
Bull, vol. 12, pp. 35-42,
T, “L’enfant
peutiques.”
in Clinical Practice,
Magnes
spasmophile
Bull, vol.
1,
Libbey, London, 1988 salts in
1990
—Aspects diagnostiques
pp. 9-15, 1984
242
neurological dis-
et thera-
References
CHAPTER 1.
1
BM,
Altura
Altura BT, “Cardiovascular risk factors and magnesium:
relationships to atherosclerosis, ischemic heart disease and hyperten-
Magnes Trace Elem, vol. 92, no. 10, pp. 182-192, 1991 Eisenberg MJ, “Magnesium deficiency and sudden death.” Amer
sion.” 2.
Heart J, 3.
544-549, 1992
vol. 124, no. 2, pp.
Turlapaty PD, Altura
BM, “Magnesium
deficiency produces spasms
of coronary arteries: relationship to etiology of sudden death
chemic heart disease.” Science 4.
Altura
BM, “Sudden-death
nesium
intake:
is
Med Hypotheses 5.
Karppanen
H
coronary death.” 6.
198-200, 1980
vol. 208, no. 4440, pp.
ischemic heart disease and dietary mag-
the target site coronary vascular vol. 5, no. 8, pp.
et
is-
smooth muscle?”
843-848, 1979
“Minerals, coronary heart disease and sudden
al.,
Adv
Cardiol, vol. 25, pp. 9-24, 1978
Rogers SA, Depression Cured at Last
,
SK
Publishing, Sarasota, FL,
2000 7.
Henrotte JG, “Type nesium, vol.
8.
Cernak
I,
5,
A
behavior and magnesium metabolism.”
pp. 201-210, 1986
et ah,
“Alterations in
ing chronic emotional stress.” ~ 9.
magnesium and oxidative
Magnes
Res, vol. 13, no.
status dur-
1,
pp. 29-36,
2000
Goldberg B, Alternative Medicine Guide: Future Medicine Publishing, Tiburon,
10.
Mag-
Aikawa JK, Magnesium:
Its
Women
’
s
Health Series
1,
CA, 1998
Biologic Significance,
CRC
Press,
Boca
Raton, FL, 1981 11.
Levine BS, Coburn JW, “Magnesium, the mimic/antagonist of cium.”
12.
N Engl J Med, vol. 310, pp.
LT, French JH,
Iseri
13.
Seelig
sium
ment of
reactions to stress intensified
by magne-
consequences of magnesium deficiency on the enhance-
stress reactions; preventive
review.” J 14.
108, pp. 188-193, 1984
MS, “Cardiovascular
deficit in
1253-1255, 1984
“Magnesium: nature’s physiologic calcium
Am Heart ], vol.
blocker.”
cal-
Am CollNutr, vol.
and therapeutic implications:
13, no. 5, pp.
429-446, 1994
Rodale JR, Magnesium: The Nutrient That Could Change Your Rodale Press, Emmaus,
PA
1971
243
a
Life,
References
15.
Hartwig A, “Role of magnesium
genomic
in
Mutat Re-
stability.”
search, vol. 18, no. 475 (1-2), pp. 113-121, 2001 16.
CC, Zinc and Other
Pfeiffer
Micro-Nutrients, Keats,
New
Canaan,
CT, 1978 17.
GM,
Walker
“Biotechnological implications of the interactions be-
tween magnesium and calcium.” Magnes Res,
vol. 12, no. 4, pp.
303-309,
1999 18.
Altura
BM, “Sudden-death
nesium
intake:
is
Med Hypotheses, 19.
ischemic heart disease and dietary mag-
the target site coronary vascular vol. 8, pp.
smooth muscle?”
843-848, 1979
New
Eades M, Eades A, The Protein Power Lifeplan, Warner Books, York, 1999
CHAPTER 1.
2
Kant AK, “Consumption of energy-dense, nutrient-poor foods by adult Americans: nutritional and health implications. tional
4,
Na-
Am ]
pp. 929-936, 2000
Institute of Medicine, Dietary Reference Intake for Calcium, Phos-
phorus, Magnesium, Vitamin D, Press, 3.
third
Health and Nutrition Examination Survey, 1988-1994.”
Clin Nutr, vol. 72, no. 2.
The
and
Fluoride, National
Academy
Washington DC, 1997
Werbach MR, Nutritional Influences on Illness, Thorstons Publishing Group, Wellingborough, Northamptonshire, 1989.
4.
Ibid.
5.
Eades M, Eades A, The Protein Power Lifeplan, Warner Books,
New
York, 1999 10. 6.
Ibid.
7.
Worwag M,
Classen
and zinc deficiencies
HG, Schumacher in nursing
home
E, “Prevalence of
residents in
magnesium
Germany.” Magnes
Res, vol. 3, pp. 181-189, 1999 8.
Linderman RD, “Influence of various nary divalent cation excretion.”
nutrients and
Ann NY Acad Sci,
hormones on
vol. 162, pp.
uri-
802-809,
1969 9.
Lemann
J et ah,
“Evidence that glucose ingestion inhibits net renal
tubular reabsorption of calcium and
magnesium
in
man J Lab
Clin
Medicine, vol. 75, pp. 578-585, 1970
Abbot L
et
al.,
“Magnesium
deficiency in alcoholism: possible con-
244
References
tribution to osteoporosis and cardiovascular disease in alcoholics.”
Alcohol Clin Exp Res, vol. 11.
Barbagallo
19, pp.
M, Dominguez
1076-1082, 1994
LJ, Resnick
LM,
“Insulin-mimetic action
of vanadate: role of intracellular magnesium.” Hypertension, vol. pt. 2,
pp. 701-704, 2001
12. Physicians’
Desk Reference. 56th
ed.
Medical Economics, 2002.
13.
Ibid.
14.
Crossen C, Tainted Truth: The Manipulation of Schuster, New York, 1995
15.
Teo
KK et
“Effects of intravenous
al.,
magnesium
myocardial infarction: overview of randomized vol. 303, pp. 16.
3,
Fact.
Simon
&
in suspected acute
Med J,
trials.” Brit
1499-1503, 1991
Teo KK, Yusuf
“Role of magnesium
S,
A
myocardial infarction.
in
reducing mortality in acute
review of the evidence.” Drugs, vol. 46,
pp. 347-359, 1993 17.
Altura
BM, “Sudden-death
nesium
intake:
is
Med Hypotheses, 18.
BM,
Altura
ischemic heart disease and dietary mag-
the target site coronary vascular vol. 5, no. 8, pp. 843-848,
smooth muscle?”
1979
“Introduction: importance of
Mg
in
physiology and
medicine and the need for ion selective electrodes.” Scand J Clin Lab Invest Suppl, vol. 217, pp. 5-9, 1994 1
9.
Mauskop A, Fox graines.
20.
A et
magnesium
21.
What Your Doctor May Not
Warner Books,
Mauskop ratio.”
B,
al.,
A
Mauskop
et
You About Mi-
New York, 2001
“Deficiency in serum ionized magnesium but not total
in patients
Headache,
Tell
with migraines. Possible role of ICa2+/IMg2 +
vol. 33, no. 3, pp. 135-138,
al.,
1993
“Intravenous magnesium sulphate relieves mi-
graine attacks in patients with
low serum ionized magnesium
levels: a
pilot study.” Clin Sci (Colch), vol. 89, no. 6, pp. 633-636, 1995 22. Seelig
MS, “The requirement
Am J Clin Nutr, vol. 23. Seelig
sium
14, pp.
MS, “Cardiovascular
deficit in
ment of Durlach
25.
Durlach
magnesium by
reactions to stress intensified
Magnesium
J,
by magne-
consequences of magnesium deficiency on the enhance-
Am Coll Nutr, vol.
J,
the normal adult.”
342-390, 1964
stress reactions; preventive
review.” J 24.
of
“Diverse
and therapeutic implications:
13, no. 5, pp.
429-446, 1994
in Clinical Practice,
applications
245
of
a
Libbey, London, 1988
magnesium
therapy,”
in
References
Handbook of Metal-Ligand Bioinorganic Medicine vol. ,
CHAPTER 1.
Klerman GL, Weissman vol. 261, no. 15, pp.
Weissman
MM,
Marcel Dekker,
Biological
New York,
Fluids
—
1995
MM,
“Increasing rates of depression.”
2229-35, 1992
“Cross-national epidemiology of major depression
and bipolar disorder 3.
in
3
JAMA, 2.
2,
Interactions
Murphy JM, “A sion: the Stirling
.
”
JAMA,
vol. 276, no. 4, pp. 293-9,
1996
40-year perspective on the prevalence of depres-
County Study.” Arch Gen
Psychiatry, vol. 57, no. 3,
pp. 209-215, 2000 4.
5.
RR, “Sudden death in a patient on a liquid protein diet.” New Engl J Med, vol. 298, pp. 1005-1007, 1978 Werbach MR, “Nutritional influences on aggressive behavior,” JourMichiel
nal of Orthomolecular Medicine, vol. 6.
7,
Rogers SA, Depression Cured at Last,
1995
no.
1,
SK
Publishing, Sarasota, FL,
2000 7.
Durlach
J,
“Diverse applications of magnesium therapy,” in
book of Metal- Ligand Interactions in Biological Fluids Medicine vol. 2, Marcel Dekker, New York, 1995
Hand-
— Bioinorganic
,
8.
MS, “Mechanisms of interactions of stress, stress hormones and magnesium in consequences of magnesium deficiency on the enSeelig
hancement of
stress reactions; preventive
tions: a review.” 9.
Cernak
J Am Coll Nutr, vol. 13, no. 5, pp. 429-446, 1994 Alterations in magnesium and oxidative status dur-
“ I et al.,
ing chronic emotional stress.” 10.
Classen oral
11.
HG
noise
F,
Canalis
P,
“Coping with acute
stress reaction
Bull, vol. 17, pp. 1-8,
Tomasi PA, Casu
F,
Pettinato
S,
by
plentiful
1995
“The
effect of
Med (Lond),
vol. 51, no. 1, pp.
in
hu-
56-61, 2001
Starobrat-Hermelin B, Kozielec T, “The effects of magnesium physiological
supplementation on hyperactivity in children with attention
deficit hyperactivity disorder
sium 13.
Res, vol. 13, pp. 29-36, 2000
on serum and urinary magnesium and catecholamines
mans.” Occup 12.
et ah,
Magnes
magnesium supply.” Magnes
Mocci
and therapeutic implica-
oral loading test.”
(ADHD).
Magnes
Positive response to
magne-
Res, vol. 10, no. 2, pp. 149-156, 1997
Galland L, Superimmunity for Kids, Bantam Doubleday Dell, York, 1988
246
New
References
14.
Rogers SA, Depression Cured at Last
SK
Publishing, Sarasota, FL,
2000 15.
Crosby gle
V,
Wilcock A, Corcoran R, “The safety and efficacy of
dose (500
mg
or
1
g) of
a sin-
intravenous magnesium sulfate in neuro-
pathic pain poorly responsive to strong opioid analgesics in patients
with cancer.”/ Pain Symptom Management vol. 16.
