Bioinformatics Research and Applications: 6th International Symposium, ISBRA 2010, Storrs, CT, USA, May 23-26, 2010. Proceedings [1 ed.] 3642130771, 9783642130779

Table of contents :
Front Matter....Pages -
Tracing the Early Cell Divisions of Mouse Embryos by Single Cell RNA-Seq....Pages 1-1
Successes and Failures of Elegant Algorithms in Computational Biology....Pages 2-2
Modeling without Borders: Creating and Annotating VCell Models Using the Web....Pages 3-17
Touring Protein Space with Matt....Pages 18-28
Fixed-Parameter Algorithm for General Pedigrees with a Single Pair of Sites....Pages 29-37
Analysis of Temporal-spatial Co-variation within Gene Expression Microarray Data in an Organogenesis Model....Pages 38-49
Human Genome Annotation....Pages 50-51
Extensions and Improvements to the Chordal Graph Approach to the Multi-state Perfect Phylogeny Problem....Pages 52-60
Analysis of Gene Interactions Using Restricted Boolean Networks and Time-Series Data....Pages 61-76
Residue Contexts: Non-sequential Protein Structure Alignment Using Structural and Biochemical Features....Pages 77-88
Essential Proteins Discovery from Weighted Protein Interaction Networks....Pages 89-100
Identifying Differentially Abundant Metabolic Pathways in Metagenomic Datasets....Pages 101-112
A Novel Approach for Compressing Phylogenetic Trees....Pages 113-124
Structure of Proximal and Distant Regulatory Elements in the Human Genome....Pages 125-125
Combinatorics in Recombinational Population Genomics....Pages 126-127
Uncovering Hidden Phylogenetic Consensus....Pages 128-139
An Agglomerate Algorithm for Mining Overlapping and Hierarchical Functional Modules in Protein Interaction Networks....Pages 140-151
Fast Protein Structure Alignment....Pages 152-165
Predicting and Analyzing Cellular Networks....Pages 166-166
A Consensus Tree Approach for Reconstructing Human Evolutionary History and Detecting Population Substructure....Pages 167-178
Inferring Evolutionary Scenarios for Protein Domain Compositions....Pages 179-190
Local Structural Alignment of RNA with Affine Gap Model....Pages 191-202
Fast Computation of the Exact Hybridization Number of Two Phylogenetic Trees....Pages 203-214
“Master-Slave” Biological Network Alignment....Pages 215-229
Deciphering Transcription Factor Binding Patterns from Genome-Wide High Density ChIP-chip Tiling Array Data....Pages 230-240
The Expected Fitness Cost of a Mutation Fixation under the One-Dimensional Fisher Model....Pages 241-252
Back Matter....Pages -