Oncolytic Viruses 1493997939

Table of contents :
Front Matter ....Pages i-xi
Introduction to Oncolytic Virotherapy (Christine E. Engeland, John C. Bell)....Pages 1-6
Methods for Modification of Therapeutic Viruses (Claudia A. P. Hill, Luca Bau, Robert Carlisle)....Pages 7-29
Tumor Targeting of Oncolytic Adenoviruses Using Bispecific Adapter Proteins (Julia Niemann, Florian Kühnel)....Pages 31-49
Development of Entry-Targeted Oncolytic Measles Viruses (Michael D. Mühlebach, Roberto Cattaneo)....Pages 51-75
Insert Stability and In Vivo Testing of MicroRNA-Detargeted Oncolytic Picornaviruses (Autumn J. Schulze)....Pages 77-94
Ex Vivo Virotherapy with Myxoma Virus to Treat Cancer (Nancy Y. Villa, Lina S. Franco, Grant McFadden)....Pages 95-110
Immunomodulation in Oncolytic Measles Virotherapy (Laura Dietz, Christine E. Engeland)....Pages 111-126
A Functional Assay to Determine the Capacity of Oncolytic Viruses to Induce Immunogenic Tumor Cell Death (Tiphaine Delaunay, Carole Achard, Marc Grégoire, Frédéric Tangy, Nicolas Boisgerault, Jean-François Fonteneau)....Pages 127-132
Design and Production of Newcastle Disease Virus for Intratumoral Immunomodulation (Gayathri Vijayakumar, Dmitriy Zamarin)....Pages 133-154
Analysis of Immunological Treatment Effects of Virotherapy in Tumor Tissue (Krishna Das, Carles Urbiola, Bart Spiesschaert, Philipp Mueller, Guido Wollmann)....Pages 155-177
Immunohistochemistry for Tumor-Infiltrating Immune Cells After Oncolytic Virotherapy (Dipongkor Saha, Samuel D. Rabkin)....Pages 179-190
Detection of Tumor Antigen-Specific T-Cell Responses After Oncolytic Vaccination (Jonathan G. Pol, Byram W. Bridle, Brian D. Lichty)....Pages 191-211
Evaluation of Oncolytic Virus-Induced Therapeutic Tumor Vaccination Effects in Murine Tumor Models (Rūta Veinalde)....Pages 213-227
Delivery of Oncolytic Reovirus by Cell Carriers (Elizabeth J. Ilett)....Pages 229-236
In Vivo Bioimaging for Monitoring Intratumoral Virus Activity (Liesa-Marie Schreiber, Carles Urbiola, Patrik Erlmann, Guido Wollmann)....Pages 237-248
Oncolytic Immunotherapy for Bladder Cancer Using Coxsackie A21 Virus: Using a Bladder Tumor Precision-Cut Slice Model System to Assess Viral Efficacy (Kate Relph, Nicola Annels, Chris Smith, Marcos Kostalas, Hardev Pandha)....Pages 249-259
Use of Liquid Patient Ascites Fluids as a Preclinical Model for Oncolytic Virus Activity (Eleanor M. Scott, Sally Frost, Hena Khalique, Joshua D. Freedman, Len W. Seymour, Janet Lei-Rossmann)....Pages 261-270
Generating Primary Models of Human Cancer to Aid in the Development of Clinically Relevant Oncolytic Viruses (Brian A. Keller, Marie-Ève Wedge, Abera Surendran, Carolina S. Ilkow)....Pages 271-284
Considerations for Clinical Translation of MG1 Maraba Virus (Caroline J. Breitbach)....Pages 285-293
Fluorescence In Situ Hybridization (FISH) Detection of Viral Nucleic Acids in Oncolytic H-1 Parvovirus-Treated Human Brain Tumors (Irina Kiprianova, Alexandra Just, Barbara Leuchs, Jean Rommelaere, Assia L. Angelova)....Pages 295-306
Mathematical Modeling of Oncolytic Virotherapy (Johannes P. W. Heidbuechel, Daniel Abate-Daga, Christine E. Engeland, Heiko Enderling)....Pages 307-320
Back Matter ....Pages 321-329