Seelig
MS,
“Athletic stress, performance and
1,
pp. 35-39, 2000
magnesium
quences of magnesium deficiency on the enhancement of
17.
tions; preventive
and therapeutic implications:
Nutr, vol. 13, no.
5,
NM,
18.
Ibid.
19.
Seelig
Kills,
J
Am
Coll
Health Press, Sante
1997
MS,
“Athletic stress, performance and
magnesium
quences of magnesium deficiency on the enhancement of tions; preventive
and therapeutic implications:
Nutr, vol. 13, no.
5,
20. Singh
stress reac-
pp. 429-446, 1994
Blaylock RL, Excitotoxins: The Taste That Fe,
a review.”
in conse-
a review.”
in conse-
stress reac-
J
Am
Coll
pp. 429-446, 1994
RB, “Effect of dietary magnesium supplementation
in the
prevention of coronary heart disease and sudden cardiac death.”
Magnesium Trace Elem, 21.
Stendig-Lindberg G, “Sudden death of
term changes in serum magnesium, Clin Physiol Pharmacol, vol.
CHAPTER 1.
3,
lipids
athletes:
is
it
due to long-
and blood sugar?” / Basic
no. 2, pp. 153-164, 1992
4
Blaylock RL, Excitotoxins: The Taste That Fe,
1990
vol. 9, pp. 143-151,
NM,
Kills,
Health Press, Sante
1997
2.
Ibid.
3.
Eades M, Eades A, The Protein Power Lifeplan, Warner Books,
New
York, 1999 4.
MS, “Review and hypothesis: might patients with chronic fasyndrome have latent tetany of magnesium deficiency.” / Chron
Seelig
tigue
Fatigue Syndr, vol. 5.
4,
no. 2, pp. 77-108, 1998
Weaver K, “Magnesium and migraine.” Headache,
vol. 30, p. 168,
1990 6.
Mauskop A, Fox graines,
B,
What Your Doctor May Not
Warner Books,
New York, 2001
247
Tell
You About Mi-
References
v >
7.
A et
Mauskop
magnesium ratio.” 8.
al.,
“Deficiency in serum ionized magnesium but not
in patients
Headache,
A
Mauskop
total
with migraines. Possible role of ICa2+/IMg2 +
vol. 33, no. 3, pp. 135-138,
1993
“Intravenous magnesium sulphate relieves mi-
et al.,
graine attacks in patients with
low serum ionized magnesium
levels: a
pilot study.” Clin Sci (Colch), vol. 89, no. 6, pp. 633-636, 1995 9.
Mauskop A, Altura BT
et
“Intravenous magnesium sulfate
al.,
rapidly alleviates headaches of various types.” Headache, vol. 36, no. 10.
3,
pp. 154-160, 1996
Mauskop A, Altura BM, “Role
of
magnesium
and treatment of migraines.” Clin Neurosci,
in the pathogenesis
vol. 83, no. 5, pp.
24-27,
1998 11.
A
Mauskop
“Intravenous magnesium sulfate relieves cluster
et al.,
headaches in patients with low serum ionized magnesium
Headache, 12.
vol. 35, no. 10, pp.
Mauskop A, Altura BT
et
levels.”
597-600, 1995 al.,
“Intravenous magnesium sulfate
rapidly alleviates headaches of various types.” Headache, vol. 36, no. 13.
3,
pp. 154-160, 1996
C
Peikert A, Wilimzig
et al.,
“Prophylaxis of migraine with oral mag-
nesium: results from a prospective, multi-center, placebo-controlled
and double-blind randomized study.” Cephalalgia,
16, no. 4,
vol.
pp. 257-263, 1996 14.
Institute of Medicine, Dietary Reference Intake for Calcium, Phos-
phorus, Magnesium, Vitamin D, Press, 15.
Fluoride, National
Academy
Washington DC, 1997
Blaylock RL, Excitotoxins: The Taste That Fe,
16.
and
NM,
Health Press, Sante
1997
Durlach forms
Kills,
et
J
of
“Physiopathology of symptomatic and
al.,
central
nervous
hyperexcitability
deficiency: a current general scheme.”
Magnes
due to
latent
magnesium
Res, vol. 13, no. 4,
pp. 293-302, 2000 17.
Cernak
I
et
al.,
“Characterization of plasma magnesium concentra-
tion and oxidative stress following graded traumatic brain injury in
humans 18.
Memon
J Neurotrauma, ZI
magnesium no.
8,
et al.,
vol. 17, no.
1,
pp. 53-68, 2000
“Predictive value of serum ionized but not total
levels in
head
injuries.”
pp. 671-677, 1995
248
Scand J Clin Lah
Invest, vol. 55,
References
19.
Heath DL, Vink R, “Brain tive of rats.”
free
magnesium concentration
is
predic-
motor outcome following traumatic axonal brain injury
Magnes
in
Res, vol. 12, no. 4, pp. 269-277, 1999
20. Blaylock, ibid. 21.
Marcus JC
et
al.,
“Serum ionized magnesium
headaches.”/ Pediatr, vol. 139, no. 22. Altura
BM,
3,
in
post-traumatic
pp. 459-462, 2001
Altura BT, “Association of alcohol in brain injury,
headaches, and stroke with brain-tissue and serum levels of ionized
magnesium:
review of recent findings and mechanisms of action.”
a
Alcohol, vol. 19, no. 2, pp. 119-130, 1999 23. Altura
BM et ah, “Alcohol-induced spasms of cerebral blood vessels:
relation to cerebrovascular accidents vol. 220, no. 4594, pp.
24.
Zhang A cells
et ah,
and sudden death.”
Science,
331-333, 1983
“Chronic treatment of cultured cerebral vascular smooth
with low concentration of ethanol elevates intracellular calcium and
potentiates prostanoid-induced rises in [Ca2+]i: relation to etiology of
alcohol-induced stroke.” Alcohol, vol. 25. Altura
BM,
14, no. 4, pp.
367-371, 1997
Altura BT, “Association of alcohol in brain injury,
headaches, and stroke with brain-tissue and serum levels of ionized
magnesium:
a
review of recent findings and mechanisms of action.”
Alcohol, vol. 19, no.
2,
pp. 119-130, 1999
26. Ibid. 27. Altura
BM
et ah,
“Extracellular
magnesium
regulates nuclear and
perinuclear free ionized calcium in cerebral vascular cells:
possible relation to alcohol and central nervous system injury.”
Alcohol, vol. 23, no. 28.
Ema rated
smooth muscle
2,
pp. 83-90, 2001
M et ah, “Alcohol-induced vascular damage of brain by administration of magnesium.” Alcohol,
vol.
is
15,
ameliono. 2,
pp. 95-103, 1998 29. Altura
BM,
Altura BT, “Association of alcohol in brain injury,
headaches, and stroke with brain-tissue and serum levels of ionized
magnesium:
a review of recent findings
and mechanisms of action.”
Alcohol, vol. 19, no. 2, pp. 119-130, 1999 30. Li
W
et ah,
“Antioxidants prevent depletion of [Mg2+]i induced by
alcohol in cultured canine cerebral vascular sible relationship to
smooth muscle
cells:
pos-
alcohol-induced stroke.” Brain Res Bull, vol. 55,
no. 4, pp. 475-478, 2001
249
References
31.
Horn
“Magnesium and
B,
vol. 6, pp.
32.
the cardiovascular system.”
109-111, 1987
Schulz-Stubner S
et
al.,
“Magnesium
thesia with propofol, remifentanil
randomized prospective study
from cerebrovascular BT, Altura
and mivacurium:
in 50 patients.”
Yang CY, “Calcium and magnesium
34. Altura
as part of balanced general anaes-
a double-blind,
Eur ]
Anaesthesiol,
723-729, 2001
vol. 18, no. 11, pp.
33.
Magnesium
in drinking
water and risk of death
disease.” Stroke, vol. 18, no. 8, pp. 411-414, 1998
BM, “Withdrawal
of
magnesium causes vasospasm
while elevated magnesium produces relaxation of tone in cerebral ar-
Neurosci Lett, vol. 20, no.
teries.”
—aspects
vessels
findings.”
W
36. Li
low
BM,
BT, Altura
35. Altura
et
al.,
Mg
“Interactions of
vol. 3, nos. 4-6, pp.
magnesium
on
cerebral
in cultured canine cerebral vascular
possible relationship to
cells:
NM,
K
195-211, 1984
smooth
Mg(2 + ) deficiency-induced
Bull, vol. 52, no. 2, pp. 151-154,
Blaylock RL, Excitotoxins: The Taste That Fe,
and
“Antioxidants prevent elevation in [Ca(2+)](i) induced by
vasospasm and stroke.” Brain Res 37.
pp. 323-327, 1980
view of stroke. Review of present status and new
Magnesium,
extracellular
muscle
in
3,
Kills,
2000
Health Press, Sante
1997
38. Ibid. 39. Altura
BT
et
al.,
“Low
levels of
in patients early after stroke lic
free calcium
and spasm
Lett, vol. 230, no.
40.
1,
serum ionized magnesium
which
are
found
result in rapid elevation in cytoso-
in cerebral vascular
muscle
cells.”
Neurosci
pp. 37-40, 1997
Rothman SM, Olney JW, “Glutamate and hypoxic-ischemic brain damage.”
Ann
the pathophysiology of
Neurol, vol. 19, pp. 105-111,
1986 41.
Galland L, Superimmunity for Kids, Bantam Doubleday Dell,
New
York, 1988
CHAPTER 1.
Goldberg B, Heart Disease, Future Medicine Publication, Tiburon,
CA, 2.
5
Sei
1998
M
et al.,
“Nutritional epidemiological study on mineral intake
and mortality from cardiovascular vol. 40, pp.
199-207, 1993
250
disease.
Tokushima.” / Exp Med,
References
3.
Zwillinger L, “Effect of magnesium on the heart.” Klin Wochenschr
;
vol. 14, pp.
1429-1433, 1935
4.
Tom
5.
Singh RB, “Magnesium status and risk of coronary artery disease in rural
Miller, personal
communication, March 2001.
and urban populations with variable magnesium consumption.”
Magues Res, vol. 10, no. 6.
Liao
F,
Folsom AR,
3,
“Is
pp. 205-213, 1997
low magnesium concentration
for coronary heart disease?
(ARIC) 7.
study.”
Ford, Earl
from
S.
The
Am Heart J, vol.
atherosclerosis risk in communities 136, no. 3, pp. 480-490, 1998
“Serum magnesium and ischemic heart
a national
sample of
US
a risk factor
disease: findings
adults.” International Journal of Epi-
demiology, vol. 28, pp. 645-651, 1999 8.
MS et al.,
Seelig
“Magnesium
interrelationships in ischemic heart dis-
American Journal of Clinical Nutrition, Jan. 1974 Bitzur R, Cohen H, Shaish A, Varon D, Shoenfeld
ease: a review.” 9.
Sherer Y,
Y,
Harats D, “Mechanisms of action of the anti-atherogenic effect of
magnesium: lessons from
a
mouse model.” Magnes
Res, vol. 14, no. 3,
pp. 173-179, 2001 10.
1 1
.
