The Bethesda Handbook of Clinical Oncology [5th Edition] 9781496344182, 1496344189, 9781496367167, 1496367162
The Bethesda Handbook of Clinical Oncology is a comprehensive review of the management of numerous cancer types, emphasi
318 98 9MB
English Pages 768 Year 2018
Table of contents :
Contributors vi
Preface x
Acknowledgements xi
Section 1 Head and Neck
Chapter 1 Head and Neck Cancer Carter Van Waes Karl E. Hagiund Barbara A. Conley 001
Section 2 Thorax
Chapter 2 a Non-Small Cell Lung Cancer Anish Thomas Christina Brzezniak Giuseppe Giaccone 031
Chapter 3 Small Cell Lung Cancer Jarushka Naidoo Oscar S. Breathnach 044
Section 3 Digestive System
Chapter 4 Esophageal Cancer Mark K. Doherty Gregory D. Leonard 055
Chapter 5 Gastric Cancers Ellie E. Chan Thomas J. George, Jr. 066
Chapter 6 Biliary Tract Cancer Nilay A. Shall Jon Cardinal 083
Chapter 7 Primary Cancers of the Liver Midhun Malla David P. Cosgrove 095
Chapter 8 Colorectal Cancer Jennifer M. Duff Thomas J. George, Jr. 105
Chapter 9 Pancreatic Cancer Austin Duffy Christopher Ryan Heery Tim F. Greten 123
Chapter 10 Anal Cancer Stephen Ko 129
Chapter 11 Other Gastrointestinal Tumors Joleen M. Hubbard 143
Section 4 Breast
Chapter 12 Breast Cancer Brendan Curley Hannah W. Hazard Geraldine Jacobson Jame Abraham 153
Section 5 Genitourinary
Chapter 13 Renal Cell Cancer Ramaprasad Srinivasan Inger Lerra Rosner W. Marston Linehan 177
Chapter 14 Prostate Cancer Ravi A. Madan William L. Dahut 191
Chapter 15 Bladder Cancer Andrea B. Apolo William L. Dahut 208
Chapter 16 Testicular Carcinoma Bamiidele A. Adesunloye Ravi A. Madan 218
Section 6 Gynecologic
Chapter 17 Ovarian Cancer Jung-min Lee Alexandre Buckley de Meritens Dominic H. Moon Eiise C. Kohn 233
Chapter 18 Endometrial Cancer Anne M. Noonan Christina M. Antiunziata 243
Chapter 19 Cervical Cancer Sharon Romano Fitzgerald Michael P. Stany Chad A. Hamilton 252
Chapter 20 Vulvar Cancer Anne M. Noonan Christina M. Annunziata 264
Section 7 Musculoskeletal
Chapter 21 Sarcomas and Malignancies of the Bone Patrick J. Mansky Lee J. Helman 271
Section 8 Skin
Chapter 22 Skin Cancers and Melanoma Upendra P. Hegde Sanjiv S. Agarwala 285
Section 9 Hematologic Malignancies
Chapter 23 Acute Leukemia Aaron Cumpston Michael Craig 307
Chapter 24 Chronic Lymphoid Leukemias Chaitra S. Ujjani Bruce D. Cheson 321
Chapter 25 Chronic Myeloid Leukemia Sairah Ahmed Muzaffar H. Qazilbash 328
Chapter 26 Chronic Myeloproliferative Neoplasms Yogen Saunthararajah 335
Chapter 27 Multiple Myeloma Preet Paul Singh Shaji K. Kumar 343
Chapter 28 Non-Hodgkin Lymphoma Clifton Mo Mark Roschewski Kieron Dunleavy Wyndham Wilson 361
Chapter 29 Hodgkin Lymphoma Mehdi Hamadani Elaine S. Jaffe 374
Chapter 30 Hematopoietic Cell Transplantation Abraham S. Kanate Michael Craig Richard W. Childs 385
Section 10 Other Malignancies
Chapter 31 Carcinoma of Unknown Primary Hung T. Khong 399
Chapter 32 Central Nervous System Tumors Christopher Ryan Heery Teri Kreisl 407
Chapter 33 Endocrine Tumors Ann W. Gramza 424
Section 11 Supportive Care
Chapter 34 Hematopoietic Growth Factors Joseph Woong Kim Nishith K. Singh Philip M. Arlen 439
Chapter 35 Infectious Complications in Oncology Mauricio Burotto Pichún Sarah Rend Juan C. Gea-Banacloche 448
Chapter 36 Oncologic Emergencies and Paraneoplastic Syndromes Govardhanan Nagaiah Quoc Truong Manish Monga 468
Chapter 37 Psychopharmacologic Management in Oncology Donald L. Rosenstein Maryland Pao Sheryl B. Fleisch Daniel E. Elswick 480
Chapter 38 Management of Emesis David R. Kohler 490
Chapter 39 Medical Nutrition Therapy Marnie G. Dobbin 518
Chapter 40 Pain and Palliative Care Erie G. Bush Anne Berger 528
Chapter 41 Central Venous Access Device Uzer Khan Hannah W. Hazard 534
Section 12 Common Office Procedures and Other Topics
Chapter 42 Procedures in Medical Oncology Kerry Ryan George L. Carter Suzanne G. Demko 543
Chapter 43 Diagnosis-Driven Individualization of Cancer Care Philippe C. Bishop Chris Bowden Garret Hampton Lukas Amler 552
Chapter 44 Basic Principles of Radiation Oncology Deborah Citrin 559
Chapter 45 Clinical Genetics Julie Nangia Annie Sn Sarah Zentack 566
