Conn’s Handbook of Models for Human Aging [2 ed.]

Table of contents :
I. Aging in Humans
Chapter 1. Werner Syndrome as a model of human aging
Chapter 2. Premature aging syndrome
Chapter 3. Models, Definitions, and Criteria of Frailty
Chapter 4. Immunological methods and the concept of inflamm-aging in the study of human aging
Chapter 5. VULNERABILITY AND EXPERIENTIAL HEALTH IN OLD AGE – a qualitative perspective
Chapter 6. Body composition analysis in older adults
Chapter 7. Using Computational Models to Study Aging
Chapter 8. A framework for uncovering the roles of calories and macronutrients in health and aging
Chapter 9. Female Reproductive Aging: From Consequences to Mechanisms, Markers, and Treatments
Chapter 10. Adrenopause
Chapter 11. What sets Iceland apart in understanding human aging
II. Animal models: Vertebrates
Chapter 12. Reproductive Tract Lesions in Aged Chimpanzees
Chapter 13. Age-related changes to the bony structure and musculature of the shoulder in a nonhuman primate model
Chapter 14. The dog as a model for aging research
Chapter 15. Dogs as a Spontaneous Model for Early Alzheimer's Disease
Chapter 16. Determining cause of death and contributing causes of death in rodent aging studies
Chapter 17. Rat Models of Cognitive Aging
Chapter 18. Life Extension in Dwarf Mice
Chapter 19. Extension of Lifespan in Laboratory Mice
Chapter 20. Development and Validation of ECG analysis algorithm in mice
Chapter 21. Old mouse lemur: behavior, cognition and neuropathology
Chapter 22. Birds as models for the biology of aging and aging-related disease: an update
Chapter 23. Telomeres and Telomerase in Birds: Measuring Health, Environmental Stress and Longevity
Chapter 24. Zebrafish model for investigating the integrated control of reproduction
Chapter 25. Modelling aging and age-associated pathology in zebrafish
Chapter 26. The use of mature zebrafish (Danio rerio) as a model for human aging and disease
Chapter 27. Piscine polemics; Small tropical fish species as models for aging research
Chapter 28. The short-lived African turquoise killifish (Nothobranchius furzeri): a new model system for research on aging
III. Cellular models and invertebrates
Chapter 29. A Budding Topic: Modeling Aging and Longevity in Yeast
Chapter 30. The Budding and Fission Yeast Model Systems for Aging Biology: Rapid Advancement with New Technologies
Chapter 31. Podospora anserina: a filamentous fungus with a strong mitochondrial etiology of aging
Chapter 32. Invertebrates as model organisms for research on aging biology
Chapter 33. Invertebrate models for the study of the effects of age on neurotransmitter release
Chapter 34. Impact of Chronic Exercise on Invertebrate Functional Aging
Chapter 35. The virtues and challenges of multidimensional analyses of whole brains during aging with single cell resolution
Chapter 36. Rotifers as a Model for the Biology of Aging
Chapter 37. The Potential of Comparative Biology to Reveal Mechanisms of Aging in Rotifers
Chapter 38. Hydra, a model system for deciphering the mechanisms of aging and resistance to aging
Chapter 39. Regeneration and Aging in The Tunicate Ciona intestinalis
Chapter 40. Honeybee Workers as Models of Aging
IV. Disease models
Chapter 41. APPROACHES TO THE ASSESSMENT OF FRAILTY IN ANIMAL MODELS
Chapter 42. Genotype and sex differences in life expectancy in transgenic AD mice
Chapter 43. Animal models of vascular cognitive impairment and dementia
Chapter 44. ALZHEIMER’S DEMENTIA DRUG DISCOVERY: TARGETING SYNAPTIC GLUTAMATE UPTAKE
Chapter 45. A Transgenic Monkey Model of Huntington’s Disease
Chapter 46. PARKINSON’S DISEASE IN HUMANS AND IN NON-HUMAN PRIMATE AGING AND NEUROTOXIN MODELS
Chapter 47. GENETIC MODELS OF PARKINSON’S DISEASE AND THEIR STUDY IN NON-HUMAN PRIMATES
Chapter 48. Impact of the Aged Brain Environment on Gene Therapy for Parkinson’s Disease
Chapter 49. Cell Therapy for Parkinson's Disease
Chapter 50. Genetics of progeria and aging
Chapter 51. Progeria mouse models
Chapter 52. Models of Hypertension in Aging
Chapter 53. Osteoporosis and Cardiovascular Disease in the Elderly
Chapter 54. The role of the tumor microenvironment in pancreatic ductal adenocarcinoma and preclinical models to study it
V. Organ systems
Chapter 55. Alopecia
Chapter 56. Experimental Models of human skin aging
Chapter 57. Muscle deconditioning and aging: experimental models
Chapter 58. Models of Immune Aging
Chapter 59. Sex and the aging immune system
Chapter 60. Rodent Models of Ovarian Failure
Chapter 61. ROLE OF SEX AND AGING IN MUCOSAL HEALTH
Chapter 62. Leydig Cell Development and Aging in the Brown Norway Rat: Mechanisms and Consequences
Chapter 63. Models of aging Kidney: Implications on kidney health and disease
Chapter 64. AGE-ASSOCIATED CHANGES IN STRUCTURE AND FUNCTION OF THE AGING HUMAN LUNG
Chapter 65. Glucose, insulin and brain aging
Chapter 66. Pathology of brain aging and animal models of neurodegenerative diseases
Chapter 67. Leptin and aging in animal models
Chapter 68. Age-Related Changes to Bone Structure and Quality in Rodent Models
VI. Mechanisms
Chapter 69. Dielectric properties of biological tissues; variation with age
Chapter 70. Experimental Models of Tau Aggregation
Chapter 71. Aging of Human Mesenchymal Stem Cells
Chapter 72. Helicases and their relevance to aging
Chapter 73. Genetics of human aging
Chapter 74. Epigenetics of brain Aging
Chapter 75. The Circadian Clock and the Aging Process
Chapter 76. Super DNAging-New insights into DNA integrity, genome stability and telomeres in the oldest old
Chapter 77. Model of Chaperones in Aging
Chapter 78. Chaperone-mediated autophagy
Chapter 79. Resveratrol in Aging and Age-Related Diseases
Chapter 80. Resveratrol in experimental models and humans