GA, Gupta RK, Kostellow AB, Ma GY, Zhang A, Altura BT, Altura BM, “Mg2+ modulates membrane sphingolipid and lipid second messenger levels in vascular smooth muscle cells.” FEBS Lett, Morrill
vol. 440, nos. 1-2, pp.
167-171, 1998
Yang ZW, Gebrewold
A et
al.,
“Mg++-induced endothelial-dependent
relaxation of blood vessels and blood pressure lowering: role of
Am J Physiol Regul Integr Comp Physiol, 12.
vol. 278, pp.
NO.”
R628-639, 2000
Goldberg B, Heart Disease, Future Medicine Publication, Tiburon,
CA, 1998 13.
BT
Altura levels
“Magnesium
et al.,
dietary intake modulates blood lipid
and arherogenesis.” Proc Natl Acad
Sci, vol. 87,
no.
5,
pp.
1
840—
1844, 1990 14.
15.
RB
et al.,
Biol Trace
Elem
Corica F
et
Singh
plasma
lipid
“Does
dietary
magnesium modulate blood
lipids?”
Res, vol. 30, pp. 50-64, 1991
al.,
“Effects of oral
magnesium supplementation on
concentrations in patients with non-insulin-dependent
Magnesium Res, vol. 7, pp. 43-46, 1994 Durlach J, “Commentary on recent epidemiological and clinical vances.” Magnesium Research, vol. 9, no. 2, pp. 139-141, 1996 diabetes mellitus.”
16.
251
ad-
References
17.
Fallon
M et
Gao
Enig M, Nourishing Traditions, Locomotion Press,
MD,
more, 18.
S,
1995
al.,
“Cardiovascular risk factors emerging in Chinese popu-
undergoing urbanization.” Hypertens Res,
lations
Balti-
vol. 22, pp.
209-215,
1999 19.
Marier JR, “Magnesium content of the food supply
day world.” Magnesium 20. Liu
L
modern-
1986
vol. 5, pp. 1-8,
“Comparative studies of diet-related factors and blood
et al.,
among Chinese and
pressure
in the
Japanese: results from the China-Japan
Cooperative Research of the
WHO-CARDIAC
Study.
Cardio-
vascular disease and alimentary comparison.” Hypertens Res, vol. 23,
pp. 413-420, 2000 21.
McCully KS, “Homocysteine,
folate,
vitamin B^, and cardiovascular
JA MA, vol. 279, no. 5, pp. 392-393, 1998 McCully KS, “Vascular pathology of homocysteinemia:
disease.” 22.
for the pathogenesis of arteriosclerosis.”
Am J Pathol,
implications
vol. 56, no. 1,
pp. 111-128, 1969 23.
Eikelboom gram.”
24.
JW
Ann
et
al.,
“Preventive cardiology and therapeutics pro-
Intern Med, vol. 131, no.
Boushey CJ
et
al.,
“A
5,
pp. 363-375, 1999
quantitative assessment of plasma
homo-
cysteine as a risk factor for vascular disease. Probable benefits of in-
creasing folic acid intakes.”
JAMA,
vol. 274, no. 13, pp.
1049-1057,
1995 25. Confalonieri
tectable
M
et
al.,
“Heterozygosity for homocysteinuria:
and reversible risk factor for pulmonary thromboembolism.”
Monaldi Arch Chest Disease, 26. Altura B, Altura B,
Alumni Today,
W
et
al.,
1995
vol. 50, no. 2, pp. 114-115,
“Magnesium: the forgotten mineral
cular health and disease.”
27. Li
a de-
A Gem
Lecture
at
in cardiovas-
SUNY
Downstate.
pp. 11-22, spring 2001
“Extracellular
magnesium
regulates effects of vitamin B^,
Bj 2 and folate on homocysteinemia-induced depletion of intracellular free cells:
magnesium ions
in canine cerebral vascular
possible relationship to [Ca2 + ]i, atherogenesis and stroke.”
Neurosci Lett, vol. 274, no. 28.
smooth muscle
Shamsuddin
AM,
2,
“Inositol
pp. 83-86, 1999
phosphates
have
novel
anti-cancer
function.” Journal of Nutrition, vol. 125 (suppl.), pp. 725S-732S,
Review 1995
252
References
29.
KG
Rowley
“Improvements
et al.,
in circulating cholesterol, anti-
oxidants, and homocysteine after dietary intervention in an
Aboriginal community.”
tralian
Am
J Clin Nutr,
vol.
Aus-
74, no. 4,
pp. 442-448, 2001 30. Tice
JA
et
“Cost-effectiveness of vitamin therapy to lower plasma
al.,
homocysteine
prevention of coronary heart disease:
levels for the
and beyond.”
effect of grain fortification
JAMA,
vol. 286, no. 8,
pp. 936-943,2001 31. Vollset
SE
et
“Plasma
al.,
total
homocysteine and cardiovascular and
noncardiovascular mortality: the Hordaland Homocysteine Study.”
Am J Clin Nutr, vol.
74, no.
1,
pp. 130-136, 2001
Desk Reference Altura BM et al., “Hypomagnesemia and vasoconstriction: possible
32. Physicians' 33.
relationship to etiology of sudden death ischemic heart disease and
hypertensive vascular diseases.” Artery, vol.
9,
no.
3,
pp. 212-231,
1981 34.
Mindell E, Prescription Alternatives, Keats Publishing, Los Angeles, 1999
35. Millane T,
Camm A, Medical Sciences Bulletin, May
mation Associates, 36.
K
Kisters
et
BM,
Magnesium
Altura
sion: correlation
1994
“Hypomagnesaemia, borderline hypertension and
al.,
hyperlipidaemia.” 37. Altura
Pharmaceutical Infor-
BT
et
al.,
Bull, vol. 21, pp. 31-34,
1999
“Magnesium deficiency and hyperten-
between magnesium-deficient
diets
and microcircula-
tory changes in situ.” Science, vol. 223, no. 4642, pp. 1315-1317, 1984 38.
Resnick the
LM et
al.,
“Factors affecting blood pressure responses to
Vanguard study.”
Am J
Hypertens, vol. 13, no.
9,
diet:
pp. 956-965,
2000 39.
Altura
BM,
Altura BT,
“
Interactions of
aspects in view of hypertension. findings.” 40. Pierce JB,
Magnesium,
Mg and K on blood vessels
Review of present
vol. 3, nos. 4-6, pp.
and new
175-194, 1984
Heart Healthy Magnesium: Your Nutritional Key
diovascular Wellness, Avery Publishing Group, 41. Shechter
status
M et
al.,
New York,
to
Car-
1994
“Beneficial antithrombotic effects of the association
of pharmacological oral heart disease patients.”
magnesium therapy with
Magnes Research,
2000
253
aspirin in coronary
vol. 13, no. 4, pp.
275-284,
References
42. Zwillinger L, “Effect of
43.
44.
magnesium on
vol. 14, pp.
1429-1433, 1935
Boyd LJ
et
al.,
Med Sci,
vol. 206, pp.
KK et
Teo
“Magnesium
paroxysmal tachycardia.”
sulfate in
magnesium
myocardial infarction: Overview of randomized
in suspected acute
trials.” Brit
Med J,
1499-1503, 1991
vol. 303, pp.
45.
Am
43-48, 1943
“Effects of intravenous
al.,
the heart.” Klin Wochenschr,
Teo KK, Yusuf
S,
“Role of magnesium in reducing mortality
A
myocardial infarction.
review of the evidence.” Drugs
in acute vol. 46,
pp. 347-359, 1993 46.
Woods KL
et
al.,
“Intravenous magnesium sulfate in suspected acute
myocardial infarction: results of the second Leicester Intravenous
Magnesium Intervention
Trial
(LIMIT-2).” Lancet,
vol. 339, pp.
1
553—
1558, 1992. 47.
Woods KL,
Fletcher
nesium sulphate
“Long-term outcome
S,
in suspected acute
Leicester Intravenous
after intravenous
mag-
myocardial infarction: the second
Magnesium Intervention
(LIMIT-2),”
Trial
Lancet, vol. 343, pp. 816-819, 1994 48.
Ravn HB, “Pharmacological thrombosis no.
49.
—mechanisms
of action?”
of
magnesium on
Magnes Research,
arterial
vol.
12,
pp. 191-199, 1999
3,
Young
IS et
al.,
“Magnesium
Pharmacol, vol. 32, no. 50.
effects
Lewis
R
et al.,
6,
status
toxicity.”
Br ] Clin
pp. 717-721, 1991
“Magnesium
deficiency
minant of ventricular ectopy atrial fibrillation.”
and digoxin
may
be an important deter-
in digitalised patients
Br ] Clin Pharmacol,
with chronic
vol. 31, no. 2, pp.
200-203,
1991 51. ISIS-4
(Fourth International Study of Infarct Survival) Collaborative
Group, topril,
“ ISIS-4: a
randomised
oral mononitrate,
factorial trial assessing early oral cap-
and intravenous magnesium sulphate
in
58,050 patients with suspected acute myocardial infarction.” Lancet, vol. 345, pp.
52. Seelig
sium
669-685, 1995
MS, “Cardiovascular
deficit in
ment of
Am
M
by magne-
consequences of magnesium deficiency on the enhance-
stress reactions; preventive
review.”/ 53. Shechter
reactions to stress intensified
Coll Nutr, vol. 13, no.
et al.,
and therapeutic implications: 5,
pp. 429-446, 1994
“Magnesium therapy
254
a
in acute
myocardial infarc-
References
tion
when
patients are not cardiologists for thrombolytic therapy.”
AM J Cardiology, vol. 75, pp. 321-323,
1995.
Heart Healthy Magnesium: Your Nutritional Key
54. Pierce JB,
diovascular Wellness, Avery Publishing Group,
“Magnesium and
55. Iseri LT,
nos. 3-4, pp.
1 1
“Magnesium therapy of Magnesium,
critical-care medicine.”
et al., “ Antiarrhythmic
F
vol. 5, no. 3, pp.
vol. 8, pp.
299-306, 1989
short-term protective magnesium
60.
Am
Coll Nutr,
492-499, 1990
Heart Healthy Magnesium: Your Nutritional Key
diovascular Wellness, Avery Publishing Group, 59.
vol. 5,
cardiac arrhythmias in
treatment in ischemic dilated cardiomyopathy.” J
58. Pierce JB,
1994
Magnesium,
cardiac arrhythmias.”
Car-
1-126, 1986
56. Iseri LT, Allen BJ,
57. Perticone
New York,
to
Boyd LJ
et al.,
Med Sci,
vol. 206, pp.
“Magnesium
sulfate in
New York,
to
Car-
1994
paroxysmal tachycardia.”
Am J
43-48, 1943
Parikka HJ, Toivonen LK, “Acute effects of intravenous magnesium
on
ventricular refractoriness and
tion in humans.”
monophasic action potential dura-
Scand Cardiovasc
J, vol. 33,
no.
5,
pp. 300-305,
1999 61. Thiele R,
Protze
F,
Winnefeld K, Pfeifer R, Pleissner
magnesium on
“Effect of intravenous
J,
Gassel
M,
ventricular tachyarrhythmias
associated with acute myocardial infarction.”
