Neurobiology of mental illness [Fourth edition] 9780199398461, 0199398461, 9780199934959, 0199934959

Table of contents :
SECTION 1: Introduction to Basic Neuroscience / Eric J. Nestler --
Overview of Brain Development / John L.R. Rubenstein --
Neurochemical Systems in the Central Nervous System / Ariel Y. Deutch and Robert H. Roth --
Principles of Electrophysiology / Evelyn K. Lambe --
Principles of Signal Transduction / Jean-Antoine Girault and Paul Greengard --
Synaptic and Neural Plasticity / Saïd Kourrich and Antonello Bonci --
Principles of Molecular Biology / Steven E. Hyman and Eric J. Nestler --
Epigenetics of Psychiatric Diseases / Bryan E. McGill and Huda Y. Zoghbi --
SECTION 2: Emerging Technologies /Karl Deisseroth --
Transgenic Tools and Animal Models of Mental Illness / Lisa M. Monteggia, William Carlezon, Jr. and Ralph J. DiLeone --
Application of Stem Cells to Understanding Psychiatric Disorders / Kimberly M. Christian, Hongjun Song and Guo-li Ming --
Optogenetic Technologies for Psychiatric Disease Research: Current Status and Challenges / Lief E. Fenno and Karl Deisseroth --
Applications of Focused Ultrasound / Elisa E. Konofagou --
Genetic Methodologies and Applications / Shaun M. Purcell --
The Brain and Its Epigenome / Amanda C. Mitchell, Yan Jiang, Cyril J. Peter, Ki A. Goosens and Schahram Akbarian --
Network Methods for Elucidating the Complexity of Common Human Diseases / Eric E. Schadt --
Brain Imaging Methodologies / Hanzhang Lu, Yihong Yang and Peiying Liu --
Image-Guided Brain Stimulation / Mark S. George, John J. Taylor and Jaimie Henderson --
SECTION 3: Psychotic Disorders / Pamela Sklar --
Diagnosis of the Psychoses / Lianne Morris Smith, Julie W. Messinger and Dolores Malaspina --
Genetics of Schizophrenia and Bipolar Disorder / Pamela Sklar --
Genomic Syndromes in Schizophrenia: Overlapping Phenotypes / George Kirov, Michael O'Donovan and Michael J. Owen --
Neuroimaging of Psychotic Disorders / Stephan Heckers, Neil Woodward and Dost Ongur --
Cognitive and Motivational Neuroscience of Psychotic Disorders / Alan Anticevic, Erin C. Dowd and Deanna M. Barch --
Mouse Models of Schizophrenia and Bipolar Disorder / Mikhail V. Pletnikov and Christopher A. Ross --
Cortical GABA Neurons in Schizophrenia / Allison A. Curley and David A. Lewis Synaptic --
Disease in Psychiatry / Seth G.N. Grant --
Neurodevelopment and Schizophrenia / Ester J. Kwon, Takahiro Soda and Li-Huei Tsai --
Psychosis Proneness / Raquel E. Gur --
Neurochemistry and Pharmacotherapy / Carol A. Tamminga and Elena I. Ivleva --
Neurobiology of Bipolar Disorder / Kate Burdick, Stephen Haggarty and Roy Perlis --
SECTION 4: Mood Disorders / Helen S. Mayberg --
The Diagnosis of Mood Disorders / Jan Fawcett and Brant Hager --
Genetics of Depression / Douglas F. Levinson --
Animal Models of Mood Disorders / Georgia E. Hodes and Scott J. Russo --
Molecular and Cellular Pathogenesis of Depression and Mechanisms for Treatment Response / Ronald S. Duman --
Pathogenesis of Depression: Clinical Studies / Maura A. Furey, Daniel C. Mathews and Carlos A. Zarate Jr. --
Neural Circuitry of Depression / Joseph L. Price and Wayne C. Drevets --
Neurobiology of Depression in Later Life: Anatomy of Melancholia / K. Ranga Rama Krishnan --
Gonadal Steroids and Mood Disorders / David R. Rubinow, Peter J. Schmidt and Claire D. Craft --
Depression and Medical Illness / Tami D. Benton, Joshua Blume, Paul Crits-Christoph, Benoit Dube and Dwight L. Evans --
Treatments for Depression / Dan V. Iosifescu, James W. Murrough and Dennis S. Charney --
SECTION 5: Anxiety Disorders / Kerry J. Ressler --
Diagnosis of Anxiety Disorders / Meghan E. Keough, Murray B. Stein and Peter P. Roy-Byrne --
Genetics of Anxiety Disorders / Javier A. Perez, Takeshi Otowa, Roxann Roberson-Nay and John M. Hettema --
The Neurobiology of Fear and Anxiety: Contributions of Animal Models to Current Understanding / Christopher K. Cain, Gregory Sullivan and Joseph E. LeDoux --
Differential roles of GABA Receptors in Anxiety / Hanns Möhler --
Prefrontal Cortex Regulation of Emotion and Anxiety / Bronwyn M. Graham and Mohammed R. Milad --
Developmental Components of Fear and Anxiety in Animal Models / Siobhan S. Pattwell, Anne-Marie Mouly, Regina M. Sullivan and Francis S. Lee Functional --
Neurocircuitry and Neuroimaging Studies of Anxiety Disorders / Madeleine S. Goodkind, Anett Gyurak and Amit Etkin --
