Bioinformatics: Concepts, Methodologies, Tools, and Applications 1466636041, 9781466636040

Table of contents :
Section 1: Fundamental Concepts and Theories
#1. Overview of Biomedical Engineering
#2. Evaluating a Genetics Concept Inventory
#3. Overview of Knowledge Discovery in Databases Process and Data Mining for Surveillance Technologies and EWS
#4. A Review of Kernel Methods Based Approaches to Classification and Clustering of Sequential Patterns: Sequences of Discrete Symbols
#5. GO-Based Term Semantic Similarity
#6. Parallel Evolutionary Computation in R
#7. Developing a Library Collection in Bioinformatics: Support for an Evolving Profession
#8. Linking Interactome to Disease: A Network-Based Analysis of Metastatic Relapse in Breast Cancer
#9. Knowledge-Driven, Data-Assisted Integrative Pathway Analytics
#10. Medical Informatics and Bioinformatics
#11. An Overview of Graph Indexing and Querying Techniques
#12. Genomics and Population Health: A Social Epidemiology Perspective
#13. Genomics and Genetic Engineering: Playing God?
#14. The Important Role of Lipids in Cognitive Impairment
#15. Virtual Worlds for Teaching: A Comparison of Traditional Methods and Virtual Worlds for Science Instruction
#16. Data Intensive Computing for Bioinformatics
#17. From Bench to Bedside: BACE1, Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1, From Basic Science to Clinical Investigation

Section 2: Tools and Technologies
#18. Analysis and Prediction of DNA-Recognition by Zinc Finger Proteins: Applications in Genome Modification
#19. Web Services for Bioinformatics
#20. Learning Binding Affinity from Augmented High Throughput Screening Data
#21. Protein Homology Analysis for Function Prediction with Parallel Sub-Graph Isomorphism
#22. Techniques for Named Entity Recognition: A Survey
#23. Neuroimaging in Alzheimer’s Disease
#24. Neuronal Transcytosis of WGA Conjugated Protein: A New Approach to Amyloid-ß In Vivo
#25. Noninvasive Detection of Misfolded Proteins in the Brain Using [11C]BF-227 PET
#26. Graph Mining Techniques: Focusing on Discriminating between Real and Synthetic Graphs
#27. Current Omics Technologies in Biomarker Discovery
#28. Prediction of Epigenetic Target Sites by Using Genomic DNA Sequence
#29. Biclustering of DNA Microarray Data: Theory, Evaluation, and Applications
#30. Unsupervised Methods to Identify Cellular Signaling Networks from Perturbation Data
#31. Cross-Platform Microarray Data Integration Combining Meta-Analysis and Gene Set Enrichment Analysis
#32. Chemosensitivity Prediction of Tumours based on Expression, miRNA, and Proteomics Data
#33. FPGA-Based Accelerators for Bioinformatics Applications

Section 3: Frameworks and Methodologies
#34. Modules in Biological Networks: Identification and Application
#35. A Framework for Networked Experiments in Global E-Science: Perspectives for E-Learning in Global Contexts
#36. Complexity and Modularity of MAPK Signaling Networks
#37. Using Systems Biology Approaches to Predict New Players in the Innate Immune System
#38. Addressing the Challenges of Detecting Epistasis in Genome-Wide Association Studies of Common Human Diseases Using Biological Expert Knowledge
#39. Connecting Microbial Population Genetics with Microbial Pathogenesis: Engineering Microfluidic Cell Arrays for High-Throughput Interrogation of Host-Pathogen Interaction
#40. Hybrid Neural Genetic Architecture: New Directions for Intelligent Recommender System Design
#41. A Two-Layer Learning Architecture for Multi-Class Protein Folds Classification
#42. The Mathematical Modeling and Computational Simulation for Error-Prone PCR
#43. Using a Genetic Algorithm and Markov Clustering on Protein–Protein Interaction Graphs
#44. Kernel Generative Topographic Mapping of Protein Sequences
#45. Incorporating Correlations among Gene Ontology Terms into Predicting Protein Functions
#46. Bifurcation Analysis of a Model Accounting for the 14-3-3s Signalling Compartmentalisation
#47. Engineering Gene Control Circuits with Allosteric Ribozymes in Human Cells as a Medicine of the Future
#48. Computational Sequence Design Techniques for DNA Microarray Technologies