Magnes
Res, vol. 13,
no. 2, pp. 111-112, 2000 62.
Ceremuzynski L
et
“Hypomagnesaemia
al.,
with ven-
in heart failure
magnesium supplementa-
tricular arrhythmias. Beneficial effects of
tion.”/ Intern Med, vol. 247, pp. 78-86, 2000 63.
Dyckner T
et al.,
“Magnesium
deficiency in congestive heart failure.”
Acta Pharmacol Toxicol Copenh, 64.
65.
England
MR
et
al.,
vol. 54, suppl.
1,
pp. 119-123, 1984
“Magnesium administration and dysrhythmias
after cardiac
surgeryT JAMA, vol. 268, pp. 2395-2402, 1992
Caspi J
“Effects of
et
al.,
magnesium on myocardial function
nary artery bypass grafting.”
Ann Thorac
after coro-
Surg, vol. 59, pp. 942-947,
1995 66.
Toraman
F,
Karabulut
EH, Alhan HC, Dagdelen
S,
Tarcan
nesium infusion dramatically decreases the incidence of tion after coronary artery bypass grafting.”
no.
4,
pp. 1256-1261, 2001
255
S,
“Mag-
atrial fibrilla-
Ann Thorac Surg,
vol. 72,
References
v MS, “Review and hypothesis: might patients with the chronic fatigue syndrome have latent tetany of magnesium deficiency.” J Chron Fatigue Syndr, vol. 4, pp. 77-108, 1998 Lichodziejewsa B et al., “Clinical symptoms of mitral valve prolapse are related to hypomagnesemia and attenuated by magnesium sup-
67. Seelig
68.
plementation.”
CHAPTER 1.
vol. 79, pp.
768-772, 1997
6
Singh RB, “Association of low plasma concentrations of antioxidant vitamins,
men.” 2.
Amer J Cardiology
Ma J
magnesium and
zinc with high
Magues Res, vol. 11, no. et al.,
1,
body
fat
per cent in Indian
pp. 3-10, 1998
“Associations of serum and dietary magnesium with car-
diovascular disease, hypertension, diabetes, insulin, and carotid arterial wall thickness; the
ARIC study, Artherosclerosis Risk in Communities
Study.” / Clin Epidemiol, vol. 48, pp. 927-940, 1995 3.
Humphries
S et
“Low
al.,
dietary
magnesium
is
associated with
insulin resistance in a sample of young, non-diabetic Black
Am J Hypertens, vol. 12, no. 8, pt. pp. 747-756, 1999 Alzaid AA et “Effects of insulin on plasma magnesium in noninsulin-
cans.” 4.
Ameri-
1,
al.,
dependent diabetes mellitus: evidence for insulin resistance.” / Clin Endocrinol Metab, vol. 80, no. 4, pp. 1376-1381, 1995 5.
Barbagallo
M
et
hyperglycemia pt. 2, 6.
al.,
in
“Altered cellular magnesium responsiveness to
hypertensive subjects.” Hypertension, vol. 38, no. 3
pp. 612-615, 2001
Dominguez LJ insulin-like
“Magnesium responsiveness to insulin and growth factor I in erythrocytes from normotensive et al.,
and hypertensive subjects.” / Clin Endocrinol Metab,
vol. 83, no. 12,
pp. 4402-4407, 1998 7.
Resnick
LM,
and diabetes:
obesity,
(4 suppl.), pp. 8.
“Cellular ions in hypertension,
unifying theme.” /
in Finland:
The Lancet, Dec. Resnick
LM,
lar disease,
Am
resistance,
Soc Nephrol, vol. 3
578-585, 1992
Karppanen H, Neuvonen nesium
9.
a
insulin
PJ,
“Ischaemic heart-disease and
soil
mag-
water hardness and magnesium in heart muscle.”
15,
1973
“Ionic basis of hypertension, insulin resistance, vascu-
and related disorders. The mechanism of syndrome X.”
Am J Hypertens, vol. 6, no. 5, pt.
1,
256
pp. 413-417, 1993
References
10.
LM, “The
Resnick
clinical conditions.” 11.
LM
Resnick
cellular ionic basis of
Prog Cardiovasc Dis,
hypertension and
vol. 42, pp. 1-22,
“Hypertension and peripheral insulin
et al.,
1999
resistance.
Possible mediating role of intracellular free magnesium.”
Hypertens, vol. 12.
G
Paolisso
et
no.
3,
5, pt. 1,
“Low
al.,
magnesium accumulation tricular
Am
J
pp. 373-379, 1990
and insulin-mediated
fasting in
allied
intracellular
hypertensive patients with
left
ven-
hypertrophy; role of insulin resistance.” Hypertens, vol.
9,
pp. 199-203, 1995 13.
Nadler JL et al., “Magnesium deficiency produces insulin resistance and increased thromboxane synthesis.” Hypertension, vol. 21, no. 6, pt. 2,
14.
pp. 1024-1029, 1993
M et
Bardicef
“Extracellular and intracellular
al.,
tion in pregnancy and gestational diabetes.” vol. 172, no. 3, pp. 15.
Resnick
LM
et
al.,
magnesium deple-
Am ]
Obstet Gynecol,
1009-1013, 1995 “Intracellular
and extracellular magnesium deple-
tion in type 2 (non-insulin-dependent) diabetes mellitus.” Diabetologia, vol. 36, no. 8, pp.
16.
Kao
WH
et
al.,
767-770, 1993
“Serum and dietary magnesium and the
risk for
type 2 diabetes mellitus: the Atherosclerosis Risk in Communities Study.” Arch Intern Med, vol. 159, no. 18, pp. 2151-2159, 1999 17.
Lima
M de L, “The effect of magnesium supplementation in increas-
ing doses
no. 18.
5,
on the control of type 2
diabetes.” Diabetes Care, vol. 83,
pp. 682-686, 1998
Paolisso G, Barbagallo
M, “Hypertension,
insulin resistance: the role of intracellular
Merz
CN et
al.,
in patients
platelet-
with coronary artery disease.”
Am
] Cardiol, vol. 84, pp. 152-156, 1999 Lima de L, “The effect of magnesium supplementation in increasing doses on the control of type 2 diabetes.” Diabetes Care, vol. 83,
M
no. 21.
Am ] Hyper-
“Oral magnesium supplementation inhibits
dependent thrombosis
20.
magnesium.”
346-355, 1997
tens, vol. 10, no. 3, pp.
19.
diabetes mellitus, and
5,
pp. 682-686, 1998
Engelen W, Bouten A,
sium
levels in
signs of
type
1
De Leeuw
I,
De Block
C, “Are low magne-
diabetes associated with electromyographical
polyneuropathy?” Magnes Res,
2000
257
vol. 13, no. 3, pp. 197-203,
References
22.
MS
Djurhuus
bolic control
type
“Effect of moderate
et al.,
on magnesium and
in
meta-
lipid concentrations in patients
with
diabetes.” Diabetes Care, vol. 22, no. 4, pp. 546-554, 1999
1
“The amazing
23. Squires S,
statistics
Ludwig DS
et al.,
and dangers of soda pop.” Wash-
HE 10.
ington Post, February 27, 2001, p. 24.
improvement
“Relation between consumption of sugar-sweetened
drinks and childhood obesity: a prospective, observational analysis.” Lancet, vol. 357, no. 9255, pp. 505-508, 2001 25. Bernstein J et
al.,
“Depression of lymphocyte transformation follow-
ing oral glucose ingestion.” 26.
Sanchez sis.”
A
et al.,
Am J Clin Nutr, vol. 30, p. 613,
“Role of sugars in human neutrophilic phagocyto-
Am J Clin Nutr, vol. 26, no. E
27. Kijak
et
11, pp.
1180-1184, 1973
“Relationship of blood sugar level and leukocytic
al.,
phagocytosis.” S Calif State Dent Assoc J, vol. 32, no. 28.
Lima
29.
1964
on the control of type
2 diabetes.” Diabetes Care, vol. 83,
pp. 682-686, 1998
5,
Yang
9,
M de L, “The effect of magnesium supplementation in increas-
ing doses no.
1977
CY
et
“Magnesium in drinking water and mellitus.” Magnes Res, vol. 12, no.
al.,
from diabetes
the risk of death 2,
pp. 131-137,
1999 30.
31.
HX
Zhao
et
al.,
“Drinking water composition and childhood-onset
type
1
Med,
vol. 18, no. 9, pp.
diabetes mellitus in
Devon and Cornwall, England.” Diabet
709-717, 2001
Howard JMH, “Magnesium ease.”/ Nutritional Med, vol.
32.
CHAPTER
An
7
Sherwood
RA
June 1995, et
al.,
p.
26
“Magnesium and
the premenstrual syndrome.”
Clin. Biochem., vol. 23, no. 6, pp. 667-670, 1986
Posaci et
al.,
“Plasma copper, zinc and magnesium
with premenstrual tension syndrome.” cology Scand, vol. 73, no. 4.
Ignored Epidemic. Sunshine
Werbach M, “Premenstrual syndrome: magnesium.” Townsend Let-
Ann. 3.
39, 1990
West Palm Beach, FL, 2001
ter for Doctors, 2.
1, p.
Roberts HJ, Aspartame Disease: Sentinel Press,
1.
deficiency in peripheral vascular dis-
Facchinetti
F
et al.,
6,
ACTA
levels in patients
Obstetrics
and Gyne-
pp. 452-455, 1994
“Oral magnesium successfully
258
relieves
premen-
References
mood
strual
changes.” Obstetrics
and Gynecology (USA),
vol. 78,
no. 2, pp. 177-181, 1991 5.
Somer
New York
Collins, 6.
The Essential Guide
E,
cle in
Li
W
O
et
al.,
et al.,
levels
throughout the menstrual cy-
Fertil Steril, vol. 69, no. 5, pp. 58-62, 1998
“Sex steroid hormones exert biphasic effects on cytosolic
magnesium ions
in cerebral vascular
smooth muscle
cells:
lationships to migraine frequency in premenstrual
9.
stroke incidence.” Brain Res Bull, vol. 54, no.
1,
Marz R, Medical Nutrition from Marz, 2nd
ed.
land, 10.
OR,
Benassi
Prima Pub-
“Sex steroid hormones modulate serum
magnesium and calcium
women.”
ed,
CA, 1998
Muneyvirci-Delale ionized
8.
1995
Murray M, Encyclopedia of Natural Medicine, 2nd lishing, Rocklin,
7.
Vitamins and Minerals, Harper-
to
possible re-
syndromes and
pp. 83-89, 2001
Omni
Press, Port-
1997
L
et
of
“Effectiveness
al.,
magnesium
pidolate
the
in
prophylactic treatment of primary dysmenorrhea.” Clin Exp Obstet
Gynecol, vol. 19, no. 1 1
.
Fontana- Klaiber H,
3,
pp. 176-179, 1992
Hogg B,
“Therapeutic effects of magnesium in dys-
menorrhea.” Schweiz Rundsch
Med
Prax, vol. 79, no. 16, pp. 491-494,
1990 12.
Seifert
B
et
“Magnesium
al.,
—
a
new
therapeutic alternative in primary
dysmenorrhea.” Zentralbl Gynakol,
vol.