Novel Treatment Approaches for Anxiety Disorders / Anita Van Zwieten, Gail A. Alvares & Adam J. Guastella --
Pharmacotherapy of Anxiety Disorders / Dan V. Iosifescu, James W. Murrough and Dennis S. Charney --
Neurobiology and Treatment of OCD / Susanne E. Ahmari and H. Blair Simpson --
Neurobiology and Treatment of PTSD / Karen E. Murray, Orion P. Keifer, Jr., Kerry J. Ressler, Seth Davin Norrholm and Tanja Jovanovic --
SECTION 6: Substance Use Disorders / Antonello Bonci and Nora Volkow --
Animal Models of Addiction / Christopher J. Evans, Rafael Maldonado López and Yvette F. Taché --
Cellular and Molecular Mechanisms of Addiction / Kathryn J. Reissner and Peter W. Kalivas --
The Genetic Basis of Addictive Disorders / David Goldman --
Brain Development and the Risk for Substance Abuse / Kristina Caudle and BJ Casey --
Molecular Imaging in Addictive Disorders / Chelsea L. Robertson, Steven M. Berman and Edythe D. London --
Brain, Reward, and Drug Addiction / Vani Pariyadath, Martin P. Paulus and Elliot A. Stein --
Magnetic Resonance Spectroscopy Studies in Substance Abusers / Linda Chang, Christine C. Cloak and John L. Holt --
Pharmacotherapy of Substance Use Disorders / Jane B. Acri and Philip Skolnick --
Epidemiology of Substance Use Disorders / Denise B. Kandel, Mei-Chen Hu and Pamela C. Griesler --
SECTION 7: Dementia / David M. Holtzman --
Clinical and Neuropsychological Features of Alzheimer's Disease / Jason Hassenstab, Jeffrey Burns and John C. Morris --
The Genetics of Alzheimer's Disease / Rudolph E. Tanzi --
Experimental Animal Models of Alzheimer's Disease / Dave Morgan Structural, Functional and Molecular Neuroimaging Biomarkers for Alzheimer's Disease / James B. Brewer, Jorge Sepulcre and Keith A. Johnson --
Fluid Biomarkers for Alzheimer's Disease / Anne M. Fagan --
Current Therapies for Alzheimer's Disease / Mary Sano and Judith A. Neugroschl --
Disease-Modifying Therapies for Alzheimer's Disease / Joshua D. Grill and Jeffrey Cummings --
Lewy Body Dementias / Stella Karantzoulis and James E. Galvin --
Clinical Features and Pathogenesis of FTD / Georges Naasan and Bruce Miller --
Pathogenesis, Diagnosis and Treatment of Vascular and Mixed Dementias / Helena Chang Chui --
Clinical Features and Pathogenesis of Prion Disease / Joel Watts and Michael D. Geschwind --
SECTION 8: Psychiatric Disorders of Childhood Onset / Joseph D. Buxbaum --
Epidemiology of Neuropsychiatric and Developmental Disorders of Childhood / Elise Robinson, Benjamin Neale and Mark J. Daly --
Rare Variants of Substantial Effect in Psychiatric Disorders of Childhood Onset / Heather C. Mefford --
Epigenetics in Early Life Programming / Tracy L. Bale --
Animal Models in Psychiatric Disorders of Childhood Onset / Richard Paylor, Alexia M. Thomas, Surabi Veeraragavan and Shannon M. Hamilton --
Neuropathology and Synaptic Alterations in Neurodevelopmental Disorders / Mara Dierssen and Salvador Martínez --
Functional Connectivity: Application to Developmental Disorders / Luke Bloy, Ragini Verma and Timothy P.L. Roberts --
Intellectual Disability Syndromes / Charles E. Schwartz, Fiorella Gurrieri and Giovanni Neri --
Autism Spectrum Disorders / Alexander Kolevzon, A. Ting Wang, David Grodberg and Joseph D. Buxbaum --
Neurobiology of Attention Deficit Hyperactivity Disorder / Stephen V. Faraone and Joseph Biederman --
Tourette Syndrome and Tic Disorders / Kyle Williams, Michael H. Bloch, Matthew W. State and Christopher Pittenger --
Novel Therapeutics in Childhood Onset Psychiatric Disorders / Dorothy E. Grice, Alexander Kolevzon, Walter E. Kaufmann and Joseph D. Buxbaum --
SECTION 9: Special Topic Areas / Dennis S. Charney --
DSM-5 Overview and Goals / David J. Kupfer and Susan K. Schultz --
The Infirmities of Psychiatric Diagnosis / Steven E. Hyman --
Toward Precision Medicine in Psychiatry: The NIMH Research Domain Criteria Project / Bruce N. Cuthbert and Thomas R. Insel --
Neurobiology of Personality Disorders: The Shift in DSM-5 / M. Mercedes Perez-Rodriguez, Antonia S. New and Larry J. Siever --
The Neurobiology of Aggression / James R. Blair --
Neurobiology of Social Attachment / Adam S. Smith, Kelly Lei and Zuoxin Wang --
The Neurobiology of Sleep / Giulio Tononi and Chiara Cirelli --
The Neurobiology of Resilience / Adriana Feder, Margaret Haglund, Gang Wu, Steven M. Southwick and Dennis S. Charney --
Neurobiology of Eating Disorders / Thomas B. Hildebrandt.