Serotonin Receptors And Their Ligands 978-0-444-82041-9

An international group of authors have produced an overview of the progress made in the medicinal chemistry of compounds

282 52 132KB

English Pages 3-367 [379] Year 1997

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Table of contents :
Content:
Preface
Page vii

5-Hydroxytryptamine receptor subtypes Original Research Article
Pages 3-13
Stephen J. Peroutka

5-HT1A receptor ligands Original Research Article
Pages 17-43
I. van Wijngaarden, W. Soudijn, M.Th.M. Tulp

Structural characteristics of 5-HT1A receptors and their ligands Original Research Article
Pages 45-64
W. Kuipers

5-HT1A receptor coupling to G-proteins
Pages 65-66
W. Soudijn

Ligand binding assays Original Research Article
Pages 67-71
M.Th.M. Tulp, I. van Wijngaarden

5-HT1A behavioural models Original Research Article
Pages 73-79
J. Mos, B. Olivier

Therapeutic applications 5-HT1A receptor ligands Original Research Article
Pages 81-83
I. van Wijngaarden

5-HT1B receptor ligands Original Research Article
Pages 87-95
I. van Wijngaarden, W. Soudijn

5-HT1B Receptors
Pages 97-98
W. Kuipers

5-HT1D receptors Original Research Article
Pages 101-138
D.N. Middlemiss, M.S. Beer, V.G. Matassa

5-HT1E and 5-HT1F receptors Original Research Article
Pages 141-157
G. McAllister, J.L. Castro

5-HT2A, 5-HT2B and 5-HT2C receptor ligands Original Research Article
Pages 161-197
I. van Wijngaarden, W. Soudijn

The 5-HT2-type receptor family Original Research Article
Pages 199-214
E. Ronken, B. Olivier

5-HT2 receptor antagonists: (potential) therapeutics Original Research Article
Pages 215-217
W. Soudijn

5-HT3 receptors Original Research Article
Pages 221-258
H. Gozlan

5-HT4 receptors Original Research Article
Pages 261-308
A. Dumuis, H. Ansanay, C. Waeber, M. Sebben, L. Fagni, J. Bockaert

The 5-HT5, 5-HT6 and 5-HT7 receptors Original Research Article
Pages 311-323
R. Grailhe, U. Boschert, R. Hen

5-HT transporter Original Research Article
Pages 327-361
W. Soudijn, I. van Wijngaarden

Index
Pages 363-367

Serotonin Receptors And Their Ligands
 978-0-444-82041-9

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