Ill, no. 11, pp. 755-760,
1989 13.
Goldberg B, Alternative Medicine Guide: Women's Eiealth Future Medicine Publication, Tiburon,
14.
1,
1998
Franz KB, “Magnesium intake during pregnancy.” Magnesium, vol. 6, pp. 18-27,
15.
CA,
Series
1987
Muneyvirci-Delale
O et
al.,
“Divalent cations in
women with PCOS:
implications for cardiovascular disease.” Gynecol Endocrinol, vol. 15, no. 16.
3,
pp. 198-201, 2001
Conradt A, Weidinger
AH, “The
central position of
magnesium
in
—
management of fetal hypotrophy a contribution to the pathomechanism of utero-placental insufficiency, prematurity and poor in-
the
trauterine fetal vol. 4, pp. 17.
growth
as well as
pre-eclampsia.”
Magnesium
Bull,
103-124, 1982
Handwerker
SM
et
al.,
“Ionized
259
serum magnesium
levels
in
References
umbilical cord blood of normal pregnant
women
at delivery: rela-
tionship to calcium, demographics, and birthweight.” vol. 10, no. 5, pp. 18.
392-397, 1993
Handwerker SM, Altura BT, Altura BM, “Serum ionized magnesium and other electrolytes
J Am Coll Nutr, 19.
Am J Perinatol,
Lazard
EM, “A
sium sulphate
in the antenatal period of
vol. 15, no. 1, pp.
human
pregnancy.”
36-43, 1996
preliminary report on the intravenous use of magne-
in puerperal eclampsia.”
Am
] Obst Gynec,
vol. 9,
pp. 178-188, 1925 20. Seelig
MS, Magnesium Deficiency
in the Pathogenesis
of Disease. Early
Roots of Cardiovascular, Skeletal, and Renal Abnormalities, Plenum,
21.
New York, 1980 Almonte RA et al., to fetal
“Gestational magnesium deficiency
outcome.” Biol Neonate,
vol. 76, no.
1,
is
deleterious
pp. 26-32, 1999
MS, “Toxemias of pregnancy, postpartum cardiomyopathy and SIDS in consequences of magnesium deficiency on the enhancement of stress reactions; preventive and therapeutic implications: a
22. Seelig
review.” J 23. Seelig
New York, pp.
MS, “Magnesium
cent mother.” J 25.
5,
pp. 429-446, 1994
chromium.” In Clinical Disorders
Dekker,
24. Seelig
Coll Nutr, vol. 13, no.
MS, “Prenatal and neonatal mineral
zinc and cel
Am
Am
deficiencies:
magnesium,
in Pediatric Nutrition,
Mar-
167-196, 1982
in
pregnancy: special needs for the adoles-
Coll Nutr, vol. 10,
p. 566,
1991
Caddell JL, “Magnesium deficiency promotes muscle weakness, contributing to the risk of
sudden infant death (SIDS)
in infants sleeping
prone.” Magnes Res, vol. 14, nos. 1-2, pp. 39-50, 2001 26.
Caddell JL,
“A
triple-risk
model for the sudden
infant death syn-
drome (SIDS) and the apparent life-threatening episode (ALTE): stressed magnesium deficient weanling rat.” Magnes Res, vol. no. 27.
28.
29.
3,
the 14,
pp. 227-238, 2001
“Magnesium and thermoregulation. I. Newborn and infant. Is sudden infant death syndrome a magnesium-dependent disease of the transition from chemical to physical thermoregulation.” Magnes Res, vol. 4, pp. 137-152, 1991 Nelson KB et al., “Can magnesium sulfate reduce the risk of cerebral palsy in very low birth weight infants ? ” Pediatrics, vol. 95, no. 2, 1 995 Schendel D et al., “Prenatal magnesium sulfate exposure and the risk Durlach
J et
al.,
260
References
for cerebral palsy or mental retardation
among very low
birth-weight
children aged 3-5 years ” JAMA, vol. 276, pp. 1805-1810, 1996 30.
Dedhia HV, Banks DE, “Pulmonary response magnesium.” Environ Health
to hyperoxia: effects of
Perspect, vol. 102, suppl. 10, pp. 101-105,
1994 31.
Oorschot DE, “Cerebral palsy and experimental hypoxia-induced perinatal brain injury:
magnesium protective?” Magnes
is
Res, vol. 13,
no. 4, pp. 265-273, 2000 32.
Bara M, Guiet-Bara A, “Magnesium regulation of Ca24- channels in
smooth muscle and endothelial tal
Magnes Research,
vessels.”
CHAPTER 8 1. Brown S,
of
cells
human
allantochorial placen-
vol. 14, nos. 1-2, pp. 11-18,
Better Bones, Better Body, Keats Publishing,
2001
New
Canaan,
CT, 1996 2.
Thomas AJ
“Ca,
et al.,
Mg
and P
intake, metabolic balance studies vol. 62, pp. 3.
4.
status.” Br. J. Nutr,
in the elderly.”
Br J Biomed
Sci, vol. 51,
pp. 228-240, 1994
The National sis,
5.
3,
and biochemical
211-219, 1989
Bunker VW, “Osteoporosis no.
status of elderly inpatients: dietary
Institutes of
Health Osteoporosis Prevention, Diagno-
and Therapy Consensus Statement, Mar. 2000
Rude RK, “Magnesium deficiency-induced osteoporosis in the rat: uncoupling of bone formation and bone resorption.” Magnes Research, vol. 12, no. 4, pp. 257-267, 1999
10.
6.
Rude Miner
7.
RK et
al.,
“Magnesium
deficiency induces bone loss in the rat.”
Electrolyte Metab, vol. 24, no.
Brodowski stages of
J,
5,
pp. 314-320, 1998
“Levels of ionized magnesium in
women
with various
postmenopausal osteoporosis progression evaluated on the
basis of densitometric examinations.” Przegl Lek, vol. 57, no.
12,
pp. 714-716, 2000 8.
Sojka JE, Weaver sis.”
9.
CM, “Magnesium
supplementation and osteoporo-
Nutrition Reviews, vol. 53, p. 71, 1995.
Goldberg B, Alternative Medicine Guide: Women's Health Future Medicine Publishing, Tiburon,
CA,
Series
2,
1998
Dreosti IE, “Magnesium status and health.” Nutrition Reviews, vol. 53, no. 9, pp.
523-527, 1995
261
References
11.
Abraham GE, Grewal HA, nesium instead of calcium:
bone
in
postmenopausal
“Total dietary program emphasizing mag-
effect
on the mineral density of calcaneous
women on hormonal
Reproductive Medicine, vol. 35, no. 12.
5,
therapy.” Journal of
pp. 503-507, 1990
MS, “Increased magnesium need with use of combined estrogen and calcium for osteoporosis.” Magnesium Res, vol. 3, pp. 197-215, Seelig
1990 13.
Goldberg B, Alternative Medicine Guide: Women's Health Future Medicine Publishing, Tiburon,
14.
Brown
S,
Series 2,
CA, 1998
Better Bones, Better Body, Keats Publishing,
New Canaan,
CT, 1996 15.
Tucker
KL et al.,
“Potassium, magnesium, and
takes are associated with greater
and women.” 16.
Hall
WD
fruit
and vegetable
bone mineral density
in elderly
Am J Clin Nutr, vol. 69, no. 4, pp. 727-736,
et ah,
Am J Med Sci, vol. 322, no.
men
1999
“Risk factors for kidney stones in older
the southern United States.”
in-
1,
women
in
pp. 12-18,
2001 17.
Milne DB, Nielsen FH, “The interaction between dietary fructose
and magnesium adversely
J Am Coll Nutr, 18.
affects
vol. 19, no.
1,
macromineral homeostasis
Institute of Medicine. Dietary Reference Intake for Calcium, Phos-
Press,
20.
men.”
pp. 31-37, 2000
phorus, Magnesium, Vitamin D,
19.
in
and
Fluoride, National
Academy
Washington DC, 1997
“Too much soda may take some fizz out of the bones.” Proc ND Acad Sci, vol. 51, p. 212, 1998 Bunce GE et ah, “Distribution of calcium and magnesium in rat kidMilne D, Nielsen
F,
ney homogenate fractions accompanying magnesium deficiency duced nephrocalcinosis.” Exp Mol Pathol,
in-
vol. 21, no. 1, pp. 16-28,
1974 21.
G et ah, “Effects of magnesium disease.” J Am Coll Nutr, vol. 1, no. 2, 1982 Johansson
22. Prien
in renal stone
EL, “Magnesium oxide-pyridoxine therapy for recurring
cium oxalate urinary 23.
hydroxide
Johannson
G
et ah,
calculi.”
/ Urology,
“Biochemical and
vol. 112, pp.
cal-
509-551, 1974
clinical effects of
prophylactic
treatment of renal calcium stones with magnesium hydroxide.”
J
Urol, vol. 124, pp. 770-774, 1980
24. Driessens
FC, Verbeeck RM, “On the prevention and treatment of
262
cal-
References
cification disorders of old age.”
Med
Hypotheses
vol. 3, pp. 131-137,
1988 25.
Labeeuw
M
et al.,
“Role of magnesium
treatment of calcium renal
lithiasis.”
in the
Presse
physiopathology and
Med,
vol.
16,
no.
1,
pp. 25-27, 1987 26.
Jeppesen BB, “Greenland,
a soft- water area
ischemic heart death.” Magnesium, vol.
CHAPTER 1
.
6,
with
a
low incidence of
no. 6, pp. 307-313, 1987
9
Goldstein JA,
Chronic Fatigue Syndromes: The Limbic Hypothe-
ed.,
Haworth Press, New York, 1993 Seelig MS, “Review and hypothesis: might patients with the chronic fatigue syndrome have latent tetany of magnesium deficiency.” ] Chron Fatigue Syndr, vol. 4, pp. 77-108, 1998 Papadopol V, Tuchendria E, Palamaru I, “Magnesium and some psychological features in two groups of pupils (magnesium and psychic features).” Magnes Research, vol. 14, nos. 1-2, pp. 27-32, 2001 sis,
2.
3.
4.
Durlach
V
et
al.,
“Neurotic, neuromuscular and autonomic nervous
form of magnesium imbalance.” Magnes 5.
Cox IM, “Red blood The Lancet,
6.
cell
Res, vol. 10, pp. 169-195, 1997
magnesium and chronic
26 Doctors Show You
Clinically ing,
Ibid.
8.
Seelig
How
&
Environmental
They Reverse These Conditions with
MS,
CA,
1998
“Athletic stress, performance and
magnesium
in conse-
quences of magnesium deficiency on the enhancement of reactions; preventive
9.
and therapeutic implications:
CollNutr, vol.
13, no. 5, pp.
Abraham GE,
Flechas JD,
for the
Ill-
Proven Alternative Therapies, Future Medicine Publish-
Tiburon,
7.
syndrome.”
vol. 337, pp. 757-760, 1991
Goldberg B, Chronic Fatigue, Fibromyalgia ness:
fatigue
a
stress
review” ]
Am
429-446, 1994
“Management of fibromyalgia: rationale use of magnesium and malic acid.” P ] Nutr Med, vol. 3,
pp. 49-59, 1992
CHAPTER 10 1. “Nowhere supply.”
to hide: persistent toxic chemicals
Pesticide
in
the U.S. food
Action Network North America
263
(PANNA)
References
and Commonweal. 2000. www.panna.org, (415) 981-1771; commonweal.org. 2.