Chapter 46 Anticancer Agents Lindsay C. Stansfield Thomas E. Hughes 577
Appendices
Appendix 1 697
Appendix 2 Answers to Review Questions 699
Index 727
Contributors vi
Preface x
Acknowledgements xi
Section 1 Head and Neck
Chapter 1 Head and Neck Cancer Carter Van Waes Karl E. Hagiund Barbara A. Conley 001
Section 2 Thorax
Chapter 2 a Non-Small Cell Lung Cancer Anish Thomas Christina Brzezniak Giuseppe Giaccone 031
Chapter 3 Small Cell Lung Cancer Jarushka Naidoo Oscar S. Breathnach 044
Section 3 Digestive System
Chapter 4 Esophageal Cancer Mark K. Doherty Gregory D. Leonard 055
Chapter 5 Gastric Cancers Ellie E. Chan Thomas J. George, Jr. 066
Chapter 6 Biliary Tract Cancer Nilay A. Shall Jon Cardinal 083
Chapter 7 Primary Cancers of the Liver Midhun Malla David P. Cosgrove 095
Chapter 8 Colorectal Cancer Jennifer M. Duff Thomas J. George, Jr. 105
Chapter 9 Pancreatic Cancer Austin Duffy Christopher Ryan Heery Tim F. Greten 123
Chapter 10 Anal Cancer Stephen Ko 129
Chapter 11 Other Gastrointestinal Tumors Joleen M. Hubbard 143
Section 4 Breast
Chapter 12 Breast Cancer Brendan Curley Hannah W. Hazard Geraldine Jacobson Jame Abraham 153
Section 5 Genitourinary
Chapter 13 Renal Cell Cancer Ramaprasad Srinivasan Inger Lerra Rosner W. Marston Linehan 177
Chapter 14 Prostate Cancer Ravi A. Madan William L. Dahut 191
Chapter 15 Bladder Cancer Andrea B. Apolo William L. Dahut 208
Chapter 16 Testicular Carcinoma Bamiidele A. Adesunloye Ravi A. Madan 218
Section 6 Gynecologic
Chapter 17 Ovarian Cancer Jung-min Lee Alexandre Buckley de Meritens Dominic H. Moon Eiise C. Kohn 233
Chapter 18 Endometrial Cancer Anne M. Noonan Christina M. Antiunziata 243
Chapter 19 Cervical Cancer Sharon Romano Fitzgerald Michael P. Stany Chad A. Hamilton 252
Chapter 20 Vulvar Cancer Anne M. Noonan Christina M. Annunziata 264
Section 7 Musculoskeletal
Chapter 21 Sarcomas and Malignancies of the Bone Patrick J. Mansky Lee J. Helman 271
Section 8 Skin
Chapter 22 Skin Cancers and Melanoma Upendra P. Hegde Sanjiv S. Agarwala 285
Section 9 Hematologic Malignancies
Chapter 23 Acute Leukemia Aaron Cumpston Michael Craig 307
Chapter 24 Chronic Lymphoid Leukemias Chaitra S. Ujjani Bruce D. Cheson 321
Chapter 25 Chronic Myeloid Leukemia Sairah Ahmed Muzaffar H. Qazilbash 328
Chapter 26 Chronic Myeloproliferative Neoplasms Yogen Saunthararajah 335
Chapter 27 Multiple Myeloma Preet Paul Singh Shaji K. Kumar 343
Chapter 28 Non-Hodgkin Lymphoma Clifton Mo Mark Roschewski Kieron Dunleavy Wyndham Wilson 361
Chapter 29 Hodgkin Lymphoma Mehdi Hamadani Elaine S. Jaffe 374
Chapter 30 Hematopoietic Cell Transplantation Abraham S. Kanate Michael Craig Richard W. Childs 385
Section 10 Other Malignancies
Chapter 31 Carcinoma of Unknown Primary Hung T. Khong 399
Chapter 32 Central Nervous System Tumors Christopher Ryan Heery Teri Kreisl 407
Chapter 33 Endocrine Tumors Ann W. Gramza 424
Section 11 Supportive Care
Chapter 34 Hematopoietic Growth Factors Joseph Woong Kim Nishith K. Singh Philip M. Arlen 439
Chapter 35 Infectious Complications in Oncology Mauricio Burotto Pichún Sarah Rend Juan C. Gea-Banacloche 448
Chapter 36 Oncologic Emergencies and Paraneoplastic Syndromes Govardhanan Nagaiah Quoc Truong Manish Monga 468
Chapter 37 Psychopharmacologic Management in Oncology Donald L. Rosenstein Maryland Pao Sheryl B. Fleisch Daniel E. Elswick 480
Chapter 38 Management of Emesis David R. Kohler 490
Chapter 39 Medical Nutrition Therapy Marnie G. Dobbin 518
Chapter 40 Pain and Palliative Care Erie G. Bush Anne Berger 528
Chapter 41 Central Venous Access Device Uzer Khan Hannah W. Hazard 534
Section 12 Common Office Procedures and Other Topics
Chapter 42 Procedures in Medical Oncology Kerry Ryan George L. Carter Suzanne G. Demko 543
Chapter 43 Diagnosis-Driven Individualization of Cancer Care Philippe C. Bishop Chris Bowden Garret Hampton Lukas Amler 552
Chapter 44 Basic Principles of Radiation Oncology Deborah Citrin 559
Chapter 45 Clinical Genetics Julie Nangia Annie Sn Sarah Zentack 566
Chapter 46 Anticancer Agents Lindsay C. Stansfield Thomas E. Hughes 577
Appendices
Appendix 1 697
Appendix 2 Answers to Review Questions 699
Index 727
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