Section 4: Cases and Applications
#49. Can Activated Platelet Rich Plasma Combined with Adipose-Derived Stem Cells Be Used to Treat Skin Wrinkles?: A Mechanism Study
#50. Analysis of Kinase Inhibitors and Druggability of Kinase-Targets Using Machine Learning Techniques
#51. In Silico Pharmaco-Gene-Informatic Identification of Insulin-Like Proteins in Plants
#52. Molecular Network Analysis of Target RNAs and Interacting Proteins of TDP-43, a Causative Gene for the Neurodegenerative Diseases ALS/FTLD
#53. Chemoinformatics on Metabolic Pathways: Attaching Biochemical Information on Putative Enzymatic Reactions
#54. Improving Prediction Accuracy via Subspace Modeling in a Statistical Geometry Based Computational Protein Mutagenesis
#55. Resolving Sample Traces in Complex Mixtures with Microarray Analyses
#56. Predictive Dynamical Modelling MicroRNAs Role in Complex Networks
#57. Decision Support Systems in the Process of Improving Patient Safety
#58. Graph Applications in Chemoinformatics and Structural Bioinformatics
#59. Visualization of Protein 3D Structures in ‘Double-Centroid’ Reduced Representation: Application to Ligand Binding Site Modeling and Screening
#60. JFeature: A Java Package for Extracting Global Sequence Features from Proteins for Functional Classification
#61. Evaluation of Coupled Nuclear and Cytoplasmic p53 Dynamics
#62. Data Mining and Meta-Analysis on DNA Microarray Data
#63. Efficient Computational Construction of Weighted Protein-Protein Interaction Networks Using Adaptive Filtering Techniques Combined with Natural Selection-Based Heuristic Algorithms
#64. BMP Signaling in Regenerative Medicine

Section 5: Issues and Challenges
#65. Certification and Security Issues in Biomedical Grid Portals: The GRISSOM Case Study
#66. A Comparative Study of an Unsupervised Word Sense Disambiguation Approach
#67. The Impact of Genetic Testing and Genetic Information on Ethical, Legal and Social Issues in North America: The Framework
#68. The Applications of Omics Technologies and the Challenges of Ethics in Nutritional Sciences
#69. A Philosophical Exploration of the Concept of ‘Property’ in Genetics and Databanking: Challenges for Bioethics in Asia and Europe
#70. Genomics Perspectives of Bioethanol Producing Zymomonas Mobilis
#71. Ethics and Privacy Considerations for Systems Biology Applications in Predictive and Personalized Medicine
#72. Ethics, Privacy, and the Future of Genetic Information in Healthcare Information Assurance and Security
#73. Risk-Benefit Analysis of Combination vs. Unopposed HRT in Post-Menopausal Women
#74. Plastika [Totipotenta]
#75. Pharmacovigilance: Basic Concepts and Applications of Pharmacoinformatics
#76. Language Focus for Genetics and Molecular Biology Students
#77. Data Analysis and Interpretation in Metabolomics
#78. Promoter Structures Conserved between Homo Sapiens, Mus Musculus and Drosophila Melanogaster

Section 6: Emerging Trends
#79. A New Approach for Sequence Analysis: Illustrating an Expanded Bioinformatics View through Exploring Properties of the Prestin Protein
#80. Aß Monomer, Oligomer and Fibril in Alzheimer’s Disease
#81. BTISNet: Biotechnology Information Network for Biological Scientific Community
#82. Intelligent Classifiers Fusion for Enhancing Recognition of Genes and Protein Pattern of Hereditary Diseases
#83. Mining Statistically Significant Substrings based on the Chi-Square Measure
#84. Semi-Supervised Clustering for the Identification of Different Cancer Types Using the Gene Expression Profiles
#85. Cancer Gene Expression Data Analysis Using Rough Based Symmetrical Clustering
#86. Computational Methods for Identification of Novel Secondary Metabolite Biosynthetic Pathways by Genome Analysis
#87. Improving PSI-BLAST’s Fold Recognition Performance through Combining Consensus Sequences and Support Vector Machine
#88. Towards Optimal Microarray Universal Reference Sample Designs: An In-Silico Optimization Approach
#89. Gene Expression Regulation underlying Osteo-, Adipo-, and Chondro-Genic Lineage Commitment of Human Mesenchymal Stem Cells
#90. Quantum Computing Approach for Alignment-Free Sequence Search and Classification
#91. An Approach for Biological Data Integration and Knowledge Retrieval Based on Ontology, Semantic Web Services Composition, and AI Planning
#92. An Optimization to Protein Coding Regions Identification in Eukaryotes
#93. Use of SciDBMaker as Tool for the Design of Specialized Biological Databases
#94. Emerging Web Tools and Their Applications in Bioinformatics