3.
Control and Prevention press conference,
Centers for Disease
GA, March
Atlanta,
“GAO
finds that
www.
21, 2001
USDA, EPA
cide use.” U.S. General
have neglected pledge to cut pesti-
Accounting Office, U.S. Newswire, Septem-
ber 27, 2001, available at www.gao.gov 4.
R
Kreutzer
“Prevalence of people reporting sensitivities to
et al.,
chemicals in a population-based survey.”
Am ] Epidemiol
vol. 150,
no. l,pp. 1-12, 1999 5.
“Everyday carcinogens: stopping cancer before
it
starts.”
Workshop
on Primary Cancer Prevention. McMaster University, Hamilton, Ontario, Canada. March 26-27, 1999 6.
Deborah Baker, personal communication. Dr. Baker mercury research at www.y2khealthanddetox.com
7.
Goering
PL
et
al.,
dental amalgams.”
shares
her
“Toxicity assessment of mercury vapor from
Fundam Appl
Toxicol, vol. 19, no. 3, pp. 319-329,
1992 8.
Halbach view.”
9.
S,
“Amalgam tooth
Hum Exp
Lorscheider
FL
fillings
Toxicol, vol. 13, no. 7, pp.
et
al.,
no.
10.
7,
tooth
fillings:
paradigm.”
FASEB
‘silver’
a traditional dental
pp. 504-508, 1995
Arenholt-Bindslev D, Larsen in
496-501, 1994
“Mercury exposure from
emerging evidence questions J, vol. 9,
and mans mercury burden. Re-
waste water from dental
AH, “Mercury
clinics.”
levels
Water Air
and discharge
Soil Pollut, vol. 86,
nos. 1-4, pp. 93-99, 1996 11.
Drasch
G
et
al.,
of Leipzig and
mercury
—
a
“Comparison of
Munich with
study of
vol. 56, no. 5, pp. 12.
the
human organ
samples.” Gesundheitswesen,
263-267, 1994
Liu XY, Jin TY, Nordberg GF, “Increased urinary calcium and mag-
nesium excretion
in rats injected
Toxicol, vol. 68, no. 4, pp. 13.
body burden of the population heavy metals cadmium, lead and
the
Durlach chapter
J, 1,
with mercuric chloride.” Pharmacol
254-259, 1991
“Diverse applications of magnesium therapy. Part section B.
Handbook
five,
of metal-ligand interactions in bio-
logical fluids,” in Bioinorganic Medicine, vol. 2,
York, 1995
264
Marcel Dekker,
New
References
14.
T
Kedryna
“Effect of environmental fluorides
et al.,
chemical processes in humans.” Folia
Med
on key bio-
Cracov, vol. 34, no. 1-4,
pp. 49-57, 1993 15.
Semczuk M, Semczuk-Sikora A, “New
Hg
tion (Cd, Pb, and
Med Sci Monit,
Review.” 16.
Ibid.
17.
Durlach
in particular)
J et
al.,
“Magnesium:
18.
Magnesium Res
D et
Soldatovic
al.,
toxic metal intoxica-
Mg status
vol. 7, no. 2, pp.
cadmium. Ultrastructure cell.”
and
on
data
during pregnancy.
332-340, 2001
a competitive inhibitor of lead
studies of the
vol. 3, pp. 31-36,
human
and
amniotic epithelial
1990
“Contribution to interaction between magnesium
and toxic metals: the
effect of
magnesium metabolism
prolonged cadmium intoxication on
rabbits.”
in
Magnes
Res, vol.
11,
no. 4,
pp. 283-288, 1998 19.
VG, “Influence Altura BM, Durlach Allen
of J,
aluminum on magnesium metabolism.” Seelig
MS,
eds.,
Magnesium
in
and Medicine. Krager, Basel, pp. 50-66, 1987 Rogers S, The El Syndrome: A Rxfor Environmental Illness.
In:
Cellular
Processes 20.
SK
Publishing, Sarasota, FL, 1995.
21. Seelig
M, “Consequences
ment of
stress
23.
of
magnesium deficiency on
reactions; preventive
the enhance-
and therapeutic implications
] Am CollNutr vol. 13, no. 5, pp. 429-446, 1994 Physicians'' Desk Reference Gurkan F et al., “Intravenous magnesium sulphate in the management of moderate to severe acute asthmatic children nonresponding to conventional therapy.” Eur J Emerg Medicine, vol. 6, no. 3, (a review).”
22.
Rev. ed.
;
pp. 201-205, 1999 24. Ciarallo
F
et
al.,
“Intravenous magnesium therapy for moderate to
severe pediatric asthma: results of a randomized, placebo-controlled
J Pediatr, Dominguez FJ
trial .”
25.
vol. 129, pp. 809-814, et
al.,
1996
“Bronchial reactivity and intracellular mag-
nesium: a possible mechanism for the bronchodilating effects of
magnesium
in asthma.” Clin Sci (Colch), vol. 95, no. 2, pp. 137-142,
1998 26. Britton J,
“Dietary magnesium, lung function, wheezing and airway
hyperreactivity in a
random population sample.”
pp. 357-362, 1994
265
Lancet, vol. 344,
References
CHAPTER 11 1.
M
Barbagallo
et
al.,
“Cellular ionic alterations with age: relation to
hypertension and diabetes
”
J Am Geriatr Soc,
vol. 48, no. 9, pp. llll-
2000
ll 16, 2.
.
M, “Diabetes
Barbagallo
mellitus, hypertension
and ageing: the ionic
hypothesis of ageing and cardiovascular-metabolic diseases.” Diabetes Metab, vol. 23, no. 4, pp. 281-294, 1997 3.
Hartwig A, “Role of magnesium
in
genomic
stability.”
Mutat Re-
search vol. 18, no. 475 (1-2), pp. 113-121, 2001 4.
M
Worwag
in nursing
et
al.,
home
“Prevalence of magnesium and zinc deficiencies
residents in
Magues Res, vol.
Germany.”
12, no. 3,
pp. 181-189, 1999 5.
G
Paolisso
et
al.,
“Mean
arterial
blood pressure and serum
of the molar ratio of insulin-like growth factor- 1 to
its
levels
binding
protein-3 in centenarians.”/ Hypertens, vol. 17, pp. 67-73, 1999 6.
Li
W
low
et
al.,
“Antioxidants prevent elevation in [Ca(2+)](i) induced by
magnesium
extracellular
muscle
in cultured canine cerebral vascular
possible relationship to
cells:
vasospasm and stroke.” Brain Res 7.
smooth
Mg(2 + ) deficiency-induced
Bull, vol. 52, no. 2, pp. 151-154,
Hartwig A, “Role of magnesium
in
genomic
stability.”
2000
Mutat Re-
search, vol. 18, no. 475 (1-2), pp. 113-121, 2001 8.
Blaylock RL, Excitotoxins: The Taste That Fe,
9.
NM,
Nelson
Kills,
Health Press, Sante
1997
L, “Pesticides
and Parkinson’s Disease.” American Academy
CA,
of Neurology’s 52nd Annual Meeting, San Diego,
May 10.
2000
Blaylock RL, Excitotoxins: The Taste That Fe,
11.
6,
April 29-
NM,
Kills,
Health Press, Sante
1997
Rondeau
V
et
al.,
“Aluminum
cline in elderly subjects: the
in drinking
water and cognitive de-
Paquid cohort.”
Am J
Epidemiol, vol.
154, no. 3, pp. 288-290, 2001 12.
Rondeau
V
et
al.,
“Relation between aluminum concentrations in
drinking water and Alzheimer’s disease: an 8-year follow-up study.”
Am J Epidemiol, vol. 13.
Andrasi
E
et al.,
152, pp. 59-66,
2000
“Disturbances of magnesium concentrations in vari-
ous brain areas in Alzheimer’s disease.” pp. 189-196, 2000
266
Magues Res,
vol. 13, no. 3,
References
14.
M
Yasui
et
“Calcium, magnesium and aluminum concentrations
al.,
in Parkinson’s disease.” Neurotoxicology vol. 13, no. 3, pp. 593-600,
1992 15.
Blaylock RL, Excitotoxins: The Taste That Fe,
16.
NM,
1997
Durlach chapter
“Diverse applications of magnesium therapy. Part
J, 1,
Handbook
section B.
New York,
18.
NM,
Durlach cal
J et
al.,
“Magnesium and
Seelig
II.
Clinical data: aetiologi-
Magnes
Res, vol. 6, no. 4, pp. 379-394, 1993
14, pp.
of
magnesium by
the normal adult.”
342-390, 1964 in
human
nutrition.”
Magnes
26-47, 1981
Franz KB, “Magnesium intake during pregnancy.” Magnesium, vol. 6, pp. 18-27,
Seelig
1987
MS, “The requirement
Am J Clin Nutr, vol. Seelig
14, pp.
of
magnesium by
M
the normal adult.”
342-390, 1964
MS, “Magnesium requirements
Bull, vol. 3 (1A), pp. 6.
ageing.
MS, “Magnesium requirements
Bull, vol. 3 (1A), pp.
5.
Health Press, Sante
Kills,
mechanisms and pathophysiological consequences of magnesium
Am J Clin Nutr, vol.
4.
Marcel Dekker,
1997
CHAPTER 12 1. Seelig MS, “The requirement
3.
vol. 2,
1995
deficit in the elderly.”
2.
Medicine
Blaylock RL, Excitotoxins: The Taste That Fe,
five,
of metal-ligand interactions in bio-
logical fluids.” In: Bioinorganic
17.
Health Press, Sante
Kills
in
human
nutrition.”
Magnes
26-47, 1981
“Magnesium content of foodstuffs and beverages and magnesium intake of adults in Germany.” Magnes Bull, vol. 17, Glei
et
al.,
pp. 22-28, 1995 7.
Cashman
KD
et
al.,
“Optimal
phosphorous.” Proc Nutr 8.
Mircetic
nutrition: calcium,
Soc, vol. 58, pp.
RN, Dodig S, Raos M,
magnesium, and
477-487, 1999
Petres B, Cepelak
I,
“Magnesium con-
centration in plasma, leukocytes and urine of children with intermittent asthma.” Clin 9.
Ryzen E tion of
et al.,
Chim Acta,
“Parenteral
magnesium
vol. 312, nos. 1-2, pp. 197-203,
magnesium tolerance
deficiency.”
Magnesium,
1985
267
2001
testing in the evalua-
vol.
4,
pp.
137-147,
References
10.
Burton Altura, personal communication, November 2001
11.
Altura
BM,
Altura BT, “Role of magnesium in patho-physiological
processes and the clinical utility of trodes.” 12.
Scand J Clin Lab Invest Suppl,
Altura BT, Altura
BM, “A method
plexed and protein-bound
Mg
Scand J Clin Lab Invest Suppl, 13.
