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A disease is defined as rare if the prevalence is fewer than 200,000 in the United States. It is estimated that there ar
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Already popular in the analysis of medical device trials, adaptive Bayesian designs are increasingly being used in drug
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A health disparity refers to a higher burden of illness, injury, disability, or mortality experienced by one group relat
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In clinical trial practice, controversial statistical issues inevitably occur regardless of the compliance with good sta
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The US Food and Drug Administration's Report to the Nation in 2004 and 2005 indicated that one of the top reasons f
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A collection of highly valuable statistical and computational approaches designed for developing powerful methods to ana
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Featuring international contributors from both industry and academia, Numerical Methods for Finance explores new and rel
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This book provides a broad overview of rare disease drug development. It offers unique insights from various perspective
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Focusing on the practical clinical and statistical issues that arise in pharmaceutical industry trials, this book summar
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