Table of contents : Introduction Chapter 1. Background and Concepts Chapter 2. Symptoms and Diagnosis of Autism Chapter 3. Evidence of Genetic and Epigenetic Risk Components of Autism and Autism Spectrum Disorder Chapter 4. Speech, Language, and Communication Phenotypes in ASD Chapter 5. Genetic and Environmental Factors that Influence Social Cognitive Skills in ASD Chapter 6. Cognitive Phenotypes in ASD Chapter 7. Repetitive Motor Behaviors and Seizure Phenotypes Chapter 8. Sensory Phenotypes and Sensory Processing Disorder Chapter 9. Immunological Factors in Autism and ASD Chapter 10. Gastrointestinal and Renal Phenotypes in ASD Chapter 11. Neurotoxin-Induced Autoimmune-Mediated Neurological Damage in Autism Chapter 12. Vaccine-Autism Studies Ignored by the CDC Chapter 13. Concepts of Comorbidity in Autism and Autism Research Chapter 14. Study Designs for Meaningful Future Causal Research in Autism Chapter 15. Biological Pathways and Networks Views of Autism Chapter 16. Toward a Multidimensional Matrix Risk Model for Autism Chapter 17. The Logic of Prevention in Autism and Gene-Informed Treatment Chapter 18. Injecting Objective Association and Causal Inference into Clinical Trials, Prevention, Diagnosis, and Treatment of ASD