Altura
magnesium ion
BT
et
al.,
in
vol. 217, pp. 83-87,
“Comparative findings on serum
magnesium
in
NOVA
ized
Lab Invest Suppl, “A new method for the
BT et al., Mg2+ in whole
ings in 16.
and
1994
IMg2+
of normal
KONE
vol. 4, pp.
1994 electrode
21-36, 1994
rapid determination of ion-
and Find-
297-304, 1992
BM, “Measurement
whole blood, plasma and serum with in healthy
vol. 217, pp.
blood, serum and plasma.” Methods
Exp Clin Pharmacol,
Altura BT, Altura
ISE’s for
whole blood, plasma, serum, and aqueous
samples.” Scand J Clin
Altura
com-
normal and diseased subjects.”
Mg2 + .” Scand J Clin Lab Invest Suppl, vol. 217, pp. 77-81, Altura BT et al., “Characterization of a new ion selective for ionized
15.
211-234, 1996
for distinguishing ionized,
and diseased human subjects with the
14.
vol. 224, pp.
selective elec-
a
of ionized
new
magnesium
in
ion-selective electrode
and diseased human subjects.” Magnes Trace Elem,
vol. 10,
nos. 2-4, pp. 90-98, 1991-1992 17.
Altura BT, Altura
BM, “A method
plexed and protein-bound
Mg
Scand J Clin Lab Invest Suppl, 18.
Altura
BM,
in
for distinguishing ionized,
normal and diseased subjects.”
vol. 217, pp. 83-87, 1994
Altura BT, “Role of magnesium in patho-physiological
processes and the clinical utility of trodes.” Scand J Clin 19.
Lab
magnesium ion
21. Altura
Invest Suppl, vol. 224, pp. 211-234, 1996
communication with Burton Altura, November 2001
BT
et
al.,
“Clinical studies with the
Scand J Clin Lab Invest Suppl,
vol. 217, pp.
NOVA ISE for IMg2 +
Marcus JC, Altura BT, Altura BM, “Serum ionized magnesium Muneyvirci-Delale
O et
al.,
“Divalent cations in
3,
268
in
pp. 459-462, 2001
women with PCOS:
implications for cardiovascular disease.” Gynecol Endocrinol, vol.
pp. 198-201,2001
.”
53-67, 1994
post-traumatic headaches.”/ Pediatr, vol. 139, no. 23.
selective elec-
Ibid.
20. Personal
22.
com-
3,
References
24.
Marcus JC
“Serum ionized magnesium
et al.,
in
premature and term
infants.” Pediatr Neurol, vol. 4, pp. 311-314, 1998 25. Scott
VL et al.,
“
Ionized hypomagnesemia in patients undergoing or-
thotopic liver transplantation: a complication of citrate intoxication.”
Liver Transpl Surg vol. 26. Altura
BT
et al.,
“Low
2,
no.
levels of
calcium and spasm
rosci Lett vol. 230, no.
27.
J Am CollNutr
,
Memon
ZI
magnesium no. 29.
serum ionized magnesium
found
result in rapid elevation in cyto-
in cerebral vascular
muscle
Neu-
cells.”
pp. 37-40, 1997
1,
8,
in the antenatal period of
vol. 15, no.
1,
human
pregnancy.”
pp. 36-43, 1996
“Predictive value of serum ionized but not total
et al.,
levels in
head
injuries.”
Scand ] Clin Lab
Invest, vol. 55,
pp. 671-677, 1995
Handwerker SM, Altura BT, Altura BM, “Ionized serum magnesium and potassium
levels
in
pregnant
women
eclampsia.” / Reprod Medicine, vol. 40, no. 30. Drs. Bella
Durlach
3,
with preeclampsia and pp. 201-208, 1995
and Burton Altura, State University of
Science Center at Brooklyn, 31.
are
Handwerker SM, Altura BT, Altura BM, “Serum ionized magnesium and other electrolytes
28.
pp. 343-347, 1996
which
in patients early after stroke solic free
5,
J,
Bac
P,
New York,
Health
New York
Bara M, Guiet-Bara A, “Cardiovasoprotective
foods and nutrients: possible importance of magnesium intake.”
Magnes 32.
Res, vol. 12, no.
Wood M, Berkeley,
34.
Weed ing,
35.
pp. 57-61, 1999
Murray M, Encyclopedia of Nutritional Supplements, Prima Publishing, Rocklin,
33
1,
S,
CA,
1996
Seven Herbs: Plants
as Teachers,
North Atlantic Books,
CA, 1987
Llealing Wise: The Wise
Woman
Herbal, Ash Tree Publish-
Woodstock, NY, 1989
Duke JA, The Green Pharmacy,
St.
Martin’s Press,
New
York,
1998 36. Chevallier
37.
A, The Encyclopedia of Medicinal Plants,
New York, 1996 Marx A et al., “Magnesium in drinking water and ease.” Epididemiol Rev, vol. 19, pp. 258-272, 1997
269
DK
Publishing,
ischemic heart dis-
References
38.
Von Wiesenberger A, The Pocket Guide
to Bottled Water,
Contem-
porary Books, Chicago, 1991
CHAPTER 13 1.
Durlach J, Magnesium
2.
Fehlinger R, “Therapy with magnesium
Magnes 3.
Bull, vol. 12, pp. 35-42,
Ducroix
T, “L’enfant
peutiques.” 4.
Seelig
in Clinical Practice,
MS,
Magnes
Libbey, London, 1988.
salts in
neurological diseases.”
1990
spasmophile
—Aspects diagnostiques
Bull, vol. 1, pp. 9-15,
et thera-
1984
“Athletic stress, performance and
magnesium
in con-
sequences of magnesium deficiency on the enhancement of stress
and therapeutic implications:
reactions; preventive
Coll Nutr, vol. 13, no. 5.
Seelig
Johnson
S,
J
Am
pp. 429-446, 1994
MS, “Magnesium requirements
Bull, vol. 3 (1 A), pp. 6.
5,
a review.”
in
human
nutrition.”
Magnes
26-47, 1981
“The multifaceted and widespread pathology of magne-
Med Hypotheses, vol. 56, no. 2, pp. 163-170, 2001 “Low serum concentrations of 1,25-dihydroxyvitamin
sium deficiency.” 7.
Rude RK et al., D in human magnesium
deficiency.” / Clin Endocrinol Metah, vol. 61,
pp. 833-940, 1985 10. 8.
Fuss
M et
vitamin
D
al.,
“Correction of low circulating levels of 1,25-dihydroxy-
by 25-hydroxyvitamin
D
during reversal of hypomagne-
saemia.” Clinical Endocrinol Oxf, vol. 31, pp. 31-38, 1989 9.
Manuel y Keenoy B, Moorkens G, Vertommen J, Noe M, Neve J, De Leeuw I, “Magnesium status and parameters of the oxidantantioxidant balance in patients with chronic fatigue: effects of supple-
mentation with magnesium.” J pp. 374-382, 2000 Boericke
Am
Coll Nutr,
vol.
19,
no.
3,
OE, Pocket Manual of Homeopathic Materia Medica,
9th ed., Boericke
& Runyon, Philadelphia,
270
1927
Index
acne, 163
angina, 99-100, 101
acupuncture, 174
antacids, 32-33, 199, 201, 230
adrenaline, 19, 45, 49-50, 60, 66,
antibiotics, 8, 37, 38, 162, 163, 164,
67, 105, 169, 170
166, 179
aging, 190-203
antioxidants, 193-95
Alzheimer’s disease, 195-203
anxiety and panic attacks,
free radicals, antioxidants, and,
17,
45-55, 67, 165
magnesium and, 45-62
193-95
magnesium and, 190-203 alcohol, 36, 46, 69, 89, 100, 109, 128, 129, 142, 148, 149,
152,216
brain injury, and magnesium,
75-76
treatment for, 54-55 arrhythmia, 105-6 arteries, elasticity of,
84-86
arteriosclerosis, 87, 93 arthritis, 32, 141
allergies, 163, 167,
168
asthma and, 185-89 environmental, 173-74, 189
aluminum
5, 13,
toxicity,
196-203
aspartame, 64-66, 67, 90, 120, 138, 167, 199 aspirin, 72, 101, 189
asthma,
Alzheimer’s disease, 65, 73, 190,
5,
26, 28, 32, 163, 167, 171,
183-89,210,213 magnesium and, 183-89 treatment, 188-89 174,
195-203 treatment, 201-3
American Heart Association, 83 amino acids, 65, 91-93, 215
atherosclerosis, 87, 93-96, 98, 101,
anger, 48
ATP,
108, 149
271
16,
25,58
Index
magnesium,
attention deficit hyperactivity
disorder
(ADHD),
51, 66
9, 17, 19, 21, 28,
29, 112, 124, 130, 140-52, 231 8, 57, 58, 174 environmental toxins and, 174-76 magnesium and, 58 carbohydrates, 61, 66, 116, 118,
cancer,
back pain,
6, 18, 19,
134
birth control pills, 37, 164, 166
blood
clots, 5, 52,
68-69, 84, 92,
129,217
101, 102, 103 blood pressure, 3, 96
cardiac death syndrome, 61-62
high, see hypertension
blood sugar,
5, 13, 17, 48, 49, 96,
cardiovascular metabolic
bond
density,
(CVMS), 111-12, 113
100
low, 66-68
cells,
139-47
139-40 bone meal, 226-27 bowel disease, 5, 20 bowel obstruction, 226 bowel movements: loose, 225, 226, 229, 230 regular, 20
27 cerebral palsy, 7, 136-38 chelated magnesium, 227 chelation therapy, 107-8 chickweed, 220 metabolism,
3, 21,
children, 162, 163, 164, 207, 225, 234
asthma, 184, 186-87, 210 cerebral palsy, 136-38
brain, 23-24, 27, 52, 119
117-18 magnesium-deficient, 51-52 SIDS, 135-36
Alzheimer’s disease and, 195-203
damage, 136-38, 213 magnesium and, 63-80 surgery, and magnesium, 76-77,
diabetic,
chocolate, 127, 148 cholesterol, 20, 61, 81, 88-91, 92, 96, 109, 110, 113, 116, 117
78 root,
magnesium and, 88-91
219-20
LDL vs. HDL,
burns, third-degree, 8
cadmium, calcium,
21,27
death, 66
test,
burdock
syndrome
178, 197, 231
3, 13, 22, 23, 33, 50, 68,
76, 78, 80, 105, 119, 121, 126,
130, 147, 192,
193,209
deficiency, 16
and drug interactions
88-89
chronic fatigue syndrome, 60, 155-70, 172 magnesium and, 155-70 cilantro,
219
cluster headaches, 70-71 coffee, 36, 89, 105, 109, 129, 142,
148, 149
in heart
disease, 94, 95
excess, 13, 16, 23, 27, 28, 59, 86,
constipation,
134, 199
contraindications to
magnesium
therapy, 226
87, 107, 111, 140, 144, 231
kidney stones and, 147-52 magnesium and, 26-29, 112, 139-52, 221,231 in mineral water, 221-23 osteoporosis and, 139-47 supplementation with
5, 20,
cortisone, 37, 50, 162-64
cramps, leg, 9,
6,
9
13-14, 16, 49, 53,55-57,
233-34 15, 20, 26
61, 193,228,
menstrual, cystitis, 5
272
7,
Index
drugs, 37-38, 40, 46, 47, 97, 141, 166, 168, 191
