Molecular Mechanisms of Photoreceptor Transduction 9780121533151, 0121533158, 9780080584867


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English Pages ii-xx, 3-452 [481] Year 1981

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Table of contents :
Content:
Advisory Board
Page ii

Edited by
Page iii

Copyright page
Page iv

Yale Membrane Transport Processes Volumes
Page xi

List of Contributors
Pages xv-xviii

Preface
Pages xix-xx
William H. Miller

Chapter 1 The Photocurrent and Dark Current of Retinal Rods Original Research Article
Pages 3-18
G. Matthews, D.A. Baylor

Chapter 2 Spread of Excitation and Background Adaptation in the Rod Outer Segment Original Research Article
Pages 19-31
K.-W. Yau, T.D. Lamb, P.A. McNaughton

Chapter 3 Ionic Studies of Vertebrate Rods Original Research Article
Pages 33-57
W. Geoffrey Owen, Vincent Torre

Chapter 4 Photoreceptor Coupling: Its Mechanism and Consequences Original Research Article
Pages 59-89
Geoffrey H. Gold

Chapter 5 First Stage of Amplification in the Cyclic-Nucleotide Cascade of Vision Original Research Article
Pages 93-108
Lubert Stryer, James B. Hurley, Bernard K.-K. Fung

Chapter 6 Rod Guanylate Cyclase Located in Axonemes Original Research Article
Pages 109-119
Darrell Fleischman

Chapter 7 Light Control of Cyclic-Nucleotide Concentration in the Retina Original Research Article
Pages 121-132
Thomas G. Ebrey, Paul Kilbride, James B. Hurley, Roger Calhoon, Motoyukl Tsuda

Chapter 8 Cyclic-GMP Phosphodiesterase and Calmodulin in Early-Onset Inherited Retinal Degenerations Original Research Article
Pages 133-156
G.J. Chader, Y.P. Liu, R.T. Fletcher, G. Aguirre, R. Santos-Anderson, M. T'so

Chapter 9 Control of Rod Disk Membrane Phosphodiesterase and a Model for Visual Transduction Original Research Article
Pages 157-170
P.A. Liebman, E.N. Pugh Jr.

Chapter 10 Interactions of Rod Cell Proteins with the Disk Membrane: Influence of Light, Ionic Strength, and Nucleotides Original Research Article
Pages 171-201
Hermann Kühn

Chapter 11 Biochemical Pathways Regulating Transduction in Frog Photoreceptor Membranes Original Research Article
Pages 203-214
M. Deric Bownds

Chapter 12 The Use of Incubated Retinas in Investigating the Effects of Calcium and Other Ions on Cyclic-Nucleotide Levels in Photoreceptors Original Research Article
Pages 215-229
Adolph I. Cohen

Chapter 13 Cyclic AMP: Enrichment in Retinal Cones Original Research Article
Pages 231-235
Debora B. Farber

Chapter 14 Cyclic-Nucleotide Metabolism in Vertebrate Photoreceptors: A Remarkable Analogy and an Unraveling Enigma Original Research Article
Pages 237-271
M.W. Bitensky, G.L. Wheeler, A. Yamazaki, M.M. Rasenick, P.J. Stein

Chapter 15 Guanosine Nucleotide Metabolism in the Bovine Rod Outer Segment: Distribution of Enzymes and a Role of GTP Original Research Article
Pages 273-289
Hitoshi Shichi

Chapter 16 Calcium Tracer Exchange in the Rods of Excised Retinas Original Research Article
Pages 291-305
Ete Z. Szuts

Chapter 17 The Regulation of Calcium in the Intact Retinal Rod: A Study of Light-Induced Calcium Release by the Outer Segment Original Research Article
Pages 307-330
Geoffrey H. Gold, Juan I. Korenbrot

Chapter 18 Modulation of Sodium Conductance in Photoreceptor Membranes by Calcium Ions and cGMP Original Research Article
Pages 331-338
Robert T. Sorbi

Chapter 19 Calcium and the Mechanism of Light Adaptation in Rods Original Research Article
Pages 341-368
Bruce L. Bastian, Gordon L. Fain

Chapter 20 Effects of Cyclic Nucleotides and Calcium Ions on Bufo Rods Original Research Article
Pages 369-380
Joel E. Brown, Geraldine Waloga

Chapter 21 The Relation between Ca2+ and Cyclic GMP in Rod Photoreceptors Original Research Article
Pages 381-392
Stuart A. Lipton, John E. Dowling

Chapter 22 Limits on the Role of Rhodopsin and cGMP in the Functioning of the Vertebrate Photoreceptor Original Research Article
Pages 393-404
Sanford E. Ostroy, Edward P. Meyertholen, Peter J. Stein, Roberta A. Svoboda, Meegan J. Wilson

Chapter 23 [Ca2+]i Modulation of Membrane Sodium Conductance in Rod Outer Segments Original Research Article
Pages 405-416
Burks Oakley II, Lawrence H. Pinto

Chapter 24 Cyelie-GMP-lndueed Depolarization and Increased Response Latency of Rods: Antagonism by Light Original Research Article
Pages 417-437
William H. Miller, Grant D. Nicol

Chapter 25 Ca2+ and cGMP Original Research Article
Pages 441-445
William H. Miller

Index
Pages 447-452

Molecular Mechanisms of Photoreceptor Transduction
 9780121533151, 0121533158, 9780080584867

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