Enzyme Systems that Metabolise Drugs and Other Xenobiotics [1 ed.] 9780471894667, 0-471-89466-4
This definitive reference work describes in detail the enzyme systems that participate in the metabolism of xenobiotics,
175 88 358KB
English Pages 589 Year 2002
Table of contents :
Cover Page......Page 1
Current Toxicology Series......Page 3
Title Page......Page 4
Edition Info......Page 5
Contents......Page 6
Contributors......Page 8
Foreword......Page 10
1 Xenobiotic Metabolism: An Overview......Page 11
2 Cytochrome P450......Page 43
3 Flavin Monooxygenases......Page 77
4 Amine Oxidases and the Metabolism of Xenobiotics......Page 105
5 Molybdenum Hydroxylases......Page 157
6 Prostaglandin Synthases......Page 199
7 Lipoxygenases......Page 241
8 UDP-Glucuronosyltransferases......Page 291
9 Glutathione S-transferases......Page 329
10 Sulphotransferases......Page 363
11 Arylamine Acetyltransferases......Page 451
12 Mammalian Xenobiotic Epoxide Hydrolases......Page 469
13 Methyltransferases......Page 495
14 The Amino Acid Conjugations......Page 511
15 Deconjugating Enzymes; Sulphatases and Glucuronidases......Page 531
16 Nitroreductases and Azoreductases......Page 565
Index......Page 577
Back Page......Page 589
Cover Page......Page 1
Current Toxicology Series......Page 3
Title Page......Page 4
Edition Info......Page 5
Contents......Page 6
Contributors......Page 8
Foreword......Page 10
1 Xenobiotic Metabolism: An Overview......Page 11
2 Cytochrome P450......Page 43
3 Flavin Monooxygenases......Page 77
4 Amine Oxidases and the Metabolism of Xenobiotics......Page 105
5 Molybdenum Hydroxylases......Page 157
6 Prostaglandin Synthases......Page 199
7 Lipoxygenases......Page 241
8 UDP-Glucuronosyltransferases......Page 291
9 Glutathione S-transferases......Page 329
10 Sulphotransferases......Page 363
11 Arylamine Acetyltransferases......Page 451
12 Mammalian Xenobiotic Epoxide Hydrolases......Page 469
13 Methyltransferases......Page 495
14 The Amino Acid Conjugations......Page 511
15 Deconjugating Enzymes; Sulphatases and Glucuronidases......Page 531
16 Nitroreductases and Azoreductases......Page 565
Index......Page 577
Back Page......Page 589
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