dairy products, 34, 35, 90, 120, 127, 129, 140, 188, 202,216,
236, 237 dandelion, 220
depression,
antibiotics, 8, 37, 38, 162-64,
166, 179
5, 32,
antihypertensive, 97-98
45-62, 165, 167
asthma, 185-86 companies, 103 heart, 94-98, 103-4
magnesium and, 45-62
PMS
and, 128 treatment for, 54-55
interactions with
detoxification, 5, 20, 165, 166, 171,
174 treatments, 178-83 diabetes, 5,
8,
38,
prescription, taking
for,
120-21
psychiatric, 46, 52, 53, 165
magnesium and, 113-21 symptoms and complications,
smart, 192 see also specific drugs
115-16 I,
II,
by, 8, 37, 79
magnesium
with, 83
and supplements
Type Type
94-95
magnesium depleted
14, 32, 100, 113-21,
131, 192, 193,213 diet
magnesium,
dulse, 220,
221,235
dysmenorrhea,
113, 115, 116
7, 16,
20, 26, 130, 164
113-14, 115
diarrhea, 225, 226, 229, 230
ear infections, 162-63
diet, 141, 191
for anxiety, 54
132-34, 213 eczema, 174, 183 EKG, 99
for asthma, 188-89
electrical transmission,
for diabetes, 120
energy, 24, 59, 60, 116 production and transport, 25
eclampsia,
for Alzheimer’s disease, 202
'
for environmental illness, 179-80
for heart disease, 109 for kidney stones, 152
magnesium
in, 3-4, 16-17, 19, 207-8, 215-23, 235-37 21, 33, magnesium content of selected foods, 218-19, 235-37 for osteoporosis, 145-47 PMS and, 127-29
for Raynaud’s
syndrome, 56-57
RDA of magnesium in, 4, 30,
essential fatty acids, 126, 128-30,
digitalis,
188,215, 232
magnesium
deficiency,
215-23
estrogen, 68, 124, 125, 128
replacement, 144, 165 excitiotoxins, 65-68, 78
37
diuretics, 8, 36, 37, 38, 69, 79, 94,
exercise, 20, 55, 145, 168, 191, 203,
97, 103, 151, 199
magnesium and,
DNA,
3, 24, 26,
23-24
environmental illness, 171-89, 196 CFS and, 155-70 pesticides and, 174-76, 179-80 treatment, 178-83 enzymes, magnesium-dependent, 3,20,21,24, 25, 27, 176-77, 196-97 Epsom salts, 4, 22, 229 Epstein-Barr virus, 156, 157
207-8, 224 solutions to
7,
79,
225
94-95
lack of, 141, 142
magnesium and, 58-62
194
273
Index
fast
food, 14, 20, 32, 35-36, 51, 61, 89, 142
heart rate, slow, 226
herb sources of magnesium, 219-21
34,61, 109, 194,218 cholesterol and, 89-91
fat(s),
homeopathic magnesium, 174, 232-34
saturated, 34, 89, 90, 128, 129,
216
homocysteine, 91-93, 96 homocysteinuria, 91-93
fatigue, 5-6, 45, 49, 169, 170
hormonal imbalance,
chronic fatigue syndrome,
155-70
hydrogenated
6, 27, 149, 160-70,
172, 228
oils,
90-91
hyperactivity, 51
magnesium and,
155,
160-70
hypertension,
149
6, 7, 8, 18,
96-98,110,113, 119, 131, 147, 192,213 magnesium and, 96-98 pregnancy-induced, 132-34 hypoglycemia, 6, 48, 66-68 hypothyriodism, 88, 164
fruits, 109, 145, 152, 188, 216, 217,
236, 237
immune system, 50, CFS and, 155-70
gas and bloating, 230
gender, 15-16, 30-31, 68, 83, 207,
225
157, 162
infertility, 7, 131, 164, 1 1
26, 81,
82, 83, 86,
188,216,217, 232 food additives, 63-68 free radicals, 76, 96, 102, 193-95 fish, 128, 145,
glucose,
68,
105, 124-26, 141
fibromylagia,
fibrositis, 6,
8, 15,
1-21
165
6, 45, 49 insulin, 5, 17, 37, 66-67, 110, 112, 113-21
insomnia,
grains, 16, 17, 34, 36, 89, 109, 120,
127, 145, 152,216,217-19,
236
grapefruit juice, 94
resistance, 110-12, 118, 131,
greens, 16, 17,21, 145,216, 236
132, 192
Internet, 2
head injury, 73-76 alcohol, and magnesium, 75-76 magnesium and, 73-75 heart, 3, 6, 14, 23-24,27, 73 palpitations, 13, 14, 17, 49 heart attack, 81, 82, 84-86, 99, 101-4 magnesium and, 101-4 road to, 84-86 heart disease,
6,
14-15, 17-19, 23,
34,41-42, 50, 72,81-109, 110, 119, 141, 192,213,222 magnesium and, 81-109 supplement and drug interactions in, 94-95
intravenous magnesium, 101, 102, 133 ions,
magnesium,
74, 75, 76, 79,
82, 117, 124, 125, 131,212-14
iron, 33, 38, 95, 127, 201
bowel, 164 ISIS trial, 103
irritable
junk food,
14, 20, 32,
35-36, 51,
100, 116-17, 165, 166, 202
28,
see also specific types of heart disease
8, 76, 77,
kidney disease, 6, 27, 98 kidney failure, 226 kidney stones, 27, 139-42, 147-52 diet and supplements for, 152 magnesium and, 147-52
274
Index
/
lactic acid
buildup, 59, 60, 69,
lactose, 33 laxative,
magnesium
as,
229
201,226, 231 cramps, 9, 13-14, 16, 49, 53, 55-57,61, 193,228, 233-34 legumes, 16, 17, 21, 34, 120, 145, 216, 236 LIMIT trial, 102, 103, 104 lead, 178, 197,
leg
liver disease, 8
low
MS,
166, 169
MSG,
168-69
65-66, 167, 199 muscles, 3, 25, 27 cramps, 6, 9, 13-14, 16, 49, 53, 55-57,61, 193, 228, 233-34 magnesium and, 54-58 pain, 6, 18, 57-58, 155, 160-70 relaxing, 26 spasms, 6, 26, 27, 49, 55-58, 61,
149, 234 myasthenia gravis, 226
birth weight infants, 136-38 narcotics, 38, 46
magnesia phosphorica, 233-34 magnesium, 2-9 blocked by certain foods, 34-35 calcium and, 26-29, 112, 139-52, 221,231 chemistry of, 21-23 deficient-conditions, 4-8,
43-152 function of, 24-26 history of, 4, 13-29
malabsorption disorders,
8,
32-33
meat, 34, 35, 89, 90, 127-30, 148,
188,216,217, 237 antibiotics in, 179-80 memory loss, 48
menopause,
15, 35, 144,
145
menstruation, 68, 69, 122, 164 cramps, 7, 15, 20, 26 painful, see
dysmenorrhea
National Academy of Sciences, 4, 30 neck pain, 6 nerves, 3, 25 problems, 7 transmitting signals, 26 nervous system, 50, 65, 67, 1 19, 200-201 nettles, 221 neurotransmitters, 65, 69, 80 nitric oxide (NO), 88 nuts 16, 17,21,31,36, 109, 127, 128, 145,216,218-19, 232, 235, 236 obesity, 14, 97, 110, 116, 117, 119 olive oil, 109
organic foods, 16, 32, 36-37, 147, 165, 174, 179-80, 203,216-17,
PMS, 122-30
219
mercury, 177-78, 197, 203 metal toxicity, 177-78, 190, 193,
osteoporosis,
6, 7, 15, 28, 42, 63, 66,
67, 68-72, 76, 124, 125, 131
magnesium and, 63-64, 68-72 treatment, 71
119,
139-47 diet and supplements for, 145-47 magnesium and, 139-47 mistreated, 143-45
196-203 migraines,
7, 16, 32, 38,
oxalic acid, 34
mineral water and magnesium,
221-23 mitral valve prolapse
106-7
painkillers, 8
(MVP).
pancreas, 8
Parkinson’s disease, 190, 195-97
275
BOSTON PUBLIC LIBRARY
3 9999 04656 508 9 s
Ca^lyn diS^tbr,
Dean, M.D., N.D.,
activist,
is
a medical doctor, naturopathic
environmentalist,
acupuncturist,
herbalist, clinical nutritionist, writer, researcher,
focus of her medical practice, from
its
homeopath,
and inventor. The
inception in 1979, was to
teach people about natural options and choices to achieve opti-
mum
Dean and her business partner, Delia Quigley, launched Halo Works organic herbal tinctures and began offering the Body Rejuvenation Cleanse Program in New York. Dr. Dean s Web site is www.carolyndean.com. health. In 2002, Dr.
“Magnesium
know
about.
quality of
indeed the unsung hero and
is .
.
.
life.
key nutriceutical that everybody needs to
is a
This book needs to be read by any individual wishing to improve their ... Dr. Dean has the best credentials
suffering from the hidden
-Dr.
magnesium disorders
Stephen
Author of
in
bringing solutions to those
that affect
most of us.”
Sinatra, M.D., F.A.C.C., F.A.C.N.
T.
Lower Your Blood Pressure in Eight Weeks
More than seventy-five years ago, medical essential nutrient, indispensable to
guarding against— and helping
life.
scientists declared
When
magnesium
this mineral is part of
your
to
diet,
be an
you are
alleviate— health threats such as heart disease,
to
stroke, osteoporosis, diabetes, depression, arthritis,
and asthma. But while research
many
continues to reaffirm magnesium's irreplaceable contribution to good health,
Americans remain dangerously In
The Miracle of Magnesium
has used
it
deficient.
with dramatic success
magnesium plays in the control spasms and bladder problems pregnancy and
who
Carolyn Dean, an authority on this mineral
Dr.
,
in
own
her
of
many
to
traumatic
practice, explains the vital role that
serious ailments brain
injury
—from
painful
muscle
and complications
of
childbirth.
Inside you will discover •
How diets and
•
Which magnesium-rich foods keep your which foods
lifestyles
to
can create a dangerous magnesium deficiency vital
organs healthy and
avoid
•
Why
•
What vitamins and minerals work
•
Why prescription
•
Which magnesium supplements are best
other nutrients, including calcium, with
medicines such as ,
need magnesium
magnesium
become
to treat specific
birth control pills,
for
to
It
may
you already
enjoy. The Miracle of
even save your
you
and
Magnesium
will
answer
all
protect the
good
your questions.
life.
Carolyn Dean, M.D. # N.D., herbalist,
ailments
can deplete magnesium
Whether you need help with a serious health problem or merely want to health
potent
is
a medical doctor, naturopath, acupuncturist, homeopath,
and a regular guest on radio and television other health books and is a contributing editor to
certified clinical nufritionist,
programs. She has written three Natural Health magazine.